Molecular evolution of GPCRs: 26Rfa/GPR103

Journal of Molecular Endocrinology

Volumn 52, Issue 3, 2014, Pages

  Ukena, Kazuyoshi ^a   Osugi, Tomohiro ^b,d   Leprince, Jérôme ^c   Vaudry, Hubert ^c   Tsutsui, Kazuyoshi ^b  

^a HIROSHIMA UNIVERSITY   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c UNIVERSITY OF ROUEN   (France)

^d SUNTORY INSTITUTE FOR BIOORGANIC RESEARCH   (Japan)

Author keywords

26RFa QRFP; Food intake; G protein coupled receptor; Hypothalamus; Neuropeptide

Indexed keywords

26RFA PROTEIN; AMINO ACID; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR 103; HYPOPHYSIS HORMONE; NEUROPEPTIDE; UNCLASSIFIED DRUG; ARGINYLPHENYLALANINAMIDE; OREXIN; PREPRO-26RFA PROTEIN, HUMAN; QRFPR PROTEIN, HUMAN; SIGNAL PEPTIDE;

BIRD; BLOOD PRESSURE; COMPARATIVE STUDY; FISH; FOOD INTAKE; HORMONE RELEASE; HUMAN; MAMMAL; NOCICEPTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OSSIFICATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; REVIEW; STEROIDOGENESIS; VERTEBRATE; AMINO ACID SEQUENCE; ANIMAL; BIOSYNTHESIS; BONE DEVELOPMENT; EATING; ENERGY METABOLISM; ENZYMOLOGY; GENETICS; HYPOTHALAMUS; MOLECULAR EVOLUTION; MOLECULAR GENETICS; NOCICEPTIVE PAIN; SEQUENCE ALIGNMENT;

AMINO ACID SEQUENCE; ANIMALS; BLOOD PRESSURE; BONE DEVELOPMENT; EATING; ENERGY METABOLISM; EVOLUTION, MOLECULAR; HUMANS; HYPOTHALAMUS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MOLECULAR SEQUENCE DATA; NEUROPEPTIDES; NOCICEPTIVE PAIN; OREXINS; RECEPTORS, G-PROTEIN-COUPLED; SEQUENCE ALIGNMENT;

EID: 84901412429     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-13-0207     Document Type: Review

References (56)

