Contemporary insights and novel treatment approaches to central sleep apnea syndrome in heart failure

Current Treatment Options in Cardiovascular Medicine

Volumn 16, Issue 7, 2014, Pages

  Grayburn, Ryan L ^a   Kaka, Yaquta ^b   Tang, W H Wilson ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b NORTHEAST OHIO MEDICAL UNIVERSITY   (United States)

Author keywords

Central sleep apnea syndrome; Cheyne Stokes respiration; Heart failure; Treatment options

Indexed keywords

ACETAZOLAMIDE; HYPNOTIC SEDATIVE AGENT; OXYGEN; PLACEBO; PROGESTERONE; THEOPHYLLINE;

APNEA HYPOPNEA INDEX; AROUSAL; BREATHING PATTERN; CARDIAC RESYNCHRONIZATION THERAPY; CENTRAL SLEEP APNEA SYNDROME; CHEMORECEPTOR; CHEYNE STOKES BREATHING; CLINICAL TRIAL (TOPIC); COGNITION; COMPRESSION STOCKING; DISEASE COURSE; DISEASE SEVERITY; EXERCISE; EXERCISE TEST; FATIGUE; GAS EXCHANGE; HEART FAILURE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FAILURE; HOSPITALIZATION; HUMAN; HYPERVENTILATION; HYPOVENTILATION; INTERNATIONAL CLASSIFICATION OF SLEEP DISORDERS; KIDNEY FAILURE; LIFESTYLE MODIFICATION; LUNG ALVEOLUS HYPOVENTILATION; LUNG CONGESTION; MORBIDITY; MORTALITY; NEUROLOGIC DISEASE; NEW YORK HEART ASSOCIATION CLASS; OXYGEN DESATURATION; PATHOPHYSIOLOGY; POLYSOMNOGRAPHY; POSITIVE END EXPIRATORY PRESSURE; PRACTICE GUIDELINE; PULMONARY ARTERY OCCLUSION PRESSURE; QUALITY OF LIFE; RESPIRATION CONTROL; REVIEW; SLEEP DISORDERED BREATHING; SLEEP QUALITY; SYMPATHETIC TONE; UPPER RESPIRATORY TRACT OBSTRUCTION; VOICE CHANGE;

EID: 84901576684     PISSN: 10928464     EISSN: 15343189     Source Type: Journal    
DOI: 10.1007/s11936-014-0322-5     Document Type: Review

References (66)

