-
1
-
-
77958488277
-
Engineering the perfect (bacterial) cancer therapy
-
Forbes NS,. Engineering the perfect (bacterial) cancer therapy. Nat Rev Cancer 2010; 10: 785-94.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 785-794
-
-
Forbes, N.S.1
-
2
-
-
77956484714
-
Salmonella-allies in the fight against cancer
-
Leschner S, Weiss S,. Salmonella-allies in the fight against cancer. J Mol Med (Berlin, Germany) 2010; 88: 763-73.
-
(2010)
J Mol Med (Berlin, Germany)
, vol.88
, pp. 763-773
-
-
Leschner, S.1
Weiss, S.2
-
3
-
-
0036140068
-
Phase i study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma
-
et al.
-
Toso JF, Gill VJ, Hwu P, et al. Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma. J Clin Oncol 2002; 20: 142-52.
-
(2002)
J Clin Oncol
, vol.20
, pp. 142-152
-
-
Toso, J.F.1
Gill, V.J.2
Hwu, P.3
-
4
-
-
0037336216
-
Continuous intravenous administration of live genetically modified Salmonella typhimurium in patients with metastatic melanoma
-
Heimann DM, Rosenberg SA,. Continuous intravenous administration of live genetically modified Salmonella typhimurium in patients with metastatic melanoma. J. Immunother. 2003; 26: 179-80.
-
(2003)
J. Immunother.
, vol.26
, pp. 179-180
-
-
Heimann, D.M.1
Rosenberg, S.A.2
-
5
-
-
12444302834
-
Pilot trial of genetically modified, attenuated Salmonella expressing the E. Coli cytosine deaminase gene in refractory cancer patients
-
et al.
-
Nemunaitis J, Cunningham C, Senzer N, et al. Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients. Cancer Gene Ther. 2003; 10: 737-44.
-
(2003)
Cancer Gene Ther
, vol.10
, pp. 737-744
-
-
Nemunaitis, J.1
Cunningham, C.2
Senzer, N.3
-
6
-
-
0030854392
-
Tumor-targeted Salmonella as a novel anticancer vector
-
Pawelek JM, Low KB, Bermudes D,. Tumor-targeted Salmonella as a novel anticancer vector. Cancer Res. 1997; 57: 4537-44.
-
(1997)
Cancer Res
, vol.57
, pp. 4537-4544
-
-
Pawelek, J.M.1
Low, K.B.2
Bermudes, D.3
-
7
-
-
0141482164
-
Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors
-
et al.
-
Forbes NS, Munn LL, Fukumura D, et al. Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors. Cancer Res. 2003; 63: 5188-93.
-
(2003)
Cancer Res
, vol.63
, pp. 5188-5193
-
-
Forbes, N.S.1
Munn, L.L.2
Fukumura, D.3
-
8
-
-
70449533849
-
Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice
-
Ganai S, Arenas RB, Forbes NS,. Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice. Br J Cancer 2009; 101: 1683-91.
-
(2009)
Br J Cancer
, vol.101
, pp. 1683-1691
-
-
Ganai, S.1
Arenas, R.B.2
Forbes, N.S.3
-
9
-
-
49449116738
-
Inhibition of tumor growth using Salmonella expressing Fas ligand
-
et al.
-
Loeffler M, Le'Negrate G, Krajewska M, et al. Inhibition of tumor growth using Salmonella expressing Fas ligand. J Natl Cancer Inst 2008; 100: 1113-16.
-
(2008)
J Natl Cancer Inst
, vol.100
, pp. 1113-1116
-
-
Loeffler, M.1
Le'Negrate, G.2
Krajewska, M.3
-
10
-
-
62549130694
-
Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors
-
et al.
-
Ryan RM, Green J, Williams PJ, et al. Bacterial delivery of a novel cytolysin to hypoxic areas of solid tumors. Gene Ther. 2009; 16: 329-39.
-
(2009)
Gene Ther.
, vol.16
, pp. 329-339
-
-
Ryan, R.M.1
Green, J.2
Williams, P.J.3
-
11
-
-
34547865745
-
Attenuated Salmonella engineered to produce human cytokine LIGHT inhibit tumor growth
-
et al.
