Screening for selective inhibitors of xanthine oxidase from Flos Chrysanthemum using ultrafiltration LC-MS combined with enzyme channel blocking

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 961, Issue , 2014, Pages 56-61

  Song, Hui Peng ^a   Zhang, Hui ^a   Fu, Yu ^a   Mo, Hua yan ^a   Zhang, Mu ^a   Chen, Jun ^a   Li, Ping ^a  

^a China Pharmaceutical University   (China)

Author keywords

Febuxostat; Flos chrysanthemum; Liquid chromatography mass spectrometry; Ultrafiltration; Xanthine oxidase

Indexed keywords

CARBOHYDRATES; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; EXPERIMENTS; FLAVONOIDS; MEDICINE; ULTRAFILTRATION;

BIOACTIVE COMPONENTS; CHROMATOGRAPHIC PROFILES; FEBUXOSTAT; FLOS CHRYSANTHEMUM; LIQUID CHROMATOGRAPHY/MASS SPECTROMETRY; STRUCTURE-FUNCTION RELATIONSHIP; TRADITIONAL CHINESE MEDICINE; XANTHINE OXIDASE;

ENZYMES;

ANTIGOUT AGENT; APIGENIN; APIGETRIN; ENZYME INHIBITOR; FEBUXOSTAT; FLAVONE DERIVATIVE; GLUCOSIDE; HERBACEOUS AGENT; LUTEOLIN; LUTEOLIN-7-O-GLUCOSIDE; THIAZOLE DERIVATIVE; XANTHINE OXIDASE;

ANTAGONISTS AND INHIBITORS; CHEMISTRY; CHRYSANTHEMUM; DRUG EFFECTS; ENZYME ACTIVE SITE; FLOWER; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PROCEDURES; ULTRAFILTRATION;

APIGENIN; CATALYTIC DOMAIN; CHROMATOGRAPHY, LIQUID; CHRYSANTHEMUM; DRUGS, CHINESE HERBAL; ENZYME INHIBITORS; FLAVONES; FLOWERS; GLUCOSIDES; GOUT SUPPRESSANTS; LUTEOLIN; MASS SPECTROMETRY; THIAZOLES; ULTRAFILTRATION; XANTHINE OXIDASE;

EID: 84901300045     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2014.05.001     Document Type: Article

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