메뉴 건너뛰기




Volumn 123, Issue 21, 2014, Pages 3221-3229

Combinatorial effects of malaria season, iron deficiency, and inflammation determine plasma hepcidin concentration in African children

Author keywords

[No Author keywords available]

Indexed keywords

FERRITIN; HEPCIDIN; IRON;

EID: 84901443702     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2013-10-533000     Document Type: Article
Times cited : (57)

References (50)
  • 1
    • 77955027421 scopus 로고    scopus 로고
    • Estimating the global clinical burden of Plasmodium falciparum malaria in 2007
    • Hay SI, Okiro EA, Gething PW, et al. Estimating the global clinical burden of Plasmodium falciparum malaria in 2007. PLoS Med. 2010;7(6): e1000290.
    • (2010) PLoS Med. , vol.7 , Issue.6
    • Hay, S.I.1    Okiro, E.A.2    Gething, P.W.3
  • 2
    • 84897748468 scopus 로고    scopus 로고
    • Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: A systematic analysis for the global burden of disease study 2010
    • published correction appears in
    • Vos T, Flaxman AD, Naghavi M, et al. Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010 [published correction appears in Lancet. 2013;381(9867):628].
    • (2013) Lance , vol.381 , Issue.9867 , pp. 628
    • Vos, T.1    Flaxman, A.D.2    Naghavi, M.3
  • 3
    • 84871051576 scopus 로고    scopus 로고
    • Lancet. 2012;380(9859): 2163-2196
    • (2012) Lancet. , vol.380 , Issue.9859 , pp. 2163-2196
  • 4
    • 0035154276 scopus 로고    scopus 로고
    • A review of studies on the effect of iron deficiency on cognitive development in children
    • Grantham-McGregor S, Ani C. A review of studies on the effect of iron deficiency on cognitive development in children. J Nutr. 2001; 131(2, suppl 2):649S-666S.
    • (2001) J Nutr. , vol.131 , Issue.2 SUPPL. 2
    • Grantham-Mcgregor, S.1    Ani, C.2
  • 5
    • 30444459334 scopus 로고    scopus 로고
    • Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: Community-based, randomised, placebo-controlled trial
    • DOI 10.1016/S0140-6736(06)67962-2, PII S0140673606679622
    • Sazawal S, Black RE, Ramsan M, et al. Effects of routine prophylactic supplementation with iron and folic acid on admission to hospital and mortality in preschool children in a high malaria transmission setting: community-based, randomised, placebocontrolled trial. Lancet. 2006;367(9505):133-143. (Pubitemid 43077129)
    • (2006) Lancet , vol.367 , Issue.9505 , pp. 133-143
    • Sazawal, S.1    Black, R.E.2    Ramsan, M.3    Chwaya, H.M.4    Stoltzfus, R.J.5    Dutta, A.6    Dhingra, U.7    Kabole, I.8    Deb, S.9    Othman, M.K.10    Kabole, F.M.11
  • 6
    • 84879888176 scopus 로고    scopus 로고
    • Effect of provision of daily zinc and iron with several micronutrients on growth and morbidity among young children in Pakistan: A cluster-randomised trial
    • Soofi S, Cousens S, Iqbal SP, et al. Effect of provision of daily zinc and iron with several micronutrients on growth and morbidity among young children in Pakistan: a cluster-randomised trial. Lancet. 2013;382(9886):29-40.
    • (2013) Lancet. , vol.382 , Issue.9886 , pp. 29-40
    • Soofi, S.1    Cousens, S.2    Iqbal, S.P.3
  • 7
    • 84871913729 scopus 로고    scopus 로고
    • Implications of malaria on iron deficiency control strategies
    • Spottiswoode N, Fried M, Drakesmith H, Duffy PE. Implications of malaria on iron deficiency control strategies. Adv Nutr. 2012;3(4):570-578.
    • (2012) Adv Nutr. , vol.3 , Issue.4 , pp. 570-578
    • Spottiswoode, N.1    Fried, M.2    Drakesmith, H.3    Duffy, P.E.4
  • 8
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
    • DOI 10.1126/science.1104742
    • Nemeth E, Tuttle MS, Powelson J, et al. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science. 2004;306(5704):2090-2093. (Pubitemid 40007660)
    • (2004) Science , vol.306 , Issue.5704 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3    Vaughn, M.D.4    Donovan, A.5    Ward, D.M.6    Ganz, T.7    Kaplan, J.8
  • 9
    • 79955958017 scopus 로고    scopus 로고
    • Hepcidin and iron regulation, 10 years later
    • Ganz T. Hepcidin and iron regulation, 10 years later. Blood. 2011;117(17):4425-4433.
