In situ intestinal permeability and in vivo oral bioavailability of celecoxib in supersaturating self-emulsifying drug delivery system

Archives of Pharmacal Research

Volumn 37, Issue 5, 2014, Pages 626-635

  Song, Woo Heon ^a   Yeom, Dong Woo ^a   Lee, Dong Hoon ^a   Lee, Kyung Min ^a   Yoo, Hyun Joon ^a   Chae, Bo Ram ^a   Song, Seh Hyon ^a   Choi, Young Wook ^a  

^a Chung Ang University   (South Korea)

Author keywords

Bioavailability; Celecoxib; Intestinal permeability; SEDDS; Soluplus; Supersaturation

Indexed keywords

CELECOXIB; COSURFACTANT; POLYMER; POLYSORBATE 20; POLYVINYL CAPROLACTAM POLYVINYL ACETATE POLYETHYLENE GLYCOL GRAFT COPOLYMER; PROPYLENE GLYCOL MONOCAPRYLATE; SURFACTANT; TETRAGLYCOL; UNCLASSIFIED DRUG; CAPRYOL PROPYLENE GLYCOL MONOCAPRYLATE; CYCLOOXYGENASE 2 INHIBITOR; DRUG CARRIER; EMULSION; GLYCOFUROL; MACROGOL DERIVATIVE; MICELLE; POLYSORBATE; POLYVINYL CAPROLACTAM-POLYVINYL ACETATE-POLYETHYLENE GLYCOL GRAFT COPOLYMER; POLYVINYL DERIVATIVE; PROPANEDIOL DERIVATIVE; PYRAZOLE DERIVATIVE; SULFONAMIDE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTESTINE ABSORPTION; INTESTINE MUCOSA PERMEABILITY; INTESTINE PERFUSION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; SELF EMULSIFYING DRUG DELIVERY SYSTEM; TIME TO MAXIMUM PLASMA CONCENTRATION; ANIMAL; BIOAVAILABILITY; BLOOD; CHEMISTRY; EMULSION; INTESTINE; MEDICINAL CHEMISTRY; METABOLISM; MICELLE; ORAL DRUG ADMINISTRATION; PERMEABILITY; PHARMACEUTICS; PROCEDURES; SPRAGUE DAWLEY RAT; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, LIQUID; CYCLOOXYGENASE 2 INHIBITORS; DRUG CARRIERS; EMULSIONS; INTESTINAL ABSORPTION; INTESTINES; MALE; MICELLES; PERMEABILITY; POLYETHYLENE GLYCOLS; POLYMERS; POLYSORBATES; POLYVINYLS; PROPYLENE GLYCOLS; PYRAZOLES; RATS, SPRAGUE-DAWLEY; SULFONAMIDES; SURFACE-ACTIVE AGENTS; TANDEM MASS SPECTROMETRY; TECHNOLOGY, PHARMACEUTICAL;

EID: 84901279675     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-013-0202-7     Document Type: Article

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