Motility is critical for effective distribution and accumulation of bacteria in tumor tissue

Integrative Biology

Volumn 4, Issue 2, 2012, Pages 165-176

  Toley, Bhushan J ^a   Forbes, Neil S ^a  

^a University of Massachusetts   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 DIFLUOROMETHOXY 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL] 4 OXO 3 QUINOLINECARBOXYLIC ACID;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BIOACCUMULATION; COLONY FORMING UNIT; ESCHERICHIA COLI; IN VITRO STUDY; MATHEMATICAL MODEL; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SOLID TUMOR;

ADENOCARCINOMA; APOPTOSIS; CELL LINE, TUMOR; COLONY COUNT, MICROBIAL; COLORECTAL NEOPLASMS; ESCHERICHIA COLI; HUMANS; MICROFLUIDIC ANALYTICAL TECHNIQUES; MICROSCOPY, FLUORESCENCE; MODELS, BIOLOGICAL; NEOVASCULARIZATION, PATHOLOGIC; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 84856710443     PISSN: 17579694     EISSN: 17579708     Source Type: Journal    
DOI: 10.1039/c2ib00091a     Document Type: Article

References (51)

1. D. S. Cowan I. F. Tannock Factors that influence the penetration of methotrexate through solid tissue Int. J. Cancer 2001 91 120 125
2. A. J. Davis I. F. Tannock Tumor physiology and resistance to chemotherapy: repopulation and drug penetration Cancer Treat. Res. 112 1 26
3. A. I. Minchinton I. F. Tannock Drug penetration in solid tumours Nat. Rev. Cancer 2006 6 583 592 (Pubitemid 44140857)
4. I. F. Tannock Tumor physiology and drug resistance Cancer Metastasis Rev. 2001 20 123 132 (Pubitemid 34074688)
5. R. W. Kasinskas N. S. Forbes Salmonella typhimurium specifically chemotax and proliferate in heterogeneous tumor tissue in vitro Biotechnol. Bioeng. 2006 94 710 721 (Pubitemid 44014201)
6. R. W. Kasinskas N. S. Forbes Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis Cancer Res. 2007 67 3201 3209 (Pubitemid 46724858)
7. G. Alexandre S. Greer-Phillips I. B. Zhulin Ecological role of energy taxis in microorganisms FEMS Microbiol. Rev. 2004 28 113 126 (Pubitemid 38224510)
8. J. M. Pawelek K. B. Low D. Bermudes Tumor-targeted Salmonella as a novel anticancer vector Cancer Res. 1997 57 4537 4544 (Pubitemid 27441058)
9. Y. A. Yu S. Shabahang T. M. Timiryasova Q. Zhang R. Beltz I. Gentschev W. Goebel A. A. Szalay Visualization of tumors and metastases in live animals with bacteria and vaccinia virus encoding light-emitting proteins Nat. Biotechnol. 2004 22 313 320 (Pubitemid 38295764)
10. R. C. Parker H. C. Plummer et al., Effect of histolyticus infection and toxin on transplantable mouse tumors Proc. Soc. Exp. Biol. Med. 1947 66 461 467
11. Y. Kohwi K. Imai Z. Tamura Y. Hashimoto Antitumor effect of Bifidobacterium infantis in mice Gann@ 1978 69 613 618 (Pubitemid 9064809)
12. S. J. Barnett L. J. Soto 3rd B. S. Sorenson B. W. Nelson A. S. Leonard D. A. Saltzman Attenuated Salmonella typhimurium invades and decreases tumor burden in neuroblastoma J. Pediatr. Surg. 2005 40 993 997
13. J. J. Min H. J. Kim J. H. Park S. Moon J. H. Jeong Y. J. Hong K. O. Cho J. H. Nam N. Kim Y. K. Park H. S. Bom J. H. Rhee H. E. Choy Noninvasive real-time imaging of tumors and metastases using tumor-targeting light-emitting Escherichia coli Mol. Imaging Biol. 2008 10 54 61
14. N. S. Forbes L. L. Munn D. Fukumura R. K. Jain Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors Cancer Res. 2003 63 5188 5193 (Pubitemid 37139825)
15. C. Nagakura K. Hayashi M. Zhao K. Yamauchi N. Yamamoto H. Tsuchiya K. Tomita M. Bouvet R. M. Hoffman Efficacy of a genetically-modified Salmonella typhimurium in an orthotopic human pancreatic cancer in nude mice Anticancer Res. 2009 29 1873 1878
16. N. S. Forbes Engineering the perfect (bacterial) cancer therapy Nat. Rev. Cancer 2010 10 785 794
