Rutin and quercetin show greater efficacy than nifedipin in ameliorating hemodynamic, redox, and metabolite imbalances in sodium chloride-induced hypertensive rats

Human and Experimental Toxicology

Volumn 33, Issue 6, 2014, Pages 602-608

  Olaleye, M T ^a   Crown, O O ^a   Akinmoladun, A C ^a   Akindahunsi, A A ^a  

^a Federal Univ of Technology   (Nigeria)

Author keywords

antihypertensive property; antioxidant; nifedipin; quercetin; Rutin; salt induced hypertension

Indexed keywords

CATALASE; CHOLESTEROL; CREATININE; GLUCOSE; GLUTATHIONE PEROXIDASE; LOW DENSITY LIPOPROTEIN; NIFEDIPINE; QUERCETIN; RUTOSIDE; SODIUM CHLORIDE; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UREA; ANTIHYPERTENSIVE AGENT; ANTIOXIDANT; BIOLOGICAL MARKER; SALT INTAKE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; COMPARATIVE EFFECTIVENESS; CONTROLLED STUDY; DIASTOLIC BLOOD PRESSURE; DIET SUPPLEMENTATION; DOSE RESPONSE; DRUG EFFICACY; ENZYME ACTIVITY; GLUCOSE BLOOD LEVEL; HEMODYNAMICS; HYPERTENSION; LIPID PEROXIDATION; MEAN ARTERIAL PRESSURE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PULSE PRESSURE; RAT; SYSTOLIC BLOOD PRESSURE; ANIMAL; ARTERIAL PRESSURE; BLOOD; CHEMICALLY INDUCED; COMPARATIVE STUDY; DISEASE MODEL; DRUG EFFECTS; OXIDATIVE STRESS; PATHOPHYSIOLOGY; SALT INTAKE; TIME; WISTAR RAT;

ANIMALS; ANTIHYPERTENSIVE AGENTS; ANTIOXIDANTS; ARTERIAL PRESSURE; BIOMARKERS; DISEASE MODELS, ANIMAL; HYPERTENSION; LIPID PEROXIDATION; NIFEDIPINE; OXIDATION-REDUCTION; OXIDATIVE STRESS; QUERCETIN; RATS, WISTAR; RUTIN; SODIUM CHLORIDE, DIETARY; TIME FACTORS;

EID: 84901434211     PISSN: 09603271     EISSN: 14770903     Source Type: Journal    
DOI: 10.1177/0960327113504790     Document Type: Article

References (44)

