Molecular characterization of photosensitizer-mediated photodynamic therapy by gene expression profiling

Human and Experimental Toxicology

Volumn 33, Issue 6, 2014, Pages 629-637

  Liu, K H ^a   Wang, C P ^b   Chang, M F ^c   Chung, Y W ^c   Lou, P J ^b   Lin, J H ^d  

^a CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^c INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE   (Taiwan)

^d CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Cancer biology; chemopreventation; drug toxicology

Indexed keywords

AMINOLEVULINIC ACID; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 4; DISULFONATED ALUMINIUM PHTHALOCYANINE; DUAL SPECIFICITY PHOSPHATASE 6; EPHRIN B2; GROWTH DIFFERENTIATION FACTOR 15; INTERLEUKIN 8; LOW DENSITY LIPOPROTEIN RECEPTOR; MESO TETRAPHENYLPORPHYRIN DISULFONATE; PHOTOSENSITIZING AGENT; PHTHALOCYANINE DERIVATIVE; STROMELYSIN 2; SULFONIC ACID DERIVATIVE; TEMOPORFIN; TRANSCRIPTION FACTOR FOSB; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; APOPTOTIC PROTEASE ACTIVATING FACTOR 1 GENE; ARTICLE; CANCER CHEMOTHERAPY; CASPASE 4 GENE; CELL SURVIVAL; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG MECHANISM; DUAL SPECIFICITY PHOSPHATASE 6 GENE; EPHRIN B2 GENE; FOSB GENE; GENE; GENE EXPRESSION PROFILING; GROWTH DIFFERENTIATION FACTOR 15 GENE; HUMAN; HUMAN CELL; INTERLEUKIN 8 GENE; LOW DENSITY LIPOPROTEIN RECEPTOR GENE; MICROARRAY ANALYSIS; MOUTH SQUAMOUS CELL CARCINOMA; ONCOGENE C FOS; PHOTODYNAMIC THERAPY; PHOTOTOXICITY; PRIORITY JOURNAL; PROSTAGLANDIN ENDOPEROXIDE SYNTHASE 2 GENE; RAS HOMOLOG ENRICHED IN BRAIN LIKE 1 GENE; RETINOIC ACID INDUCED 3 GENE; SERPINB2 GENE; SIGNAL TRANSDUCTION; SQUAMOUS CELL CARCINOMA CELL LINE; STROMELYSIN 2 GENE; SURVIVAL RATE; DNA MICROARRAY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; HEAD AND NECK TUMOR; MOUTH TUMOR; PATHOLOGY; PHOTOCHEMOTHERAPY; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TIME; TUMOR CELL LINE;

CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL SURVIVAL; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; MOUTH NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; REAL-TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TIME FACTORS;

EID: 84901442544     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327113485257     Document Type: Article

References (21)

