Role of evolutionarily conserved signaling intermediate in Toll pathways (ECSIT) in the antibacterial immunity of Marsupenaeus japonicus

Developmental and Comparative Immunology

Volumn 46, Issue 2, 2014, Pages 246-254

  Ding, Ding ^a   Chen, Xiao Wei ^a   Kang, Li Hua ^a   Jiang, Hai Shan ^a   Kang, Cui Jie ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Anti lipopolysaccharide factor (ALF); ECSIT; Innate immunity; Shrimp; Toll Toll like receptor (TLR) signaling pathway

Indexed keywords

ADAPTOR PROTEIN; BONE MORPHOGENETIC PROTEIN; COMPLEMENTARY DNA; DOUBLE STRANDED DNA; EVOLUTIONARILY CONSERVED SIGNALING INTERMEDIATE IN TOLL PATHWAYS PROTEIN; PROTEIN MJECSIT 1; TOLL LIKE RECEPTOR; UNCLASSIFIED DRUG; ANTIMICROBIAL CATIONIC PEPTIDE; ARTHROPOD PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

ANIMAL TISSUE; ARTICLE; BASE PAIRING; BLOOD CELL; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE IDENTIFICATION; GENE SILENCING; GILL; HEART; HEPATOPANCREAS; IN VIVO STUDY; INNATE IMMUNITY; INTESTINE; LISTONELLA ANGUILLARUM; MARSUPENAEUS JAPONICUS; MJECSIT 1 GENE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; OVARY; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SHRIMP; SIGNAL TRANSDUCTION; STAPHYLOCOCCUS AUREUS; STOMACH; TESTIS; TRANSCRIPTION REGULATION; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; HOST PATHOGEN INTERACTION; IMMUNOLOGY; METABOLISM; MOLECULAR GENETICS; PENAEIDAE; PHYLOGENY; PHYSIOLOGY; VIBRIO;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; ANTIMICROBIAL CATIONIC PEPTIDES; ARTHROPOD PROTEINS; CONSERVED SEQUENCE; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; IMMUNITY, INNATE; MOLECULAR SEQUENCE DATA; ORGAN SPECIFICITY; PENAEIDAE; PHYLOGENY; TOLL-LIKE RECEPTORS; TRANSCRIPTION, GENETIC; VIBRIO;

EID: 84901353557     PISSN: 0145305X     EISSN: 18790089     Source Type: Journal    
DOI: 10.1016/j.dci.2014.04.016     Document Type: Article

References (41)