1. Cooper RS, Rotimi C. Establishing the epidemiologic basis for prevention of cardiovascular diseases in Africa. Ethn Dis. 1993 ; 3: S13 S22
2. Whelton PK. Epidemiology of hypertension. Lancet. 1994 ; 344: 101-106 (Pubitemid 24214139)
3. Chobanian AV, Bakris GL, Black HR, et al. Seventh report of the joint national committee on prevention, detection, evaluation, and treatment of high blood pressure. Hypertension. 2003 ; 42: 1206-1252 (Pubitemid 37553153)
4. Pasquale S, Lanfranco D, Ngianga-Bakwin K. Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies. BMJ. 2009 ; 339: b4567
5. Derlet RW, Horowitz BZ. Cardiotoxic drugs. Emerg Med Clin North Am. 1995 ; 13: 771-791
6. Mendelsohn R, Balick MJ. The value of undiscovered pharmaceuticals in tropical forests. Econ Bot. 1995 ; 49: 223-228
7. Bruneton J Pharmacognosie-phytochimie-plantes médicinales. 3 rd ed. Paris, France: Tec & Doc, 1999, p. 310. Paris, France: Tec & Doc ; 1999: 310.
8. Abeywardena MY, Head RJ. Dietary polyunsaturated fatty acid and antioxidant modulation of vascular dysfunction in the spontaneously hypertensive rat. Prostaglandins Leukot Essent Fatty Acids. 2001 ; 65: 91-99
9. Commission on Life Sciences. National Research Council. Guide for the Care and Use of Laboratory Animals. 1996 ;:
10. Adeboye JO, Fajonyomi MO, Makinde JM, et al. A preliminary study on the hypotensive activity of Persea americana leaf extracts in anaesthetized normotensive rats. Fitoterapia. 1999 ; 70: 15-20 (Pubitemid 29230099)
11. Ohkawa H, Ohishi H, Yagi K. Assay for lipid peroxide in animal tissues by thiobarbituric acid reaction. Anal Biochem. 1979 ; 95: 351-358 (Pubitemid 9194347)
12. Misra HP, Fridovich I. The role of superoxide anion in the autoxidation of epinephrine and simple assay for superoxide dismutase. J Biol Chem. 1972 ; 247: 3170-3175
13. Aebi H Methods of Enzymatic Analysis. Bergmeyer HU, ed. Weincheim, Germany: Chemie ; 1974: 673-677.
14. Chance B.. The iron-containing enzymes. The enzyme-substrate compounds and mechanism of action of the hydroperoxidases, chapter 56C. The Enzymes. 1951 ;: 428-453
15. Green LC, Wagner DA, Glogowski J, et al. Analysis of nitrate, nitrite and (15N) nitrite in biological fluids. Anal Biochem. 1982 ; 126: 131-138 (Pubitemid 13203451)
16. Meneton P, Jeunemaitre X, De Wardener HE, et al. Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases. Physiol Rev. 2005 ; 85: 679-715 (Pubitemid 40404639)
17. Duarte J, Perez-Palencia R, Vargas F, et al. Antihypertensive effects of the flavonoid quercetin in spontaneously hypertensive rats. Br J Pharmacol. 2001 ; 133: 117-124 (Pubitemid 32500458)
18. Duarte J, Jimenez R, O'Valle F, et al. Protective effects of the flavonoid quercetin in chronic nitric oxide deficient rats. J Hypertens. 2002 ; 20: 1843-1854
19. Bernatova I, Pechanova O, Babal P, et al. Wine polyphenols improve cardiovascular remodeling and vascular function in NO-deficient hypertension. Am J Physiol Heart Circ Physiol. 2002 ; 282: H942 - H948
20. Jalili T, Carlstrom J, Kim S, et al. Quercetin-supplemented diets lower blood pressure and attenuate cardiac hypertrophy in rats with aortic constriction. J Cardiovasc Pharmacol. 2006 ; 47: 531-541 (Pubitemid 44309671)
21. Hertog MG, Feskens EJ, Hallman PC, et al. Dietary antioxidant flavonoids and risk of coronary heart disease: the zutphen elderly study. Lancet. 1993 ; 342: 1007-1011 (Pubitemid 23314801)
22. Hertog MG, Hallman PC, Katan MB, et al. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands. Nutr Canc. 1993b ; 20: 21-29 (Pubitemid 23225364)
23. Knekt P, Kumpulainen J, Järvinen R. Flavonoid intake and risk of chronic diseases. Am J Clin Nutr. 2002 ; 76: 560-568 (Pubitemid 34920833)
24. Mennen LI, Sapinho D, de Bree A, et al. Consumption of foods. J Nutr. 2004 ; 134: 923-926
25. Manach C, Mazur A, Scalbert A. Polyphenols and prevention of cardiovascular diseases. Curr Opin Lipidol. 2005 ; 16: 77-84 (Pubitemid 40333370)
26. Andriambeloson E, Kleschyov AL, Muller B. Nitric oxide production and endothelium dependent vasorelaxation induced by wine polyphenols in rat aorta. Br J Pharmacol. 1997 ; 120: 1053-1058 (Pubitemid 27122644)
27. Burns J, Gardner PT, O'Neil J, et al. Relationship among antioxidant activity, vasidilation capacity and phenolic content of red wines. J Agic Food Chem. 2000 ; 48: 220-230 (Pubitemid 30120345)
28. Guyton AC, Hall JE. Textbook of Medical Physiology. 2000 ;: 793-844
29. Trolliet MR, Rudd MA, Loscalzo J. Oxidative stress andrenal dysfunction in salt-sensitive hypertension. Kidney Blood Press Res. 2001 ; 24: 116-123 (Pubitemid 32642065)
30. DelliPizzi A, Guan H, Tong X, et al. Lipoxygenase-dependent mechanisms in hypertension. Clin Exp Hypertens. 2000 ; 22: 181-192 (Pubitemid 30155434)
31. Zalba G, San Jose G, Moreno MU, et al. Oxidative stress in arterial hypertension: role of NAD(P)H oxidase. Hypertension. 2001 ; 38: 1395-1399 (Pubitemid 34033422)
32. Nickenig G, Harrison DG. The AT(1)-type angiotensin receptor in oxidative stress and atherogenesis: part I: oxidative stress and atherogenesis. Circulation. 2002 ; 105: 393-396 (Pubitemid 34106191)
33. Kitiyakara C, Chabrashvili T, Chen Y, et al. Salt intake, oxidative stress, and renal expression of NADPH oxidase and superoxide dismutase. J Am Soc Nephrol. 2003 ; 14: 2775-2782 (Pubitemid 37305640)
34. Bayorh MA, Ganafa AA, Socci RR, et al. The role of oxidative stress in salt-induced hypertension. Am J Hypertens. 2004 ; 17: 31 36
35. Vaziri ND, Ni Z, Oveisi F, et al. Effect of antioxidant therapy on blood pressure, and NO synthase expression in hypertensive rats. Hypertension. 2000 ; 36: 957-964
36. Taddei S, Virdis A, Ghiadoni L. Effect of calcium antagonist or beta blockade treatment on nitric oxide-dependent vasodilation and oxidative stress in essential hypertensive patients. J Hypertens. 2001 ; 19: 1379-1386 (Pubitemid 32730454)
37. Wasan KM, Najafi S, Wong J, et al. Assessing plasma lipid levels, body weight, and hepatic and renal toxicity following chronic oral administration of a water soluble phytostanol compound FMVP4, to gerbils. J Pharm Sci. 2001 ; 4: 228-234 (Pubitemid 34305598)
38. Luft FC. Molecular genetics of salt-sensitivity and hypertension. Drug Metab Dispos. 2001 ; 29: 500-504 (Pubitemid 32275524)
39. Gross JL, De Azevedo MJ, Silveiro SP, et al. Diabetic nephropathy: diagnosis, prevention, and treatment. Diabetes Care. 2005 ; 28: 164-176 (Pubitemid 40095801)
40. Beckman JA, Goldfine AB, Gordon MB, et al. Ascorbate restores endothelium-dependent vasodilation impaired by acute hyperglycemia in humans. Circulation. 2001 ; 103: 1618-1623 (Pubitemid 32246607)
41. Cervantes LD, Srinath P.. Rutin metabolites as powerful inhibitors of advanced glycation end products. FASEB J. 2008 ; 22 (614). 12
42. Brunzell JD. Consensus statement from the American diabetes association and the American college of cardiology foundation lipoprotein management in patients with cardiometabolic risk. Diabetes Care. 2008 ; 31: 811-822
43. Arai Y, Watanabe S, Kimira M, et al. Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration. J Nutr. 2000 ; 130: 2243-2250
44. Tojo A, Onozato L, Kobayashi N, et al. Angiotensin II and oxidative stress in Dahl salt-sensitive rat with heart failure. Hypertension. 2002 ; 40: 834-839 (Pubitemid 35434903)