    • (2011) Blood. , vol.117 , Issue.17 , pp. 4425-4433
    • Ganz, T.1
  • 10
    • 0037111732 scopus 로고    scopus 로고
    • Inappropriate expression of hepcidin is associated with iron refractory anemia: Implications for the anemia of chronic disease
    • DOI 10.1182/blood-2002-04-1260
    • Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood. 2002;100(10):3776-3781. (Pubitemid 35303951)
    • (2002) Blood , vol.100 , Issue.10 , pp. 3776-3781
    • Weinstein, D.A.1    Roy, C.N.2    Fleming, M.D.3    Loda, M.F.4    Wolfsdorf, J.I.5    Andrews, N.C.6
  • 12
    • 70449387261 scopus 로고    scopus 로고
    • Plasmodium falciparum infected erythrocytes induce hepcidin (HAMP) mRNA synthesis by peripheral blood mononuclear cells
    • Armitage AE, Pinches R, Eddowes LA, Newbold CI, Drakesmith H. Plasmodium falciparum infected erythrocytes induce hepcidin (HAMP) mRNA synthesis by peripheral blood mononuclear cells. Br J Haematol. 2009;147(5): 769-771.
    • (2009) Br J Haematol. , vol.147 , Issue.5 , pp. 769-771
    • Armitage, A.E.1    Pinches, R.2    Eddowes, L.A.3    Newbold, C.I.4    Drakesmith, H.5
  • 14
    • 84879441627 scopus 로고    scopus 로고
    • Circulatory hepcidin is associated with the antiinflammatory response but not with iron or anemic status in childhood malaria
    • Burté F, Brown BJ, Orimadegun AE, et al. Circulatory hepcidin is associated with the antiinflammatory response but not with iron or anemic status in childhood malaria. Blood. 2013;121(15): 3016-3022.
    • (2013) Blood. , vol.121 , Issue.15 , pp. 3016-3022
    • Burté, F.1    Brown, B.J.2    Orimadegun, A.E.3
  • 15
    • 72349087245 scopus 로고    scopus 로고
    • Hepcidin and Plasmodium falciparum malaria in anemic school children in Mali [in French]
    • Ayoya MA, Stoltzfus RJ, Spiekermann-Brouwer GM, et al. Hepcidin and Plasmodium falciparum malaria in anemic school children in Mali [in French]. Bull Soc Pathol Exot. 2009;102(4): 219-220.
    • (2009) Bull Soc Pathol Exot. , vol.102 , Issue.4 , pp. 219-220
    • Ayoya, M.A.1    Stoltzfus, R.J.2    Spiekermann-Brouwer, G.M.3
  • 16
    • 58849136770 scopus 로고    scopus 로고
    • Assessment of urinary concentrations of hepcidin provides novel insight into disturbances in iron homeostasis during malarial infection
    • de Mast Q, Nadjm B, Reyburn H, et al. Assessment of urinary concentrations of hepcidin provides novel insight into disturbances in iron homeostasis during malarial infection. J Infect Dis. 2009;199(2):253-262.
    • (2009) J Infect Dis. , vol.199 , Issue.2 , pp. 253-262
    • De Mast, Q.1    Nadjm, B.2    Reyburn, H.3
  • 17
    • 84868556656 scopus 로고    scopus 로고
    • Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria
    • Casals-Pascual C, Huang H, Lakhal-Littleton S, et al. Hepcidin demonstrates a biphasic association with anemia in acute Plasmodium falciparum malaria. Haematologica. 2012;97(11): 1695-1698.
    • (2012) Haematologica. , vol.97 , Issue.11 , pp. 1695-1698
    • Casals-Pascual, C.1    Huang, H.2    Lakhal-Littleton, S.3
  • 18
    • 66149153847 scopus 로고    scopus 로고
    • Mild increases in serum hepcidin and interleukin-6 concentrations impair iron incorporation in haemoglobin during an experimental human malaria infection
    • de Mast Q, van Dongen-Lases EC, Swinkels DW, et al. Mild increases in serum hepcidin and interleukin-6 concentrations impair iron incorporation in haemoglobin during an experimental human malaria infection. Br J Haematol. 2009;145(5):657-664.
