Burst suppression-MAC and burst suppression-CP50 as measures of cerebral effects of anaesthetics

British Journal of Anaesthesia

Volumn 112, Issue 6, 2014, Pages 1067-1074

  Pilge, S ^a   Jordan, D ^b   Kreuzer, M ^b   Kochs, E F ^b   Schneider, G ^a  

^a UNIVERSITY OF WITTEN HERDECKE   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

anaesthetics; electroencephalography; inhalation; intravenous

Indexed keywords

ISOFLURANE; PROPOFOL; SEVOFLURANE;

ADULT; ANALYTICAL PARAMETERS; ARTERIAL PRESSURE; ARTICLE; BODY HEIGHT; BODY WEIGHT; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; ELECTROENCEPHALOGRAM; END TIDAL CARBON DIOXIDE TENSION; FEMALE; HEART RATE; HUMAN; MALE; MINIMUM ALVEOLAR CONCENTRATION; MINIMUM PLASMA CONCENTRATION; OXYGEN SATURATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

ANAESTHETICS, INHALATION; ANAESTHETICS, INTRAVENOUS; ELECTROENCEPHALOGRAPHY;

ADULT; ANESTHETICS, INHALATION; ANESTHETICS, INTRAVENOUS; BRAIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; ISOFLURANE; MALE; METHYL ETHERS; PROPOFOL;

EID: 84901045057     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aeu016     Document Type: Article

References (56)

