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Volumn 42, Issue 6, 2014, Pages 1423-1432

Impact of therapeutic strategies on the prognosis of Candidemia in the ICU

Author keywords

Antifungal agents; candidiasis; epidemiology; intensive care units; mortality; treatment outcome

Indexed keywords

AMPHOTERICIN B; ANIDULAFUNGIN; CASPOFUNGIN; ECHINOCANDIN; FLUCONAZOLE; MICAFUNGIN; PYRROLE;

EID: 84901313627     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000221     Document Type: Article
Times cited : (127)

References (46)
  • 1
    • 72249087115 scopus 로고    scopus 로고
    • EPIC II Group of Investigators: International study of the prevalence and outcomes of infection in intens ive care units
    • Vincent JL,Rello J,Marshall J,et al, EPIC II Group of Investigators: International study of the prevalence and outcomes of infection in intens ive care units. JAMA,2009,302, 2323-2329.
    • (2009) JAMA , vol.302 , pp. 2323-2329
    • Vincent, J.L.1    Rello, J.2    Marshall, J.3
  • 2
    • 34249339733 scopus 로고    scopus 로고
    • European surveillance of ICU-acquired infections (HELICS-ICU): Methods and main results
    • Suetens C, Morales I, Savey A, et al: European surveillance of ICU-acquired infections (HELICS-ICU): Methods and main results. J Hosp Infect 2007; 65(Suppl 2):171-173
    • (2007) J Hosp Infect , vol.65 , Issue.SUPPL. 2 , pp. 171-173
    • Suetens, C.1    Morales, I.2    Savey, A.3
  • 3
    • 84878823678 scopus 로고    scopus 로고
    • Epidemiology of invasive fungal infections in the intensive care unit: Results of a multicenter Italian survey (AURORA Project)
    • Montagna MT, Caggiano G, Lovero G, et al: Epidemiology of invasive fungal infections in the intensive care unit: Results of a multicenter Italian survey (AURORA Project). Infec tion 2013; 41:645-653
    • (2013) Infec Tion , vol.41 , pp. 645-653
    • Montagna, M.T.1    Caggiano, G.2    Lovero, G.3
  • 4
    • 3943093972 scopus 로고    scopus 로고
    • Nosocomial bloodstream infections in US hospitals: Analysis of 24,179 cases from a prospective nationwide surveillance study
    • Wisplinghoff H, Bischoff T, Tallent SM, et al: Nosocomial bloodstream infections in US hospitals: Analysis of 24,179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004; 39:309-317
    • (2004) Clin Infect Dis , vol.39 , pp. 309-317
    • Wisplinghoff, H.1    Bischoff, T.2    Tallent, S.M.3
  • 5
    • 79953181947 scopus 로고    scopus 로고
    • Extended prevalence of infection in icu study (epic ii) group of investigators: Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of in fection in intensive care unit study
    • Kett DH, Azoulay E, Echeverria PM, et al; Extended Prevalence of Infection in ICU Study (EPIC II) Group of Investigators: Candida bloodstream infections in intensive care units: Analysis of the extended prevalence of in fection in intensive care unit study. Crit Care Med 2011; 39:665-670
    • (2011) Crit Care Med , vol.39 , pp. 665-670
    • Kett, D.H.1    Azoulay, E.2    Echeverria, P.M.3
  • 6
    • 69049100062 scopus 로고    scopus 로고
    • Australian candidaemia study: Determinants of mortality in non-neutropenic ICU patients with candidaemia
    • Marriott DJ, Playford EG, Chen S, et al; Australian Candidaemia Study: Determinants of mortality in non-neutropenic ICU patients with candidaemia. Crit Care 2009; 13:R115
    • (2009) Crit Care , vol.13
    • Marriott, D.J.1    Playford, E.G.2    Chen, S.3
  • 7
    • 84865195338 scopus 로고    scopus 로고
    • Assessment of candidemia-attributable mortality in critically ill patients using propensity score matching analysis
    • Gonzalez de Molina FJ, Leon C, Ruiz-Santana S, et al: Assessment of candidemia-attributable mortality in critically ill patients using propensity score matching analysis. Crit Care 2012; 16:R105
    • (2012) Crit Care , vol.16
    • Gonzalez De Molina, F.J.1    Leon, C.2    Ruiz-Santana, S.3
  • 8
    • 42549152508 scopus 로고    scopus 로고
