Phenethyl isothiocyanate inhibits growth of human chronic myeloid leukemia K562 cells via reactive oxygen species generation and caspases

Molecular Medicine Reports

Volumn 10, Issue 1, 2014, Pages 543-549

  Wang, Yating ^a   Wei, Sixi ^a   Wang, Jishi ^a   Fang, Qin ^a   Chai, Qixiang ^a  

^a GUIZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Apoptosis; HO 1; K562; Phenethyl isothiocyanate; ROS

Indexed keywords

CASPASE; CASPASE 3; CASPASE 9; CYTOCHROME C; FAS ANTIGEN; FAS LIGAND; HEME OXYGENASE 1; HEME OXYGENASE INHIBITOR; HEMIN; PHENETHYL ISOTHIOCYANATE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ZINC PROTOPORPHYRIN IX; ANTINEOPLASTIC AGENT; ISOTHIOCYANIC ACID DERIVATIVE; MESSENGER RNA;

APOPTOSIS; ARTICLE; CELL GROWTH; CELL PROLIFERATION; CELL SURVIVAL; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; GENE REPRESSION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; K562 CELL LINE; LEUKEMIA CELL; OXIDATIVE STRESS; PROTEIN EXPRESSION; PROTEIN SECRETION; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY;

ANTICARCINOGENIC AGENTS; APOPTOSIS; CASPASE 3; CASPASE 9; CASPASES; CELL PROLIFERATION; CYTOCHROMES C; HEME OXYGENASE-1; HUMANS; ISOTHIOCYANATES; K562 CELLS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; REACTIVE OXYGEN SPECIES; RNA, MESSENGER;

EID: 84901462769     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2167     Document Type: Article

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