The role of muscle loading on bone (re)modeling at the developing enthesis

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Tatara, Alexander M ^a   Lipner, Justin H ^a   Das, Rosalina ^a   Kim, H Mike ^a   Patel, Nikunj ^a   Ntouvali, Eleni ^a   Silva, Matthew J ^a   Thomopoulos, Stavros ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACID PHOSPHATASE TARTRATE RESISTANT ISOENZYME; ALENDRONIC ACID; ALIZARIN; BOTULINUM TOXIN A; CALCEIN; ANTHRAQUINONE DERIVATIVE; BONE DENSITY CONSERVATION AGENT; FLUORESCEIN DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MASS; BONE MINERALIZATION; BONE REMODELING; BONE STRUCTURE; CONTROLLED STUDY; DOSE RESPONSE; ENCHONDRAL OSSIFICATION; ENTHESIS; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; MUSCLE LOADING; MUSCULOSKELETAL SYSTEM; MUSCULOSKELETAL SYSTEM PARAMETERS; NONHUMAN; OSSIFICATION; OSTEOCLAST; OSTEOLYSIS; PARALYSIS; ROTATOR CUFF; SHOULDER; TENDON; TRABECULAR BONE; ANIMAL; BONE DEVELOPMENT; CHEMICALLY INDUCED; DRUG EFFECTS; DRUG THERAPY; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; WEIGHT BEARING;

ALENDRONATE; ANIMALS; ANIMALS, NEWBORN; ANTHRAQUINONES; BONE DENSITY CONSERVATION AGENTS; BONE RESORPTION; BOTULINUM TOXINS, TYPE A; FLUORESCEINS; MICE; OSTEOCLASTS; OSTEOGENESIS; ROTATOR CUFF; WEIGHT-BEARING; X-RAY MICROTOMOGRAPHY;

EID: 84901380571     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097375     Document Type: Article

References (31)

