Involvement of Rac in thromboxane a2-induced human platelet activation: Regulation of sCD40 ligand release and PDGF-AB secretion

Molecular Medicine Reports

Volumn 10, Issue 1, 2014, Pages 107-112

  Kageyama, Yasunari ^a   Tomoaki, D O I ^a   Matsushima Nishiwaki, Rie ^a   Iida, Yuko ^a   Akamatsu, Shigeru ^b   Kondo, Akira ^a,c   Kuroyanagi, Gen ^a,c   Yamamoto, Naohiro ^a,c   Mizutani, Jun ^c   Otsuka, Takanobu ^c   Tokuda, Haruhiko ^a,d   Iida, Hiroki ^a   Kozawa, Osamu ^a   Ogura, Shinji ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b Matsunami General Hospital   (Japan)

^c NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

^d NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

Author keywords

P38 MAP kinase; PDGF AB; Rac; SCD40L

Indexed keywords

15 HYDROXY 11ALPHA,9ALPHA EPOXYMETHANOPROSTA 5,13 DIENOIC ACID; 4 AMINO 6 [2 [[4 (DIETHYLAMINO) 1 METHYLBUTYL]AMINO] 6 METHYL 4 PYRIMIDINYL] 2 METHYLQUINOLINE; CD40 LIGAND; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; PLATELET DERIVED GROWTH FACTOR AB; RAC PROTEIN; RISTOCETIN A; THROMBOXANE A2; AMINOQUINOLINE DERIVATIVE; PLATELET DERIVED GROWTH FACTOR; PLATELET-DERIVED GROWTH FACTOR AB; PYRIMIDINE DERIVATIVE; RISTOCETIN;

ARTICLE; CYTOKINE RELEASE; DOSE RESPONSE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; NORMAL HUMAN; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; THROMBOCYTE;

15-HYDROXY-11 ALPHA,9 ALPHA-(EPOXYMETHANO)PROSTA-5,13-DIENOIC ACID; AMINOQUINOLINES; BLOOD PLATELETS; CD40 LIGAND; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET-DERIVED GROWTH FACTOR; PYRIMIDINES; RAC GTP-BINDING PROTEINS; RISTOCETIN; THROMBOXANE A2;

EID: 84901396897     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2143     Document Type: Article

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