Selective cytotoxic effects on human breast carcinoma of new methoxylated flavonoids from Euryops arabicus grown in Saudi Arabia

European Journal of Medicinal Chemistry

Volumn 66, Issue , 2013, Pages 204-210

  Alarif, Walied M ^a   Abdel Lateff, Ahmed ^a,c   Al Abd, Ahmed M ^a,d   Basaif, Salim A ^a   Badria, Farid A ^b   Shams, Maher ^e   Ayyad, Seif Eldin N ^a,b  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b MANSOURA UNIVERSITY   (Egypt)

^c Minia University   (Egypt)

^d NATIONAL RESEARCH CENTRE   (Egypt)

^e MANSOURA UNIVERSITY   (Egypt)

Author keywords

Anti proliferative; Diterpene; Flavones; HepG2; MCF 7; S phase

Indexed keywords

18,19 DIHYDROXY KAURA 16 EN 3 ONE; 3',8 DIHYDROXY 4',5',6,7 TETRAMETHOXYFLAVONE; 7 HYDROXY 3',4',6,8 TETRAMETHOXY FLAVONE; ASCORBIC ACID; ECHINACEA PURPUREA EXTRACT; EURYOPS ARABICUS EXTRACT; FLAVONOID; FLUOROURACIL; FREE RADICAL; PLANT EXTRACT; UNCLASSIFIED DRUG; 3',8 DIHYDROXY 4',6,7 TETRAMETHOXYFLAVONE; 7 HYDROXY 3',4',6,8 TETRAMETHOXYFLAVONE; CYTOTOXIC AGENT; METHOXYLATED FLAVONOID;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL STRAIN MCF 7; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; EURYOPS ARABICUS; HETERONUCLEAR MULTIPLE BOND CORRELATION; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; IMMUNOSUPPRESSIVE TREATMENT; LIPID PEROXIDATION; LYMPHOCYTE TRANSFORMATION; MASS SPECTROMETRY; MEDICINAL PLANT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PERIPHERAL LYMPHOCYTE; S PHASE CELL CYCLE CHECKPOINT; SAUDI ARABIA; STRUCTURE ACTIVITY RELATION; THIN LAYER CHROMATOGRAPHY; VERO CELL; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG SELECTIVITY; HEPG2 CELL LINE; HERBAL MEDICINE; HETERONUCLEAR SINGLE QUANTUM COHERENCE; IC50; MCF 7 CELL LINE; PROTON NUCLEAR MAGNETIC RESONANCE; VERO CELL LINE;

EID: 84879486659     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.05.025     Document Type: Article

References (28)

1. F. Li, S. Awale, Y. Tezuka, S. Kadota, Biol. Pharm. Bull. 32 (2009) 2075-2078.
2. P. Balachandran, R. Govindarajan, Pharmacol. Res. 51 (2005) 19-30.
3. P. Boyle, B. Levin, World Cancer Report (Section 1.1), World Health Organization, International Agency for Research on Cancer, Lyon, 2008, pp. 12-39.
4. J.C. Chang, Biomed. Pharmacother. 52 (1998) 133-136.
5. F. Badria, M. Ameen, M.R. Akl, Z. Naturforsch. 62c (2007) 656-660.
6. F. Badria, A. Dawidar, W. Houssen, T.S. Wayne, Z. Naturforsch. 60c (2005) 139-142.
7. F. Badria, M. ElGayyar, Bull. Chim. Farmac. 140 (2001) 267-270.
8. A.A. Anderberg, B.G. Baldwin, R.G. Bayer, Compositae, in: K. Kubitzki (Ed.), The Families and Genera of Vascular Plants, in: J.W. Kadereit, C. Jeffrey (Eds.), Flowering Plants, Dicots, Asterales, VIII, Springer, Berlin, Heidelberg, New York, 2007, p. 61.
9. D.L.H. Hannes, Q.C.C. Rieseberg, Crop Evol. 55 (2008) 1141-1147.
10. Ö.E. Berrin, O. Ilkay, T. Gülnur, Z. Naturforsch. 61c (2006) 632-638.
11. S.-E.N. Ayyad, A. Abdel-Lateff, W.M. Alarif, F.R. Patacchiol, i.F.A. Badria, S.T. Ezmirly, Env. Toxicol. Pharmacol. 33 (2012) 245-251.
12. S.-E.N. Ayyad, A. Abdel-Lateff, S.A. Basaif, W.T. Shier, Pharmacog. Res. 3 (2011) 189-193.
13. M. Proksch, P. Proksch, G. Weissenboeck, E. Rodriguez, Phytochemistry 21 (1982) 1833-1835.
14. T.K.P. Nguyen, K.P.P. Nguyen, F.S. Kamounah, W. Zhanga, P.E. Hansena, Nucl. Magn. Reson. 47 (2009) 1043-1053.
15. P.C. Rwangabo, M.C.P. Corthoutd, A.V. Erghe, A.J. Vlietinck, J. Nat. Prod. 5 (1988) 966-968.
16. M. Ozturk, U. Kolak, G. Topcu, S. Oksuz, M.I. Choudhary, Food Chem. 126 (1988) 31-38.
17. M. Miski, A. Ulubelan, T.J. Mabry, Phytochemistry 22 (1983) 2093-2094.
18. E. Maldonado, A. Ortega, Phytochemistry 45 (1997) 1461-1464.
19. G. Topcua, A.l. Ertas, M. Öztürk, D. Dincel, T. Kilic, B. Halfon, Phytochem. Lett. 4 (2011) 436-439.
20. P.T. Thuong, T.H.M. Pham, T.V.T. Le, T.T. Dao, T.T. Dang, Q.T. Nguyen, W.K. Oh, Bioorg. Med. Chem. Lett. 22 (2012) 1122-1124.
21. Y. Meng, A.J. Krzysiak, M.J. Durako, J.I. Kunzelman, J.L.C. Wright, Phytochemistry 69 (2008) 2603-2608.
22. T.J. Mabry, K.R. Markham, M.B. Thomas, The Systematic Identification of Flavonoids, Springer-Verlag, Berlin, Heidelberg, New York, 1970.
23. F.A. Badria, M. Abu-Karam, R.M. Botros, G.T. Maatooq, M.M. Amer, Biosci. Biotech. Res. Asia 1 (2003) 1-7.
24. F.A. Badria, R.M. Botros, G.T. Maatooq, M.M. Amer, Z. Naturforsch. 58c (2003) 505-516.
25. R.M. Botros, F.A. Badria, G.T. Maatooq, M.M. Amer, Z. Naturforsch. 59c (2004) 468-476.
26. M.A. El-Ansari, D. Barron, M.F. Abdalla, N.A.M. Saleh, J.L. Le Quere, Phytochemistry 30 (1991) 1169-1173.
27. F.P. Vanderlúcia, C.A. Luiz, W.E. Barbosa, W.H. Oliver, P.C. Mariluze, J. Braz. Chem. Soc. 13 (2002) 276-280.
28. P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. McMahon, D. Vistica, J.T. Warren, H. Bokesch, S. Kenney, M.R. Boyd, J. Natl. Cancer Inst. 82 (1990) 1107-1112.