    • Factors associated with candidemia caused by non-albicans Candida species versus Candida albicans in the intens ive care unit
    • Chow JK, Golan Y, Ruthazer R, et al: Factors associated with candidemia caused by non-albicans Candida species versus Candida albicans in the intens ive care unit. Clin Infect Dis 2008; 46:1206-1213
    • (2008) Clin Infect Dis , vol.46 , pp. 1206-1213
    • Chow, J.K.1    Golan, Y.2    Ruthazer, R.3
  • 9
    • 69049103182 scopus 로고    scopus 로고
    • Incidence of candidaemia and relationship with fluconazole use in an intensive care unit
    • Bassetti M, Ansaldi F, Nicolini L, et al: Incidence of candidaemia and relationship with fluconazole use in an intensive care unit. J Antimicrob Chemother 2009; 64:625-629
    • (2009) J Antimicrob Chemother , vol.64 , pp. 625-629
    • Bassetti, M.1    Ansaldi, F.2    Nicolini, L.3
  • 10
    • 67650508061 scopus 로고    scopus 로고
    • Amarcand study group: Epidemiology, management, and risk factors for death of invasive candida infections in critical care : Observational study in france 2005-2006
    • Leroy O, Gangneux JP, Montravers P, et al; AmarCand Study Group: Epidemiology, management, and risk factors for death of invasive Candida infections in critical care : A multicenter, prospective, observational study in France (2005-2006). Crit Care Med 2009; 37:1612-1618
    • (2009) Crit Care Med , vol.37 , pp. 1612-1618
    • Leroy, O.1    Gangneux, J.P.2    Montravers, P.3
  • 11
    • 38849127419 scopus 로고    scopus 로고
    • CandiRea study group: Candidemia an d candiduria in critically ill patients admitted to intensive care units in france: Incidence, molecular diversity, management and outcome
    • Bougnoux ME, Kac G, Aegerter P, et al; CandiRea Study Group: Candidemia an d candiduria in critically ill patients admitted to intensive care units in France: Incidence, molecular diversity, management and outcome. Intensive Care Med 2008; 34:292-299
    • (2008) Intensive Care Med , vol.34 , pp. 292-299
    • Bougnoux, M.E.1    Kac, G.2    Aegerter, P.3
  • 12
    • 83655163918 scopus 로고    scopus 로고
    • ECmm-fimua study group: Invasive fungal infections in the intensive care unit: A multicentre
    • prospective, observational study in Italy 2006-2008
    • Tortorano AM, Dho G, Prigitan o A, et al; ECMM-FIMUA Study Group: Invasive fungal infections in the intensive care unit: A multicentre, prospective, observational study in Italy (2006 -2008). Mycoses 2012; 55:73-79
    • (2012) Mycoses , vol.55 , pp. 73-79
    • Tortorano, A.M.1    Dho, G.2    Prigitano, A.3
  • 13
    • 33644506461 scopus 로고    scopus 로고
    • Epidemiological trends in nosocomial candidemia in intensive care
    • Bassetti M, Righi E, Costa A, et al: Epidemiological trends in nosocomial candidemia in intensive care. BMC Infect Dis 2006; 6:21
    • (2006) BMC Infect Dis , vol.6 , pp. 21
    • Bassetti, M.1    Righi, E.2    Costa, A.3
  • 14
    • 84879480870 scopus 로고    scopus 로고
    • China-SCAN Team: Invasive c andidiasis in intensive care units in China: A multicentre prospective observational study
    • Guo F, Yang Y, Kang Y, et al; China-SCAN Team: Invasive c andidiasis in intensive care units in China: A multicentre prospective observational study. J Antimicrob Chemother 2013; 68:1660-1668
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1660-1668
    • Guo, F.1    Yang, Y.2    Kang, Y.3
  • 15
    • 56049120807 scopus 로고    scopus 로고
    • Treatment-related risk factors for hospital mortality in Candida bloodstream infections
    • Labelle AJ, Micek ST, Roubinian N, et al: Treatment-related risk factors for hospital mortality in Candida bloodstream infections. Crit Care Med 2008; 36:2967-2972
    • (2008) Crit Care Med , vol.36 , pp. 2967-2972
    • Labelle, A.J.1    Micek, S.T.2    Roubinian, N.3
  • 16
    • 84871203700 scopus 로고    scopus 로고
    • Impact on hospital mort ality of catheter removal and adequate antifungal therapy in Candida spp bloodstream infections