1. Eger EI II, Saidman LJ, Brandstater B. Minimum alveolar anesthetic concentration: A standard of anesthetic potency. Anesthesiology 1965; 26: 756-63
2. Smith C, McEwan AI, Jhaveri R, et al. The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision. Anesthesiology 1994; 81: 820-8 (Pubitemid 24332614)
3. Campagna JA, Miller KW, Forman SA. Mechanisms of actions of inhaled anesthetics. N Engl J Med 2003; 348: 2110-24 (Pubitemid 36583307)
4. Sonner JM, Antognini JF, Dutton RC, et al. Inhaled anesthetics and immobility: Mechanisms, mysteries, and minimum alveolar anesthetic concentration. Anesth Analg 2003; 97: 718-40 (Pubitemid 37046437)
5. Antognini JF,SchwartzK.Exaggeratedanestheticrequirementsinthe preferentially anesthetized brain. Anesthesiology 1993; 79: 1244-9
6. Rampil IJ,MasonP, SinghH.Anestheticpotency(MAC) is independent of forebrain structures in the rat. Anesthesiology 1993; 78: 707-12 (Pubitemid 23110045)
7. Grasshoff C, Antkowiak B. Propofol and sevoflurane depress spinal neurons in vitro via different molecular targets. Anesthesiology 2004; 101: 1167-76 (Pubitemid 39430797)
8. Alkire MT, Haier RJ, Fallon JH. Toward a unified theory of narcosis: Brain imaging evidence for a thalamocortical switch as the neurophysiologic basis of anesthetic-induced unconsciousness. Conscious Cogn 2000; 9: 370-86
9. Veselis RA, Reinsel RA. Electroencephalographic effects of sedative hypnotics. Anesthesiology 1992; 77: 837-8
10. Feshchenko VA, Veselis RA, Reinsel RA. Comparison of the EEG effects of midazolam, thiopental, and propofol: The role of underlying oscillatory systems. Neuropsychobiology 1997; 35: 211-20 (Pubitemid 27212161)
11. Feshchenko VA, Veselis RA, Reinsel RA. Propofol-induced alpha rhythm. Neuropsychobiology 2004; 50: 257-66 (Pubitemid 39279421)
12. Veselis RA, Feshchenko VA, Reinsel RA, Dnistrian AM, Beattie B, Akhurst TJ. Thiopental and propofol affect different regions of the brain at similar pharmacologic effects. Anesth Analg 2004; 99: 399-408 (Pubitemid 38970409)
13. Dixon WJ. The up-and-down method for small samples. Am Stat Assoc J 1965; 60: 966-78
14. Korkmaz S,Wahlstrom G. The EEG burst suppression threshold test for the determination of CNS sensitivity to intravenous anesthetics in rats. Brain Res 1997; 1: 378-84
15. Fisher DM, Zwass MS. MAC of desflurane in 60% nitrous oxide in infants and children. Anesthesiology 1992; 76: 354-6
16. Johansen JW, Schneider G, Windsor AM, Sebel PS. Esmolol potentiates reduction of minimum alveolar isoflurane concentration by alfentanil. Anesth and Analg 1998; 87: 671-6 (Pubitemid 28397496)
17. Lerman J, Sikich N, Kleinman S, Yentis S. The pharmacology of sevoflurane in infants and children. Anesthesiology 1994; 80: 814-24 (Pubitemid 24128945)
18. Rampil IJ, Lockhart SH, Zwass MS, et al. Clinical characteristics of desflurane in surgical patients: Minimum alveolar concentration. Anesthesiology 1991; 74: 429-33
19. Quasha AL, Eger EI II, Tinker JH. Determination and applications of MAC. Anesthesiology 1980; 53: 315-34 (Pubitemid 10006760)
20. SchellerMS, Saidman LJ, Partridge BL.MACof sevoflurane in humans and the New Zealand white rabbit. Can J Anaesth 1988; 35: 153-6 (Pubitemid 18086002)
21. Stevens WD, Dolan WM, Gibbons RT, et al. Minimum alveolar concentrations (MAC) of isoflurande with and without nitrous oxide in patients of various ages. Anesthesiology 1975; 42: 197-200
22. Paul M, Fisher DM. Are estimates of MAC reliable? Anesthesiology 2001; 95: 1362-70 (Pubitemid 33126747)
23. Bolander HG,WahlstromG, Norberg L. Reevaluation of potencyand pharmacokinetic properties of somelipid-soluble barbiturates with an EEG-threshold method. Acta Pharmacol Toxicol 1984; 54: 33-40 (Pubitemid 14215968)
24. Ching S, Purdon PL, Vijayan S, Kopell NJ, Brown EN. A neurophysiological-metabolic model for burst suppression. Proc Natl Acad Sci USA 2012; 109: 3095-100
25. Young GB. The EEG in coma. J Clin Neurophysiol 2000; 17: 473-85
26. Vijn PC, SneydJR. I.V. anaesthesiaandEEG burst suppression in rats: Bolus injections and closed-loop infusions. Br J Anaesth 1998; 81: 415-21 (Pubitemid 28416626)
27. Alkire MT, Hudetz AG, Tononi G. Consciousness and anesthesia. Science 2008; 322: 876-80
28. Milde LN, Milde JH, Michenfelder JD. Cerebral functional, metabolic, and hemodynamic effects of etomidate in dogs. Anesthesiology 1985; 63: 371-7 (Pubitemid 16236052)
29. Hudetz AG. General anesthesia and human brain connectivity. Brain Connect 2012; 2: 291-302
30. Cavazzuti M, Porro CA, Biral GP, Benassi C, Barbieri GC. Ketamine effects on local cerebral blood flow and metabolism in the rat. J Cereb Blood Flow Metab 1987; 7: 806-11 (Pubitemid 18029825)
