Retrograde coronary vein infusion of cardiac explant-derived c-Kit + cells improves function in ischemic heart failure

Journal of Heart and Lung Transplantation

Volumn 33, Issue 6, 2014, Pages 644-653

  Zakharova, Liudmila ^a   Nural Guvener, Hikmet ^a   Feehery, Lorraine ^a   Popovic, Snjezana ^a   Nimlos, James ^a   Gaballa, Mohamed A ^a  

^a SUN HEALTH RESEARCH INSTITUTE   (United States)

Author keywords

cardiac stem cells; congestive heart failure; myocardial infarction; retrograde venous perfusion; stem cell transplantation

Indexed keywords

COLLAGEN; GREEN FLUORESCENT PROTEIN; STEM CELL FACTOR; STEM CELL FACTOR RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CAPILLARY DENSITY; CELL DIFFERENTIATION; CONGESTIVE HEART FAILURE; CONTROLLED STUDY; CORONARY VEIN; ENDOTHELIUM CELL; HEART FUNCTION; HEART HEMODYNAMICS; HEART INFARCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE CELL; IN VITRO STUDY; INFUSION; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RETROGRADE CORONARY VEIN INFUSION; SMOOTH MUSCLE FIBER; STEM CELL TRANSPLANTATION; ANIMAL; COMPLICATION; CORONARY BLOOD VESSEL; HEART FAILURE; HEART VENTRICLE REMODELING; INTRAVENOUS DRUG ADMINISTRATION; MYOCARDIAL INFARCTION; PATHOLOGY; PROCEDURES; SPRAGUE DAWLEY RAT; TRANSPLANTATION;

ANIMALS; CORONARY VESSELS; HEART FAILURE; INFUSIONS, INTRAVENOUS; MALE; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-KIT; RATS, SPRAGUE-DAWLEY; STEM CELL TRANSPLANTATION; VENTRICULAR REMODELING;

EID: 84901263657     PISSN: 10532498     EISSN: 15573117     Source Type: Journal    
DOI: 10.1016/j.healun.2014.03.006     Document Type: Article

References (41)

