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Volumn 49, Issue 5, 2014, Pages 853-863

xCT, component of cysteine/glutamate transporter, as an independent prognostic factor in human esophageal squamous cell carcinoma

Author keywords

Cell cycle; Esophageal cancer; xCT SLC7A11

Indexed keywords

AMINO ACID TRANSPORTER; CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN; SMALL INTERFERING RNA; TP53INP1 PROTEIN; TRANSCRIPTION FACTOR E2F5; UNCLASSIFIED DRUG; XCT; SLC7A11 PROTEIN, HUMAN;

EID: 84901453436     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-013-0847-5     Document Type: Article
Times cited : (37)

References (28)
  • 1
    • 0033597349 scopus 로고    scopus 로고
    • Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
    • Sato H, Tamba M, Ishii T, Bannai S. Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins. J Biol Chem. 1999;274:11455-8.
    • (1999) J Biol Chem , vol.274 , pp. 11455-11458
    • Sato, H.1    Tamba, M.2    Ishii, T.3    Bannai, S.4
  • 3
    • 42949126711 scopus 로고    scopus 로고
    • - cystine/glutamate antiporter: A potential target for therapy of cancer and other diseases
    • DOI 10.1002/jcp.21366
    • Lo M, Wang YZ, Gout PW. The x(c)- cystine/glutamate anti-porter: a potential target for therapy of cancer and other diseases. J Cell Physiol. 2008;215:593-602. (Pubitemid 351632680)
    • (2008) Journal of Cellular Physiology , vol.215 , Issue.3 , pp. 593-602
    • Lo, M.1    Wang, Y.-Z.2    Gout, P.W.3
  • 7
    • 0842311704 scopus 로고    scopus 로고
    • Suppression of Cystine Uptake by Sulfasalazine Inhibits Proliferation of Human Mammary Carcinoma Cells
    • Narang VS, Pauletti GM, Gout PW, Buckley DJ, Buckley AR. Suppression of cystine uptake by sulfasalazine inhibits proliferation of human mammary carcinoma cells. Anticancer Res. 2003;23:4571-9. (Pubitemid 38173869)
    • (2003) Anticancer Research , vol.23 , Issue.6 C , pp. 4571-4579
    • Narang, V.S.1    Pauletti, G.M.2    Gout, P.W.3    Buckley, D.J.4    Buckley, A.R.5
  • 10
    • 77953117152 scopus 로고    scopus 로고
    • Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer
    • Lo M, Ling V, Low C, Wang YZ, Gout PW. Potential use of the anti-inflammatory drug, sulfasalazine, for targeted therapy of pancreatic cancer. Curr Oncol. 2010;17:9-16.
    • (2010) Curr Oncol , vol.17 , pp. 9-16
    • Lo, M.1    Ling, V.2    Low, C.3    Wang, Y.Z.4    Gout, P.W.5
  • 11
    • 79952528125 scopus 로고    scopus 로고
    • CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth
    • Ishimoto T, Nagano O, Yae T, Tamada M, Motohara T, Oshima H, et al. CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. Cancer Cell. 2011;19:387-400.
    • (2011) Cancer Cell , vol.19 , pp. 387-400
    • Ishimoto, T.1    Nagano, O.2    Yae, T.3    Tamada, M.4    Motohara, T.5    Oshima, H.6
  • 12
    • 59149104276 scopus 로고    scopus 로고
    • Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway
    • Chen RS, Song YM, Zhou ZY, Tong T, Li Y, Fu M, et al. Disruption of xCT inhibits cancer cell metastasis via the caveolin-1/beta-catenin pathway. Oncogene. 2009;28:599-609.
    • (2009) Oncogene , vol.28 , pp. 599-609
    • Chen, R.S.1    Song, Y.M.2    Zhou, Z.Y.3    Tong, T.4    Li, Y.5    Fu, M.6
  • 13
    • 35148854098 scopus 로고    scopus 로고
    • Autocrine glutamate signaling promotes glioma cell invasion
    • DOI 10.1158/0008-5472.CAN-07-2034
    • Lyons SA, Chung WJ, Weaver AK, Ogunrinu T, Sontheimer H. Autocrine glutamate signaling promotes glioma cell invasion. Cancer Res. 2007;67:9463-71. (Pubitemid 47535936)
    • (2007) Cancer Research , vol.67 , Issue.19 , pp. 9463-9471
    • Lyons, S.A.1    Chung, W.J.2    Weaver, A.K.3    Ogunrinu, T.4    Sontheimer, H.5
  • 15
    • 0026543603 scopus 로고
    • Characterization of 21 newly established esophageal cancer cell lines
    • Shimada Y, Imamura M, Wagata T, Yamaguchi N, Tobe T. Characterization of 21 newly established esophageal cancer cell lines. Cancer. 1992;69:277-84.
    • (1992) Cancer , vol.69 , pp. 277-284
    • Shimada, Y.1    Imamura, M.2    Wagata, T.3    Yamaguchi, N.4    Tobe, T.5
  • 17
    • 0034772516 scopus 로고    scopus 로고
    • c cystine transporter: A new action for an old drug
    • DOI 10.1038/sj.leu.2402238