31. Bonhomme V, Boveroux P, Hans P, et al. Influence of anesthesia on cerebral blood flow, cerebral metabolic rate, and brain functional connectivity. Curr Opin Anaesthesiol 2011; 24: 474-9
32. Boveroux P, Vanhaudenhuyse A, Bruno MA, et al. Breakdown of within-and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness. Anesthesiology 2010; 113: 1038-53
33. Breshears JD, Roland JL, Sharma M, et al. Stable and dynamic cortical electrophysiology of induction and emergence with propofol anesthesia. Proc Natl Acad Sci USA 2010; 107: 21170-5
34. Liu X, Lauer KK, Ward BD, Li SJ, Hudetz AG. Differential effects of deep sedation with propofol on the specific and nonspecific thalamocortical systems: A functional magnetic resonance imaging study. Anesthesiology 2013; 118: 59-69
35. Mashour GA, Alkire MT. Consciousness, anesthesia, and the thalamocortical system. Anesthesiology 2013; 118: 13-5
36. Schroter MS, Spoormaker VI, Schorer A, et al. Spatiotemporal reconfiguration of large-scale brain functional networks during propofolinduced loss of consciousness. J Neurosci 2012; 32: 12832-40
37. Akrawi WP, Drummond JC, Kalkman CJ, Patel PM. A comparison of the electrophysiologic characteristics of EEG burst-suppression as produced by isoflurane, thiopental, etomidate, and propofol. J Neurosurg Anesthesiol 1996; 8: 40-6
38. Hoffman WE, Edelman G. Comparison of isoflurane and desflurane anesthetic depth using burst suppression of the electroencephalogram in neurosurgical patients. Anesth Analg 1995; 81: 811-6
39. Maekawa T, Tommasino C, Shapiro HM, Keifer-Goodman J, KohlenbergerRW. Local cerebral blood flow and glucose utilization during isoflurane anesthesia in the rat. Anesthesiology 1986; 65: 144-51 (Pubitemid 16076038)
40. Cavazzuti M, Porro CA, Barbieri A, Galetti A. Brain and spinal cord metabolic activity during propofol anaesthesia. Br J Anaesth 1991; 66: 490-5
41. Michenfelder JD, Messick JM Jr, Theye RA. Simultaneous cerebral blood flow measured by direct and indirect methods. J Surg Res 1968; 8: 475-81
42. Kortelainen J, Koskinen M, Mustola S, Seppanen T. EEG frequency progression during induction of anesthesia: From start of infusion to onset of burst suppression pattern. Ann Int Conf IEEE Eng Med Biol Soc 2007: 1570-3
43. Kortelainen J, Koskinen M, Mustola S, Seppanen T. EEG spectral changes and onset of burst suppression pattern in propofol/remifentanil anesthesia. Ann Int Conf IEEE Eng Med Biol Soc 2008: 4980-3
44. Scott JC, Cooke JE, Stanski DR. Electroencephalographic quantitation of opioid effect: Comparative pharmacodynamics of fentanyl and sufentanil. Anesthesiology 1991; 74: 34-42
45. Kuizenga K, Wierda JM, Kalkman CJ. Biphasic EEG changes in relation to loss of consciousness during induction with thiopental, propofol, etomidate, midazolam or sevoflurane. Br J Anaesth 2001; 86: 354-60 (Pubitemid 32219947)
46. Hodgson PS, Liu SS. Epidural lidocaine decreases sevoflurane requirement for adequate depth of anesthesia as measured by the Bispectral Index monitor. Anesthesiology 2001;94: 799-803 (Pubitemid 32429750)
47. Matsuura T, Oda Y, Tanaka K, Mori T, Nishikawa K, Asada A. Advance of age decreases the minimum alveolar concentrations of isoflurane and sevoflurane for maintaining bispectral index below 50. Br J Anaesth 2009; 102: 331-5
48. Tsuruta S, Satsumae T, Mizutani T, et al. Minimum alveolar concentrations of sevoflurane for maintaining bispectral index below 50 in children. Paediatr Anaesth 2011; 21: 1124-7
49. Glass PS, Glen JB,Kenny GN, Schuttler J, Shafer SL.Nomenclature for computer-assisted infusion devices. Anesthesiology 1997; 86: 1430-1
50. Glass PS, Doherty M, Jacobs JR, Goodman D, Smith LR. Plasma concentration of fentanyl, with 70% nitrous oxide, to prevent movement at skin incision. Anesthesiology 1993; 78: 842-7; discussion 23A (Pubitemid 23141357)
51. Russell I. In: Jones J, ed. Clinical Anaesthesiology. London: Bailliere Tindall, 1989; 511-32
52. Albertin A, Dedola E, Bergonzi PC, Lombardo F, Fusco T, Torri G. The effect of adding two target-controlled concentrations (1-3 ng mL21) of remifentanil on MAC BAR of desflurane. Eur J Anaesthesiol 2006; 23: 510-6
53. Liu Z,Wang JF, Meng Y, et al. Effects of three target-controlled concentrations of sufentanil onMAC(BAR) of sevoflurane. CNS Neurosci Ther 2012; 18: 361-4
54. Davidson AJ, Wong A, Knottenbelt G, Sheppard S, Donath S, Frawley G. MAC-awake of sevoflurane in children. Paediatr Anaesth 2008; 18: 702-7 (Pubitemid 352000583)
55. Goto T, Nakata Y, Ishiguro Y, Niimi Y, Suwa K, Morita S. Minimum alveolar concentration-awake of Xenon alone and in combination with isoflurane or sevoflurane. Anesthesiology 2000; 93: 1188-93
56. Kihara S, Inomata S, Yaguchi Y, Toyooka H, Baba Y, Kohda Y. The awakening concentration of sevoflurane in children. Anesth Analg 2000; 91: 305-8 (Pubitemid 30624287)