    • Garnacho-Montero J, Dí az-Martín A, García-Cabrera E, et al: Impact on hospital mort ality of catheter removal and adequate antifungal therapy in Candida spp. bloodstream infections. J Antimicrob Chemother 2013; 68:206-213
    • (2013) J Antimicrob Chemother , vol.68 , pp. 206-213
    • Garnacho-Montero, J.1    Díaz-Martín, A.2    García-Cabrera, E.3
  • 17
    • 84863079846 scopus 로고    scopus 로고
    • Timing of suscepti bility-based antifungal drug administration in patients with Candida bloodstream infection: Correlation with outcomes
    • Grim SA, Berger K, Teng C, et al: Timing of suscepti bility-based antifungal drug administration in patients with Candida bloodstream infection: Correlation with outcomes. J Antimicrob Chemother 2012; 67:707-714
    • (2012) J Antimicrob Chemother , vol.67 , pp. 707-714
    • Grim, S.A.1    Berger, K.2    Teng, C.3
  • 18
    • 84859098509 scopus 로고    scopus 로고
    • Mycoses study group: Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: A patient-level quantitative review of randomized trials
    • Andes DR, Safdar N, Baddley JW, et al; Mycoses Study Group: Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: A patient-level quantitative review of randomized trials. Clin Infect Dis 2012; 54:1110-1122
    • (2012) Clin Infect Dis , vol.54 , pp. 1110-1122
    • Andes, D.R.1    Safdar, N.2    Baddley, J.W.3
  • 19
    • 0037109554 scopus 로고    scopus 로고
    • Effects of nosocomial candidemia on outcomes of critically ill patients
    • Blot SI, Vandewoude KH, Hoste EA, et al: Effects of nosocomial candidemia on outcomes of critically ill patients. Am J Med 2002; 113:480-485
    • (2002) Am J Med , vol.113 , pp. 480-485
    • Blot, S.I.1    Vandewoude, K.H.2    Hoste, E.A.3
  • 20
    • 84901497311 scopus 로고    scopus 로고
    • Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: A population-based surveillance in Spain
    • Aug
    • Puig-Asensio M, Padilla B, Garnacho-Montero M, et al: Epidemiology and predictive factors for early and late mortality in Candida bloodstream infections: A population-based surveillance in Spain. Clin Microbiol Inf ect 2013 Aug
    • (2013) Clin Microbiol Inf Ect
    • Puig-Asensio, M.1    Padilla, B.2    Garnacho-Montero, M.3
  • 21
    • 66949140382 scopus 로고    scopus 로고
    • Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection 2009 update by the infectious diseases society of america
    • Epub ahead of print
    • [Epub ahead of print] Mermel LA, Allon M, Bouza E, et al: Clinical practice guidelines for the diagnosis and management of intravascular catheter-related infection , 2009 Update by the Infectious Diseases Society of America , Clin Infect Dis, 2009,49, 1-45.
    • (2009) Clin Infect Dis , vol.49 , pp. 1-45
    • Mermel, L.A.1    Allon, M.2    Bouza, E.3
  • 22
    • 0022256529 scopus 로고
    • APACHE II: A severity of disease classification system
    • Knaus WA, Draper EA, Wagner DP, et al: APACHE II: A severity of disease classification system. Crit Care Med 1985; 13:818-829
    • (1985) Crit Care Med , vol.13 , pp. 818-829
    • Knaus, W.A.1    Draper, E.A.2    Wagner, D.P.3
  • 23
    • 0037396875 scopus 로고    scopus 로고
    • International sepsis definitions conference 2001 SCCM/ESICM/ACCP/ATS/SIS international sepsis definitions conference
    • Levy MM, Fink MP, Marshall JC, et al; International Sepsis Definitions Conference: 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intens ive Care Med 2003; 29:530-538
    • (2003) Intens Ive Care Med , vol.29 , pp. 530-538
    • Levy, M.M.1    Fink, M.P.2    Marshall, J.C.3
  • 24
    • 84901499897 scopus 로고    scopus 로고
    • The European Committee on Antimicrobial Susceptibility testing-EUCAST: Clinical breakpoints-Fungi. Table v 6.1. Available at Accessed May 1
    • The European Committee on Antimicrobial Susceptibility testing-EUCAST: Clinical breakpoints-Fungi. Table v 6.1. Available at: http://www.eucast.org/ clinical-breakpoints/. Accessed May 1, 2013