1. Akira S. Toll-like receptor signaling. J. Biol. Chem. 2003, 278:38105-38108.
2. Akira S., Uematsu S., Takeuchi O. Pathogen recognition and innate immunity. Cell 2006, 124:783-801.
3. Cuthbertson B.J., Deterding L.J., Williams J.G., Tomer K.B., Etienne K., Blackshear P.J., Bullesbach E.E., Gross P.S. Diversity in penaeidin antimicrobial peptide form and function. Dev. Comp. Immunol. 2008, 32:167-181.
4. de la Vega E., O'Leary N.A., Shockey J.E., Robalino J., Payne C., Browdy C.L., Warr G.W., Gross P.S. Anti-lipopolysaccharide factor in Litopenaeus vannamei (LvALF): a broad spectrum antimicrobial peptide essential for shrimp immunity against bacterial and fungal infection. Mol. Immunol. 2008, 45:1916-1925.
5. Ghosh S., May M.J., Kopp E.B. NF-κB and rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 1998, 16:225-260.
6. Hou F., He S., Liu Y., Zhu X., Sun C., Liu X. RNAi knock-down of shrimp Litopenaeus vannamei Toll gene and immune deficiency gene reveals their difference inregulating antimicrobial peptides transcription. Dev. Comp. Immunol. 2014, 44:255-260.
7. Imler J.L., Ferrandon D., Royet J., Reichhart J.M., Hetru C., Hoffmann J.A. Toll-dependent and Toll-independent immune responses in Drosophila. J. Endotoxin Res. 2004, 10:241-246.
8. Kang C.J., Xue J.F., Liu N., Zhao X.F., Wang J.X. Characterization and expression of a new subfamily member of penaeidin antimicrobial peptides (penaeidin 5) from Fenneropenaeus chinensis. Mol. Immunol. 2007, 44:1535-1543.
9. Kondo T., Watanabe M., Hatakeyama S. TRIM59 interacts with ECSIT and negatively regulates NF-kappaB and IRF-3/7-mediated signal pathways. Biochem. Biophys. Res. Commun. 2012, 422:501-507.
10. Kopp E., Medzhitov R., Carothers J., Xiao C., Douglas I., Janeway C.A., Ghosh S. ECSIT is an evolutionarily conserved intermediate in the Toll/IL-1 signal transduction pathway. Genes Dev. 1999, 13:2059-2071.
11. Lan J.F., Zhou J., Zhang X.W., Wang Z.H., Zhao X.F., Ren Q., Wang J.X. Characterization of an immune deficiency homolog (IMD) in shrimp (Fenneropenaeus chinensis) and crayfish (Procambarus clarkii). Dev. Comp. Immunol. 2013, 41:608-617.
12. Leung P., Tran L.T., Fast A.W. A logistic regression of risk factors for disease occurrence on Asian shrimp farms. Dis. Aquat. Organ 2000, 41:65-76.
13. Li F., Xiang J. Signaling pathways regulating innate immune responses in shrimp. Fish Shellfish Immunol. 2013, 34:973-980.
14. Lim K.H., Staudt L.M. Toll-like receptor signaling. Cold Spring Harb. Perspect. Biol. 2013, 5:a011247.
15. Liu H., Jiravanichpaisal P., Soderhall I., Cerenius L., Soderhall K. Antilipopolysaccharide factor interferes with white spot syndrome virus replication in vitro and in vivo in the crayfish Pacifastacus leniusculus. J. Virol. 2006, 80:10365-10371.
16. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 2001, 25:402-408.
17. Mattson M.P. An ECSIT-centric view of Alzheimer's disease. BioEssays 2012, 34:526-527.
18. Medzhitov R., Janeway C.A. Innate immunity: the virtues of a nonclonal system of recognition. Cell 1997, 91:295-298.
19. Milward E., Johnstone D., Trinder D., Ramm G., Olynyk J. The nexus of iron and inflammation in hepcidin regulation: SMADs, STATs, and ECSIT. Hepatology 2007, 45:253-256.
20. Moustakas A., Heldin C.H. Ecsit-ement on the crossroads of Toll and BMP signal transduction. Genes Dev. 2003, 17:2855-2859.
21. Muller U., Vogel P., Alber G., Schaub G.A. The innate immune system of mammals and insects. Contrib. Microbiol. 2008, 15:21-44.
22. Ponprateep S., Tharntada S., Somboonwiwat K., Tassanakajon A. Gene silencing reveals a crucial role for anti-lipopolysaccharide factors from Penaeus monodon in the protection against microbial infections. Fish Shellfish Immunol. 2012, 32:26-34.
23. Ren Q., Zhang Z., Li X.C., Jie D., Hui K.M., Zhang C.Y., Wang W. Three different anti-lipopolysaccharide factors identified from giant freshwater prawn, Macrobrachium rosenbergii. Fish Shellfish Immunol. 2012, 33:766-774.
