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Volumn 95, Issue 6, 2014, Pages 663-669

Integrating systems biology sources illuminates drug action

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

EID: 84901236897     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2014.51     Document Type: Article
Times cited : (22)

References (49)
  • 1
    • 84863085673 scopus 로고    scopus 로고
    • Multi-Target drugs: The trend of drug research and development
    • Lu, J.J., Pan, W., Hu, Y.J. & Wang, Y.T. Multi-Target drugs: The trend of drug research and development. PLoS One 7, e40262 (2012
    • (2012) PLoS One , vol.7
    • Lu, J.J.1    Pan, W.2    Hu, Y.J.3    Wang, Y.T.4
  • 2
    • 33644669581 scopus 로고    scopus 로고
    • Linking pathway gene expressions to the growth inhibition response from the national cancer institute's anticancer screen and drug mechanism of action
    • Huang, R., Wallqvist, A., Thanki, N. & Covell, D.G. Linking pathway gene expressions to the growth inhibition response from the National Cancer Institute's anticancer screen and drug mechanism of action. Pharmacogenomics J. 5, 381-399 (2005
    • (2005) Pharmacogenomics J. , vol.5 , pp. 381-399
    • Huang, R.1    Wallqvist, A.2    Thanki, N.3    Covell, D.G.4
  • 3
    • 79951976837 scopus 로고    scopus 로고
    • A sub-pathway-based approach for identifying drug response principal network
    • Chen, X. et al. A sub-pathway-based approach for identifying drug response principal network. Bioinformatics 27, 649-654 (2011
    • (2011) Bioinformatics , vol.27 , pp. 649-654
    • Chen, X.1
  • 4
    • 84862804815 scopus 로고    scopus 로고
    • A pathway profile-based method for drug repositioning
    • Ye, H., Yang, L., Cao, Z., Tang, K. & Li, Y. A pathway profile-based method for drug repositioning. Chinese Science Bulletin 57, 2106-12 (2012
    • (2012) Chinese Science Bulletin , vol.57 , pp. 2106-2112
    • Ye, H.1    Yang, L.2    Cao, Z.3    Tang, K.4    Li, Y.5
  • 6
    • 51649110496 scopus 로고    scopus 로고
    • A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose
    • Cooper, G.M. et al. A genome-wide scan for common genetic variants with a large influence on warfarin maintenance dose. Blood 112, 1022-1027 (2008
    • (2008) Blood , vol.112 , pp. 1022-1027
    • Cooper, G.M.1
  • 7
    • 84866415102 scopus 로고    scopus 로고
    • A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101
    • Baldwin, R.M. et al. A genome-wide association study identifies novel loci for paclitaxel-induced sensory peripheral neuropathy in CALGB 40101. Clin. Cancer Res. 18, 5099-5109 (2012
    • (2012) Clin. Cancer Res , vol.18 , pp. 5099-5109
    • Baldwin, R.M.1
  • 8
    • 84862908671 scopus 로고    scopus 로고
    • A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303
    • Innocenti, F. et al. A genome-wide association study of overall survival in pancreatic cancer patients treated with gemcitabine in CALGB 80303. Clin. Cancer Res. 18, 577-584 (2012
    • (2012) Clin. Cancer Res , vol.18 , pp. 577-584
    • Innocenti, F.1
  • 9
    • 84895862716 scopus 로고    scopus 로고
    • Automated detection of off-label drug use
    • Jung, K. et al. Automated detection of off-label drug use. PloS One, 9(2), e89324 (2014
    • (2014) PloS One , vol.9 , Issue.2
