Screening for ligands of human retinoid X receptor-α using ultrafiltration mass spectrometry

Analytical Chemistry

Volumn 79, Issue 24, 2007, Pages 9398-9402

  Liu, Dongting ^a   Guo, Jian ^a   Luo, Yan ^a   Broderick, David J ^b   Schimerlik, Michael I ^b   Pezzuto, John M ^c   Van Breemen, Richard B ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b OREGON STATE UNIVERSITY   (United States)

^c UNIVERSITY OF HAWAII AT HILO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CELL PROLIFERATION; DIMERS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; TRANSCRIPTION FACTORS; ULTRAFILTRATION;

CELL DIFFERENTIATION; NATURAL PRODUCT EXTRACTS; NUCLEAR RECEPTOR HETERODIMERS;

LIGANDS;

6 [1 (5,6,7,8 TETRAHYDRO 3,5,5,8,8 PENTAMETHYL 2 NAPHTHYL)CYCLOPROPYL]NICOTINIC ACID; ALITRETINOIN; DIMETHYL SULFOXIDE; DOCOSAHEXAENOIC ACID; LIGAND; RETINOID X RECEPTOR ALPHA;

ANALYTIC METHOD; ARTICLE; ASSAY; BINDING AFFINITY; HUMAN; LIGAND BINDING; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SCREENING; TANDEM MASS SPECTROMETRY; ULTRAFILTRATION;

CHEMOPREVENTION; CHROMATOGRAPHY, LIQUID; DRUG EVALUATION, PRECLINICAL; HUMANS; LIGANDS; MASS SPECTROMETRY; RETINOID X RECEPTORS; ULTRAFILTRATION;

EID: 37249026697     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac701701k     Document Type: Article

References (22)

1. Germain, P.; Chambon, P.; Eichele, G.; Evans, R. M.; Lazar, M. A.; Leid, M.; De Lera, A. R.; Lotan, R.; Mangelsdorf, D. J.; Gronemeyer, H. Pharmacol. Rev. 2006, 58, 760-772.
2. Yu, V. C.; Delsert, C.; Andersen, B.; Holloway, J. M.; Devary, O. V.; Naar, A. M.; Kim, S. Y.; Boutin, J. M.; Glass, C. K.; Rosenfeld, M. G. Cell 1991, 67, 1251-1266.
3. Leid, M.; Kastner, P.; Lyons, R.; Nakshatri, H.; Saunders, M.; Zacharewski, T.; Chen, J. Y.; Staub, A.; Garnier, J. M.; Mader, S. Cell 1992, 68, 377-395.
4. Zhang, X. K.; Hoffmann, B.; Tran, P. B.; Graupner, G.; Pfahl, M. Nature 1992, 355, 441-446.
5. Sporn, M. B.; Suh, N. Nat. Rev. Cancer 2002, 2, 537-543.
6. Dragnev, K. H.; Petty, W. J.; Shah, S.; Biddle, A.; Desai, N. B.; Memoli, V.; Rigas, J. R.; Dmitrovsky, E. J. Clin. Oncol. 2005, 23, 8757-8764.
7. Shulman, A. I.; Mangelsdorf, D. J. N. Engl. J Med. 2005, 353, 604-615.
8. Lowe, M. N.; Plosker, G. L. Am. J Clin. Dermatol. 2000, 1, 245-250; discussion 251-252.
9. Lengqvist, J.; Mata De Urquiza, A.; Bergman, A. C.; Willson, T. M.; Sjovall, J.; Perlmann, T.; Griffiths, W. J. Mol. Cell. Proteomics 2004, 3, 692-703.
10. Lengqvist, J.; Alvelius, G.; Jornvall, H.; Sjovall, J.; Perlmann, T.; Griffiths, W. J. J. Am. Soc. Mass Spectrom. 2005, 16, 1631-1640.
11. Lengqvist, J.; Mata de Urquiza, A.; Perlmann, T.; Sjovall, J.; Griffiths, W. J. J. Mass Spectrom. 2005, 40, 1448-1461.
12. van Breemen, R. B.; Huang, C. R.; Nikolic, D.; Woodbury, C. P.; Zhao, Y. Z.; Venton, D. L. Anal. Chem. 1997, 69, 2159-2164.
13. Zhao, Y. Z.; van Breemen, R. B.; Nikolic, D.; Huang, C. R.; Woodbury, C. P.; Schilling, A.; Venton, D. L. J. Med. Chem. 1997, 40, 4006-4012.
14. Nikolic, D.; van Breemen, R. B. Comb. Chem. High Throughput Screening 1998, 1, 47-55.
15. Nikolic, D.; Habibi-Goudarzi, S.; Corley, D. G.; Gafner, S.; Pezzuto, J. M.; van Breemen, R. B. Anal. Chem. 2000, 72, 3853-3859.
16. Gu, C.; Nikolic, D.; Lai, J.; Xu, X.; van Breemen, R. B. Comb. Chem. High Throughput Screening 1999, 2, 353-359.
17. Sun, Y.; Gu, C.; Liu, X.; Liang, W.; Yao, P.; Bolton, J. L.; van Breemen, R. B. J. Am. Soc. Mass Spectrom. 2005, 16, 271-279.
18. Yan, X.; Broderick, D.; Leid, M. E.; Schimerlik, M. I.; Deinzer, M. L. Biochemistry 2004, 43, 909-917.
19. Soria-Mercado, I. E.; Prieto-Davo, A.; Jensen, P. R.; Fenical, W. J. Nat. Prod. 2005, 68, 904-910.
20. Boehm, M. F.; Zhang, L.; Zhi, L.; McClurg, M. R.; Berger, E.; Wagoner, M.; Mais, D. E.; Suto, C. M.; Davies, J. A.; Heyman, R. A. J. Med. Chem. 1995, 38, 3146-3155.
21. Heyman, R. A.; Mangelsdorf, D. J.; Dyck, J. A.; Stein, R. B.; Eichele, G.; Evans, R. M.; Thaller, C. Cell 1992, 68, 397-406.
22. de Urquiza, A M.; Liu, S.; Sjoberg, M.; Zetterstrom, R. H.; Griffiths, W.; Sjovall, J.; Perlmann, T. Science 2000, 290, 2140-2144.