1. Alonzeau J., Alexandre D, Jeandel L, Courel M, Hautot C, El Yamani FZ, Gobet F., Leprince J, Magoul R, Amarti A et al. 2013 The neuropeptide 26RFa is expressed in human prostate cancer and stimulates the neuroendocrine differentiation and the migration of androgenoindependent prostate cancer cells. European Journal of Cancer 49 511-519. (doi:10.1016/j.ejca.2012.05.028)
2. Baribault H., Danao J, Gupte J, Yang L, Sun B, Richards W & Tian H 2006 The G-protein-coupled receptor GPR103 regulates bone formation. Molecular and Cellular Biology 26 709-717. (doi:10.1128/MCB.26.2.709-717.2006)
3. Bruzzone F., Lectez B, Tollemer H, Leprince J, Dujardin C, Rachidi W, Chatenet D., Baroncini M, Beauvillain JC, Vallarino M et al. 2006 Anatomical distribution and biochemical characterization of the novel RFamide peptide 26RFa in the human hypothalamus and spinal cord. Journal of Neurochemistry 99 616-627. (doi:10.1111/j.1471-4159.2006. 04090.x)
4. Bruzzone F., Lectez B, Alexandre D, Jégou S, Mounien L, Tollemer H, Chatenet D., Leprince J, Vallarino M, Vaudry H et al. 2007 Distribution of 26RFa binding sites and GPR103 mRNA in the central nervous system of the rat. Journal of Comparative Neurology 503 573-591. (doi:10.1002/cne.21400)
5. Chartrel N., Dujardin C, Anouar Y, Leprince J, Decker A, Clerens S, Do Régo J. C, Vandesande F, Llorens-Cortes C, Costentin J et al. 2003 Identification of 26RFa, a hypothalamic neuropeptide of the RFamide peptide family with orexigenic activity. PNAS 100 15247-15252. (doi:10.1073/pnas.2434676100)
6. Chartrel N., Dujardin C, Leprince J, Desrues L, Tonon MC, Cellier E, Cosette P., Jouenne T, Simonnet G & Vaudry H 2002 Isolation, characterization, and distribution of a novel neuropeptide, Rana RFamide (R-RFa), in the brain of the European green frog Rana esculenta. Journal of Comparative Neurology 448 111-127. (doi:10.1002/ cne.10253)
7. Chartrel N., Bruzzone F, Dujardin C, Leprince J, Tollemer H, Anouar Y, Vallarino M., Costentin J & Vaudry H 2005 Identification of 26RFa from frog brain: a novel hypothalamic neuropeptide with orexigenic activity in mammals. Annals of the New York Academy of Sciences 1040 80-83. (doi:10.1196/annals.1327.009)
8. Chartrel N., Tsutsui K, Costentin J & Vaudry H 2006a The RFamide-related peptides. In Handbook of Biologically Actives Peptides, pp 779-786.
9. Eds A. J Kastin. Amsterdam: Elsevier. Chartrel N., Bruzzone F, Leprince J, Tollemer H, Anouar Y, Do Régo JC, Ségalas-Milazzo I., Guilhaudis L, Cosette P, Jouenne T et al. 2006b Structure and functions of the novel hypothalamic RFamide neuropeptides R-RFa and 26RFa in vertebrates. Peptides 27 1110-1120. (doi:10.1016/j.peptides.2005.06.035)
10. Chartrel N., Alonzeau J, Alexandre D, Jeandel L, Alvear-Perez R, Leprince J, Boutin J., Vaudry H, Anouar Y & Llorens-Cortes C 2011 The RFamide neuropeptide 26RFa and its role in the control of neuroendocrine functions. Frontiers in Neuroendocrinology 32 387-397. (doi:10.1016/ j.yfrne.2011.04.001)
11. Do Régo J. C, Leprince J, Chartrel N, Vaudry H & Costentin J 2006 Behavioral effects of 26RFamide and related peptides. Peptides 27 2715-2721. (doi:10.1016/j.peptides.2006.04.017)
12. Egido E. M, Hernández R, Leprince J, Chartrel N, Vaudry H, Marco J & Silvestre R. A 2007 26RFa, a novel orexigenic neuropeptide, inhibits insulin secretion in the rat pancreas. Peptides 28 725-730. (doi:10.1016/ j.peptides.2006.04.004)
13. Frooninckx L., Van Rompay L, Temmerman L, Van Sinay E, Beets I, JanssenT, Husson S. J & Schoofs L 2012 Neuropeptide GPCRs in C. elegans. Frontiers in Endocrinology 3 167. (doi:10.3389/fendo.2012.00167)