1. Carter DR, van der Meulen MC, Beaupre GS (1998) Mechanobiologic regulation of osteogenesis and arthrogenesis. In: Buckwalter J, Ehrlich HP, Sandell LJ, Trippel SB, editors. Skeletal Growth and Development: Clinical Issues and Basic Science Advances. Rosemont, IL: AAOS. 99-130.
2. Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, et al. (2009) Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell 17: 861-873.
3. Sharir A, Stern T, Rot C, Shahar R, Zelzer E (2011) Muscle force regulates bone shaping for optimal load-bearing capacity during embryogenesis. Development 138: 3247-3259.
4. Nowlan NC, Murphy P, Prendergast PJ (2008) A dynamic pattern of mechanical stimulation promotes ossification in avian embryonic long bones. J Biomech 41: 249-258.
5. Thomopoulos S, Kim HM, Rothermich SY, Biederstadt C, Das R, et al. (2007) Decreased muscle loading delays maturation of the tendon enthesis during postnatal development. J Orthop Res 25: 1154-1163. (Pubitemid 47370837)
6. Kim HM, Galatz LM, Patel N, Das R, Thomopoulos S (2009) Recovery potential after postnatal shoulder paralysis. An animal model of neonatal brachial plexus palsy. J Bone Joint Surg Am 91: 879-891.
7. Kim HM, Galatz LM, Das R, Patel N, Thomopoulos S (2010) Musculoskeletal deformities secondary to neurotomy of the superior trunk of the brachial plexus in neonatal mice. J Orthop Res 28: 1391-1398.
8. Liu Y, Birman V, Chen C, Thomopoulos S, Genin GM (2011) Mechanisms of bimaterial attachment at the interface of tendon to bone. Journal of Engineering Materials and Technology 133: 281-288.
9. Liu YX, Thomopoulos S, Birman V, Li JS, Genin GM (2012) Bi-material attachment through a compliant interfacial system at the tendon-to-bone insertion site. Mechanics of Materials 44: 83-92.
10. Das R, Rich J, Kim HM, McAlinden A, Thomopoulos S (2011) Effects of botulinum toxin-induced paralysis on postnatal development of the supraspinatus muscle. J Orthop Res 29: 281-288.
11. Schwartz AG, Lipner JH, Pasteris JD, Genin GM, Thomopoulos S (2013) Muscle loading is necessary for the formation of a functional tendon enthesis. Bone 55: 44-51.
12. Mollberg M, Hagberg H, Bager B, Lilja H, Ladfors L (2005) High birthweight and shoulder dystocia: the strongest risk factors for obstetrical brachial plexus palsy in a Swedish population-based study. Acta Obstet Gynecol Scand 84: 654-659. (Pubitemid 40917389)
13. Kirkos JM, Kyrkos MJ, Kapetanos GA, Haritidis JH (2005) Brachial plexus palsy secondary to birth injuries. J Bone Joint Surg Br 87: 231-235. (Pubitemid 40278026)
14. Mehta SH, Blackwell SC, Bujold E, Sokol RJ (2006) What factors are associated with neonatal injury following shoulder dystocia? J Perinatol 26: 85-88.
15. Robling AG, Castillo AB, Turner CH (2006) Biomechanical and molecular regulation of bone remodeling. Annu Rev Biomed Eng 8: 455-498. (Pubitemid 44314825)
16. Evans KD, Lau ST, Oberbauer AM, Martin RB (2003) Alendronate affects long bone length and growth plate morphology in the oim mouse model for Osteogenesis Imperfecta. Bone 32: 268-274. (Pubitemid 36349530)
17. Kim HM, Galatz LM, Patel N, Das R, Thomopoulos S (2009) Recovery potential after postnatal shoulder paralysis. An animal model of neonatal brachial plexus palsy. The Journal of bone and joint surgery American volume 91: 879-891.
18. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, et al. (1987) Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2: 595-610.
19. Schwartz AG, Pasteris JD, Genin GM, Daulton TL, Thomopoulos S (2012) Mineral distributions at the developing tendon enthesis. PLoS One 7: e48630.
20. Wu Q, Zhang Y, Chen Q (2001) Indian hedgehog is an essential component of mechanotransduction complex to stimulate chondrocyte proliferation. J Biol Chem 276: 35290-35296.
21. Sato M, Grasser W (1990) Effects of bisphosphonates on isolated rat osteoclasts as examined by reflected light microscopy. J Bone Miner Res 5: 31-40. (Pubitemid 20089901)
22. Russell RG (2007) Bisphosphonates: mode of action and pharmacology. Pediatrics 119 Suppl 2: S150-162.
23. Halasy-Nagy JM, Rodan GA, Reszka AA (2001) Inhibition of bone resorption by alendronate and risedronate does not require osteoclast apoptosis. Bone 29: 553-559. (Pubitemid 33124298)
24. Weinstein RS, Roberson PK, Manolagas SC (2009) Giant osteoclast formation and long-term oral bisphosphonate therapy. The New England journal of medicine 360: 53-62.
25. Iwata K, Li J, Follet H, Phipps RJ, Burr DB (2006) Bisphosphonates suppress periosteal osteoblast activity independently of resorption in rat femur and tibia. Bone 39: 1053-1058. (Pubitemid 44528380)
26. Bikle DD, Morey-Holton ER, Doty SB, Currier PA, Tanner SJ, et al. (1994) Alendronate increases skeletal mass of growing rats during unloading by inhibiting resorption of calcified cartilage. Journal of bone and mineral research: the official journal of the American Society for Bone and Mineral Research 9: 1777-1787.
27. Plotkin LI, Weinstein RS, Parfitt AM, Roberson PK, Manolagas SC, et al. (1999) Prevention of osteocyte and osteoblast apoptosis by bisphosphonates and calcitonin. J Clin Invest 104: 1363-1374.
28. Plotkin LI, Lezcano V, Thostenson J, Weinstein RS, Manolagas SC, et al. (2008) Connexin 43 is required for the anti-apoptotic effect of bisphosphonates on osteocytes and osteoblasts in vivo. J Bone Miner Res 23: 1712-1721.
29. Bellido T, Plotkin LI (2011) Novel actions of bisphosphonates in bone: preservation of osteoblast and osteocyte viability. Bone 49: 50-55.
30. Boyce BF, Xing L (2008) Functions of RANKL/RANK/OPG in bone modeling and remodeling. Arch Biochem Biophys 473: 139-146.
31. Feng X, McDonald JM (2011) Disorders of bone remodeling. Annu Rev Pathol 6: 121-145.