Human motor neurons generated from neural stem cells delay clinical onset and prolong life in ALS mouse model

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Lee, Hong J ^a   Kim, Kwang S ^a   Ahn, Jin ^a   Bae, Hye M ^a   Lim, Inja ^a   Kim, Seung U ^a,b  

^a Chung Ang University   (South Korea)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE ACETYLTRANSFERASE; MICROTUBULE ASSOCIATED PROTEIN 2; NEUROFILAMENT PROTEIN; OLIGODENDROCYTE TRANSCRIPTION FACTOR 2; SONIC HEDGEHOG PROTEIN; DIFFERENTIATION ANTIGEN;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BEHAVIOR; CELL DIFFERENTIATION; CELL MIGRATION; CELL TRANSPLANTATION; CHAT GENE; CONTROLLED STUDY; FEMALE; FETUS; GENE; GENE EXPRESSION; GENETIC TRANSDUCTION; HB9 GENE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; ISL 1 GENE; LIFE EXTENSION; MOTONEURON; MOUSE; MOUSE MODEL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NEURAL STEM CELL; NEUROMUSCULAR SYNAPSE; NONHUMAN; OLIG2 GENE; SPINAL CORD VENTRAL HORN; SURVIVAL RATE; ANIMAL; CLINICAL TRIAL; GENETICS; MALE; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; TIME; TRANSFORMED CELL LINE; TRANSGENIC MOUSE; TRANSPLANTATION; XENOGRAFT;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIGENS, DIFFERENTIATION; CELL DIFFERENTIATION; CELL LINE, TRANSFORMED; FEMALE; HETEROGRAFTS; HUMANS; MALE; MICE; MICE, TRANSGENIC; MOTOR NEURONS; NEURAL STEM CELLS; TIME FACTORS;

EID: 84901371156     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0097518     Document Type: Article

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