14. Fukusumi S., Yoshida H, Fujii R, Murayama M, Komatsu H, Habata Y, Shintani Y., Hinuma S & Fujino M 2003 A new peptidic ligand and its receptor regulating adrenal function in rats. Journal of Biological Chemistry 278 46387-46395. (doi:10.1074/jbc.M305270200)
15. 35S]GTPgS binding. Neuropharmacology 52 376-386. (doi:10.1016/j.neuropharm.2006.07.034)
16. Grimmelikhuijzen C. J & Hauser F 2012 Mini-review: the evolution of neuropeptide signaling. Regulatory Peptides 177 S6-S9. (doi:10.1016/ j.regpep.2012.05.001)
17. Jiang Y., Luo L, Gustafson EL, Yadav D, Laverty M, Murgolo N, Vassileva G, Zeng M., Laz TM, Behan J et al. 2003 Identification and characterization of a novel RF-amide peptide ligand for orphan G-protein-coupled receptor SP9155. Journal of Biological Chemistry 278 27652-27657. (doi:10.1074/jbc.M302945200)
18. Kampe J., Wiedmer P, Pfluger PT, Castaneda TR, Burget L, Mondala H, Kerr J, Liaw C., Oldfield BJ, Tschöp MH et al. 2006 Effect of central administration of QRFP(26) peptide on energy balance and characterization of a second QRFP receptor in rat. Brain Research 1119 133-149. (doi:10.1016/j.brainres.2006.08.055)
19. Lectez B., Jeandel L, El-Yamani FZ, Arthaud S, Alexandre D, Mardargent A, Jégou S., Mounien L, Bizet P, Magoul R et al. 2009 The orexigenic activity of the hypothalamic neuropeptide 26RFa is mediated by the neuropeptide Y and proopiomelanocortin neurons of the arcuate nucleus. Endocrinology 150 2342-2350. (doi:10.1210/en.2008-1432)
20. Lee D. K, Nguyen T, Lynch KR, Cheng R, Vanti WB, Arkhitko O, Lewis T, Evans J. F, George SR & O'Dowd BF 2001 Discovery and mapping of ten novel G protein-coupled receptor genes. Gene 275 83-91. (doi:10.1016/ S0378-1119(01)00651-5)
21. Le Marec O., Neveu C, Lefranc B, Dubessy C, Boutin JA, Do-Régo JC, Costentin J., Tonon MC, Tena-Sempere M, Vaudry H et al. 2011 Structure-activity relationships of a series of analogues of the RFamiderelated peptide 26RFa. Journal of Medicinal Chemistry 54 4806-4814. (doi:10.1021/jm200418c)
22. Leprince J., Neveu C, Lefranc B, Guilhaudis L, Milazzo-Segalas I, Do Rego JC, Tena-Sempere M., Tsutsui K & Vaudry H 2013 26RFa. In Handbook of Biologically Active Peptides 2nd edn, pp 917-923. Ed A J Kastin. Amsterdam, The Netherlands: Elsevier.
23. Liu Y., Zhang Y, Li S, Huang W, Liu X, Lu D, Meng Z & Lin H 2009 Molecular cloning and functional characterization of the first nonmammalian 26RFa/QRFP orthologue in goldfish, Carassius auratus. Molecular and Cellular Endocrinology 303 82-90. (doi:10.1016/j.mce. 2009.01.009)
24. Malumba M., Jossart C, Granata R, Gallo D, Escher E, Ghigo E, Servant MJ, Marleau S. & Ong H 2010 GPR103b functions in the peripheral regulation of adipogenesis. Molecular Endocrinology 24 1615-1625. (doi:10.1210/me.2010-0010)
25. Mirabeau O. & Joly JS 2013 Molecular evolution of peptidergic signaling systems in bilaterians. PNAS 110 E2028-E2037. (doi:10.1073/pnas. 1219956110)
26. Moriya R., Sano H, Umeda T, Ito M, Takahashi Y, Matsuda M, Ishihara A, Kanatani A. & Iwaasa H 2006 RFamide peptide QRFP43 causes obesity with hyperphagia and reduced thermogenesis in mice. Endocrinology 147 2916-2922. (doi:10.1210/en.2005-1580)
27. Navarro V. M, Fernández-Fernández R, Nogueiras R, Vigo E, Tovar S, Chartrel N., Le Marec O, Leprince J, Aguilar E, Pinilla L et al. 2006 Novel role of 26RFa, a hypothalamic RFamide orexigenic peptide, as putative regulator of the gonadotropic axis. Journal of Physiology 573 237-249. (doi:10.1113/jphysiol.2006.106856)