24. Rosa R.D., Vergnes A., de Lorgeril J., Goncalves P., Perazzolo L.M., Saune L., Romestand B., Fievet J., Gueguen Y., Bachere E., Destoumieux-Garzon D. Functional divergence in shrimp anti-lipopolysaccharide factors (ALFs): from recognition of cell wall components to antimicrobial activity. PLoS One 2013, 8:e67937.
25. Smale S.T. Transcriptional regulation in the innate immune system. Curr. Opin. Immunol. 2012, 24:51-57.
26. Smith V.J., Fernandes J.M., Kemp G.D., Hauton C. Crustins: enigmatic WAP domain-containing antibacterial proteins from crustaceans. Dev. Comp. Immunol. 2008, 32:758-772.
27. Soler-Lopez M., Badiola N., Zanzoni A., Aloy P. Towards Alzheimer's root cause: ECSIT as an integrating hub between oxidative stress, inflammation and mitochondrial dysfunction. Hypothetical role of the adapter protein ECSIT in familial and sporadic Alzheimer's disease pathogenesis. BioEssays 2012, 34:532-541.
28. Somboonwiwat K., Marcos M., Tassanakajon A., Klinbunga S., Aumelas A., Romestand B., Gueguen Y., Boze H., Moulin G., Bachere E. Recombinant expression and anti-microbial activity of anti-lipopolysaccharide factor (ALF) from the black tiger shrimp Penaeus monodon. Dev. Comp. Immunol. 2005, 29:841-851.
29. Sun C., Du X.J., Xu W.T., Zhang H.W., Zhao X.F., Wang J.X. Molecular cloning and characterization of three crustins from the Chinese white shrimp, Fenneropenaeus chinensis. Fish Shellfish Immunol. 2010, 28:517-524.
30. Tamura K., Peterson D., Peterson N., Stecher G., Nei M., Kumar S. MEGA5: molecular evolutionary genetics analysis using maximum likelihood, evolutionary distance, and maximum parsimony methods. Mol. Biol. Evol. 2011, 28:2731-2739.
31. Tanaka S., Nakamura T., Morita T., Iwanaga S. Limulus anti-LPS factor: an anticoagulant which inhibits the endotoxin mediated activation of Limulus coagulation system. Biochem. Biophys. Res. Commun. 1982, 105:717-723.
32. Tassanakajon A., Somboonwiwat K., Supungul P., Tang S. Discovery of immune molecules and their crucial functions in shrimp immunity. Fish Shellfish Immunol. 2013, 34:954-967.
33. Tharntada S., Somboonwiwat K., Rimphanitchayakit V., Tassanakajon A. Anti-lipopolysaccharide factors from the black tiger shrimp, Penaeus monodon, are encoded by two genomic loci. Fish Shellfish Immunol. 2008, 24:46-54.
34. Valanne S., Wang J.H., Ramet M. The Drosophila Toll signaling pathway. J. Immunol. 2011, 186:649-656.
35. Vogel R.O., Janssen R.J., van den Brand M.A., Dieteren C.E., Verkaart S., Koopman W.J., Willems P.H., Pluk W., van den Heuvel L.P., Smeitink J.A., Nijtmans L.G. Cytosolic signaling protein Ecsit also localizes to mitochondria where it interacts with chaperone NDUFAF1 and functions in complex I assembly. Genes Dev. 2007, 21:615-624.
36. Wang X.W., Wang J.X. Pattern recognition receptors acting in innate immune system of shrimp against pathogen infections. Fish Shellfish Immunol. 2013, 34:981-989.
37. Wang P.H., Liang J.P., Gu Z.H., Wan D.H., Weng S.P., Yu X.Q., He J.G. Molecular cloning, characterization and expression analysis of two novel Tolls (LvToll2 and LvToll3) and three putative Spatzle-like Toll ligands (LvSpz1-3) from Litopenaeus vannamei. Dev. Comp. Immunol. 2012, 36:359-371.
38. Wang P.H., Gu Z.H., Wan D.H., Liu B.D., Huang X.D., Weng S.P., Yu X.Q., He J.G. The shrimp IKK-NF-kappaB signaling pathway regulates antimicrobial peptide expression and may be subverted by white spot syndrome virus to facilitate viral gene expression. Cell. Mol. Immunol. 2013, 10:423-436.
39. West A.P., Brodsky I.E., Rahner C., Woo D.K., Erdjument-Bromage H., Tempst P., Walsh M.C., Choi Y., Shadel G.S., Ghosh S. TLR signalling augments macrophage bactericidal activity through mitochondrial ROS. Nature 2011, 472:476-480.
40. Xiao C., Shim J.H., Kluppel M., Zhang S.S., Dong C., Flavell R.A., Fu X.Y., Wrana J.L., Hogan B.L., Ghosh S. Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes Dev. 2003, 17:2933-2949.
41. Zhang L., Li L., Zhang G. The first identification of molluscan Ecsit in the Pacific oyster, Crassostrea gigas, and its expression against bacterial challenge. Aquac. Res. 2012, 43:1071-1080.