    • Jung, K.1
  • 10
    • 84864231551 scopus 로고    scopus 로고
    • INDI: A computational framework for inferring drug interactions and their associated recommendations
    • Gottlieb, A., Stein, G.Y., Oron, Y., Ruppin, E. & Sharan, R. INDI: A computational framework for inferring drug interactions and their associated recommendations. Mol. Syst. Biol. 8, 592 (2012
    • (2012) Mol. Syst. Biol , vol.8 , pp. 592
    • Gottlieb, A.1    Stein, G.Y.2    Oron, Y.3    Ruppin, E.4    Sharan, R.5
  • 11
    • 75549087817 scopus 로고    scopus 로고
    • An overview of the pubchem bioassay resource
    • Wang, Y. et al. An overview of the PubChem BioAssay resource. Nucleic Acids Res. 38, D255-D266 (2010
    • (2010) Nucleic Acids Res , vol.38
    • Wang, Y.1
  • 12
    • 0035142209 scopus 로고    scopus 로고
    • Conjugated equine estrogen improves glycemic control and blood lipoproteins in postmenopausal women with type 2 diabetes
    • Friday, K.E., Dong, C. & Fontenot, R.U. Conjugated equine estrogen improves glycemic control and blood lipoproteins in postmenopausal women with type 2 diabetes. J. Clin. Endocrinol. Metab. 86, 48-52 (2001
    • (2001) J. Clin. Endocrinol. Metab , vol.86 , pp. 48-52
    • Friday, K.E.1    Dong, C.2    Fontenot, R.U.3
  • 14
    • 84873531039 scopus 로고    scopus 로고
    • Long-Term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of ®-secretase in a mouse model of Alzheimer's disease
    • He, P., Cheng, X., Staufenbiel, M., Li, R. & Shen, Y. Long-Term treatment of thalidomide ameliorates amyloid-like pathology through inhibition of ®-secretase in a mouse model of Alzheimer's disease. PloS One 8, e55091 (2013
    • (2013) PloS One , vol.8
    • He, P.1    Cheng, X.2    Staufenbiel, M.3    Li, R.4    Shen, Y.5
  • 15
    • 0025998557 scopus 로고
    • Aspirin use and reduced risk of fatal colon cancer
    • Thun, M.J., Namboodiri, M.M. & Heath, C.W. Jr. Aspirin use and reduced risk of fatal colon cancer. N. Engl. J. Med. 325, 1593-1596 (1991
    • (1991) N. Engl. J. Med , vol.325 , pp. 1593-1596
    • Thun, M.J.1    Namboodiri, M.M.2    Heath Jr., C.W.3
  • 16
    • 0043075955 scopus 로고    scopus 로고
    • Rofecoxib (vioxx a specific cyclooxygenase-2 inhibitor, is chemopreventive in a mouse model of colon cancer
    • Evans, J.F. Rofecoxib (Vioxx), a specific cyclooxygenase-2 inhibitor, is chemopreventive in a mouse model of colon cancer. Am. J. Clin. Oncol. 26, S62-S65 (2003
    • (2003) Am. J. Clin. Oncol , vol.26
    • Evans, J.F.1
  • 17
    • 34548176264 scopus 로고    scopus 로고
    • Valproic acid for the treatment of myeloid malignancies
    • Kuendgen, A. & Gattermann, N. Valproic acid for the treatment of myeloid malignancies. Cancer 110, 943-954 (2007
    • (2007) Cancer , vol.110 , pp. 943-954
    • Kuendgen, A.1    Gattermann, N.2
  • 18
    • 16344371410 scopus 로고    scopus 로고
    • Acute leukemia associated with valproic acid treatment: A novel mechanism for leukemogenesis
    • Coyle, T.E., Bair, A.K., Stein, C., Vajpayee, N., Mehdi, S. & Wright, J. Acute leukemia associated with valproic acid treatment: A novel mechanism for leukemogenesis? Am. J. Hematol. 78, 256-260 (2005
    • (2005) Am. J. Hematol , vol.78 , pp. 256-260
    • Coyle, T.E.1    Bair, A.K.2    Stein, C.3    Vajpayee, N.4    Mehdi, S.5    Wright, J.6
