Three new cembranoid-type diterpenes from Red Sea soft coral Sarcophyton glaucum: Isolation and antiproliferative activity against HepG2 cells

European Journal of Medicinal Chemistry

Volumn 81, Issue , 2014, Pages 314-322

  Al Lihaibi, Sultan S ^a   Alarif, Walied M ^a   Abdel Lateff, Ahmed ^a,b   Ayyad, Seif Eldin N ^a   Abdel Naim, Ashraf B ^a   El Senduny, Fardous F ^c   Badria, Farid A ^d  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b Minia University   (Egypt)

^c Mansoura University   (Egypt)

^d University of Mansoura   (Egypt)

Author keywords

Antiproliferative; Cembranes; HepG2; PC 3; Sarcophyton

Indexed keywords

10(14)AROMADENDRENE; ANTINEOPLASTIC AGENT; CASPASE 3; CEMBRANOID; DEOXOSARCOPHINE; DITERPENE; DOXORUBICIN; SARCOPHINE; SARCOPHYTOLIDE B; SARCOPHYTOLIDE C; SARCOPHYTOLOL; SESQUITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CELL ISOLATION; CHEMICAL STRUCTURE; CLINICAL EVALUATION; CORAL; CYTOTOXICITY; DRUG ISOLATION; HEPG2 CELL LINE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; IC 50; MALE; MASS SPECTROMETRY; MCF 7 CELL LINE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; PROSTATE CANCER CELL LINE; SARCOPHYTON GLAUCUM; SEA; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET RADIATION; ANIMAL; ANTHOZOA; CELL CYCLE; CELL PROLIFERATION; CHEMISTRY; CHLOROCEBUS AETHIOPS; DOSE RESPONSE; DRUG EFFECTS; DRUG SCREENING; ISOLATION AND PURIFICATION; STRUCTURE ACTIVITY RELATION; TUMOR CELL LINE; VERO CELL LINE;

ANIMALS; ANTHOZOA; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HEP G2 CELLS; HUMANS; MCF-7 CELLS; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP; VERO CELLS;

EID: 84901309221     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2014.05.016     Document Type: Article

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