Strong and prolonged induction of c-jun and c-fos proto-oncogenes by photodynamic therapy

British Journal of Cancer

Volumn 74, Issue 1, 1996, Pages 30-36

  Kick, G ^a   Messer, G ^a   Plewig, G ^a   Kind, P ^a   Goetz, A E ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF MUNICH   (Germany)

Author keywords

Oxidative stress; Photodynamic therapy; Photosensitisation; Proto oncogene

Indexed keywords

DNA BINDING PROTEIN; MESSENGER RNA; PHORBOL ESTER; PHOTOFRIN; PHOTOSENSITIZING AGENT; PYRROLIDINE DERIVATIVE; TRANSCRIPTION FACTOR AP 1;

ARTICLE; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; GENE INDUCTION; HELA CELL; HUMAN; HUMAN CELL; IMMEDIATE EARLY GENE; LASER; NORTHERN BLOTTING; ONCOGENE C FOS; ONCOGENE C JUN; PHOTODYNAMIC THERAPY; PHOTOSENSITIZATION; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTO ONCOGENE; RNA DEGRADATION; TRANSCRIPTION REGULATION;

EID: 0030037391     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.311     Document Type: Article

References (65)

1. ABATE C, PATEL L, RAUSCHER FJ AND CURRAN T. (1990). Redoxregulation of fos and jun DNA-binding activity in vitro. Science, 249, 1157-1161.
2. AMSTAD PA, KRUPITZA G AND CERUTTI PA. (1992). Mechanism of c-fos induction by active oxygen. Cancer Res., 52, 3952-3960.
3. ANGEL P AND KARIN M. (1991). The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation. Biochim. Biophys. Acta, 1072, 129-157.
4. ARUOMA OI, HALLIWELL B, HOEY BM AND BUTLER J. (1989). The antioxidant action of N-acetylcysteine: its reaction with hydrogen peroxide, hydroxyl radical, Superoxide, and hypochlorus acid. Free Radical Biol. Med., 6, 593-597.
5. BANNISTER AJ, COOK A AND KOUZARIDES T. (1991). In vitro DNA binding activity of Fos/Jun and BZLF1 but not C/EBP is affected by redox changes. Oncogene, 6, 1243-1250.
6. BOS TJ, MONTECLARO FS, MITSUNOBO F, BALL AR, CHANG CHW, NISHIMURA T AND VOGT PK. (1990). Efficient transformation of chicken embryo fibroblasts by c-jun requires structural modification in coding and noncoding sequences. Genes Dev., 4, 1677-1687.
7. BOYLE WJ, SMEAL T, DEFIZE LHK, ANGEL P, WOODGETT R, KARIN M AND HUNTER T. (1991). Activation of protein kinase C decreases phosphorylation of c-Jun at sites that negatively regulate its DNA binding activity. Cell, 64, 573-584.
8. BURGUNDER JM, VARRIALE A AND LAUTERBURG BH. (1989). Effect of N-acetylcysteine on plasma cysteine and glutathione following paracetamol administration. Eur. J. Clin. Pharmacol., 36, 127-131.
9. CHEN CA, YOU Y AND SHYU AB. (1992). Two cellular proteins bind specifically to a purine-rich sequence necessary for the destabilization function of a c-fos protein-coding region determinant of mRNA instability. Mol. Cell. Biol., 12, 5748-5757.
10. CHEN CY AND SHYU AB. (1994). Selective degradation of early-response gene mRNAs: functional analyses of sequence features of the AU-rich elements. Mol. Cell. Biol., 14, 8471-8482.
11. CHOMCZYNSKI P AND SACCHI N. (1987). Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem., 162, 156-159.
12. CRAWFORD D, ZBINDEN I, AMSTAD P AND CERUTTI PA. (1988). Oxidant stress induces the proto-oncogenes c-fos and c-myc in mouse epidermal cells. Oncogene, 3, 27-32.