    • (2009) Br J Haematol. , vol.145 , Issue.5 , pp. 657-664
    • De Mast, Q.1    Van Dongen-Lases, E.C.2    Swinkels, D.W.3
  • 19
    • 77954503396 scopus 로고    scopus 로고
    • Increased serum hepcidin and alterations in blood iron parameters associated with asymptomatic P
    • de Mast Q, Syafruddin D, Keijmel S, et al. Increased serum hepcidin and alterations in blood iron parameters associated with asymptomatic P. falciparum and P. vivax malaria. Haematologica. 2010;95(7):1068-1074.
    • (2010) Falciparum and P. Vivax Malaria. Haematologica. , vol.95 , Issue.7 , pp. 1068-1074
    • De Mast, Q.1    Syafruddin, D.2    Keijmel, S.3
  • 20
    • 84857617139 scopus 로고    scopus 로고
    • Hepcidin is the major predictor of erythrocyte iron incorporation in anemic African children
    • Prentice AM, Doherty CP, Abrams SA, et al. Hepcidin is the major predictor of erythrocyte iron incorporation in anemic African children. Blood. 2012;119(8):1922-1928.
    • (2012) Blood. , vol.119 , Issue.8 , pp. 1922-1928
    • Prentice, A.M.1    Doherty, C.P.2    Abrams, S.A.3
  • 21
    • 78651272558 scopus 로고    scopus 로고
    • Afebrile Plasmodium falciparum parasitemia decreases absorption of fortification iron but does not affect systemic iron utilization: A double stable-isotope study in young Beninese women
    • Cercamondi CI, Egli IM, Ahouandjinou E, et al. Afebrile Plasmodium falciparum parasitemia decreases absorption of fortification iron but does not affect systemic iron utilization: a double stable-isotope study in young Beninese women. Am J Clin Nutr. 2010;92(6):1385-1392.
    • (2010) Am J Clin Nutr. , vol.92 , Issue.6 , pp. 1385-1392
    • Cercamondi, C.I.1    Egli, I.M.2    Ahouandjinou, E.3
  • 22
    • 47749099313 scopus 로고    scopus 로고
    • Iron incorporation and post-malaria anaemia
    • Doherty CP, Cox SE, Fulford AJ, et al. Iron incorporation and post-malaria anaemia. PLoS ONE. 2008;3(5):e2133.
    • (2008) PLoS ONE. , vol.3 , Issue.5
    • Doherty, C.P.1    Cox, S.E.2    Fulford, A.J.3
  • 23
    • 33744481007 scopus 로고    scopus 로고
    • Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype
    • Atkinson SH, Rockett K, Sirugo G, et al. Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotype. PLoS Med. 2006;3(5):e172.
    • (2006) PLoS Med. , vol.3 , Issue.5
    • Atkinson, S.H.1    Rockett, K.2    Sirugo, G.3
  • 24
    • 61849125779 scopus 로고    scopus 로고
    • Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children
    • Atkinson SH, Rockett KA, Morgan G, et al. Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children. Blood. 2008;112(10):4276-4283.
    • (2008) Blood. , vol.112 , Issue.10 , pp. 4276-4283
    • Atkinson, S.H.1    Rockett, K.A.2    Morgan, G.3
  • 25
    • 18944365782 scopus 로고    scopus 로고
    • Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya
    • DOI 10.1086/430006
    • Mwangi TW, Ross A, Snow RW, Marsh K. Case definitions of clinical malaria under different transmission conditions in Kilifi District, Kenya. J Infect Dis. 2005;191(11):1932-1939. (Pubitemid 40705402)
    • (2005) Journal of Infectious Diseases , vol.191 , Issue.11 , pp. 1932-1939
    • Mwangi, T.W.1    Ross, A.2    Snow, R.W.3    Marsh, K.4
  • 26
    • 0027308672 scopus 로고
    • Seasonal variation of paediatric diseases in the Gambia, West Africa
    • Brewster DR, Greenwood BM. Seasonal variation of paediatric diseases in The Gambia, west Africa. Ann Trop Paediatr. 1993;13(2):133-146. (Pubitemid 23193340)
    • (1993) Annals of Tropical Paediatrics , vol.13 , Issue.2 , pp. 133-146
    • Brewster, D.R.1    Greenwood, B.M.2
  • 28
    • 0034067118 scopus 로고    scopus 로고
    • Annual Plasmodium falciparum entomological inoculation rates (EIR) across Africa: Literature survey, Internet access and review
    • Hay SI, Rogers DJ, Toomer JF, Snow RW. Annual Plasmodium falciparum entomological inoculation rates (EIR) across Africa: literature survey, Internet access and review. Trans R Soc Trop Med Hyg. 2000;94(2):113-127.