17. S. Ganai R. B. Arenas N. S. Forbes Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice Br. J. Cancer 2009 101 1683 1691
18. J. Stritzker S. Weibel P. J. Hill T. A. Oelschlaeger W. Goebel A. A. Szalay Tumor-specific colonization, tissue distribution, and gene induction by probiotic Escherichia coli Nissle 1917 in live mice Int. J. Med. Microbiol. 2007 297 151 162 (Pubitemid 46678925)
19. K. B. Low M. Ittensohn T. Le J. Platt S. Sodi M. Amoss O. Ash E. Carmichael A. Chakraborty J. Fischer S. L. Lin X. Luo S. I. Miller L. Zheng I. King J. M. Pawelek D. Bermudes Lipid A mutant Salmonella with suppressed virulence and TNF alpha induction retain tumor-targeting in vivo Nat. Biotechnol. 1999 17 37 41 (Pubitemid 29037207)
20. S. Weibel J. Stritzker M. Eck W. Goebel A. A. Szalay Colonization of experimental murine breast tumours by Escherichia coli K-12 significantly alters the tumour microenvironment Cell. Microbiol. 2008 10 1235 1248 (Pubitemid 351663917)
21. H. Y. Zhang J. H. Man B. Liang T. Zhou C. H. Wang T. Li H. Y. Li W. H. Li B. F. Jin P. J. Zhang J. Zhao X. Pan K. He W. L. Gong X. M. Zhang A. L. Li Tumor-targeted delivery of biologically active TRAIL protein Cancer Gene Ther. 2010 17 334 343
22. K. Westphal S. Leschner J. Jablonska H. Loessner S. Weiss Containment of tumor-colonizing bacteria by host neutrophils Cancer Res. 2008 68 2952 2960 (Pubitemid 351556296)
23. L. H. Dang C. Bettegowda D. L. Huso K. W. Kinzler B. Vogelstein Combination bacteriolytic therapy for the treatment of experimental tumors Proc. Natl. Acad. Sci. U. S. A. 2001 98 15155 15160 (Pubitemid 34013985)
24. D. M. Heimann S. A. Rosenberg Continuous intravenous administration of live genetically modified Salmonella typhimurium in patients with metastatic melanoma J. Immunother. 2003 26 179 180 (Pubitemid 36292789)
25. J. F. Toso V. J. Gill P. Hwu F. M. Marincola N. P. Restifo D. J. Schwartzentruber R. M. Sherry S. L. Topalian J. C. Yang F. Stock L. J. Freezer K. E. Morton C. Seipp L. Haworth S. Mavroukakis D. White S. MacDonald J. Mao M. Sznol S. A. Rosenberg Phase I study of the intravenous administration of attenuated Salmonella typhimurium to patients with metastatic melanoma J. Clin. Oncol. 2002 20 142 152 (Pubitemid 34032605)
26. J. Nemunaitis C. Cunningham N. Senzer J. Kuhn J. Cramm C. Litz R. Cavagnolo A. Cahill C. Clairmont M. Sznol Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients Cancer Gene Ther. 2003 10 737 744 (Pubitemid 37243794)
27. M. Zhao M. Yang X. M. Li P. Jiang E. Baranov S. Li M. Xu S. Penman R. M. Hoffman Tumor-targeting bacterial therapy with amino acid auxotrophs of GFP-expressing Salmonella typhimurium Proc. Natl. Acad. Sci. U. S. A. 2005 102 755 760 (Pubitemid 40282738)
28. A. T. St Jean M. Zhang N. S. Forbes Bacterial therapies: completing the cancer treatment toolbox Curr. Opin. Biotechnol. 2008 19 511 517
29. K. A. Eaton D. R. Morgan S. Krakowka Campylobacter pylori virulence factors in gnotobiotic piglets Infect. Immun. 1989 57 1119 1125 (Pubitemid 19087856)
30. K. M. Ottemann J. F. Miller Roles for motility in bacterial-host interactions Mol. Microbiol. 1997 24 1109 1117 (Pubitemid 27293786)
31. S. Moens J. Vanderleyden Functions of bacterial flagella Crit. Rev. Microbiol. 1996 22 67 100 (Pubitemid 26249483)
32. R. Lux J. N. Miller N. H. Park W. Shi Motility and chemotaxis in tissue penetration of oral epithelial cell layers by Treponema denticola Infect. Immun. 2001 69 6276 6283 (Pubitemid 32885192)
33. K. A. Eaton D. R. Morgan S. Krakowka Motility as a factor in the colonisation of gnotobiotic piglets by Helicobacter pylori J. Med. Microbiol. 1992 37 123 127
34. S. Ganai R. B. Arenas J. P. Sauer B. Bentley N. S. Forbes In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis Cancer Gene Ther. 2011 18 457 466