13. CURRAN T AND FRANZA BR. (1988). Fos and Jun: the AP-1 connection. Cell, 55, 395-397.
14. DERIJARD B, HIBI M, WU IH, BARRETT T, SU B, DENG T, KARIN M AND DAVIS RJ. (1994). JNK1: A protein kinase stimulated by UV light and ha-ras that binds and phosphorylates the c-Jun activation domain. Cell, 76, 1025-1037.
15. DEVARY Y, GOTTLIEB RA, LAU LF AND KARIN M. (1991). Rapid and preferential activation of the c-jun gene during the mammalian UV-response. Mol. Cell. Biol., 11, 2804-2811.
16. EVANS S, MATTHEWS W, PERRY R, FRAKER D, NORTON J AND PASS HI. (1990). Effect of photodynamic therapy on tumor necrosis factor production by murine macrophages. J. Natl Cancer Inst., 82, 34-39.
17. FEINBERG AP AND VOGELSTEIN B. (1983). A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem., 132, 6-13.
18. FRAME MC, WILKIE NM, DARLING AJ, CHUDLEIGH A, PINTZAS A, LANG JC AND GILLESPIE DAF. (1991). Regulation of AP-1/DNA complex formation in vitro. Oncogene, 6, 205-209.
19. GENTZ R, RAUSCHER FJ, ABATE C AND CURRAN T. (1989). Parallel association of Fos and Jun leucine zippers juxtaposes DNA binding domains. Science, 243, 1695-1699.
20. GOLLNICK K. (1968). Type II photooxygenation reactions in solution. Adv. Photochem., 6, 1-122.
21. GOMER CJ, LUNA M, FERRARIO A AND RUCKER N. (1991). Increased transcription and translation of heme oxygenase in Chinese hamster fibroblasts following photodynamic stress of Photofrin II incubation. Photochem. Photobiol., 53, 275-279.
22. HAI T AND CURRAN T. (1991). Cross-family dimerization of transcription factors Fos/Jun and ATF/CREB alters DNA binding specificity. Proc. Natl Acad. Sci. USA, 88, 3720-3724.
23. HATTORI K, ANGEL P, LE BEAU MM AND KARIN M. (1988). Structure and chromosomal localization of the functional intronless human jun protooncogene. Proc. Natl Acad. Sci. USA, 85, 9148-9152.
24. HOLBROOK NJ AND FORNACE AJ. (1991). Response to adversity: molecular control of gene activation following genotoxic stress. New. Biol., 3, 825-833.
25. HSU W, KERPPOLA TK, CHEN PL, CURRAN T AND CHEN-KIANG S. (1994). Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper region. Mol. Cell. Biol., 14, 268-276.
26. HUNTER T AND KARIN M. (1992). The regulation of transcription by phosphorylation. Cell, 70, 375-387.
27. IVASHKIV LB, LIOU HC, KARA CJ, LAMPH WW, VERMA IM AND GLIMCHER LH. (1990). mXBP/CRE-BP2 and c-jun form a complex which binds to the cyclic AMP, but not to the 12-O-tetradecanoylphorbol-13-acetate, response element. Mol. Cell. Biol., 10, 1609-1621.
28. KABNICK KS AND HOUSMAN DE. (1988). Determinants that contribute to cytoplasmatic stability of human c-fos and β-globin mRNAs are located at several sites in each mRNA. Mol. Cell. Biol., 8, 3244-3250.
29. KALLUNKI T, SU B, TSIGELNY I, SLUSS HK, DERIJARD B, MOORE G, DAVIS R AND KARIN M. (1994). JNK2 contains a specificity-determining region responsible for efficient c-Jun binding and phosphorylation. Genes Dev., 8, 2996-3007.
30. KATAOKA K, IGARASHI K, ITOH K, FUJIWARA T, NODA M, YAMAMOTO M AND NISHIZAWA M. (1995). Small maf proteins heterodimerize with fos and may act as competitive repressors of the NF-E2 transcription factor. Mol. Cell. Biol., 15, 2180-2190.