1. .• Aurora RN, Chowdhuri S, Ramar K, et al. The treatment of central sleep apnea syndromes in adults: practice parameters with an evidence-based literature review and meta-analyses. Sleep. 2012;35(1):17-40. Comprehensive summary from American Association of Sleep Medicine on treatment options for CSA
2. Gastaut H, Tassinari CA, Duron B. Etude polygraphique des manifestations episodiques (hypniques et respiratoires) du syndrome de Pickwick. Rev Neurol (Paris). 1965;112(6):568-79.
3. Gastaut H, Tassinari CA, Duron B. Polygraphic study of the episodic diurnal and nocturnal (hypnic and respiratory) manifestations of the Pickwick syndrome. Brain Res. 1966;1(2):167-86.
4. American Academy of Sleep Medicine. International classification of sleep disorders, second edition: diagnostic and coding manual. Westchester: American Academy of Sleep Medicine; 2005.
5. Kuzniar TJ, Morgenthaler TI. Treatment of complex sleep apnea syndrome. Chest. 2012;142(4):1049-57.
6. Javaheri S, Smith J, Chung E. The prevalence and natural history of complex sleep apnea. J Clin Sleep Med. 2009;5(3):205-11.
7. .• Johansson P, Alehagen U, Svanborg E, Dahlstrom U, Brostrom A. Sleep disordered breathing in an elderly community-living population: relationship to cardiac function, insomnia symptoms and daytime sleepiness. Sleep Med. 2009;10(9):1005-11. Community-based study of Swedish elderly patients to clarify the prevalence of CSA using echocardiography and home-based sleep study
8. Javaheri S, Parker TJ, Liming JD, et al. Sleep apnea in 81 ambulatory male patients with stable heart failure. Types and their prevalences, consequences, and presentations. Circulation. 1998;97(21):2154-9. (Pubitemid 28262123)
9. Bitter T, Faber L, Hering D, Langer C, Horstkotte D, Oldenburg O. Sleep-disordered breathing in heart failure with normal left ventricular ejection fraction. Eur J Heart Fail. 2009;11(6):602-8.
10. Herrscher TE, AkreH,Overland B, Sandvik L,Westheim AS. High prevalence of sleep apnea in heart failure outpatients: even in patients with preserved systolic function. J Card Fail. 2011;17(5):420-5.
11. Mookadam F, Calvin AD, Somers VK. Prevalence and management of central sleep apnea in heart failure patients. Curr Heart Fail Rep. 2008;5(4):233-7.
12. Yumino D, Wang H, Floras JS, et al. Prevalence and physiological predictors of sleep apnea in patients with heart failure and systolic dysfunction. J Card Fail. 2009;15(4):279-85.
13. Dolliner P, Brammen L, Graf S, et al. Portable recording for detecting sleep disorder breathing in patients under the care of a heart failure clinic. Clin Res Cardiol. 2013;102:535-42.
14. Vazir A, Hastings PC, Dayer M, et al. A high prevalence of sleep disordered breathing in men with mild symptomatic chronic heart failure due to left ventricular systolic dysfunction. Eur J Heart Fail. 2007;9(3):243-50. (Pubitemid 46330138)
15. Tada T, Kusano KF, Ogawa A, et al. The predictors of central and obstructive sleep apnoea in haemodialysis patients. Nephrol Dial Transplant. 2007;22(4):1190-7. (Pubitemid 46523437)
16. Bonnin-Vilaplana M, Arboix A, Parra O, Garcia-Eroles L, Montserrat JM, Massons J. Sleep-related breathing disorders in acute lacunar stroke. J Neurol. 2009;256(12):2036 -42.
17. Parra O, Arboix A, Bechich S, et al. Time course of sleep-related breathing disorders in first-ever stroke or transient ischemic attack. AmJ Respir Crit CareMed. 2000;161(2 Pt 1):375-80. (Pubitemid 30129441)
18. Rowley JA, Zhou XS, Diamond MP, Badr MS. The determinants of the apnea threshold during NREM sleep in normal subjects. Sleep. 2006;29(1):95-103. (Pubitemid 44019034)
19. Zhou XS, Rowley JA, Demirovic F, Diamond MP, Badr MS. Effect of testosterone on the apneic threshold in women during NREM sleep. J Appl Physiol. 2003;94(1):101-7. (Pubitemid 36014301)
20. Mateika JH, Omran Q, Rowley JA, Zhou XS, Diamond MP, Badr MS. Treatment with leuprolide acetate decreases the threshold of the ventilatory response to carbon dioxide in healthy males. J Physiol. 2004;561(Pt 2):637-46. (Pubitemid 39646549)
21. Millman RP, Bevilacqua J, Peterson DD, Pack AI. Central sleep apnea in hypothyroidism. Am Rev Respir Dis. 1983;127(4):504-7. (Pubitemid 13083757)
22. Grunstein RR, Ho KY, Berthon-Jones M, Stewart D, Sullivan CE. Central sleep apnea is associated with increased ventilatory response to carbon dioxide and hypersecretion of growth hormone in patients with acromegaly. Am J Respir Crit Care Med. 1994;150(2):496-502. (Pubitemid 24252365)
