Inhibition of Egr1 expression underlies the anti-mitogenic effects of cAMP in vascular smooth muscle cells

Journal of Molecular and Cellular Cardiology

Volumn 72, Issue , 2014, Pages 9-19

  Kimura, Tomomi E ^a   Duggirala, Aparna ^a   Hindmarch, Charles C T ^a,c   Hewer, Richard C ^a   Cui, Mei Zhen ^b   Newby, Andrew C ^a   Bond, Mark ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b UNIVERSITY OF TENNESSEE   (United States)

^c UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

3' 5' Cyclic adenosine monophosphate; Early growth response gene 1; Exchange protein activated by cAMP; Serum response factor; Zif268

Indexed keywords

ADENOSINE; ADENOSINE A2 RECEPTOR AGONIST; CICAPROST; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EARLY GROWTH RESPONSE FACTOR 1; EXCHANGE PROTEIN ACTIVATED BY CAMP; FORSKOLIN; GUANINE NUCLEOTIDE EXCHANGE FACTOR; MAL PROTEIN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; RAC1 PROTEIN; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR ELK 1; TRANSCRIPTION FACTOR ELK 4; UNCLASSIFIED DRUG; AMINOPYRIDINE DERIVATIVE; BAY 60-6583; EGR1 PROTEIN, HUMAN; EGR1 PROTEIN, RAT; ELK1 PROTEIN, RAT; EPAC PROTEIN, RAT; PROSTACYCLIN; PROTEIN BINDING; RAPGEF3 PROTEIN, HUMAN; SRF PROTEIN, HUMAN;

ACTIN FILAMENT; ANIMAL CELL; ARTICLE; CELL NUCLEUS; CELL PROLIFERATION; CONTROLLED STUDY; ENDOTHELIUM CELL; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SERUM RESPONSIVE ELEMENT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE CELL; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; ANTIBODY SPECIFICITY; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULAR SMOOTH MUSCLE;

ADENOSINE; AMINOPYRIDINES; ANIMALS; CELL PROLIFERATION; COLFORSIN; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; EARLY GROWTH RESPONSE PROTEIN 1; EPOPROSTENOL; ETS-DOMAIN PROTEIN ELK-1; GENE EXPRESSION REGULATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; MALE; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; ORGAN SPECIFICITY; PRIMARY CELL CULTURE; PROTEIN BINDING; RAC1 GTP-BINDING PROTEIN; RATS; RATS, SPRAGUE-DAWLEY; SERUM RESPONSE FACTOR; SIGNAL TRANSDUCTION;

EID: 84901228736     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2014.02.001     Document Type: Article

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