-
Loeffler M, Le'Negrate G, Krajewska M, et al. Attenuated Salmonella engineered to produce human cytokine LIGHT inhibit tumor growth. Proc Natl Acad Sci USA 2007; 104: 12879-83.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 12879-12883
-
-
Loeffler, M.1
Le'Negrate, G.2
Krajewska, M.3
-
12
-
-
57149083657
-
Potent anti-tumor activity of systemically-administered IL2-expressing Salmonella correlates with decreased angiogenesis and enhanced tumor apoptosis
-
et al.
-
Al-Ramadi BK, Fernandez-Cabezudo MJ, El-Hasasna H, et al. Potent anti-tumor activity of systemically-administered IL2-expressing Salmonella correlates with decreased angiogenesis and enhanced tumor apoptosis. Clin Immunol (Orlando, FL) 2009; 130: 89-97.
-
(2009)
Clin Immunol (Orlando, FL)
, vol.130
, pp. 89-97
-
-
Al-Ramadi, B.K.1
Fernandez-Cabezudo, M.J.2
El-Hasasna, H.3
-
13
-
-
78449281712
-
Monotherapy with a tumor-targeting mutant of S. Typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer
-
et al.
-
Yam C, Zhao M, Hayashi K, et al. Monotherapy with a tumor-targeting mutant of S. typhimurium inhibits liver metastasis in a mouse model of pancreatic cancer. J Surg Res 2010; 164: 248-55.
-
(2010)
J Surg Res
, vol.164
, pp. 248-255
-
-
Yam, C.1
Zhao, M.2
Hayashi, K.3
-
14
-
-
2342431730
-
Intractable cancers: The many faces of multidrug resistance and the many targets it presents for therapeutic attack
-
Stein WD, Bates SE, Fojo T,. Intractable cancers: The many faces of multidrug resistance and the many targets it presents for therapeutic attack. Curr Drug Targets 2004; 5: 333-46.
-
(2004)
Curr Drug Targets
, vol.5
, pp. 333-346
-
-
Stein, W.D.1
Bates, S.E.2
Fojo, T.3
-
16
-
-
79959380538
-
In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis
-
et al.
-
Ganai S, Arenas RB, Sauer JP, et al. In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis. Cancer Gene Ther 2011; 18: 457-66.
-
(2011)
Cancer Gene Ther
, vol.18
, pp. 457-466
-
-
Ganai, S.1
Arenas, R.B.2
Sauer, J.P.3
-
17
-
-
33745744210
-
Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro
-
Kasinskas RW, Forbes NS,. Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro. Biotechnol Bioeng 2006; 94: 710-21.
-
(2006)
Biotechnol Bioeng
, vol.94
, pp. 710-721
-
-
Kasinskas, R.W.1
Forbes, N.S.2
-
18
-
-
34248195085
-
Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis
-
Kasinskas RW, Forbes NS,. Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis. Cancer Res 2007; 67: 3201-9.
-
(2007)
Cancer Res
, vol.67
, pp. 3201-3209
-
-
Kasinskas, R.W.1
Forbes, N.S.2
-
19
-
-
84856710443
-
Motility is critical for effective distribution and accumulation of bacteria in tumor tissue
-
Toley BJ, Forbes NS,. Motility is critical for effective distribution and accumulation of bacteria in tumor tissue. Integr Biol (Camb) 2012; 4: 165-76.
-
(2012)
Integr Biol (Camb)
, vol.4
, pp. 165-176
-
-
Toley, B.J.1
Forbes, N.S.2
-
20
-
-
69249131376
-
Tumor invasion of Salmonella enterica serovar Typhimurium is accompanied by strong hemorrhage promoted by TNF-alpha
-
et al.
-
Leschner S, Westphal K, Dietrich N, et al. Tumor invasion of Salmonella enterica serovar Typhimurium is accompanied by strong hemorrhage promoted by TNF-alpha. PLoS One 2009; 4: e6692.
-
(2009)
PLoS One
, vol.4
-
-
Leschner, S.1
Westphal, K.2
Dietrich, N.3
-
21
-
-
79955046293
-
Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium
-
Crull K, Bumann D, Weiss S,. Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium. FEMS Immunol Med Microbiol 2011; 62: 75-83.
-
(2011)
FEMS Immunol Med Microbiol
, vol.62
, pp. 75-83
-
-
Crull, K.1
Bumann, D.2
Weiss, S.3
-
22
-
-
0038447123
-
Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock
-
Van Amersfoort ES, Van Berkel TJC, Kuiper J,. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin Microbiol Rev 2003; 16: 379-414.