31. KERPPOLA TK AND CURRAN T. (1993). Selective DNA binding by a variety of bZIP proteins. Mol. Cell. Biol., 13, 5479-5489.
32. KICK G, MESSER G, GOETZ A, PLEWIG G AND KIND P. (1995). Photodynamic therapy induces expression of interleukin 6 by activation of AP-1 but not NF-κB DNA binding. Cancer Res., 55, 2373-2379.
33. KIM R AND BECK WT. (1994). Differences between drug-sensitive and -resistant human leukemic CEM cells in c-jun expression, AP-1 DNA-binding activity, and formation of Jun/Fos family dimers, and their association with internucleosomal DNA ladders after treatment with VM-26. Cancer Res., 54, 4958-4966.
34. KOUZARIDES T AND ZIFF E. (1988). The role of the leucine zipper in the fos-jun interaction. Nature, 336, 646-651.
35. KYRIAKIS JM, BANERJEE P, NIKOLAKAKI E, DAL T, RUBIE EA, AHMAD MF, AVRUCH J AND WOODGETT JR. (1994). The stress-activated protein kinase subfamily of c-Jun kinases. Nature. 369, 156-160.
36. LANDSCHULZ WH, JOHNSON PF AND MCKNIGHT SL. (1988). The leucine zipper: a hypothetical structure common to a new class of DNA binding proteins. Science. 240, 1759-1764.
37. LEE WM, LIN C AND CURRAN T. (1988). Activation of the transforming potential of the human fos proto-oncogene requires message stabilization and results in increased amounts of partially modified fos protein. Mol. Cell. Biol., 8, 5521-5527.
38. LEUNIG A, STAUB F, PETERS J, HEIMANN A, CSAPO C, KEMPSKI O AND GOETZ AE (1994). Relation of early photofrin uptake to photodynamically induced phototoxicity and changes of cell volume in different cell lines. Eur. J. Cancer, 30, 78-83.
39. LI Y AND JAISWAL AK. (1994). Human antioxidant-response-element-mediated regulation of type 1 NAD(P)H:quinone oxidoreductase gene expression. Eur. J. Biochem., 226, 31-39.
40. LUNA MC, WONG S AND GOMER CJ. (1994). Photodynamic therapy mediated induction of early response genes. Cancer Res., 54, 1374-1380.
41. MANOME Y, DATTA R, TANEJA N, SHAFMAN T, BUMP E, HASS R, WEICHSELBAUM R AND KUFE D. (1993). Coinduction of c-jun gene expression and internucleosomal DNA fragmentation by ionizing irradiation. Biochemistry, 32, 10607-10613.
42. MEIJLINK F, CURRAN T, MILLER AD AND VERMA IM. (1985). Removing of a 67-basepair sequence in the noncoding region of protooncogene fos converts it to a transforming gene. Proc. Natl Acad. Sci. USA, 82, 4987-4991.
43. 2 and antioxidants have opposite effects on activation of NF-kappa B and AP-1 in intact cells: AP-1 as secondary antioxidant-responsive factor, EMBO J., 12, 2005-2015.
44. MILLER AD, CURRAN T AND VERMA IM. (1984). C-fos protein can induce cellular transformation: a novel mechanism of activation of a cellular oncogene. Cell, 36, 51-60.
45. MORGAN JI AND CURRAN T. (1991). Stimulus-transcription coupling in the nervous system: involvement of the inducible proto-oncogenes fos and jun. Annu. Rev. Neurosci., 14, 421-451.
46. NOSE K, SHIBANUMA M, KIKUCHI K, KAGEYAMA H, SAKIYAMA S AND KUROKI T. (1991). Transcriptional activation of early-response genes by hydrogen peroxide in a mouse osteoblastic cell line. Eur. J. Biochem., 201, 99-106.
47. PAPAVASSILIOU AG, BOHMANN K AND BOHMANN D. (1992). Determining the effect of inducible protein phosphorylation on the DNA-binding activity of transcription factors. Anal. Biochem., 203, 302-309.
