Cdk5-dependent Mst3 phosphorylation and activity regulate neuronal migration through RhoA inhibition

Journal of Neuroscience

Volumn 34, Issue 22, 2014, Pages 7425-7436

  Tang, Jing ^a   Ip, Jacque P K ^a   Ye, Tao ^a   Ng, Yu Pong ^a   Yung, Wing Ho ^b   Wu, Zhenguo ^a   Fang, Weiqun ^a   Fu, Amy K Y ^a   Ip, Nancy Y ^a  

^a HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Hong Kong)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Actin; Cyclin dependent kinase; Neuronal migration; Rho GTPase

Indexed keywords

ACTIN; COMPLEMENTARY DNA; CYCLIN DEPENDENT KINASE 5; MST3 PROTEIN; PROTEIN KINASE; PROTEIN SERINE THREONINE KINASE; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SHORT HAIRPIN RNA; UNCLASSIFIED DRUG;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; CELL ASSAY; CELL MIGRATION; CONTROLLED STUDY; ELECTROPORATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE SILENCING; GENETIC TRANSFECTION; IMMUNOPRECIPITATION; IN VITRO STUDY; MOUSE; NERVE CELL; NERVE CELL CULTURE; NEURONAL MIGRATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXTRACTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REGULATORY MECHANISM; SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

ACTIN; CYCLIN-DEPENDENT KINASE; NEURONAL MIGRATION; RHO-GTPASE;

AMINO ACID SEQUENCE; ANIMALS; ANIMALS, NEWBORN; CELL MOVEMENT; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE 5; ENZYME ACTIVATION; FEMALE; HEK293 CELLS; HUMANS; MALE; MICE; MICE, INBRED ICR; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; NEOCORTEX; NERVE TISSUE PROTEINS; NEURONS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RATS; RHO GTP-BINDING PROTEINS;

EID: 84901463337     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5449-13.2014     Document Type: Article

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