    • (2013)
  • 25
    • 34248573345 scopus 로고    scopus 로고
    • Genotyping of Candida orthopsilosis clinical isolates by amplification fragment length polymorphism reveals genetic diversity among independ ent isolates and strain maintenance within patients
    • Tavanti A, Hensgens LA, Ghelardi E, et al: Genotyping of Candida orthopsilosis clinical isolates by amplification fragment length polymorphism reveals genetic diversity among independ ent isolates and strain maintenance within patients. J Clin Microbiol 2007; 45:1455-1462
    • (2007) J Clin Microbiol , vol.45 , pp. 1455-1462
    • Tavanti, A.1    Hensgens, L.A.2    Ghelardi, E.3
  • 26
    • 11844300413 scopus 로고    scopus 로고
    • Candida orthopsilosis and Candida metapsilosis spp nov to rep lace Candida parapsilosis groups II and III
    • Tavanti A, Davidson AD, Gow NA, et al: Candida orthopsilosis and Candida metapsilosis spp. nov. to rep lace Candida parapsilosis groups II and III. J Clin Microbiol 2005; 43:284-292
    • (2005) J Clin Microbiol , vol.43 , pp. 284-292
    • Tavanti, A.1    Davidson, A.D.2    Gow, N.A.3
  • 27
    • 30744478706 scopus 로고    scopus 로고
    • PCR protocol for specific identification of Ca ndida nivariensis, a recently described pathogenic yeast
    • Alcoba-Fló rez J, del Pilar Arévalo M, González- Paredes FJ, et al: PCR protocol for specific identification of Ca ndida nivariensis, a recently described pathogenic yeast. J Clin Microbiol 2005; 43:6194-6196
    • (2005) J Clin Microbiol , vol.43 , pp. 6194-6196
    • Alcoba-Flórez, J.1    Del Pilar Arévalo, M.2    González- Paredes, F.J.3
  • 28
    • 40549124325 scopus 로고    scopus 로고
    • EUCAST definitive document EDef 7.1: Method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts
    • Rodriguez-Tudela JL, Arendrup MC, Barchiesi F, et al: EUCAST definitive document EDef 7.1: Method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts. Clin Microbiol Infect 2008; 14:398-405
    • (2008) Clin Microbiol Infect , vol.14 , pp. 398-405
    • Rodriguez-Tudela, J.L.1    Arendrup, M.C.2    Barchiesi, F.3
  • 29
    • 84862606187 scopus 로고    scopus 로고
    • EUCAST -AFST: EUCAST technical note on the EUCAST definitive document EDef 7.2: Method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 ( EUCAST-AFST)
    • Arendrup MC, Cuenca-Estrella M, Lass-Flörl C, et al; EUCAST -AFST: EUCAST technical note on the EUCAST definitive document EDef 7.2: Method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 ( EUCAST-AFST). Clin Microbiol Infect 2012; 18:E246-E247
    • (2012) Clin Microbiol Infect , vol.18
    • Arendrup, M.C.1    Cuenca-Estrella, M.2    Lass-Flörl, C.3
  • 30
    • 20144388435 scopus 로고    scopus 로고
    • Barcelona candidemia project study group: Epidemiology and predictors of mortality in cases of candida bloodstream infection: Results from population-based surve illance, barcelona, spain, from 2002 to 2003
    • Almirante B, Rodrí guez D, Park BJ, et al; Barcelona Candidemia Project Study Group: Epidemiology and predictors of mortality in cases of Candida bloodstream infection: Results from population-based surve illance, Barcelona, Spain, from 2002 to 2003. J Clin Microbiol 2005; 43:1829-1835
    • (2005) J Clin Microbiol , vol.43 , pp. 1829-1835
    • Almirante, B.1    Rodrí Guez, D.2    Park, B.J.3
  • 31
    • 84859613323 scopus 로고    scopus 로고
    • FUNGEMYCA Study Group: Epidemiology, species distribution and in vitro antifungal susceptibility of fungaemia in a Spanish multicentre prospective survey
    • Pemá n J, Cantón E, Quindós G, et al; FUNGEMYCA Study Group: Epidemiology, species distribution and in vitro antifungal susceptibility of fungaemia in a Spanish multicentre prospective survey. J Antimicrob Chemother 2012; 67:1181-1187
    • (2012) J Antimicrob Chemother , vol.67 , pp. 1181-1187
    • Pemán, J.1    Cantón, E.2    Quindós, G.3
  • 32
    • 33646552686 scopus 로고    scopus 로고