28. Neveu C., Lefranc B, Tasseau O, Do Rego JC, Bourmaud A, Chan P, Bauchat P, Le Marec O., Chuquet J, Guilhaudis L et al. 2012 Rational design of a low molecular weight, stable, potent and long-lasting GPR103 aza-β3-pseudopeptide agonist. Journal of Medicinal Chemistry 55 7516-7524. (doi:10.1021/jm300507d)
29. Osugi T., Ukena K, Sower SA, Kawauchi H & Tsutsui K 2006 Evolutionary origin and divergence of PQRFamide peptides and LPXRFamide peptides in the RFamide peptide family. Insights from novel lamprey RFamide peptides. FEBS Journal 273 1731-1743. (doi:10.1111/j.1742-4658.2006.05187.x)
30. Panula P., Kalso E, Nieminen M, Kontinen VK, Brandt A & Pertovaara A 1999 Neuropeptide FF and modulation of pain. Brain Research 848 191-196. (doi:10.1016/S0006-8993(99)02044-2)
31. Patel S. R, Murphy KG, Thompson EL, Patterson M, Curtis AE, Ghatei MA & Bloom S. R 2008 Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats. Endocrinology 149 4747-4754. (doi:10.1210/en.2007-1562)
32. Price D. A & Greenberg MJ 1977 Structure of a molluscan cardioexcitatory neuropeptide. Science 197 670-671. (doi:10.1126/science.877582)
33. Primeaux S. D 2011 GRFP in female rats: effects on high fat food intake and hypothalamic gene expression across the estrous cycle. Peptides 32 1270-1275. (doi:10.1016/j.peptides.2011.03.022)
34. Primeaux S. D, Blackmon C, Barnes MJ, Braymer HD & Bray GA 2008 Central administration of the RFamide peptides, QRFP-26 and QRFP-43, increases high fat food intake in rats. Peptides 29 1994-2000. (doi:10. 1016/j.peptides.2008.07.024)
35. Primeaux S. D, Barnes MJ & Braymer HD 2013 Hypothalamic QRFP: regulation of food intake and fat selection. Hormone and Metabolic Research 45 967-974. (doi:10.1055/s-0033-1353181)
36. Qaiser F., Wahab F, Wigar MA, Hashim R, Leprince J, Vaudry H, Tena-Sempere M. & Shahab M 2012 Study of the role of novel RF-amide neuropeptides in affecting growth hormone secretion in a representative non-human primate (Macaca mulatta). Endocrine 42 658-663. (doi:10.1007/s12020-012-9672-5)
37. Raffa R. B 1988 The action of FMRFamide (Phe-Met-Arg-Phe-NH2) and related peptides on mammals. Peptides 9 915-922. (doi:10.1016/0196-9781(88)90141-6)
38. Ramanjaneya M., Karteris E, Chen J, Rucinski M, Ziolkowska A, Ahmed N, Kagerer S., Jöhren O, Lehnert H, Malendowicz LK et al. 2013 QRFP induces aldosterone production via PKC and T-type calcium channelmediated pathways in human adrenocortical cells: evidence for a novel role of GPR103. American Journal of Physiology. Endocrinology and Metabolism 305 E1049-E1058. (doi:10.1152/ajpendo.00191.2013)
39. Rastogi R. K, D'Aniello B, Pinelli C, Fiorentino M, Di Fiore MM, Di Meglio M & Iela L 2001 FMRFamide in the amphibian brain: a comprehensive survey. Microscopy Research and Technique 54 158-172. (doi:10.1002/ jemt.1130)
40. Roch G. J, Busby ER & Sherwood NM 2011 Evolution of GnRH: diving deeper. General and Comparative Endocrinology 171 1-16. (doi:10.1016/ j.ygcen.2010.12.014)
41. Sherwood N. M, Tello JA & Roch GJ 2006 Neuroendocrinology of protochordates: insights from Ciona genomics. Comparative Biochemistry and Physiology A 144 254-271. (doi:10.1016/j.cbpa. 2005.11.013)
42. Takayasu S., Sakurai T, Iwasaki S, Teranishi H, Yamanaka A, Williams SC, Iguchi H., Kawasawa YI, Ikeda Y, Sakakibara I et al. 2006 A neuropeptide ligand of the G protein-coupled receptor GPR103 regulates feeding, behavioral arousal, and blood pressure in mice. PNAS 103 7438-7443. (doi:10.1073/pnas.0602371103)