    • (2000) Trans R Soc Trop Med Hyg. , vol.94 , Issue.2 , pp. 113-127
    • Hay, S.I.1    Rogers, D.J.2    Toomer, J.F.3    Snow, R.W.4
  • 29
    • 0028922489 scopus 로고
    • Relationships between Plasmodium falciparum transmission by vector populations and the incidence of severe disease at nine sites on the Kenyan coast
    • Mbogo CN, Snow RW, Khamala CP, et al. Relationships between Plasmodium falciparum transmission by vector populations and the incidence of severe disease at nine sites on the Kenyan coast. Am J Trop Med Hyg. 1995;52(3): 201-206.
    • (1995) Am J Trop Med Hyg. , vol.52 , Issue.3 , pp. 201-206
    • Mbogo, C.N.1    Snow, R.W.2    Khamala, C.P.3
  • 33
    • 0003492535 scopus 로고    scopus 로고
    • United Nations Children's Fund, United Nations University, World Health Organization (WHO) A Guide for Programme Managers. Geneva, Switzerland: WHO
    • United Nations Children's Fund, United Nations University, World Health Organization (WHO). Iron Deficiency Anaemia: Assessment, Prevention, and Control. A Guide for Programme Managers. Geneva, Switzerland: WHO; 2001.
    • (2001) Iron Deficiency Anaemia: Assessment, Prevention, and Control
  • 35
    • 0004110959 scopus 로고    scopus 로고
    • Using STATA's robust cluster command as appropriate
    • Armitage P, Berry G, Matthews JNS, eds. 4th ed. Oxford, United Kingdom: Blackwell Scientific Publications
    • Armitage P, Berry G, Matthews JNS. Using STATA's robust cluster command as appropriate. In: Armitage P, Berry G, Matthews JNS, eds. Statistical Methods in Medical Research. 4th ed. Oxford, United Kingdom: Blackwell Scientific Publications; 2001:378-454.
    • (2001) Statistical Methods in Medical Research , pp. 378-454
    • Armitage, P.1    Berry, G.2    Matthews, J.N.S.3
  • 38
    • 0032701717 scopus 로고    scopus 로고
    • Serum transferrin receptor levels are increased in asymptomatic and mild Plasmodium falciparum-infection
    • Mockenhaupt FP, May J, Stark K, Falusi AG, Meyer CG, Bienzle U. Serum transferrin receptor levels are increased in asymptomatic and mild Plasmodium falciparum-infection. Haematologica. 1999;84(10):869-873. (Pubitemid 29516915)
    • (1999) Haematologica , vol.84 , Issue.10 , pp. 869-873
    • Mockenhaupt, F.P.1    May, J.2    Stark, K.3    Falusi, A.G.4    Meyer, C.G.5    Bienzle, U.6
  • 39
    • 78751626577 scopus 로고    scopus 로고
    • Iron deficiency: Beyond anemia
    • Yadav D, Chandra J. Iron deficiency: beyond anemia. Indian J Pediatr. 2011;78(1):65-72.
    • (2011) Indian J Pediatr. , vol.78 , Issue.1 , pp. 65-72
    • Yadav, D.1    Chandra, J.2
  • 41
    • 80052587883 scopus 로고    scopus 로고
    • Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations
    • Traglia M, Girelli D, Biino G, et al. Association of HFE and TMPRSS6 genetic variants with iron and erythrocyte parameters is only in part dependent on serum hepcidin concentrations. J Med Genet. 2011;48(9):629-634.
    • (2011) J Med Genet. , vol.48 , Issue.9 , pp. 629-634
    • Traglia, M.1    Girelli, D.2    Biino, G.3
  • 42
    • 79959517566 scopus 로고    scopus 로고
    • Serum hepcidin: Reference ranges and biochemical correlates in the general population
    • Galesloot TE, Vermeulen SH, Geurts-Moespot AJ, et al. Serum hepcidin: reference ranges and biochemical correlates in the general population. Blood. 2011;117(25):e218-e225.