35. N. S. Forbes L. L. Munn D. Fukumura R. K. Jain Sparse initial entrapment of systemically injected Salmonella typhimurium leads to heterogeneous accumulation within tumors Cancer Res. 2003 63 5188 5193 (Pubitemid 37139825)
36. J. L. Sherwood J. C. Sung R. M. Ford E. J. Fernandez J. E. Maneval J. A. Smith Analysis of bacterial random motility in a porous medium using magnetic resonance imaging and immunomagnetic labeling Environ. Sci. Technol. 2003 37 781 785 (Pubitemid 36236696)
37. M. S. Olson R. M. Ford J. A. Smith E. J. Fernandez Analysis of column tortuosity for MnCl2 and bacterial diffusion using magnetic resonance imaging Environ. Sci. Technol. 2005 39 149 154 (Pubitemid 40066287)
38. J. Stritzker S. Weibel C. Seubert A. Gotz A. Tresch N. van Rooijen T. A. Oelschlaeger P. J. Hill I. Gentschev A. A. Szalay Enterobacterial tumor colonization in mice depends on bacterial metabolism and macrophages but is independent of chemotaxis and motility Int. J. Med. Microbiol. 2010 300 449 456
39. K. Crull D. Bumann S. Weiss Influence of infection route and virulence factors on colonization of solid tumors by Salmonella enterica serovar Typhimurium FEMS Immunol. Med. Microbiol. 2011 62 75 83
40. M. W. Becker D. W. Metge S. A. Collins A. M. Shapiro R. W. Harvey Bacterial transport experiments in fractured crystalline bedrock Ground Water 2003 41 682 692
41. J. Liu R. M. Ford J. A. Smith Idling time of motile bacteria contributes to retardation and dispersion in sand porous medium Environ. Sci. Technol. 2011 45 3945 3951
42. J. Mannik R. Driessen P. Galajda J. E. Keymer C. Dekker Bacterial growth and motility in sub-micron constrictions Proc. Natl. Acad. Sci. U. S. A. 2009 106 14861 14866
43. J. Theys O. Pennington L. Dubois G. Anlezark T. Vaughan A. Mengesha W. Landuyt J. Anne P. J. Burke P. Durre B. G. Wouters N. P. Minton P. Lambin Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo Br. J. Cancer 2006 95 1212 1219 (Pubitemid 44658485)
44. S. N. Jiang T. X. Phan T. K. Nam V. H. Nguyen H. S. Kim H. S. Bom H. E. Choy Y. Hong J. J. Min Inhibition of tumor growth and metastasis by a combination of Escherichia coli-mediated cytolytic therapy and radiotherapy Mol. Ther. 2010 18 635 642
45. M. Loeffler G. Le'Negrate M. Krajewska J. C. Reed Attenuated Salmonella engineered to produce human cytokine LIGHT inhibit tumor growth Proc. Natl. Acad. Sci. U. S. A. 2007 104 12879 12883 (Pubitemid 47255248)
46. I. Gentschev J. Fensterle A. Schmidt T. Potapenko J. Troppmair W. Goebel U. R. Rapp Use of a recombinant Salmonella enterica serovar Typhimurium strain expressing C-Raf for protection against C-Raf induced lung adenoma in mice BMC Cancer 2005 5 15
47. M. Sznol S. L. Lin D. Bermudes L. M. Zheng I. King Use of preferentially replicating bacteria for the treatment of cancer J. Clin. Invest. 2000 105 1027 1030 (Pubitemid 30217683)
48. F. Avogadri C. Martinoli L. Petrovska C. Chiodoni P. Transidico V. Bronte R. Longhi M. P. Colombo G. Dougan M. Rescigno Cancer immunotherapy based on killing of Salmonella-infected tumor cells Cancer Res. 2005 65 3920 3927 (Pubitemid 40616374)
49. S. Ganai R. B. Arenas J. P. Sauer B. Bentley N. S. Forbes In tumors Salmonella migrate away from vasculature toward the transition zone and induce apoptosis Cancer Gene Ther. 2011 18 457 466
50. C. L. Walsh B. M. Babin R. W. Kasinskas J. A. Foster M. J. McGarry N. S. Forbes A multipurpose microfluidic device designed to mimic microenvironment gradients and develop targeted cancer therapeutics Lab Chip 2009 9 545 554
51. C. Clairmont K. C. Lee J. Pike M. Ittensohn K. B. Low J. Pawelek D. Bermudes S. M. Brecher D. Margitich J. Turnier Z. Li X. Luo I. King L. M. Zheng Biodistribution and genetic stability of the novel antitumor agent VNP20009, a genetically modified strain of Salmonella typhimurium J. Infect. Dis. 2000 181 1996 2002 (Pubitemid 30416163)