Highly efficient delivery of siRNA to a heart transplant model by a novel cell penetrating peptide-dsRNA binding domain

International Journal of Pharmaceutics

Volumn 469, Issue 1, 2014, Pages 206-213

  Li, Hua ^a,b   Zheng, Xiangtao ^a   Koren, Viktoria ^a   Vashist, Yogesh Kumar ^a   Tsui, Tung Yu ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b HUZHOU UNIVERSITY   (China)

Author keywords

Cell penetrating peptide; Double stranded RNA binding domain; Gene delivery; RNA interference

Indexed keywords

CALCIUM CHLORIDE; CELL PENETRATING PEPTIDE; DOUBLE STRANDED RNA; DOUBLE STRANDED RNA BINDING DOMAIN; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; GREEN FLUORESCENT PROTEIN; HYBRID PROTEIN; LIPOFECTAMINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; CALCIUM; PEPTIDE FRAGMENT; RNA BINDING PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CALCIUM CONDENSATION; CALCIUM METABOLISM; CONTROLLED STUDY; FEMALE; FLOW CYTOMETRY; GENE; GENE EXPRESSION; GENE SILENCING; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE GENE; GREEN FLUORESCENT PROTEIN GENE; HEART GRAFT; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; MOUSE MODEL; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CHEMISTRY; GENE EXPRESSION REGULATION; GENE THERAPY; GENE TRANSFER; GENETICS; HEART TRANSPLANTATION; METABOLISM; PROCEDURES; PROTEIN DOMAIN; REPORTER GENE; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CALCIUM; CELL-PENETRATING PEPTIDES; GENE EXPRESSION REGULATION; GENE TRANSFER TECHNIQUES; GENES, REPORTER; GENETIC THERAPY; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; GREEN FLUORESCENT PROTEINS; HEART TRANSPLANTATION; HELA CELLS; HUMANS; MALE; MICE, INBRED C57BL; PEPTIDE FRAGMENTS; PROTEIN INTERACTION DOMAINS AND MOTIFS; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; RNA, SMALL INTERFERING; RNA-BINDING PROTEINS;

EID: 84901471843     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.04.050     Document Type: Article

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