An ORF1-rearranged hepatitis e virus derived from a chronically infected patient efficiently replicates in cell culture

Journal of Viral Hepatitis

Volumn 21, Issue 6, 2014, Pages 447-456

  Johne, R ^a   Reetz, J ^a   Ulrich, R G ^b   Machnowska, P ^a   Sachsenroder J ^a   Nickel, P ^c   Hofmann, J ^c  

^a FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^b FEDERAL RESEARCH INSTITUTE FOR ANIMAL HEALTH   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

cell culture; cell line; genome insertion; hepatitis E virus

Indexed keywords

IMMUNOSUPPRESSIVE AGENT; NUCLEOTIDE; RIBOSOME PROTEIN; VIRUS RNA;

ADULT; ARTICLE; BLOOD SAMPLING; CARCINOMA CELL; CASE REPORT; CELL CULTURE; DENSITY GRADIENT CENTRIFUGATION; GENE EXPRESSION; GENE REARRANGEMENT; GENOTYPE; HEPATITIS E; HEPATITIS E VIRUS; HUMAN; HUMAN CELL; IMMUNOELECTRON MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY TRANSPLANTATION; LUNG CARCINOMA; MALE; MIDDLE AGED; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; POINT MUTATION; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SERUM; SURGICAL PATIENT; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL INOCULATION; VIRUS GENOME; VIRUS ISOLATION; VIRUS REPLICATION; VIRUS STRAIN; WILD BOAR; CHRONIC DISEASE; DNA SEQUENCE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; ISOLATION AND PURIFICATION; MOLECULAR GENETICS; PHYSIOLOGY; REAL TIME POLYMERASE CHAIN REACTION; TUMOR CELL LINE; VIROLOGY; VIRUS CULTURE;

CELL LINE, TUMOR; CENTRIFUGATION, DENSITY GRADIENT; CHRONIC DISEASE; GENE REARRANGEMENT; HEPATITIS E; HEPATITIS E VIRUS; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; OPEN READING FRAMES; POINT MUTATION; REAL-TIME POLYMERASE CHAIN REACTION; RNA, VIRAL; SEQUENCE ANALYSIS, DNA; VIRUS CULTIVATION; VIRUS REPLICATION;

EID: 84901057756     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12157     Document Type: Article

References (38)

