Marine compound catunaregin inhibits angiogenesis through the modulation of phosphorylation of Akt and eNOS in vivo and in vitro

Marine Drugs

Volumn 12, Issue 5, 2014, Pages 2790-2801

  Liu, Jun Xiu ^a   Luo, Min Qi ^a   Xia, Meng ^a   Wu, Qi ^a   Long, Si Mei ^a   Hu, Yaohua ^b   Gao, Guang Chun ^c   Yao, Xiao Li ^a   He, Mian ^a   Su, Huanxing ^b   Luo, Xiong Ming ^d   Yao, Shu Zhong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b University of Macau   (Macao)

^c JIAXING UNIVERSITY   (China)

^d SOUTH CHINA SEA INSTITUTE OF OCEANOLOGY   (China)

Author keywords

Anti angiogenesis; Catunaregin; HUVECs; VEGF; Zebrafish

Indexed keywords

ANGIOGENESIS INHIBITOR; CATUNAREGIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NATURAL PRODUCT; PROTEIN KINASE B; UNCLASSIFIED DRUG; VASCULOTROPIN; CATECHOL DERIVATIVE; LIGNAN; ONCOPROTEIN; VASCULOTROPIN A;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANTIANGIOGENIC ACTIVITY; ARTICLE; CELL INVASION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ISOLATION; EMBRYO; ENZYME PHOSPHORYLATION; FIN (ORGAN); HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; PHENOTYPE; REGENERATION; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; ZEBRA FISH; ANIMAL; ANIMAL EMBRYO; ANTAGONISTS AND INHIBITORS; CELL MOTION; CHEMISTRY; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; PHOSPHORYLATION; SIGNAL TRANSDUCTION;

ANGIOGENESIS INHIBITORS; ANIMAL FINS; ANIMALS; CATECHOLS; CELL MOVEMENT; EMBRYO, NONMAMMALIAN; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; LIGNANS; NITRIC OXIDE SYNTHASE TYPE III; ONCOGENE PROTEIN V-AKT; PHOSPHORYLATION; REGENERATION; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; ZEBRAFISH;

EID: 84901470949     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md12052790     Document Type: Article

References (12)

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