Glucocorticoid regulates TrkB protein levels via c-Cbl dependent ubiquitination: A decrease in c-Cbl mRNA in the prefrontal cortex of suicide subjects

Psychoneuroendocrinology

Volumn 45, Issue , 2014, Pages 108-118

  Pandya, Chirayu ^a   Kutiyanawalla, Ammar ^a   Turecki, Gustavo ^b   Pillai, Anilkumar ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

C Cbl; Glucocorticoid; Neurons; Suicide; TrkB; Ubiquitination

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CBL PROTEIN; CORTICOSTERONE; GLUCOCORTICOID RECEPTOR; MESSENGER RNA; PROTEASOME INHIBITOR; PROTEIN TYROSINE KINASE; UBIQUITIN PROTEIN LIGASE E3; GLUCOCORTICOID;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME BINDING; HIPPOCAMPUS; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LONG TERM EXPOSURE; MALE; MOUSE; NERVE CELL PLASTICITY; NONHUMAN; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DOMAIN; PROTEIN STABILITY; REGULATORY MECHANISM; SUICIDE; UBIQUITINATION; UPREGULATION; ANIMAL; ANIMAL EMBRYO; AUTOPSY; DRUG EFFECTS; GENETICS; METABOLISM; MIDDLE AGED; NEWBORN; PATHOLOGY; PROTEIN PROCESSING; YOUNG ADULT;

ADULT; ANIMALS; ANIMALS, NEWBORN; AUTOPSY; CORTICOSTERONE; EMBRYO, MAMMALIAN; GLUCOCORTICOIDS; HUMANS; MALE; MICE; MIDDLE AGED; PREFRONTAL CORTEX; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTO-ONCOGENE PROTEINS C-CBL; RECEPTOR, TRKB; RNA, MESSENGER; SUICIDE; UBIQUITINATION; YOUNG ADULT;

EID: 84901203254     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2014.03.020     Document Type: Article

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