메뉴 건너뛰기




Volumn 14, Issue 1, 2014, Pages

Early intervention in Alzheimer's disease: A health economic study of the effects of diagnostic timing

Author keywords

Alzheimer's disease; Cholinesterase inhibitors; Cost effectiveness; Dementia; Diagnosis; Early intervention; Health economics; Treatment

Indexed keywords

ALZHEIMER DISEASE; ARTICLE; COGNITION; COMPARATIVE STUDY; CONTROLLED STUDY; COST EFFECTIVENESS ANALYSIS; EARLY INTERVENTION; HEALTH CARE COST; HEALTH ECONOMICS; HUMAN; MAJOR CLINICAL STUDY; MENTAL DETERIORATION; MINI MENTAL STATE EXAMINATION; PALLIATIVE THERAPY; QUALITY ADJUSTED LIFE YEAR; AGE; COGNITION DISORDERS; COHORT ANALYSIS; COST BENEFIT ANALYSIS; ECONOMICS; LONGITUDINAL STUDY; NEUROPSYCHOLOGICAL TEST;

EID: 84901443680     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/1471-2377-14-101     Document Type: Article
Times cited : (140)

References (42)
  • 3
    • 79952730699 scopus 로고    scopus 로고
    • 2011 Alzheimer's disease facts and figures
    • Alzheimers Association
    • Alzheimers Association 2011 Alzheimer's disease facts and figures. Alzheimers Dement 2011, 7:208-244. Alzheimers Association.
    • (2011) Alzheimers Dement , vol.7 , pp. 208-244
  • 4
    • 84856008045 scopus 로고    scopus 로고
    • Mild cognitive impairment: disparity of incidence and prevalence estimates
    • 10.1016/j.jalz.2011.01.002, 22265588
    • Ward A, Arrighi HM, Michels S, Cedarbaum JM. Mild cognitive impairment: disparity of incidence and prevalence estimates. Alzheimers Dement 2012, 8:14-21. 10.1016/j.jalz.2011.01.002, 22265588.
    • (2012) Alzheimers Dement , vol.8 , pp. 14-21
    • Ward, A.1    Arrighi, H.M.2    Michels, S.3    Cedarbaum, J.M.4
  • 5
    • 0032988610 scopus 로고    scopus 로고
    • Mild Cognitive Impairment: Clinical Characterization and Outcome
    • 10.1001/archneur.56.3.303, 10190820
    • Petersen RC. Mild Cognitive Impairment: Clinical Characterization and Outcome. Arch Neurol 1999, 56:303-308. 10.1001/archneur.56.3.303, 10190820.
    • (1999) Arch Neurol , vol.56 , pp. 303-308
    • Petersen, R.C.1
  • 7
    • 79956084514 scopus 로고    scopus 로고
    • The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
    • 10.1016/j.jalz.2011.03.008, 3312027, 21514249
    • Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman DM, Jagust WJ, Petersen RC, Snyder PJ, Carrillo MC, Thies B, Phelps CH. The diagnosis of mild cognitive impairment due to Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement 2011, 7:270-279. 10.1016/j.jalz.2011.03.008, 3312027, 21514249.
    • (2011) Alzheimers Dement , vol.7 , pp. 270-279
    • Albert, M.S.1    DeKosky, S.T.2    Dickson, D.3    Dubois, B.4    Feldman, H.H.5    Fox, N.C.6    Gamst, A.7    Holtzman, D.M.8    Jagust, W.J.9    Petersen, R.C.10    Snyder, P.J.11    Carrillo, M.C.12    Thies, B.13    Phelps, C.H.14
  • 9
    • 0141738373 scopus 로고    scopus 로고
    • CSF markers for incipient Alzheimer's disease
    • 10.1016/S1474-4422(03)00530-1, 14505582
    • Blennow K, Hampel H. CSF markers for incipient Alzheimer's disease. Lancet Neurol 2003, 2:605-613. 10.1016/S1474-4422(03)00530-1, 14505582.
    • (2003) Lancet Neurol , vol.2 , pp. 605-613
    • Blennow, K.1    Hampel, H.2
  • 11
    • 77954028812 scopus 로고    scopus 로고
    • Enrichment through biomarkers in clinical trials of Alzheimer's drugs in patients with mild cognitive impairment
    • 1451.e1, 10.1016/j.neurobiolaging.2010.04.036, 20541287