48. PASS HI. (1993). Photodynamic therapy in oncology: mechanisms and clinical use. J. Natl Cancer Inst., 85, 443-456.
49. PLET A, EICK D AND BLANCHARD JM. (1995). Elongation and premature termination of transcripts initiated from c-fos and c-myc promoters show dissimilar patterns. Oncogene, 10, 319-328.
50. RAHMSDORF HJ, SCHÖNTHAL A, ANGEL P, LITFIN M, RÜTHER U AND HERRLICH P. (1987). Posttranslational regulation of c-fos mRNA expression. Nucleic Acids Res., 15, 1643-1659.
51. RÜTHER U, KOMITOWSKI D, SCHUBERT FR AND WAGNER EF. (1989). C-fos expression induces bone tumors in transgenic mice. Oncogene, 4, 861-865.
52. RYDER K, LANAHAN A AND PEREZ-ALBUERNE E. (1989). Jun D: a third member of the jun gene family. Proc. Natl Acad. Sci. USA, 86, 1500-1503.
53. RYTER SW, FERRARIO A, FISHER AM, EUNA M, RUCKER N, WONG S AND GOMER CJ (1991). Photooxidative stress and photodynamic therapy. In Oxidative Damage and Repair, Chemical, Biological and Medical Aspects, Davies KJA. (ed.) pp. 300-310. Pergamon: Oxford.
54. SAEZ E, RUTBERG SE, MUELLER E, OPPENHEIM H, SMOLUK J, YUSPA SH AND SPIEGELMAN BM. (1995). C-fos is required for malignant progression of skin tumors. Cell, 82, 721-732.
55. SASSONE-CORSI P, RANSONE LJ, LAMPH WW AND VERMA ID. (1988). Direct interaction between fos and jun nuclear oncoproteins: role of the 'leucine zipper' domain. Nature, 336, 692-695.
56. SCANLON KJ, ISHIDA H AND KASHANI-SABET M. (1994). Ribozyme-mediated reversal of the multidrug-resistant phenotype. Proc. Natl Acad. Sci. USA, 91, 11123-11127.
57. SCHENK H, KLEIN M, ERDBRÜGGER W, DRÖGE W AND SCHULZEOSTHOFF K. (1994). Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc. Natl Acad. Sci. USA, 91, 1672-1676.
58. SCHRECK R, MEIER B, MÄNNEL DN, DRÖGE W AND BAEUERLE PA. (1992). Dithiocarbamates as potent inhibitors of nuclear factor κB activation in intact cells. J. Exp. Med., 175, 1181-1194.
59. SHIBANUMA M, KUROKI T AND NOSE K. (1988). Induction of DNA replication and expression of proto-oncogene c-myc and c-foc in quiescent Balb/3T3 cells by xanthine/xanthine oxidase. Oncogene, 3, 17-21.
60. SHYU AB, GREENBERG ME AND BELASCO JG. (1989). The c-fos transcript is targeted for rapid decay by two distinct mRNA degradation pathways. Genes Dev., 3, 60-72.
61. SMEYNE RJ, VENDRELL M, HAYWARD M, BAKER SJ, MIAO GG, SCHILLING K, ROBERTSON LM, CURRAN T AND MORGAN JI. (1993). Continuous c-fos expression precedes programmed cell death in vivo. Nature, 363, 166-169.
62. TREISMAN R. (1986). Identification of a protein-binding site that mediates transcriptional response of the c-fos gene to serum factors. Cell, 46, 567-573.
63. VAN DEN BERG S, RAHMSDORE HJ, HERRLICH P AND KAINA B. (1993). Overexpression of c-fos increases recombination frequency in human osteosarcoma cells. Carcinogenesis, 14, 925-928.
64. WEISHAUPT KR, GOMER CJ AND DOUGHERTY T. (1976). Identification of singlet oxygen as the cytotoxic agent in photoinactivation of a murine tumor. Cancer Res., 36, 2326-2329.
65. XANTHOUDAKIS S, MIAO G, WANG F, PAN YCE AND CURRAN T. (1992). Redox activation of Fos Jun DNA binding activity is mediated by a DNA repair enzyme. EMBO J., 11, 3323-3335.