-
(2003)
Clin Microbiol Rev
, vol.16
, pp. 379-414
-
-
Van Amersfoort, E.S.1
Van Berkel, T.J.C.2
Kuiper, J.3
-
23
-
-
22944443625
-
Molecular mechanisms involved in the pathogenesis of septic shock
-
Lõpez-Bojõrquez LN, Dehesa AZ, Reyes-Terán G,. Molecular mechanisms involved in the pathogenesis of septic shock. Arch Med Res 2004; 35: 465-79.
-
(2004)
Arch Med Res
, vol.35
, pp. 465-479
-
-
Lõpez-Bojõrquez, L.N.1
Dehesa, A.Z.2
Reyes-Terán, G.3
-
24
-
-
0032728550
-
Escherichia coli msbB gene as a virulence factor and a therapeutic target
-
Somerville JE, Jr, Cassiano L, Darveau RP,. Escherichia coli msbB gene as a virulence factor and a therapeutic target. Infect Immun 1999; 67: 6583-90.
-
(1999)
Infect Immun
, vol.67
, pp. 6583-6590
-
-
Somerville, Jr.J.E.1
Cassiano, L.2
Darveau, R.P.3
-
25
-
-
15444341308
-
A lethal role for lipid A in Salmonella infections
-
et al.
-
Khan SA, Everest P, Servos S, et al. A lethal role for lipid A in Salmonella infections. Mol Microbiol 1998; 29: 571-79.
-
(1998)
Mol Microbiol
, vol.29
, pp. 571-579
-
-
Khan, S.A.1
Everest, P.2
Servos, S.3
-
26
-
-
0032927753
-
Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo
-
et al.
-
Low KB, Ittensohn M, Le T, et al. Lipid A mutant Salmonella with suppressed virulence and TNFalpha induction retain tumor-targeting in vivo. Nat Biotechnol 1999; 17: 37-41.
-
(1999)
Nat Biotechnol
, vol.17
, pp. 37-41
-
-
Low, K.B.1
Ittensohn, M.2
Le, T.3
-
27
-
-
0034088909
-
Biodistribution and genetic stability of the novel antitumor agent VNP20009, a genetically modified strain of Salmonella typhimurium
-
et al.
-
Clairmont C, Lee KC, Pike J, et al. Biodistribution and genetic stability of the novel antitumor agent VNP20009, a genetically modified strain of Salmonella typhimurium. J Infect Dis 2000; 181: 1996-2002.
-
(2000)
J Infect Dis
, vol.181
, pp. 1996-2002
-
-
Clairmont, C.1
Lee, K.C.2
Pike, J.3
-
29
-
-
27644526910
-
Systemic administration of an attenuated, tumor-targeting Salmonella typhimurium to dogs with spontaneous neoplasia: Phase i evaluation
-
et al.
-
Thamm DH, Kurzman ID, King I, et al. Systemic administration of an attenuated, tumor-targeting Salmonella typhimurium to dogs with spontaneous neoplasia: Phase I evaluation. Clin Cancer Res 2005; 11: 4827-34.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 4827-4834
-
-
Thamm, D.H.1
Kurzman, I.D.2
King, I.3
-
30
-
-
12944335180
-
Comparative evaluation of the acute toxic effects in monkeys, pigs and mice of a genetically engineered Salmonella strain (VNP20009) being developed as an antitumor agent
-
et al.
-
Lee KC, Zheng LM, Luo X, et al. Comparative evaluation of the acute toxic effects in monkeys, pigs and mice of a genetically engineered Salmonella strain (VNP20009) being developed as an antitumor agent. Int J Toxicol 2000; 19: 19-25.
-
(2000)
Int J Toxicol
, vol.19
, pp. 19-25
-
-
Lee, K.C.1
Zheng, L.M.2
Luo, X.3
-
31
-
-
12544254834
-
Acute inflammatory response to endotoxin in mice and humans
-
et al.
-
Copeland S, Warren HS, Lowry SF, et al Acute inflammatory response to endotoxin in mice and humans. Clin Diagn Lab Immun 2005; 12: 60-7.
-
(2005)
Clin Diagn Lab Immun
, vol.12
, pp. 60-67
-
-
Copeland, S.1
Warren, H.S.2
Lowry, S.F.3
-
32
-
-
0028873514
-
Increased circulating cytokines, cytokine antagonists, and E-selectin after intravenous administration of endotoxin in humans
-
Kuhns DB, Alvord WG, Gallin JI,. Increased circulating cytokines, cytokine antagonists, and E-selectin after intravenous administration of endotoxin in humans. J Infect Dis 1995; 171: 145-52.
