Marine cyclotripeptide X-13 promotes angiogenesis in zebrafish and human endothelial cells via PI3K/Akt/eNOS signaling pathways

Marine Drugs

Volumn 10, Issue 6, 2012, Pages 1307-1320

  Lu, Xi Lin ^a   Xu, Zhong Liang ^a   Yao, Xiao Li ^a   Su, Feng Juan ^a   Ye, Cheng Hui ^a   Li, Jing ^a   Lin, Yong Cheng ^a   Wang, Guang Lei ^b,c   Zeng, Jin Sheng ^a   Huang, Ru Xun ^a   Ou, Jing Song ^a,d   Sun, Hong Shuo ^e   Wang, Li Ping ^f   Pang, Ji Yan ^a   Pei, Zhong ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c Key Laboratory of Functional Molecules from Oceanic Microorganisms   (China)

^d BEIJING HOSPITAL   (China)

^e UNIVERSITY OF TORONTO   (Canada)

^f SHENZHEN INSTITUTES OF ADVANCED TECHNOLOGY   (China)

Author keywords

Angiogenesis; Endothelial nitric oxide synthase; Marine cyclotripeptide; Xyloallenoide A; Zebrafish

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; ANGIOGENIC FACTOR; CYCLOTRIPEPTIDE X 13; ENDOTHELIAL NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NATURAL PRODUCT; NITRIC OXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG; XYLOALLENOIDE A;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG EFFECT; DRUG ISOLATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; EMBRYO; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; SIGNAL TRANSDUCTION; STRUCTURE ANALYSIS; UMBILICAL VEIN ENDOTHELIAL CELL; ZEBRA FISH;

DANIO RERIO; FUNGI; XYLARIA;

EID: 84863463774     PISSN: None     EISSN: 16603397     Source Type: Journal    
DOI: 10.3390/md10061307     Document Type: Article

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