  • 19
    • 0038637313 scopus 로고    scopus 로고
    • Lovastatin a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, induces apoptosis and differentiation in human anaplastic thyroid carcinoma cells
    • Wang, C.Y., Zhong, W.B., Chang, T.C., Lai, S.M. & Tsai, Y.F. Lovastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, induces apoptosis and differentiation in human anaplastic thyroid carcinoma cells. J. Clin. Endocrinol. Metab. 88, 3021-3026 (2003
    • (2003) J. Clin. Endocrinol. Metab , vol.88 , pp. 3021-3026
    • Wang, C.Y.1    Zhong, W.B.2    Chang, T.C.3    Lai, S.M.4    Tsai, Y.F.5
  • 20
    • 80255131406 scopus 로고    scopus 로고
    • Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the rho/rock-mediated pathway
    • Zhong, W.B., Hsu, S.P., Ho, P.Y., Liang, Y.C., Chang, T.C. & Lee, W.S. Lovastatin inhibits proliferation of anaplastic thyroid cancer cells through up-regulation of p27 by interfering with the Rho/ROCK-mediated pathway. Biochem. Pharmacol. 82, 1663-1672 (2011
    • (2011) Biochem. Pharmacol , vol.82 , pp. 1663-1672
    • Zhong, W.B.1    Hsu, S.P.2    Ho, P.Y.3    Liang, Y.C.4    Chang, T.C.5    Lee, W.S.6
  • 21
    • 0034202049 scopus 로고    scopus 로고
    • Development of thyroid follicular adenoma on simvastatin therapy
    • McCord, E.L. & Goenka, S. Development of thyroid follicular adenoma on simvastatin therapy. Tenn. Med. 93, 210-212 (2000
    • (2000) Tenn. Med , vol.93 , pp. 210-212
    • McCord, E.L.1    Goenka, S.2
  • 22
    • 77957179539 scopus 로고
    • Carcinogenicity and mutagenicity studies with fluvastatin, a new, entirely synthetic hmg-coa reductase inhibitor
    • Robison, R.L., Suter, W. & Cox, R.H. Carcinogenicity and mutagenicity studies with fluvastatin, a new, entirely synthetic HMG-CoA reductase inhibitor. Fundam. Appl. Toxicol. 23, 9-20 (1994
    • (1994) Fundam. Appl. Toxicol , vol.23 , pp. 9-20
    • Robison, R.L.1    Suter, W.2    Cox, R.H.3
  • 24
    • 8144225309 scopus 로고    scopus 로고
    • Aspirin-induced asthma: Clinical aspects, pathogenesis and management
    • Hamad, A.M., Sutcliffe, A.M. & Knox, A.J. Aspirin-induced asthma: Clinical aspects, pathogenesis and management. Drugs 64, 2417-2432 (2004
    • (2004) Drugs , vol.64 , pp. 2417-2432
    • Hamad, A.M.1    Sutcliffe, A.M.2    Knox, A.J.3
  • 25
    • 77955402131 scopus 로고    scopus 로고
    • Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: Meta-Analysis
    • Bolland, M.J. et al. Effect of calcium supplements on risk of myocardial infarction and cardiovascular events: Meta-Analysis. BMJ 341, c3691 (2010
    • (2010) BMJ , vol.341
    • Bolland, M.J.1
  • 26
    • 84873388732 scopus 로고    scopus 로고
    • Acute non-ST elevation myocardial infarction following paclitaxel administration for ovarian carcinoma: A case report and review of literature
    • Shah, K., Gupta, S., Ghosh, J., Bajpai, J. & Maheshwari, A. Acute non-ST elevation myocardial infarction following paclitaxel administration for ovarian carcinoma: A case report and review of literature. J. Cancer Res. Ther. 8, 442-444 (2012
    • (2012) J. Cancer Res. Ther , vol.8 , pp. 442-444
    • Shah, K.1    Gupta, S.2    Ghosh, J.3    Bajpai, J.4    Maheshwari, A.5
  • 27
    • 33847377573 scopus 로고    scopus 로고