1. Aggarwal R, Jameel S,. Hepatitis E vaccine. Hepatol Int 2008; 2: 308-315.
2. Mushahwar IK,. Hepatitis E virus: molecular virology, clinical features, diagnosis, transmission, epidemiology, and prevention. J Med Virol 2008; 80: 646-658. (Pubitemid 351358563)
3. Aggarwal R, Jameel S,. Hepatitis E. Hepatology 2011; 54: 2218-2226.
4. Meng XJ,. From barnyard to food table: the omnipresence of hepatitis E virus and risk for zoonotic infection and food safety. Virus Res 2011; 161: 23-30.
5. Colson P, Borentain P, Queyriaux B, et al,. Pig liver sausage as a source of hepatitis E virus transmission to humans. J Infect Dis 2010; 202: 825-834.
6. Matsuda H, Okada K, Takahashi K, Mishiro S,. Severe hepatitis E virus infection after ingestion of uncooked liver from a wild boar. J Infect Dis 2003; 188: 944. (Pubitemid 37176043)
7. Tei S, Kitajima N, Takahashi K, et al,. Zoonotic transmission of hepatitis E virus from deer to human beings. Lancet 2003; 362: 371-373. (Pubitemid 36945060)
8. Pavio N, Meng XJ, Renou C,. Zoonotic hepatitis E: animal reservoirs and emerging risks. Vet Res 2010; 41: 46.
9. Kumar A, Beniwal M, Kar P, et al,. Hepatitis E in pregnancy. Int J Gynaecol Obstet 2004; 85: 240-244. (Pubitemid 38622553)
10. Gerolami R, Moal V, Colson P,. Chronic hepatitis E with cirrhosis in a kidney-transplant recipient. N Engl J Med 2008; 358: 859-860. (Pubitemid 351281667)
11. Kamar N, Selves J, Mansuy JM, et al,. Hepatitis E virus and chronic hepatitis in organ-transplant recipients. N Engl J Med 2008; 358: 811-817. (Pubitemid 351281642)
12. Schlosser B, Stein A, Neuhaus R, et al,. Liver transplant from a donor with occult HEV infection induced chronic hepatitis and cirrhosis in the recipient. J Hepatol 2012; 56: 500-502.
13. le Coutre P, Meisel H, Hofmann J, et al,. Reactivation of hepatitis E infection in a patient with acute lymphoblastic leukaemia after allogeneic stem cell transplantation. Gut 2009; 58: 699-702.
14. Meng XJ, Anderson DA, Arankalle VA, et al,. Family Hepeviridae. In:, King AMQ, Adams MJ, Carstens EB, Lefkowitz EJ, eds. Virus Taxonomy, Ninth Report of the ICTV. London, Waltham, San Diego: Academic Press, 2012: 1021-1028.
15. Sehgal D, Thomas S, Chakraborty M, et al,. Expression and processing of the Hepatitis E virus ORF1 nonstructural polyprotein. Virol J 2006; 3: 38.
16. Purdy MA,. Evolution of the hepatitis E virus polyproline region: order from disorder. J Virol 2012; 86: 10186-10193.
17. Smith DB, Vanek J, Ramalingam S, et al,. Evolution of the hepatitis E virus hypervariable region. J Gen Virol 2012; 93: 2408-2418.
18. Meng XJ,. Hepatitis E virus: animal reservoirs and zoonotic risk. Vet Microbiol 2010; 140: 256-265.
19. Tanaka T, Takahashi M, Kusano E, et al,. Development and evaluation of an efficient cell-culture system for Hepatitis E virus. J Gen Virol 2007; 88: 903-911. (Pubitemid 46359560)
20. Takahashi M, Tanaka T, Takahashi H, et al,. Hepatitis E Virus (HEV) strains in serum samples can replicate efficiently in cultured cells despite the coexistence of HEV antibodies: characterization of HEV virions in blood circulation. J Clin Microbiol 2010; 48: 1112-1125.
21. Zhang HY, Chen DS, Wu YQ, et al,. Both swine and human cells are capable to support the replication of swine hepatitis E virus type 4 in vitro. Virus Res 2011; 158: 289-293.
22. Schielke A, Filter M, Appel B, et al,. Thermal stability of hepatitis E virus assessed by a molecular biological approach. Virol J 2011; 8: 487.
23. Berto A, Van der Poel WHM, Hakze-van der Honing R, et al,. Replication of hepatitis E virus in three-dimensional cell culture. J Virol Methods 2013; 187: 327-332.
24. Rogee S, Talbot N, Caperna T, et al,. New models of hepatitis E virus replication in human and porcine hepatocyte cell lines. J Gen Virol 2013; 94: 549-558.
25. Shukla P, Nguyen HT, Torian U, et al,. Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant. Proc Natl Acad Sci USA 2011; 108: 2438-2443.
26. Nguyen HT, Torian U, Faulk K, et al,. A naturally occurring human/hepatitis E recombinant virus predominates in serum but not in faeces of a chronic hepatitis E patient and has a growth advantage in cell culture. J Gen Virol 2012; 93: 526-530.
27. Shukla P, Nguyen HT, Faulk K, et al,. Adaptation of a genotype 3 hepatitis E virus to efficient growth in cell culture depends on an inserted human gene segment acquired by recombination. J Virol 2012; 86: 5697-5707.
28. Schielke A, Sachs K, Lierz M, et al,. Detection of hepatitis E virus in wild boars of rural and urban regions in Germany and whole genome characterization of an endemic strain. Virol J 2009; 6: 58.
29. Jothikumar N, Cromeans TL, Robertson BH, et al,. A broadly reactive one-step real-time RT-PCR assay for rapid and sensitive detection of hepatitis E virus. J Virol Methods 2006; 131: 65-71. (Pubitemid 41772562)
30. Bourne JA,. Handbook of Immunoperoxidase Staining Methods. Immuno- chemistry laboratory. Santa Barbara, CA: Dako Corporation 1983: 7-37.
31. Berto A, Grierson S, Hakze-van der Honing R, et al,. Viable hepatitis E virus in pork liver sausage, France. Emerg Infect Dis 2013; 19: 264-266.
32. Yamada K, Takahashi M, Hoshino Y, et al,. ORF3 protein of hepatitis E virus is essential for virion release from infected cells. J Gen Virol 2009; 90: 1880-1891.
33. Emerson SU, Arankalle VA, Purcell RH,. Thermal stability of hepatitis E virus. J Infect Dis 2005; 192: 930-933. (Pubitemid 41193092)
34. Barnaud E, Rogée S, Garry P, et al,. Thermal inactivation of infectious hepatitis E virus in experimentally contaminated food. Appl Environ Microbiol 2012; 78: 5153-5159.
35. Takahashi H, Tanaka T, Jirintai S, et al,. A549 and PLC/PRF/5 cells can support the efficient propagation of swine and wild boar hepatitis E virus (HEV) strains: demonstration of HEV infectivity of porcine liver sold as food. Arch Virol 2012; 157: 235-246.
36. Steinhauer DA,. Role of hemagglutinin cleavage for the pathogenicity of influenza virus. Virology 1999; 258: 1-20. (Pubitemid 29391776)
37. Kaverin NV, Ohuchi M, Ohuchi R, et al,. Phenotypic mixing with recombinant haemagglutinin of high cleavability mediates multi-cycle replication of human influenza virus in cell culture. J Gen Virol 1996; 77: 119-122. (Pubitemid 26031660)
38. Becher P, Tautz N,. RNA recombination in pestiviruses: cellular RNA sequences in viral genomes highlight the role of host factors for viral persistence and lethal disease. RNA Biol 2011; 8: 216-224.