1. Fisher AM, Murphree AL, Gomer CJ. Clinical and preclinical photodynamic therapy. Lasers Surg Med. 1995 ; 17: 2-31
2. Ochsner M. Photophysical and photobiological processes in the photodynamic therapy of tumours. J Photochem Photobiol B: Biol. 1997 ; 39: 1-18 (Pubitemid 27285576)
3. Dougherty TJ, Gomer CJ, Henderson BW, Jori G, Kessel D, Korbelik M, et al. Photodynamic therapy. J Natl Cancer Inst. 1998 ; 90: 889-905 (Pubitemid 28304157)
4. Peng Q, Moan J, Nesland JM. Correlation of subcellular and intratumoral photosensitizer localization with ultrastructural features after photodynamic therapy. Ultrastruct Pathol. 1996 ; 20: 109-129 (Pubitemid 26117614)
5. Berg K, Western A, Bommer JC, Moan J. Intracellular localization of sulfonated meso-tetraphenylporphines in a human carcinoma cell line. Photochem Photobiol. 1990 ; 52: 481-487
6. Oleinick NL, Evans HH. The photobiology of photodynamic therapy: cellular targets and mechanisms. Radiat Res. 1998 ; 150: S146 - S156
7. Malik Z, Lugaci H. Destruction of erythroleukaemic cells by photoactivation of endogenous porphyrins. Br J Canc. 1987 ; 56: 589-595 (Pubitemid 17165652)
8. Melnokova VO, Bevdetnaya LN, Bour C, Festor E, Gramain MP, Merlin JL, et al. Subcellular localization of metatetra (hydrooxyphenyl) chlorin in human tumor cells subjected to photodynamic treatment. J Photochem Photobiol B: Biol. 1999 ; 49: 96-103 (Pubitemid 29267478)
9. Chen JY, Mak NK, Yow CMN, Fung MC, Chiu LC, Leung WN, et al. The binding characteristics and intracellular localization of Temoporfin (mTHPC) in myeloid leukemia cells: phototoxicity and mitochondrial damage. Photochem Photobiol. 2000 ; 72: 541-547
10. Noodt BB, Berg K, Stokke T, Peng Q, Nesland JM. Different apoptotic pathways are induced from various intracellular sites by tetraphenylporphyrins and light. Br J Canc. 1999 ; 79: 72-81 (Pubitemid 28566929)
11. Malham GM, Thomsen RJ, Finlay GJ, Baguley BC. Subcellular distribution and phototoxicity of aluminium phthalocyanines and haematoporphyrin derivative in cultured human meningioma cells. Br J Neurosurg. 1996 ; 10: 51-57 (Pubitemid 26079965)
12. Rezzoug H, Barberi-Heyob M, Merlin JL, Bolotine L, Lignon D, Guillemin F.. In vitro comparison of the photodynamic activity of meso-tetra- (hydroxyphenyl) chlorin and hematoporphyrin derivative. Bull Canc. 1996 ; 83: 816-822 (Pubitemid 26328837)
13. Margaron P, Sorrenti R, Levy JG. Photodynamic therapy inhibits cell adhesion without altering intergrin expression. Biochim Biophys Acta. 1997 ; 1359: 200-210 (Pubitemid 28027118)
14. Bonneau S, Morlière P, Brault D. Dynamics of interactions of photosensitizers with lipoproteins and membrane-models: correlation with cellular incorporation and subcellular distribution. Biochem Pharmacol. 2004 ; 68: 1443-1452 (Pubitemid 39179401)
15. Schena M, Shalon D, Heller R, Chai A, Brown PO, Davis RW. Parallel human genome analysis: micr-oarray-based expression monitoring of 1000 genes. Proc Natl Acad Sci USA. 1996 ; 93: 10614-10619 (Pubitemid 26333036)
16. Wulfkuhle J, Espina V, Liotta L, Petricoin E. Genomic and proteomic technologies for individualization and improvement of cancer treatment. Eur J Canc. 2004 ; 40: 2623-2632 (Pubitemid 39487084)
17. Wyld L, Reed MWR, Brown NJ. Differential cell death response to photodynamic therapy is dependent on dose and cell type. Br J Canc. 2001 ; 84: 1384-1386 (Pubitemid 32522108)
18. Kick G, Messer G, Plewig G, Kind P, Goetz AE. Strong and prolonged induction of c-jun and c-fos proto-oncogenes by photodynamic therapy. Br J Canc. 1996 ; 74: 30-36 (Pubitemid 26231974)
19. Themsche CV, Alain T, Kossakowska AE, Urbanski W, Potworowski EF, St-Pierre Y. Stromelysin-2 (matrix metalloproteinase 10) is inducible in lymphoma cells and accelerates the growth of lymphoid tumors in vivo. J Immunol. 2004 ; 173: 3605-3611 (Pubitemid 39280719)
20. Luna MC, Ferrario A, Rucker N, Gomer CJ. Decreased expression and function of alpha-2 macroglobulin receptor/low density lipoprotein receptor-related protein in photodynamic therapy-resistant mouse tumor cells. Canc Res. 1995 ; 155: 1820-1823
21. Wu Q, Ding W, Mirza A, Arsdale TV, Wei I, Bishop WR, et al. Integrative genomics revealed RAI3 is a cell growth-promoting gene and a novel P53 transcriptional target. J Biol Chem. 2005 ; 280: 12935-12943