    • Lorenzi M, Donohue M, Paternicò D, Scarpazza C, Ostrowitzki S, Blin O, Irving E, Frisoni GB. Enrichment through biomarkers in clinical trials of Alzheimer's drugs in patients with mild cognitive impairment. Neurobiol Aging 2010, 31:1443-1451. 1451.e1, 10.1016/j.neurobiolaging.2010.04.036, 20541287.
    • (2010) Neurobiol Aging , vol.31 , pp. 1443-1451
    • Lorenzi, M.1    Donohue, M.2    Paternicò, D.3    Scarpazza, C.4    Ostrowitzki, S.5    Blin, O.6    Irving, E.7    Frisoni, G.B.8
  • 13
    • 84901398131 scopus 로고    scopus 로고
    • The Brain Health Centre, powered by Ixico and Cambridge Cognition Ltd
    • The Brain Health Centre, powered by Ixico and Cambridge Cognition Ltd. http://www.thebrainhealthcentre.com/.
  • 14
    • 47849126559 scopus 로고    scopus 로고
    • Cost-effectiveness of drug therapies for Alzheimer's disease: A brief review
    • 2526383, 18830441
    • Geldmacher DS. Cost-effectiveness of drug therapies for Alzheimer's disease: A brief review. Neuropsychiatr Dis Treat 2008, 4:549-555. 2526383, 18830441.
    • (2008) Neuropsychiatr Dis Treat , vol.4 , pp. 549-555
    • Geldmacher, D.S.1
  • 15
    • 84856011523 scopus 로고    scopus 로고
    • An economic evaluation of early assessment for Alzheimer's disease in the United Kingdom
    • 10.1016/j.jalz.2010.07.001, 21420366
    • Getsios D, Blume S, Ishak KJ, Maclaine G, Hernández L. An economic evaluation of early assessment for Alzheimer's disease in the United Kingdom. Alzheimers Dement 2012, 8:22-30. 10.1016/j.jalz.2010.07.001, 21420366.
    • (2012) Alzheimers Dement , vol.8 , pp. 22-30
    • Getsios, D.1    Blume, S.2    Ishak, K.J.3    Maclaine, G.4    Hernández, L.5
  • 16
    • 67349195578 scopus 로고    scopus 로고
    • Early identification and treatment of Alzheimer's disease: social and fiscal outcomes
    • 10.1016/j.jalz.2009.01.028, 2785909, 19362885
    • Weimer DL, Sager MA. Early identification and treatment of Alzheimer's disease: social and fiscal outcomes. Alzheimers Dement 2009, 5:215-226. 10.1016/j.jalz.2009.01.028, 2785909, 19362885.
    • (2009) Alzheimers Dement , vol.5 , pp. 215-226
    • Weimer, D.L.1    Sager, M.A.2
  • 17
    • 84884891266 scopus 로고    scopus 로고
    • UK, London: Alzheimer's Society, Alzheimer's Society
    • Alzheimer's Society Mapping the Dementia Gap 2012, UK, London: Alzheimer's Society, Alzheimer's Society.
    • (2012) Mapping the Dementia Gap
  • 18
    • 75949093279 scopus 로고    scopus 로고
    • Missed and delayed diagnosis of dementia in primary care: prevalence and contributing factors
    • 10.1097/WAD.0b013e3181a6bebc, 2787842, 19568149
    • Bradford A, Kunik ME, Schulz P, Williams SP, Singh H. Missed and delayed diagnosis of dementia in primary care: prevalence and contributing factors. Alzheimer Dis Assoc Disord 2009, 23:306-314. 10.1097/WAD.0b013e3181a6bebc, 2787842, 19568149.
    • (2009) Alzheimer Dis Assoc Disord , vol.23 , pp. 306-314
    • Bradford, A.1    Kunik, M.E.2    Schulz, P.3    Williams, S.P.4    Singh, H.5
  • 20
    • 84887267473 scopus 로고    scopus 로고
    • Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis
    • 10.1503/cmaj.130451, 3826344, 24043661
    • Tricco AC, Soobiah C, Berliner S, Ho JM, Ng CH, Ashoor HM, Chen MH, Hemmelgarn B, Straus SE. Efficacy and safety of cognitive enhancers for patients with mild cognitive impairment: a systematic review and meta-analysis. CMAJ 2013, 185:1393-1401. 10.1503/cmaj.130451, 3826344, 24043661.
    • (2013) CMAJ , vol.185 , pp. 1393-1401
    • Tricco, A.C.1    Soobiah, C.2    Berliner, S.3    Ho, J.M.4    Ng, C.H.5    Ashoor, H.M.6    Chen, M.H.7    Hemmelgarn, B.8    Straus, S.E.9
  • 21
    • 84872111120 scopus 로고    scopus 로고
