A ten-microRNA signature identified from a genome-wide microRNA expression profiling in human epithelial ovarian cancer

PLoS ONE

Volumn 9, Issue 5, 2014, Pages

  Wang, Lin ^a   Zhu, Miao Jun ^b   Ren, Ai Min ^a   Wu, Hong Fei ^b   Han, Wu Mei ^b   Tan, Ruo Ying ^b   Tu, Rui Qin ^a  

^a FUDAN UNIVERSITY   (China)

^b Biovue Technology (China) Ltd   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HSA MIR 1271 5P; HSA MIR 130B 5P; HSA MIR 135B 3P; HSA MIR 141 5P; HSA MIR 15B 5P; HSA MIR 182 3P; HSA MIR 182 5P; HSA MIR 183 5P; HSA MIR 574 3P; HSA MIR 96 5P; MICRORNA; MICRORNA 141 5P; MICRORNA 182; MICRORNA 183; MICRORNA 200A; MICRORNA 200B; MICRORNA 200C; MICRORNA 429; MICRORNA 96 5P; UNCLASSIFIED DRUG; MIRN141 MICRORNA, HUMAN; MIRN182 MICRORNA, HUMAN; MIRN183 MICRORNA, HUMAN; MIRN200 MICRORNA, HUMAN; MIRN429 MICRORNA, HUMAN; MIRN96 MICRORNA, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; OVARY CARCINOMA; PREDICTION; REAL TIME POLYMERASE CHAIN REACTION; RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SUPPORT VECTOR MACHINE; UPREGULATION; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION; GENETICS; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PROCEDURES; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MICRORNAS; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; REPRODUCIBILITY OF RESULTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 84901242702     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0096472     Document Type: Article

References (27)

1. Jemal A, Bray F, Center MM, Ferlay J, Ward E, et al. (2011) Global cancer statistics. CA Cancer J Clin 61: 69-90.
2. Szabo CI, King MC (1995) Inherited breast and ovarian cancer. Hum Mol Genet 4 Spec No: 1811-1817.
3. Chan JK, Cheung MK, Husain A, Teng NN, West D, et al. (2006) Patterns and progress in ovarian cancer over 14 years. Obstet Gynecol 108: 521-528. (Pubitemid 44337091)
4. Jemal A, Siegel R, Ward E, Murray T, Xu J, et al. (2007) Cancer statistics, 2007. CA Cancer J Clin 57: 43-66. (Pubitemid 46148091)
5. Siegel R, Naishadham D, Jemal A (2012) Cancer statistics, 2012. CA Cancer J Clin 62: 10-29.
6. Ahmed FY, Wiltshaw E, A'Hern RP, Nicol B, Shepherd J, et al. (1996) Natural history and prognosis of untreated stage I epithelial ovarian carcinoma. J Clin Oncol 14: 2968-2975. (Pubitemid 26371455)
7. Etzioni R, Urban N, Ramsey S, McIntosh M, Schwartz S, et al. (2003) The case for early detection. Nat Rev Cancer 3: 243-252. (Pubitemid 37328860)
8. Wright JD, Shah M, Mathew L, Burke WM, Culhane J, et al. (2009) Fertility preservation in young women with epithelial ovarian cancer. Cancer 115: 4118-4126.
9. Menon U, Kalsi J, Jacobs I (2012) The UKCTOCS experience - reasons for hope? Int J Gynecol Cancer 22 Suppl 1: S18-20.
10. Gloss BS, Samimi G (2012) Epigenetic biomarkers in epithelial ovarian cancer. Cancer Lett.
11. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116: 281-297.
12. Huang Y, Shen XJ, Zou Q, Zhao QL (2010) Biological functions of microRNAs. Bioorg Khim 36: 747-752.
13. Mezzanzanica D, Bagnoli M, De Cecco L, Valeri B, Canevari S (2010) Role of microRNAs in ovarian cancer pathogenesis and potential clinical implications. Int J Biochem Cell Biol 42: 1262-1272.
14. Kuhlmann JD, Rasch J, Wimberger P, Kasimir-Bauer S (2012) microRNA and the pathogenesis of ovarian cancer - a new horizon for molecular diagnostics and treatment? Clin Chem Lab Med 50: 601-615.
15. Sing T, Sander O, Beerenwinkel N, Lengauer T (2005) ROCR: visualizing classifier performance in R. Bioinformatics 21: 3940-3941. (Pubitemid 41535515)
16. Wang X (2009) A PCR-based platform for microRNA expression profiling studies. RNA 15: 716-723.
17. Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, et al. (2007) A mammalian microRNA expression atlas based on small RNA library sequencing. Cell 129: 1401-1414. (Pubitemid 46970709)
18. Hu X, Macdonald DM, Huettner PC, Feng Z, El Naqa IM, et al. (2009) A miR-200 microRNA cluster as prognostic marker in advanced ovarian cancer. Gynecol Oncol 114: 457-464.
19. Liu Z, Liu J, Segura MF, Shao C, Lee P, et al. (2012) MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma. J Pathol 228: 204-215.
20. Segura MF, Hanniford D, Menendez S, Reavie L, Zou X, et al. (2009) Aberrant miR-182 expression promotes melanoma metastasis by repressing FOXO3 and microphthalmia-associated transcription factor. Proc Natl Acad Sci U S A 106: 1814-1819.
21. Peart TM, Correa RJ, Valdes YR, Dimattia GE, Shepherd TG (2012) BMP signalling controls the malignant potential of ascites-derived human epithelial ovarian cancer spheroids via AKT kinase activation. Clin Exp Metastasis 29: 293-313.
22. Xu X, Dong Z, Li Y, Yang Y, Yuan Z, et al. (2013) The upregulation of signal transducer and activator of transcription 5-dependent microRNA-182 and microRNA-96 promotes ovarian cancer cell proliferation by targeting forkhead box O3 upon leptin stimulation. Int J Biochem Cell Biol 45: 536-545.
23. Wang YQ, Guo RD, Guo RM, Sheng W, Yin LR (2013) MicroRNA-182 promotes cell growth, invasion, and chemoresistance by targeting programmed cell death 4 (PDCD4) in human ovarian carcinomas. J Cell Biochem 114: 1464-1473.
24. Li J, Liang S, Jin H, Xu C, Ma D, et al. (2012) Tiam1, negatively regulated by miR-22, miR-183 and miR-31, is involved in migration, invasion and viability of ovarian cancer cells. Oncol Rep 27: 1835-1842.
25. Li XL, Hara T, Choi Y, Subramanian M, Francis P, et al. (2014) A p21-ZEB1 Complex Inhibits Epithelial-Mesenchymal Transition through the MicroRNA 183-96-182 Cluster. Mol Cell Biol 34: 533-550.
26. Kan CW, Hahn MA, Gard GB, Maidens J, Huh JY, et al. (2012) Elevated levels of circulating microRNA-200 family members correlate with serous epithelial ovarian cancer. BMC Cancer 12: 627.
27. Taylor DD, Gercel-Taylor C (2008) MicroRNA signatures of tumor-derived exosomes as diagnostic biomarkers of ovarian cancer. Gynecol Oncol 110: 13-21. (Pubitemid 351853251)