    • A robustness-based approach to systems-oriented drug design
    • Kitano, H. A robustness-based approach to systems-oriented drug design. Nature Reviews Drug Discovery 5, 202-210 (2007
    • (2007) Nature Reviews Drug Discovery , vol.5 , pp. 202-210
    • Kitano, H.1
  • 28
    • 84877580262 scopus 로고    scopus 로고
    • Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review
    • Csermely, P., Korcsmáros, T., Kiss, H.J., London, G. & Nussinov, R. Structure and dynamics of molecular networks: A novel paradigm of drug discovery: A comprehensive review. Pharmacol Ther 138, 333-408 (2013
    • (2013) Pharmacol Ther , vol.138 , pp. 333-408
    • Csermely, P.1    Korcsmáros, T.2    Kiss, H.J.3    London, G.4    Nussinov, R.5
  • 29
    • 38549173606 scopus 로고    scopus 로고
    • The biogrid interaction database: 2008 update
    • Breitkreutz, B.J. et al. The BioGRID Interaction Database: 2008 update. Nucleic Acids Res. 36, D637-D640 (2008
    • (2008) Nucleic Acids Res , vol.36
    • Breitkreutz, B.J.1
  • 30
    • 0036088133 scopus 로고    scopus 로고
    • Dip the database of interacting proteins: A research tool for studying cellular networks of protein interactions
    • Xenarios, I., Salwínski, L., Duan, X.J., Higney, P., Kim, S.M. & Eisenberg, D. DIP, the Database of Interacting Proteins: A research tool for studying cellular networks of protein interactions. Nucleic Acids Res. 30, 303-305 (2002
    • (2002) Nucleic Acids Res , vol.30 , pp. 303-305
    • Xenarios, I.1    Salwínski, L.2    Duan, X.J.3    Higney, P.4    Kim, S.M.5    Eisenberg, D.6
  • 31
    • 58149193222 scopus 로고    scopus 로고
    • Human protein reference database-2009 update
    • Prasad, T.S.K. et al. Human protein reference database-2009 update. Nucleic Acids Res 37, D767-D72 (2009
    • (2009) Nucleic Acids Res , vol.37
    • Prasad, T.S.K.1
  • 32
    • 84859204939 scopus 로고    scopus 로고
    • The IntAct molecular interaction database in 2012
    • Kerrien, S. et al. The IntAct molecular interaction database in 2012. Nucleic Acids Res. 40, D841-D846 (2012
    • (2012) Nucleic Acids Res , vol.40
    • Kerrien, S.1
  • 33
    • 33846073818 scopus 로고    scopus 로고
    • Mint: The molecular interaction database
    • Chatr-Aryamontri, A. et al. MINT: The Molecular INTeraction database. Nucleic Acids Res. 35, D572-D574 (2007
    • (2007) Nucleic Acids Res , vol.35
    • Chatr-Aryamontri, A.1
  • 34
    • 0036081347 scopus 로고    scopus 로고
    • MIPS: A database for genomes and protein sequences
    • Mewes, H.W. et al. MIPS: A database for genomes and protein sequences. Nucleic Acids Res. 30, 31-34 (2002
    • (2002) Nucleic Acids Res , vol.30 , pp. 31-34
    • Mewes, H.W.1
  • 36
    • 75549090213 scopus 로고    scopus 로고
    • Kegg for representation and analysis of molecular networks involving diseases and drugs
    • Kanehisa, M., Goto, S., Furumichi, M., Tanabe, M. & Hirakawa, M. KEGG for representation and analysis of molecular networks involving diseases and drugs. Nucleic Acids Res. 38, D355-D360 (2010
    • (2010) Nucleic Acids Res , vol.38
    • Kanehisa, M.1    Goto, S.2    Furumichi, M.3    Tanabe, M.4    Hirakawa, M.5
  • 37
    • 77957243164 scopus 로고    scopus 로고
    • Chea: Transcription factor regulation inferred from integrating genome-wide chip-x experiments