-
(1995)
J Infect Dis
, vol.171
, pp. 145-152
-
-
Kuhns, D.B.1
Alvord, W.G.2
Gallin, J.I.3
-
33
-
-
0035670213
-
Differential clearance and induction of host responses by various administered or released lipopolysaccharides
-
et al.
-
Hasunuma R, Morita H, Tanaka S, et al. Differential clearance and induction of host responses by various administered or released lipopolysaccharides. J Endotoxin Res 2001; 7: 421-29.
-
(2001)
J Endotoxin Res
, vol.7
, pp. 421-429
-
-
Hasunuma, R.1
Morita, H.2
Tanaka, S.3
-
34
-
-
80052841941
-
A systems approach for tumor pharmacokinetics
-
Thurber GM, Weissleder R,. A systems approach for tumor pharmacokinetics. PLoS One 2011; 6: e24696.
-
(2011)
PLoS One
, vol.6
-
-
Thurber, G.M.1
Weissleder, R.2
-
35
-
-
40849145522
-
Plasmid-borne prokaryotic gene expression: Sources of variability and quantitative system characterization
-
et al.
-
Bagh S, Mazumder M, Velauthapillai T, et al. Plasmid-borne prokaryotic gene expression: Sources of variability and quantitative system characterization. Phys Rev E 2008; 77: 021919.
-
(2008)
Phys Rev e
, vol.77
, pp. 021919
-
-
Bagh, S.1
Mazumder, M.2
Velauthapillai, T.3
-
36
-
-
44749086924
-
Integrating cell-cycle progression, drug penetration and energy metabolism to identify improved cancer therapeutic strategies
-
Venkatasubramanian R, Henson MA, Forbes NS,. Integrating cell-cycle progression, drug penetration and energy metabolism to identify improved cancer therapeutic strategies. J Theor Biol 2008; 253: 98-117.
-
(2008)
J Theor Biol
, vol.253
, pp. 98-117
-
-
Venkatasubramanian, R.1
Henson, M.A.2
Forbes, N.S.3
-
37
-
-
14144251067
-
Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium
-
et al.
-
Zhao M, Yang M, Li X-M, et al. Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium. Proc Natl Acad Sci USA 2005; 102: 755-60.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 755-760
-
-
Zhao, M.1
Yang, M.2
Li, X.-M.3
-
38
-
-
35148881028
-
Drug resistance and the solid tumor microenvironment
-
et al.
-
Trédan O, Galmarini CM, Patel K, et al. Drug resistance and the solid tumor microenvironment. J Natl Cancer Inst 2007; 99: 1441-54.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1441-1454
-
-
Trédan, O.1
Galmarini, C.M.2
Patel, K.3
-
39
-
-
34547121206
-
Hypoxia in cancer: Significance and impact on clinical outcome
-
Vaupel P, Mayer A,. Hypoxia in cancer: Significance and impact on clinical outcome. Cancer Metastasis Rev 2007; 26: 225-39.
-
(2007)
Cancer Metastasis Rev
, vol.26
, pp. 225-239
-
-
Vaupel, P.1
Mayer, A.2
-
40
-
-
0034475164
-
Tumor-targeted Salmonella-Highly selective delivery vectors
-
Bermudes D, Low B, Pawelek J,. Tumor-targeted Salmonella-Highly selective delivery vectors. Cancer Gene Ther 2000; 465: 57-63.
-
(2000)
Cancer Gene Ther
, vol.465
, pp. 57-63
-
-
Bermudes, D.1
Low, B.2
Pawelek, J.3
-
41
-
-
0026568118
-
Cytokine production after intravenous or peritoneal Gram-negative bacterial challenge in mice-Comparative protective efficacy of antibodies to tumor-necrosis-factor-alpha and to lipopolysaccharide
-
et al.
-
Zanetti G, Heumann D, Gerain J, et al. Cytokine production after intravenous or peritoneal Gram-negative bacterial challenge in mice-Comparative protective efficacy of antibodies to tumor-necrosis-factor-alpha and to lipopolysaccharide. J Immunol 1992; 148: 1890-97.
-
(1992)
J Immunol
, vol.148
, pp. 1890-1897
-
-
Zanetti, G.1
Heumann, D.2
Gerain, J.3
|