1. P. Donndorf, B.E. Strauer, and A. Haverich et al. Stem cell therapy for the treatment of acute myocardial infarction and chronic ischemic heart disease Curr Pharm Biotechnol 14 2013 12 19
2. I.H. Schulman, and J.M. Hare Key developments in stem cell therapy in cardiology Regen Med 7 2012 17 24
3. A.P. Beltrami, L. Barlucchi, and D. Torella et al. Adult cardiac stem cells are multipotent and support myocardial regeneration Cell 114 2003 763 776
4. K.L. Laugwitz, A. Moretti, and J. Lam et al. Postnatal isl1+ cardioblasts enter fully differentiated cardiomyocyte lineages Nature 433 2005 647 653
5. H. Oh, S.B. Bradfute, and T.D. Gallardo et al. Cardiac progenitor cells from adult myocardium: homing, differentiation, and fusion after infarction Proc Natl Acad Sci USA 100 2003 12313 12318
6. B. Dawn, A.B. Stein, and K. Urbanek et al. Cardiac stem cells delivered intravascularly traverse the vessel barrier, regenerate infarcted myocardium, and improve cardiac function Proc Natl Acad Sci USA 102 2005 3766 3771
7. M. Rota, M.E. Padin-Iruegas, and Y. Misao et al. Local activation or implantation of cardiac progenitor cells rescues scarred infarcted myocardium improving cardiac function Circ Res 103 2008 107 116
8. A.R. Chugh, G.M. Beache, and J.H. Loughran et al. Administration of cardiac stem cells in patients with ischemic cardiomyopathy: the SCIPIO trial: surgical aspects and interim analysis of myocardial function and viability by magnetic resonance Circulation 126 suppl 2012 S54 S64
9. P. Boekstegers, and C. Kupatt Current concepts and applications of coronary venous retroinfusion Basic Res Cardiol 99 2004 373 381
10. C. Kupatt, R. Hinkel, and M. Lamparter et al. Retroinfusion of embryonic endothelial progenitor cells attenuates ischemia-reperfusion injury in pigs: role of phosphatidylinositol 3-kinase/AKT kinase Circulation 2005 112:I-117-22
11. N. Hatori, P.O. Sjoquist, and C. Regardh et al. Pharmacokinetic analysis of coronary sinus retroinfusion in pigs. Ischemic myocardial concentrations in the left circumflex coronary arterial area using metoprolol as a tracer Cardiovasc Drugs Ther 5 1991 1005 1010
12. L. Ryden, H. Tadokoro, and P.O. Sjoquist et al. Pharmacokinetic analysis of coronary venous retroinfusion: a comparison with anterograde coronary artery drug administration using metoprolol as a tracer J Am Coll Cardiol 18 1991 603 612
13. K. Suzuki, B. Murtuza, and S. Fukushima et al. Targeted cell delivery into infarcted rat hearts by retrograde intracoronary infusion: distribution, dynamics, and influence on cardiac function Circulation 2004 110:II-225-30
14. M.A. Gaballa, J.N. Sunkomat, and H. Thai et al. Grafting an acellular 3-dimensional collagen scaffold onto a non-transmural infarcted myocardium induces neo-angiogenesis and reduces cardiac remodeling J Heart Lung Transplant 25 2006 946 954
15. D.R. Davis, E. Kizana, and J. Terrovitis et al. Isolation and expansion of functionally-competent cardiac progenitor cells directly from heart biopsies J Mol Cell Cardiol 49 2010 312 321
16. R.R. Smith, L. Barile, and H.C. Cho et al. Regenerative potential of cardiosphere-derived cells expanded from percutaneous endomyocardial biopsy specimens Circulation 115 2007 896 908
17. L. Zakharova, H. Nural-Guvener, and M.A. Gaballa Cardiac explant-derived cells are regulated by Notch-modulated mesenchymal transition PLoS One 7 2012 e37800
18. L. Zakharova, H. Nural-Guvener, and J. Nimlos et al. Chronic heart failure is associated with transforming growth factor beta-dependent yield and functional decline in atrial explant-derived c-Kit+ cells JAMA 2 2013 e000317
19. P. Pacher, T. Nagayama, and P. Mukhopadhyay et al. Measurement of cardiac function using pressure-volume conductance catheter technique in mice and rats Nat Protoc 3 2008 1422 1434
20. L. Zakharova, D. Mastroeni, and N. Mutlu et al. Transplantation of cardiac progenitor cell sheet onto infarcted heart promotes cardiogenesis and improves function Cardiovasc Res 87 2010 40 49
21. A. Itzhaki-Alfia, J. Leor, and E. Raanani et al. Patient characteristics and cell source determine the number of isolated human cardiac progenitor cells Circulation 120 2009 2559 2566
22. R. Mishra, K. Vijayan, and E.J. Colletti et al. Characterization and functionality of cardiac progenitor cells in congenital heart patients Circulation 123 2011 364 373
23. H.C. Ott, T.S. Matthiesen, and J. Brechtken et al. The adult human heart as a source for stem cells: repair strategies with embryonic-like progenitor cells Nat Clin Pract Cardiovasc Med 4 suppl 1 2007 S27 S39
24. M.A. Gaballa, and S. Goldman Gene transfer of endothelial nitric oxide isoform decreases rat hindlimb vascular resistance in vivo Hum Gene Ther 11 2000 1637 1646
25. J. Francis, R.M. Weiss, and S.G. Wei et al. Progression of heart failure after myocardial infarction in the rat Am J Physiol Regul Integr Comp Physiol 281 2001 R1734 R1745
26. S. Fukushima, S.R. Coppen, and J. Lee et al. Choice of cell-delivery route for skeletal myoblast transplantation for treating post-infarction chronic heart failure in rat PLoS One 3 2008 e3071
27. J. Bartunek, W. Wijns, and G.R. Heyndrickx et al. Timing of intracoronary bone-marrow-derived stem cell transplantation after ST-elevation myocardial infarction Nat Clin Pract Cardiovasc Med 3 suppl 1 2006 S52 S56
28. R. Bolli, X.L. Tang, and S.K. Sanganalmath et al. Intracoronary delivery of autologous cardiac stem cells improves cardiac function in a porcine model of chronic ischemic cardiomyopathy Circulation 128 2013 122 131
29. R. Llano, S. Epstein, and R. Zhou et al. Intracoronary delivery of mesenchymal stem cells at high flow rates after myocardial infarction improves distal coronary blood flow and decreases mortality in pigs Cathet Cardiovasc Interv 73 2009 251 257
30. Q. Li, Y. Guo, and Q. Ou et al. Intracoronary administration of cardiac stem cells in mice: a new, improved technique for cell therapy in murine models Basic Res Cardiol 106 2011 849 864
31. X.L. Tang, G. Rokosh, and S.K. Sanganalmath et al. Intracoronary administration of cardiac progenitor cells alleviates left ventricular dysfunction in rats with a 30-day-old infarction Circulation 121 2010 293 305
32. E.C. Perin, G.V. Silva, and J.A. Assad et al. Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction J Mol Cell Cardiol 44 2008 486 495
33. M. Vanderheyden, S. Vercauteren, and S. Mansour et al. Time-dependent effects on coronary remodeling and epicardial conductance after intracoronary injection of enriched hematopoietic bone marrow stem cells in patients with previous myocardial infarction Cell Transplant 16 2007 919 925
34. M. Yousef, C.M. Schannwell, and M. Kostering et al. The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial infarction J Am Coll Cardiol 53 2009 2262 2269
35. D.V. Baklanov, K.M. Moodie, and F.E. McCarthy et al. Comparison of transendocardial and retrograde coronary venous intramyocardial catheter delivery systems in healthy and infarcted pigs Catheter Cardiovasc Interv 68 2006 416 423
36. A. Ido, N. Hasebe, and H. Matsuhashi et al. Coronary sinus occlusion enhances coronary collateral flow and reduces subendocardial ischemia Am J Physiol Heart Circ Physiol 280 2001 H1361 H1367
37. K. Wu, X. Mo, and S. Lu et al. Retrograde delivery of stem cells: promising delivery strategy for myocardial regenerative therapy Clin Transplant 25 2011 830 833
38. P. Raake, G. von Degenfeld, and R. Hinkel et al. Myocardial gene transfer by selective pressure-regulated retroinfusion of coronary veins: comparison with surgical and percutaneous intramyocardial gene delivery J Am Coll Cardiol 44 2004 1124 1129
39. D.J. MacDonald, J. Luo, and T. Saito et al. Persistence of marrow stromal cells implanted into acutely infarcted myocardium: observations in a xenotransplant model J Thorac Cardiovasc Surg 130 2005 1114 1121
40. H.M. Thai, E. Juneman, and J. Lancaster et al. Implantation of a three-dimensional fibroblast matrix improves left ventricular function and blood flow after acute myocardial infarction Cell Transplant 18 2009 283 295
41. M. Di Nicola, C. Carlo-Stella, and M. Magni et al. Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli Blood 99 2002 3838 3843