    • Epidemiology, risk factors, and prognosis of Candida parapsilosis bloodstream infections: Case-control population-based surveillance study of patients in Barcelona, Spain, from 2002 to 2003
    • Almirante B, Rodrí guez D, Cuenca-Estrella M, et al: Epidemiology, risk factors, and prognosis of Candida parapsilosis bloodstream infections: Case-control population-based surveillance study of patients in Barcelona, Spain, from 2002 to 2003. J Clin M icrobiol 2006; 44:1681-1685
    • (2006) J Clin M Icrobiol , vol.44 , pp. 1681-1685
    • Almirante, B.1    Rodríguez, D.2    Cuenca-Estrella, M.3
  • 33
    • 60549098868 scopus 로고    scopus 로고
    • Infectious diseases society of america: Clinical practice guidelines for the management of candidiasis 2009 update by the infectious diseases society of America
    • Pappas PG, Kauffman CA, Andes D, et al; Infectious Diseases Society of America: Clinical practice guidelines for the management of candidiasis: 2009 update by the Infectious Diseases Society of America. Clin Infect Dis 2009; 48:503-535
    • (2009) Clin Infect Dis , vol.48 , pp. 503-535
    • Pappas, P.G.1    Kauffman, C.A.2    Andes, D.3
  • 34
    • 78751679139 scopus 로고    scopus 로고
    • French Mycosis Study Group: Recent exposure to caspofungin or fluconazo le influences the epidemiology of candidemia: A prospective multicenter study involving 2,441 patients
    • Lortholary O, Desnos-Ollivier M, Sitbon K, et al; French Mycosis Study Group: Recent exposure to caspofungin or fluconazo le influences the epidemiology of candidemia: A prospective multicenter study involving 2,441 patients. Antimicrob Agents Chemother 2011; 55:532-538
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 532-538
    • Lortholary, O.1    Desnos-Ollivier, M.2    Sitbon, K.3
  • 35
    • 38749151566 scopus 로고    scopus 로고
    • Increasing incidence of Candida parapsilosis candidemia with caspofungin usage
    • Forrest GN, Weekes E, Johnson JK: Increasing incidence of Candida parapsilosis candidemia with caspofungin usage. J Infect 2008; 56:126-129
    • (2008) J Infect , vol.56 , pp. 126-129
    • Forrest, G.N.1    Weekes, E.2    Johnson, J.K.3
  • 36
    • 33846025137 scopus 로고    scopus 로고
    • Association of fluconazole area under the concentration-time curve/MIC and d ose/MIC ratios with mortality in nonneutropenic patients with candidemia
    • Pai MP, Turpin RS, Garey KW: Association of fluconazole area under the concentration-time curve/MIC and d ose/MIC ratios with mortality in nonneutropenic patients with candidemia. Antimicrob Agents Chemother 2007; 51:35-39
    • (2007) Antimicrob Agents Chemother , vol.51 , pp. 35-39
    • Pai, M.P.1    Turpin, R.S.2    Garey, K.W.3
  • 37
    • 84867709158 scopus 로고    scopus 로고
    • ESCMID fungal infection study group: ESCMID guideline for the diagnosis and management of Candida diseases 2012: Non-neutropenic adult patients
    • Cornely OA, Bassetti M, Calandra T, et al; ESCMID Fungal Infection Study Group: ESCMID*guideline for the diagnosis and management of Candida diseases 2012: Non-neutropenic adult patients. Cflin Microbiol Infect 2012; 18(Suppl 7):19-37
    • (2012) Clin Microbiol Infect , vol.18 , Issue.SUPPL. 7 , pp. 19-37
    • Cornely, O.A.1    Bassetti, M.2    Calandra, T.3
  • 38
    • 84856576829 scopus 로고    scopus 로고
    • French mycoses study group: Candida spp. with acquired echinocandin resistance, France 2004-2010
    • Dannaoui E, Desnos-Ollivier M, Garcia-Hermoso D, et al; French Mycoses Study Group: Candida spp. with acquired echinocandin resistance, France, 2004-2010. Emerg Infect Dis 2012; 18:86-90
    • (2012) Emerg Infect Dis , vol.18 , pp. 86-90
    • Dannaoui, E.1    Desnos-Ollivier, M.2    Garcia-Hermoso, D.3
  • 39
    • 84878342622 scopus 로고    scopus 로고
    • Increasing echinocandin resistance in Candida glabrata: Clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations
    • Alexander BD, Johnson MD, Pfeiffer CD, et al: Increasing echinocandin resistance in Candida glabrata: Clinical failure correlates with presence of FKS mutations and elevated minimum inhibitory concentrations. Clin Inf ect Dis 2013; 56:1724-1732
    • (2013) Clin Inf Ect Dis , vol.56 , pp. 1724-1732
    • Alexander, B.D.1    Johnson, M.D.2    Pfeiffer, C.D.3
  • 40
    • 84861497629 scopus 로고    scopus 로고
    • Septic shock attributed to Candida infection: Importance of empiric therapy and source control
    • Kollef M, Micek S, Hampton N, et al: Septic shock attributed to Candida infection: Importance of empiric therapy and source control. Clin Infect Dis 2012; 54:1739-1746
    • (2012) Clin Infect Dis , vol.54 , pp. 1739-1746
    • Kollef, M.1    Micek, S.2    Hampton, N.3
  • 41
    • 77954694558 scopus 로고    scopus 로고
    • Early removal of central venous catheter in patients with candidemia does not improve outcome: Analysis of 842 patients from 2 randomized clinical trial s
    • Nucci M, Anaissie E, Betts RF, et al: Early removal of central venous catheter in patients with candidemia does not improve outcome: Analysis of 842 patients from 2 randomized clinical trial s. Clin Infect Dis 2010; 51:295-303
    • (2010) Clin Infect Dis , vol.51 , pp. 295-303
    • Nucci, M.1    Anaissie, E.2    Betts, R.F.3
  • 42
    • 24144483474 scopus 로고    scopus 로고
    • Delaying the empiric treatment of Candida bloodstream infection until positive blood culture results are obtained: A potentia l risk factor for hospital mortality
    • Morrell M, Fraser VJ, Kollef MH: Delaying the empiric treatment of Candida bloodstream infection until positive blood culture results are obtained: A potentia l risk factor for hospital mortality. Antimicrob Agents Chemother 2005; 49:3640-3645
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3640-3645
    • Morrell, M.1    Fraser, V.J.2    Kollef, M.H.3
  • 43
    • 77954720403 scopus 로고    scopus 로고
    • A multicentre study to evaluate the impact of timing of caspofungin adm inistration on outcomes of invasive candidiasis in non-immunocompromised adult patients
    • Hsu DI, Nguyen M, Nguyen L, et al: A multicentre study to evaluate the impact of timing of caspofungin adm inistration on outcomes of invasive candidiasis in non-immunocompromised adult patients. J Antimicrob Chemother 2010; 65:1765-1770
    • (2010) J Antimicrob Chemother , vol.65 , pp. 1765-1770
    • Hsu, D.I.1    Nguyen, M.2    Nguyen, L.3
  • 44
    • 34548138992 scopus 로고    scopus 로고
    • Adequacy of empiri cal antifungal therapy and effect on outcome among patients with invasive Candida species infections
    • Parkins MD, Sabuda DM, Elsayed S, et al: Adequacy of empiri cal antifungal therapy and effect on outcome among patients with invasive Candida species infections. J Antimicrob Chemother 2007; 60:613-618
    • (2007) J Antimicrob Chemother , vol.60 , pp. 613-618
    • Parkins, M.D.1    Sabuda, D.M.2    Elsayed, S.3
  • 45
    • 33745313876 scopus 로고    scopus 로고
    • Time to initiati on of fluconazole therapy impacts mortality in patients with candidemia: A multi-institutional study
    • Garey KW, Rege M, Pai MP, et al: Time to initiati on of fluconazole therapy impacts mortality in patients with candidemia: A multi-institutional study. Clin Infect Dis 2006; 43:25-31
    • (2006) Clin Infect Dis , vol.43 , pp. 25-31
    • Garey, K.W.1    Rege, M.2    Pai, M.P.3
  • 46
    • 67650486324 scopus 로고    scopus 로고
    • Cava Study Group: Usefulness of the " Candida score" for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: A prospective multicenter stu dy
    • Leó n C, Ruiz-Santana S, Saavedra P, et al; Cava Study Group: Usefulness of the " Candida score" for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: A prospective multicenter stu dy. Crit Care Med 2009; 37:1624-1633
    • (2009) Crit Care Med , vol.37 , pp. 1624-1633
    • León, C.1    Ruiz-Santana, S.2    Saavedra, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.