Drug metabolism enzymes in a steatotic model of rat treated with a high fat diet and a low dose of streptozotocin

Food and Chemical Toxicology

Volumn 70, Issue , 2014, Pages 54-60

  Vornoli, A ^a   Pozzo, L ^b   Della Croce, C M ^b   Gervasi, P G ^a   Longo, V ^b  

^a INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^b Institute of Agricultural Biology and Biotechnology   (Italy)

Author keywords

Cytochrome P450; High fat diet; Rat; Steatosis; Streptozotocin; Type 2 diabetes

Indexed keywords

CATALASE; CYTOCHROME P450 2C11; CYTOCHROME P450 2E1; CYTOCHROME P450 3A2; CYTOCHROME P450 4A; HEME OXYGENASE 1; STREPTOZOCIN; SUPEROXIDE DISMUTASE; TRANSCRIPTION FACTOR NRF2; CHOLESTEROL; GLUCOSE BLOOD LEVEL; HEME OXYGENASE; HMOX1 PROTEIN, RAT; NFE2L2 PROTEIN, RAT; NQO1 PROTEIN, RAT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; FATTY LIVER; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; LIPID DIET; LIPID PEROXIDATION; LIVER INJURY; MALE; NONHUMAN; OXIDATIVE STRESS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RAT; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; BLOOD; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; GLUCOSE BLOOD LEVEL; LIVER; METABOLISM; NON-ALCOHOLIC FATTY LIVER DISEASE; WISTAR RAT;

ANIMALS; BLOOD GLUCOSE; CHOLESTEROL; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP4A; DIET, HIGH-FAT; DOSE-RESPONSE RELATIONSHIP, DRUG; HEME OXYGENASE (DECYCLIZING); LIPID PEROXIDATION; LIVER; MALE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; NON-ALCOHOLIC FATTY LIVER DISEASE; OXIDATIVE STRESS; RATS; RATS, WISTAR; STREPTOZOCIN; TRIGLYCERIDES; UP-REGULATION;

EID: 84901388237     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2014.04.042     Document Type: Article

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