    • The economics of mild cognitive impairment
    • 10.1016/j.jalz.2012.05.2117, 23141385
    • Lin P-J, Neumann PJ. The economics of mild cognitive impairment. Alzheimers Dement 2013, 9:58-62. 10.1016/j.jalz.2012.05.2117, 23141385.
    • (2013) Alzheimers Dement , vol.9 , pp. 58-62
    • Lin, P.-J.1    Neumann, P.J.2
  • 22
    • 0037183483 scopus 로고    scopus 로고
    • Primary care expenditures before the onset of Alzheimer's disease
    • 10.1212/WNL.59.4.573, 12196651
    • Albert SM, Glied S, Andrews H, Stern Y, Mayeux R. Primary care expenditures before the onset of Alzheimer's disease. Neurology 2002, 59:573-578. 10.1212/WNL.59.4.573, 12196651.
    • (2002) Neurology , vol.59 , pp. 573-578
    • Albert, S.M.1    Glied, S.2    Andrews, H.3    Stern, Y.4    Mayeux, R.5
  • 23
    • 35848962080 scopus 로고    scopus 로고
    • Disease-modifying therapies for Alzheimer disease: challenges to early intervention
    • 10.1212/01.wnl.0000295996.54210.69, 17938373
    • Cummings JL, Doody R, Clark C. Disease-modifying therapies for Alzheimer disease: challenges to early intervention. Neurology 2007, 69:1622-1634. 10.1212/01.wnl.0000295996.54210.69, 17938373.
    • (2007) Neurology , vol.69 , pp. 1622-1634
    • Cummings, J.L.1    Doody, R.2    Clark, C.3
  • 25
    • 0035826771 scopus 로고    scopus 로고
    • Practice parameter: management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology
    • 10.1212/WNL.56.9.1154, 11342679
    • Doody RS, Stevens JC, Beck C, Dubinsky RM, Kaye JA, Gwyther L, Mohs RC, Thal LJ, Whitehouse PJ, DeKosky ST, Cummings JL. Practice parameter: management of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2001, 56:1154-1166. 10.1212/WNL.56.9.1154, 11342679.
    • (2001) Neurology , vol.56 , pp. 1154-1166
    • Doody, R.S.1    Stevens, J.C.2    Beck, C.3    Dubinsky, R.M.4    Kaye, J.A.5    Gwyther, L.6    Mohs, R.C.7    Thal, L.J.8    Whitehouse, P.J.9    DeKosky, S.T.10    Cummings, J.L.11
  • 26
    • 84885402153 scopus 로고    scopus 로고
    • Treatment for mild cognitive impairment: systematic review
    • 10.1192/bjp.bp.113.127811, 24085737
    • Cooper C, Li R, Lyketsos C, Livingston G. Treatment for mild cognitive impairment: systematic review. Br J Psychiatry 2013, 203:255-264. 10.1192/bjp.bp.113.127811, 24085737.
    • (2013) Br J Psychiatry , vol.203 , pp. 255-264
    • Cooper, C.1    Li, R.2    Lyketsos, C.3    Livingston, G.4
  • 29
    • 0016823810 scopus 로고
    • " Mini-mental state" . A practical method for grading the cognitive state of patients for the clinician
    • 10.1016/0022-3956(75)90026-6, 1202204
    • Folstein MF, Folstein SE, McHugh PR. " Mini-mental state" . A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975, 12:189-198. 10.1016/0022-3956(75)90026-6, 1202204.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 32
    • 33947592257 scopus 로고    scopus 로고
    • Long-term care and dementia services: an impending crisis
    • Macdonald A, Cooper B. Long-term care and dementia services: an impending crisis. Age Ageing 2007, 36:16-22.
    • (2007) Age Ageing , vol.36 , pp. 16-22
    • Macdonald, A.1    Cooper, B.2
  • 34
    • 84862645956 scopus 로고    scopus 로고
    • UK, London: Department of Health, Department of Health
    • Department of Health NHS Reference Costs: Financial Year 2011 to 2012 2012, UK, London: Department of Health, Department of Health.
    • (2012) NHS Reference Costs: Financial Year 2011 to 2012
  • 36
    • 84863994566 scopus 로고    scopus 로고
    • Office of National Statistics
