Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter Niemann-Pick C1-Like 1 in Caco-2 cells and rats

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Nekohashi, Mari ^a   Ogawa, Mana ^a   Ogihara, Takuo ^b   Nakazawa, Kyoko ^c   Kato, Hisanori ^c   Misaka, Takumi ^a   Abe, Keiko ^a,d   Kobayashi, Shoko ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b TAKASAKI UNIVERSITY OF HEALTH AND WELFARE   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; CHOLESTEROL; EZETIMIBE; LUTEOLIN; MESSENGER RNA; NIEMANN PICK C1 LIKE 1 PROTEIN; QUERCETIN; UNCLASSIFIED DRUG; MEMBRANE PROTEIN; NPC1L1 PROTEIN, HUMAN; NPC1L1 PROTEIN, RAT;

ACTIVE TRANSPORT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHOLESTEROL BLOOD LEVEL; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; DRUG MECHANISM; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; IN VITRO STUDY; IN VIVO STUDY; INTESTINE ABSORPTION; MALE; NONHUMAN; PASSIVE TRANSPORT; PROTEIN EXPRESSION; RAT; ANIMAL; CACO 2 CELL LINE; DRUG EFFECTS; DRUG SCREENING; EPITHELIUM CELL; GENE EXPRESSION REGULATION; GENETICS; HEK293 CELL LINE; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CHOLESTEROL; DRUG EVALUATION, PRECLINICAL; EPITHELIAL CELLS; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; HYPERCHOLESTEROLEMIA; INTESTINAL ABSORPTION; LUTEOLIN; MALE; MEMBRANE PROTEINS; MEMBRANE TRANSPORT PROTEINS; QUERCETIN; RATS;

EID: 84901415997     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097901     Document Type: Article

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