23. Yumino D, Bradley TD. Central sleep apnea and Cheyne-Stokes respiration. Proc Am Thorac Soc. 2008;5(2):226-36. (Pubitemid 351237882)
24. Corra U, Pistono M, Mezzani A, et al. Sleep and exertional periodic breathing in chronic heart failure: prognostic importance and interdependence. Circulation. 2006;113(1):44-50. (Pubitemid 43958487)
25. Kremser CB, O'Toole MF, Leff AR. Oscillatory hyperventilation in severe congestive heart failure secondary to idiopathic dilated cardiomyopathy or to ischemic cardiomyopathy. Am J Cardiol. 1987;59(8):900 -5.
26. Corra U, Giordano A, Bosimini E, et al. Oscillatory ventilation during exercise in patients with chronic heart failure: clinical correlates and prognostic implications. Chest. 2002;121(5):1572-80. (Pubitemid 34499673)
27. Guazzi M, Arena R, Ascione A, Piepoli M, Guazzi MD. Exercise oscillatory breathing and increased ventilation to carbon dioxide production slope in heart failure: an unfavorable combination with high prognostic value. Am Heart J. 2007;153(5):859-67. (Pubitemid 46602158)
28. Piepoli MF, Ponikowski PP, Volterrani M, Francis D, Coats AJ. Aetiology and pathophysiological implications of oscillatory ventilation at rest and during exercise in chronic heart failure. Do Cheyne and Stokes have an important message for modern-day patients with heart failure? Eur Heart J. 1999;20(13):946-53. (Pubitemid 29281441)
29. Corra U, Mezzani A, Giordano A, Bosimini E, Giannuzzi P. Exercise haemodynamic variables rather than ventilatory efficiency indexes contribute to risk assessment in chronic heart failure patients treated with carvedilol. Eur Heart J. 2009;30(24):3000-6.
30. Guazzi M, Myers J, Peberdy MA, Bensimhon D, Chase P, Arena R. Exercise oscillatory breathing in diastolic heart failure: prevalence and prognostic insights. Eur Heart J. 2008;29(22):2751-9.
31. Badr S. Central sleep apnea in patients with congestive heart failure. Heart Fail Rev. 2009;14(3):135-41.
32. Bradley TD, Floras JS. Sleep apnea and heart failure: part II: central sleep apnea. Circulation. 2003;107(13):1822-6. (Pubitemid 36418366)
33. White DP. Pathogenesis of obstructive and central sleep apnea. Am J Respir Crit Care Med. 2005;172(11):1363-70. (Pubitemid 43069808)
34. Javaheri S. Central sleep apnea in congestive heart failure: prevalence, mechanisms, impact, and therapeutic options. Semin Respir Crit Care Med. 2005;26(1):44- 55.
35. Javaheri S. Central sleep apnea. Clin Chest Med. 2010;31(2):235 -48.
36. Lanfranchi PA, Somers VK, Braghiroli A, Corra U, Eleuteri E, Giannuzzi P. Central sleep apnea in left ventricular dysfunction: prevalence and implications for arrhythmic risk. Circulation. 2003;107(5):727-32. (Pubitemid 36222601)
37. White DP. Central sleep apnea. Med Clin N Am. 1985;69(6):1205-19. (Pubitemid 16199956)
38. Javaheri S. Treatment of central sleep apnea in heart failure. Sleep. 2000;23 Suppl 4:S224-7. (Pubitemid 30462691)
39. De Backer WA, Verbraecken J, Willemen M, Wittesaele W, DeCock W, Van de Heyning P. Central apnea index decreases after prolonged treatment with acetazolamide. Am J Respir Crit Care Med. 1995;151(1):87-91.
40. White DP, Zwillich CW, Pickett CK, Douglas NJ, Findley LJ, Weil JV. Central sleep apnea. Improvement with acetazolamide therapy. Arch Intern Med. 1982;142(10):1816-9. (Pubitemid 12036216)
41. Fontana M, Emdin M, Giannoni A, Iudice G, Baruah R, Passino C. Effect of acetazolamide on chemosensitivity, Cheyne-Stokes respiration, and response to effort in patients with heart failure. Am J Cardiol. 2011;107(11):1675- 80.
42. Kuzniar TJ, Golbin JM, Morgenthaler TI. Moving beyond empiric continuous positive airway pressure (CPAP) trials for central sleep apnea: a multi-modality titration study. Sleep Breath. 2007;11(4):259- 66.
43. Kimura H, Tatsumi K, Kunitomo F, et al. Obese patients with sleep apnea syndrome treated by progesterone. Tohoku J Exp Med. 1988;156(Suppl):151-7. (Pubitemid 19268923)
44. Eckert DJ, Jordan AS, Merchia P, Malhotra A. Central sleep apnea: pathophysiology and treatment. Chest. 2007;131(2):595-607. (Pubitemid 46280426)
45. Javaheri S, Parker TJ, Wexler L, Liming JD, Lindower P, Roselle GA. Effect of theophylline on sleep-disordered breathing in heart failure. N Engl J Med. 1996;335(8):562-7. (Pubitemid 26272311)