    • Office of National Statistics Interim Life Tables, 2008-2010 2011, http://www.ons.gov.uk/ons/rel/lifetables/interim-life-tables/2008-2010/index.html, Office of National Statistics.
    • (2011) Interim Life Tables, 2008-2010
  • 37
    • 84871643821 scopus 로고    scopus 로고
    • Current and future treatments for Alzheimer's disease
    • 10.1177/1756285612461679, 3526946, 23277790
    • Yiannopoulou KG, Papageorgiou SG. Current and future treatments for Alzheimer's disease. Ther Adv Neurol Disord 2013, 6:19-33. 10.1177/1756285612461679, 3526946, 23277790.
    • (2013) Ther Adv Neurol Disord , vol.6 , pp. 19-33
    • Yiannopoulou, K.G.1    Papageorgiou, S.G.2
  • 38
    • 84874879020 scopus 로고    scopus 로고
    • Mortality and treatment costs have a great impact on the cost-effectiveness of disease modifying treatment in Alzheimer's disease-a simulation study
    • 10.2174/1567205011310020011, 23036018
    • Sköldunger A, Johnell K, Winblad B, Wimo A. Mortality and treatment costs have a great impact on the cost-effectiveness of disease modifying treatment in Alzheimer's disease-a simulation study. Curr Alzheimer Res 2013, 10:207-216. 10.2174/1567205011310020011, 23036018.
    • (2013) Curr Alzheimer Res , vol.10 , pp. 207-216
    • Sköldunger, A.1    Johnell, K.2    Winblad, B.3    Wimo, A.4
  • 39
    • 84898905802 scopus 로고    scopus 로고
    • Evaluation of full costs of care for patients with Alzheimer's disease in France: The predominant role of informal care
    • 10.1016/j.healthpol.2014.01.001, 24461717
    • Gervès C, Chauvin P, Bellanger MM. Evaluation of full costs of care for patients with Alzheimer's disease in France: The predominant role of informal care. Health Policy 2014, 116:114-122. 10.1016/j.healthpol.2014.01.001, 24461717.
    • (2014) Health Policy , vol.116 , pp. 114-122
    • Gervès, C.1    Chauvin, P.2    Bellanger, M.M.3
  • 40
    • 84873569844 scopus 로고    scopus 로고
    • The effects of dependence and function on costs of care for Alzheimer's disease and mild cognitive impairment in Ireland
    • 10.1002/gps.3819, 23386588
    • Gillespie P, O'Shea E, Cullinan J, Lacey L, Gallagher D, Ni Mhaolain A. The effects of dependence and function on costs of care for Alzheimer's disease and mild cognitive impairment in Ireland. Int J Geriatr Psychiatry 2013, 28:256-264. 10.1002/gps.3819, 23386588.
    • (2013) Int J Geriatr Psychiatry , vol.28 , pp. 256-264
    • Gillespie, P.1    O'Shea, E.2    Cullinan, J.3    Lacey, L.4    Gallagher, D.5    Ni Mhaolain, A.6
  • 41
    • 84880703597 scopus 로고    scopus 로고
    • A review of multidomain interventions to support healthy cognitive ageing
    • 10.1007/s12603-012-0402-8, 23459978
    • Schneider N, Yvon C. A review of multidomain interventions to support healthy cognitive ageing. J Nutr Health Aging 2013, 17:252-257. 10.1007/s12603-012-0402-8, 23459978.
    • (2013) J Nutr Health Aging , vol.17 , pp. 252-257
    • Schneider, N.1    Yvon, C.2
  • 42
    • 79956095382 scopus 로고    scopus 로고
    • Predictors of costs of care in Alzheimer's disease: a multinational sample of 1222 patients
    • 10.1016/j.jalz.2010.09.001, 21575872
    • Gustavsson A, Brinck P, Bergvall N, Kolasa K, Wimo A, Winblad B, Jönsson L. Predictors of costs of care in Alzheimer's disease: a multinational sample of 1222 patients. Alzheimers Dement 2011, 7:318-327. 10.1016/j.jalz.2010.09.001, 21575872.
    • (2011) Alzheimers Dement , vol.7 , pp. 318-327
    • Gustavsson, A.1    Brinck, P.2    Bergvall, N.3    Kolasa, K.4    Wimo, A.5    Winblad, B.6    Jönsson, L.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.