    • Gout PW, Buckley AR, Simms CR, Bruchovsky N. Sulfasalazine, a potent suppressor of lymphoma growth by inhibition of the x(c)- cystine transporter: a new action for an old drug. Leukemia. 2001;15:1633-40. (Pubitemid 32994684)
    • (2001) Leukemia , vol.15 , Issue.10 , pp. 1633-1640
    • Gout, P.W.1    Buckley, A.R.2    Simms, C.R.3    Bruchovsky, N.4
  • 18
    • 37549011780 scopus 로고    scopus 로고
    • xCT expression reduces the early cell cycle requirement for calcium signaling
    • Lastro M, Kourtidis A, Farley K, Conklin DS. xCT expression reduces the early cell cycle requirement for calcium signaling. Cell Signal. 2008;20:390-9.
    • (2008) Cell Signal , vol.20 , pp. 390-399
    • Lastro, M.1    Kourtidis, A.2    Farley, K.3    Conklin, D.S.4
  • 19
    • 55349095456 scopus 로고    scopus 로고
    • Cellular senescence: Molecular mechanisms, in vivo significance, and redox considerations
    • Muller M. Cellular senescence: molecular mechanisms, in vivo significance, and redox considerations. Antioxid Redox Signal. 2009;11:59-98.
    • (2009) Antioxid Redox Signal , vol.11 , pp. 59-98
    • Muller, M.1
  • 20
    • 0029910364 scopus 로고    scopus 로고
    • 1 checkpoint
    • Lukas J, Bartkova J, Bartek J. Convergence of mitogenic signalling cascades from diverse classes of receptors at the cyclin D-cyclin-dependent kinase-pRb-controlled G1 checkpoint. Mol Cell Biol. 1996;16:6917-25. (Pubitemid 26389751)
    • (1996) Molecular and Cellular Biology , vol.16 , Issue.12 , pp. 6917-6925
    • Lukas, J.1    Bartkova, J.2    Bartek, J.3
  • 21
    • 67650102336 scopus 로고    scopus 로고
    • Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma
    • Komatsu S, Imoto I, Tsuda H, Kozaki KI, Muramatsu T, Shimada Y, et al. Overexpression of SMYD2 relates to tumor cell proliferation and malignant outcome of esophageal squamous cell carcinoma. Carcinogenesis. 2009;30:1139-46.
    • (2009) Carcinogenesis , vol.30 , pp. 1139-1146
    • Komatsu, S.1    Imoto, I.2    Tsuda, H.3    Kozaki, K.I.4    Muramatsu, T.5    Shimada, Y.6
  • 22
    • 0036343646 scopus 로고    scopus 로고
    • Nuclear localization of the tight junction protein ZO-2 in epithelial cells
    • Islas S, Vega J, Ponce L, González-Mariscal L. Nuclear localization of the tight junction protein ZO-2 in epithelial cells. Exp Cell Res. 2002;274:138-48.
    • (2002) Exp Cell Res , vol.274 , pp. 138-148
    • Islas, S.1    Vega, J.2    Ponce, L.3    González-Mariscal, L.4
  • 25
    • 0023662316 scopus 로고
    • An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells
    • La Thangue NB, Rigby PW. An adenovirus E1A-like transcription factor is regulated during the differentiation of murine embryonal carcinoma stem cells. Cell. 1987;49:507-13.
    • (1987) Cell , vol.49 , pp. 507-513
    • La Thangue, N.B.1    Rigby, P.W.2
  • 26
    • 0032146274 scopus 로고    scopus 로고
    • The regulation of E2F by pRB-family proteins
    • Dyson N. The regulation of E2F by pRB-family proteins. Genes Dev. 1998;12:2245-62. (Pubitemid 28371346)
    • (1998) Genes and Development , vol.12 , Issue.15 , pp. 2245-2262
    • Dyson, N.1
  • 27
    • 61749099922 scopus 로고    scopus 로고
    • Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome
    • Umemura S, Shirane M, Takekoshi S, Kusakabe T, Itoh J, Egashira N, et al. Overexpression of E2F-5 correlates with a pathological basal phenotype and a worse clinical outcome. Br J Cancer. 2009;100:764-71.
    • (2009) Br J Cancer , vol.100 , pp. 764-771
    • Umemura, S.1    Shirane, M.2    Takekoshi, S.3    Kusakabe, T.4    Itoh, J.5    Egashira, N.6
  • 28
    • 78649704141 scopus 로고    scopus 로고
    • A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia
    • Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Study Group
    • Peters CJ, Rees JR, Hardwick RH, Hardwick JS, Vowler SL, Ong CA, Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Study Group, et al. A 4-gene signature predicts survival of patients with resected adenocarcinoma of the esophagus, junction, and gastric cardia. Gastroenterology. 2010;139(1995-2004):e15.
    • (2010) Gastroenterology , vol.139 , Issue.1995-2004
    • Peters, C.J.1    Rees, J.R.2    Hardwick, R.H.3    Hardwick, J.S.4    Vowler, S.L.5    Ong, C.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.