46. Garcia-Touchard A, Somers VK, Olson LJ, Caples SM. Central sleep apnea: implications for congestive heart failure. Chest. 2008;133(6):1495-504. (Pubitemid 351893011)
47. .• Bradley TD, Logan AG, Kimoff RJ, et al. Continuous positive airway pressure for central sleep apnea and heart failure. N Engl J Med. 2005;353(19):2025-33. Landmark CANPAP study showing the role of CPAP in central sleep apnea (Pubitemid 41609095)
48. .• Arzt M, Floras JS, Logan AG, et al. Suppression of central sleep apnea by continuous positive airway pressure and transplant-free survival in heart failure: a post hoc analysis of the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure Trial (CANPAP). Circulation. 2007;115(25):3173-80. Post-hoc analysis of the CANPAP study showing the potential benefit of CPAP in those that are compliant and achieved improvement in sleep parameters (Pubitemid 47012231)
49. Momomura S. Treatment of Cheyne-Stokes respiration-central sleep apnea in patients with heart failure. J Cardiol. 2012;59(2):110-6.
50. Hastings PC, Vazir A, Meadows GE, et al. Adaptive servo-ventilation in heart failure patients with sleep apnea: a real world study. Int J Cardiol. 2010;139(1):17-24.
51. Randerath WJ, Galetke W, Kenter M, Richter K, Schafer T. Combined adaptive servo-ventilation and automatic positive airway pressure (anticyclic modulated ventilation) in co-existing obstructive and central sleep apnea syndrome and periodic breathing. Sleep Med. 2009;10(8):898-903.
52. Cowie MR, Woehrle H, Wegscheider K, et al. Rationale and design of the SERVE-HF study: treatment of sleep-disordered breathing with predominant central sleep apnoea with adaptive servo-ventilation in patients with chronic heart failure. Eur J Heart Fail. 2013;15(8):937-43.
53. Andreas S, Weidel K, Hagenah G, Heindl S. Treatment of Cheyne-Stokes respiration with nasal oxygen and carbon dioxide. Eur Respir J. 1998;12(2):414- 9.
54. .• Giannoni A, Baruah R, Willson K, et al. Real-time dynamic carbon dioxide administration: a novel treatment strategy for stabilization of periodic breathing with potential application to central sleep apnea. J Am Coll Cardiol. 2010;56(22):1832-7. Stabilization of periodic breathing with dynamic CO2 administration
55. Mebrate Y, Willson K, Manisty CH, et al. Dynamic CO2 therapy in periodic breathing: a modeling study to determine optimal timing and dosage regimes. J Appl Physiol (1985). 2009;107(3):696-706.
56. Steens RD, Millar TW, Su X, et al. Effect of inhaled 3% CO2 on Cheyne-Stokes respiration in congestive heart failure. Sleep. 1994;17(1):61-8. (Pubitemid 24103642)
57. .• Ponikowski P, Javaheri S, Michalkiewicz D, et al. Transvenous phrenic nerve stimulation for the treatment of central sleep apnoea in heart failure. Eur Heart J. 2012;33(7):889-94. Early pilot data for effects of phrenic nerve stimulation in improving sleep indices in patients with CSA
58. Lindenfeld J, Albert NM, Boehmer JP, et al. HFSA 2010 Comprehensive Heart Failure Practice Guideline. J Card Fail. 2010;16(6):e1-e194.
59. Yancy CW, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2013;128(16):1810 -52.
60. Oldenburg O, Lamp B, Faber L, Teschler H, Horstkotte D, Topfer V. Sleep-disordered breathing in patients with symptomatic heart failure: a contemporary study of prevalence in and characteristics of 700 patients. Eur J Heart Fail. 2007;9(3):251-7. (Pubitemid 46335886)
61. Schulz R, Blau A, Borgel J, et al. Sleep apnoea in heart failure. Eur Respir J. 2007;29(6):1201-5. (Pubitemid 46895381)
62. MacDonald M, Fang J, Pittman SD, White DP, Malhotra A. The current prevalence of sleep disordered breathing in congestive heart failure patients treated with beta-blockers. J Clin Sleep Med. 2008;4(1):38-42. (Pubitemid 352038668)
63. Paulino A, Damy T, Margarit L, et al. Prevalence of sleep-disordered breathing in a 316-patient French cohort of stable congestive heart failure. Arch Cardiovasc Dis. 2009;102(3):169-75.
64. Hagenah G, Beil D. Prevalence of Cheyne-Stokes respiration in modern treated congestive heart failure. Sleep Breath. 2009;13(2):181-5.
65. Khayat R, Abraham W, Patt B, et al. Central sleep apnea is a predictor of cardiac readmission in hospitalized patients with systolic heart failure. J Card Fail. 2012;18(7):534-40.
66. Javaheri S, Shukla R, Zeigler H, Wexler L. Central sleep apnea, right ventricular dysfunction, and low diastolic blood pressure are predictors of mortality in systolic heart failure. J Am Coll Cardiol. 2007;49(20):2028- 34.