43. Tobari Y., Iijima N, Tsunekawa K, Osugi T, Haraguchi S, Ubuka T, Ukena K, Okanoya K., Tsutsui K & Ozawa H 2011 Identification, localisation and functional implication of 26RFa orthologue peptide in the brain of zebra finch (Taeniopygia guttata). Journal of Neuroendocrinology 23 791-803. (doi:10.1111/j.1365-2826.2011.02179.x)
44. Tsutsui K. 2009 A new key neurohormone controlling reproduction, gonadotropin-inhibitory hormone (GnIH): biosynthesis, mode of action and functional significance. Progress in Neurobiology 88 76-88. (doi:10.1016/j.pneurobio.2009.02.003)
45. Tsutsui K. & Ukena K 2006 Hypothalamic LPXRF-amide peptides in vertebrates: identification, localization and hypophysiotropic activity. Peptides 27 1121-1129. (doi:10.1016/j.peptides.2005.06.036)
46. Tsutsui K., Bentley GE, Bedecarrats G, Osugi T, Ubuka T & Kriegsfeld LJ 2010a Gonadotropin-inhibitory hormone (GnIH) and its control of central and peripheral reproductive function. Frontiers in Neuroendocrinology 31 284-295. (doi:10.1016/j.yfrne.2010.03.001)
47. Tsutsui K., Bentley GE, Kriegsfeld LJ, Osugi T, Seong JY & Vaudry H 2010b Discovery and evolutionary history of gonadotrophin-inhibitory hormone and kisspeptin: new key neuropeptides controlling reproduction. Journal of Neuroendocrinology 22 716-727. (doi:10.1111/ j.1365-2826.2010.02018.x)
48. Ukena K. & Tsutsui K 2005 A new member of the hypothalamic RF-amide peptide family, LPXRF-amide peptides: structure, localization, and function. Mass Spectrometry Reviews 24 469-486. (doi:10.1002/mas. 20031)
49. Ukena K., Tachibana T, Iwakoshi-Ukena E, Saito Y, Minakata H, Kawaguchi R., Osugi T, Tobari Y, Leprince J, Vaudry H et al. 2010 Identification, localization, and function of a novel avian hypothalamic neuropeptide, 26RFa, and its cognate receptor, Gprotein-coupled receptor-103. Endocrinology 151 2255-2264. (doi:10.1210/en.2009-1478)
50. Ukena K., Vaudry H, Leprince J & Tsutsui K 2011 Molecular evolution and functional characterization of the orexigenic peptide 26RFa and its receptor in vertebrates. Cell and Tissue Research 343 475-481. (doi:10.1007/s00441-010-1116-z) (doi:10.1007/s00441-010-1116-z)
51. Vallarino M., Salsotto-Cattaneo MT, Feuilloley M & Vaudry H 1991 Distribution of FMRFamide-like immunoreactivity in the brain of the elasmobranch fish Scyliorhinus canicula. Peptides 12 1321-1328. (doi:10. 1016/0196-9781(91)90214-A)
52. Vallarino M., Feuilloley M, D'Aniello B, Rastogi RK & Vaudry H 1994 Distribution of FMRFamide-like immunoreactivity in the brain of the lizard Podarcis sicula. Peptides 15 1057-1065. (doi:10.1016/0196-9781(94)90071-X)
53. Vallarino M., Feuilloley M, Thoumas JL, Demorgny R, Masini MA & Vaudry H. 1995 Distribution of FMRFamide-like immunoreactivity in the brain of the lungfish Protopterus annectens. Peptides 16 1187-1196. (doi:10.1016/0196-9781(95)02002-E)
54. Wahab F., Salahuddin H, Anees M, Leprince J, Vaudry H, Tena-SempereM& Shahab M. 2012 Study of the effect of 26RFand 43RF-amides on testosterone and prolactin secretion in the adult male rhesus monkey (Macaca mulatta). Peptides 36 23-28. (doi:10.1016/j.peptides. 2012.04.009)
55. Walker R. J, Papaioannou S & Holden-Dye L 2009 A review of FMRFamideand RFamide-like peptides in metazoa. Invertebrate Neuroscience 9 111-153. (doi:10.1007/s10158-010-0097-7)
56. Yamamoto T., Wada T & Miyazaki R 2008 Analgesic effects of intrathecally administered 26RFa, an intrinsic agonist for GPR103, on formalin test and carrageenan test in rats. Neuroscience 157 214-222. (doi:10.1016/ j.neuroscience.2008.08.061)