    • (2011) Blood. , vol.117 , Issue.25
    • Galesloot, T.E.1    Vermeulen, S.H.2    Geurts-Moespot, A.J.3
  • 43
    • 58149181388 scopus 로고    scopus 로고
    • An insight into the relationships between hepcidin, anemia, infections and inflammatory cytokines in pediatric refugees: A cross-sectional study
    • Cherian S, Forbes DA, Cook AG, et al. An insight into the relationships between hepcidin, anemia, infections and inflammatory cytokines in pediatric refugees: a cross-sectional study. PLoS ONE. 2008;3(12):e4030.
    • (2008) PLoS ONE. , vol.3 , Issue.12
    • Cherian, S.1    Forbes, D.A.2    Cook, A.G.3
  • 44
    • 84874050324 scopus 로고    scopus 로고
    • Serum hepcidin levels and iron parameters in children with iron deficiency
    • Choi HS, Song SH, Lee JH, Kim HJ, Yang HR. Serum hepcidin levels and iron parameters in children with iron deficiency. Korean J Hematol. 2012;47(4):286-292.
    • (2012) Korean J Hematol. , vol.47 , Issue.4 , pp. 286-292
    • Choi, H.S.1    Song, S.H.2    Lee, J.H.3    Kim, H.J.4    Yang, H.R.5
  • 45
    • 67149084949 scopus 로고    scopus 로고
    • Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: Diagnostic and therapeutic implications
    • Theurl I, Aigner E, Theurl M, et al. Regulation of iron homeostasis in anemia of chronic disease and iron deficiency anemia: diagnostic and therapeutic implications. Blood. 2009;113(21): 5277-5286.
    • (2009) Blood. , vol.113 , Issue.21 , pp. 5277-5286
    • Theurl, I.1    Aigner, E.2    Theurl, M.3
  • 46
    • 77957757423 scopus 로고    scopus 로고
    • Severe iron deficiency blunts the response of the iron regulatory gene Hamp and pro-inflammatory cytokines to lipopolysaccharide
    • Darshan D, Frazer DM, Wilkins SJ, Anderson GJ. Severe iron deficiency blunts the response of the iron regulatory gene Hamp and pro-inflammatory cytokines to lipopolysaccharide. Haematologica. 2010;95(10):1660-1667.
    • (2010) Haematologica. , vol.95 , Issue.10 , pp. 1660-1667
    • Darshan, D.1    Frazer, D.M.2    Wilkins, S.J.3    Anderson, G.J.4
  • 47
    • 65349173063 scopus 로고    scopus 로고
    • Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli
    • Huang H, Constante M, Layoun A, Santos MM. Contribution of STAT3 and SMAD4 pathways to the regulation of hepcidin by opposing stimuli. Blood. 2009;113(15):3593-3599.
    • (2009) Blood. , vol.113 , Issue.15 , pp. 3593-3599
    • Huang, H.1    Constante, M.2    Layoun, A.3    Santos, M.M.4
  • 48
    • 0004276682 scopus 로고    scopus 로고
    • 2nd ed. Cambridge, United Kingdom: Medical Research Council Dunn Nutrition Unit
    • McCrae JE, Paul AA. Foods of Rural Gambia. 2nd ed. Cambridge, United Kingdom: Medical Research Council Dunn Nutrition Unit; 1996.
    • (1996) Foods of Rural Gambia
    • McCrae, J.E.1    Paul, A.A.2
  • 49
    • 82455192819 scopus 로고    scopus 로고
    • Effect of supplementation with zinc and other micronutrients on malaria in Tanzanian children: A randomised trial
    • Veenemans J, Milligan P, Prentice AM, et al. Effect of supplementation with zinc and other micronutrients on malaria in Tanzanian children: a randomised trial. PLoS Med. 2011;8(11): e1001125.
    • (2011) PLoS Med. , vol.8 , Issue.11
    • Veenemans, J.1    Milligan, P.2    Prentice, A.M.3
  • 50
    • 84883390077 scopus 로고    scopus 로고
    • Iron fortification and malaria risk in children
    • Prentice AM, Verhoef H, Cerami C. Iron fortification and malaria risk in children. JAMA. 2013;310(9):914-915.
    • (2013) JAMA , vol.310 , Issue.9 , pp. 914-915
    • Prentice, A.M.1    Verhoef, H.2    Cerami, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.