    • Lachmann, A., Xu, H., Krishnan, J., Berger, S.I., Mazloom, A.R. & Máayan, A. ChEA: Transcription factor regulation inferred from integrating genome-wide ChIP-X experiments. Bioinformatics 26, 2438-2444 (2010
    • (2010) Bioinformatics , vol.26 , pp. 2438-2444
    • Lachmann, A.1    Xu, H.2    Krishnan, J.3    Berger, S.I.4    Mazloom, A.R.5    Máayan, A.6
  • 38
    • 58149186477 scopus 로고    scopus 로고
    • Pid: The pathway interaction database
    • Schaefer, C.F. et al. PID: The Pathway Interaction Database. Nucleic Acids Res. 37, D674-D679 (2009
    • (2009) Nucleic Acids Res , vol.37
    • Schaefer, C.F.1
  • 39
    • 58149177166 scopus 로고    scopus 로고
    • Reactome knowledgebase of human biological pathways and processes
    • Matthews, L. et al. Reactome knowledgebase of human biological pathways and processes. Nucleic Acids Res. 37, D619-D622 (2009
    • (2009) Nucleic Acids Res , vol.37
    • Matthews, L.1
  • 41
    • 0035755351 scopus 로고    scopus 로고
    • Integrating genotype and phenotype information: An overview of the pharmgkb project pharmacogenetics research network and knowledge base
    • Klein, T.E. et al. Integrating genotype and phenotype information: An overview of the PharmGKB project. Pharmacogenetics Research Network and Knowledge Base. Pharmacogenomics J. 1, 167-170 (2001
    • (2001) Pharmacogenomics J. , vol.1 , pp. 167-170
    • Klein, T.E.1
  • 42
    • 38549151817 scopus 로고    scopus 로고
    • Drugbank: A knowledgebase for drugs, drug actions and drug targets
    • Wishart, D.S. et al. DrugBank: A knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 36, D901-D906 (2008
    • (2008) Nucleic Acids Res , vol.36
    • Wishart, D.S.1
  • 43
    • 0035998736 scopus 로고    scopus 로고
    • Online mendelian inheritance in man (omim), a knowledgebase of human genes and genetic disorders
    • Hamosh, A., Scott, A.F., Amberger, J., Bocchini, C., Valle, D. & McKusick, V.A. Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res. 30, 52-55 (2002
    • (2002) Nucleic Acids Res , vol.30 , pp. 52-55
    • Hamosh, A.1    Scott, A.F.2    Amberger, J.3    Bocchini, C.4    Valle, D.5    McKusick, V.A.6
  • 44
    • 79958754253 scopus 로고    scopus 로고
    • Predict: A method for inferring novel drug indications with application to personalized medicine
    • Gottlieb, A., Stein, G.Y., Ruppin, E. & Sharan, R. PREDICT: A method for inferring novel drug indications with application to personalized medicine. Mol. Syst. Biol. 7, 496 (2011
    • (2011) Mol. Syst. Biol , vol.7 , pp. 496
    • Gottlieb, A.1    Stein, G.Y.2    Ruppin, E.3    Sharan, R.4
  • 47
    • 0000210258 scopus 로고
    • Nouvelles recherches sur la distribution florale
    • Jaccard, P. Nouvelles recherches sur la distribution florale. Bul Soc Vaudoise Sci Nat 44, 223-270 (1908
    • (1908) Bul Soc Vaudoise Sci Nat , vol.44 , pp. 223-270
    • Jaccard, P.1
  • 49
    • 0345863927 scopus 로고    scopus 로고
    • The unified medical language system (umls): Integrating biomedical terminology
    • Bodenreider, O. The Unified Medical Language System (UMLS): Integrating biomedical terminology. Nucleic Acids Res. 32, D267-D270 (2004
    • (2004) Nucleic Acids Res , vol.32
    • Bodenreider, O.1


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