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Volumn 4 APR, Issue , 2014, Pages

Antibody therapy for pediatric leukemia

Author keywords

Acute lymphoblastic leukemia; Acute myeloid leukemia; Antibodies; Bispecific antibodies; Childhood leukemia; Conjugated antibodies; Monoclonal

Indexed keywords

ALEMTUZUMAB; ANTINEOPLASTIC AGENT; ASPARAGINASE; AVE 9633; BLINATUMOMAB; CALICHEAMICIN; CYCLOPHOSPHAMIDE; CYTARABINE; DAUNORUBICIN; DCDT 2980S; DEXAMETHASONE; DOXORUBICIN; EPRATUZUMAB; FIRTECAN; GEMTUZUMAB; GEMTUZUMAB OZOGAMICIN; INOTUZUMAB OZOGAMICIN; MONOCLONAL ANTIBODY; OCRELIZUMAB; OFATUMUMAB; OZOGAMICIN; PREDNISONE; RITUXIMAB; SAR 3419; SGN CD19A; SGN CD33A; UNCLASSIFIED DRUG; UNINDEXED DRUG; VEDOTIN; VELTUZUMAB; VINCRISTINE;

EID: 84901044425     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2014.00082     Document Type: Review
Times cited : (16)

References (79)
  • 1
    • 33644798329 scopus 로고    scopus 로고
    • Childhood acute lymphoblastic leukaemia and relapse
    • doi: 10.1111/j.1365-2141.2005.05773.x
    • Gaynon PS. Childhood acute lymphoblastic leukaemia and relapse. Br J Haematol (2005) 131:579-87. doi: 10.1111/j.1365-2141.2005.05773.x.
    • (2005) Br J Haematol , vol.131 , pp. 579-587
    • Gaynon, P.S.1
  • 3
    • 84859401730 scopus 로고    scopus 로고
    • Late effects of acute lymphoblastic leukemia therapy in patients diagnosed at 0-20 years of age
    • doi:10.1182/asheducation-2011.1.238
    • Robison LL. Late effects of acute lymphoblastic leukemia therapy in patients diagnosed at 0-20 years of age. Hematology Am Soc Hematol Educ Program (2011) 2011:238-42. doi:10.1182/asheducation-2011.1.238.
    • (2011) Hematology Am Soc Hematol Educ Program , vol.2011 , pp. 238-242
    • Robison, L.L.1
  • 4
    • 23744511263 scopus 로고    scopus 로고
    • Safety and efficacy of gemtuzumab ozogamicin in pediatric patients with advanced CD33+ acute myeloid leukemia
    • doi:10.1182/blood-2004-10-3821
    • Arceci RJ, Sande J, Lange B, Shannon K, Franklin J, Hutchinson R, et al. Safety and efficacy of gemtuzumab ozogamicin in pediatric patients with advanced CD33+ acute myeloid leukemia. Blood (2005) 106:1183-8. doi:10.1182/blood-2004-10-3821.
    • (2005) Blood , vol.106 , pp. 1183-1188
    • Arceci, R.J.1    Sande, J.2    Lange, B.3    Shannon, K.4    Franklin, J.5    Hutchinson, R.6
  • 6
    • 79952660539 scopus 로고    scopus 로고
    • Antibody-drug conjugates: using monoclonal antibodies for delivery of cytotoxic payloads to cancer cells
    • doi:10.4155/tde.10.98
    • Goldmacher VS, Kovtun YV. Antibody-drug conjugates: using monoclonal antibodies for delivery of cytotoxic payloads to cancer cells. Ther Deliv (2011) 2:397-416. doi:10.4155/tde.10.98.
    • (2011) Ther Deliv , vol.2 , pp. 397-416
    • Goldmacher, V.S.1    Kovtun, Y.V.2
  • 7
    • 3042844293 scopus 로고    scopus 로고
    • Cancer immunotherapy: a treatment for the masses
    • doi:10.1126/science.1100369
    • Blattman JN, Greenberg PD. Cancer immunotherapy: a treatment for the masses. Science (2004) 305:200-5. doi:10.1126/science.1100369.
    • (2004) Science , vol.305 , pp. 200-205
    • Blattman, J.N.1    Greenberg, P.D.2
  • 9
    • 78650286160 scopus 로고    scopus 로고
    • Investigational antibody-drug conjugates for hematological malignancies
    • doi:10.1517/13543784.2011.539557
    • Polson AG, Ho WY, Ramakrishnan V. Investigational antibody-drug conjugates for hematological malignancies. Expert Opin Investig Drugs (2011) 20:75-85. doi:10.1517/13543784.2011.539557.
    • (2011) Expert Opin Investig Drugs , vol.20 , pp. 75-85
    • Polson, A.G.1    Ho, W.Y.2    Ramakrishnan, V.3
  • 10
    • 0038347495 scopus 로고    scopus 로고
    • Renaissance of cancer therapeutic antibodies
    • doi:10.1016/S1359-6446(03)02714-4
    • Glennie MJ, van de Winkel JG. Renaissance of cancer therapeutic antibodies. Drug Discov Today (2003) 8:503-10. doi:10.1016/S1359-6446(03)02714-4.
    • (2003) Drug Discov Today , vol.8 , pp. 503-510
    • Glennie, M.J.1    van de Winkel, J.G.2
  • 11
    • 11244265898 scopus 로고    scopus 로고
    • Identification and validation of cell surface antigens for antibody targeting in oncology
    • doi:10.1677/erc.1.00766
    • Carter P, Smith L, Ryan M. Identification and validation of cell surface antigens for antibody targeting in oncology. Endocr Relat Cancer (2004) 11:659-87. doi:10.1677/erc.1.00766.
    • (2004) Endocr Relat Cancer , vol.11 , pp. 659-687
    • Carter, P.1    Smith, L.2    Ryan, M.3
  • 12
    • 49449119098 scopus 로고    scopus 로고
    • Antibody-drug conjugates for cancer therapy
    • doi:10.1097/PPO.0b013e318172d704
    • Carter PJ, Senter PD. Antibody-drug conjugates for cancer therapy. Cancer J (2008) 14:154-69. doi:10.1097/PPO.0b013e318172d704.
    • (2008) Cancer J , vol.14 , pp. 154-169
    • Carter, P.J.1    Senter, P.D.2
  • 13
    • 77955312203 scopus 로고    scopus 로고
    • Antibody-drug conjugates: targeted drug delivery for cancer
    • doi:10.1016/j.cbpa.2010.06.170
    • Alley SC, Okeley NM, Senter PD. Antibody-drug conjugates: targeted drug delivery for cancer. Curr Opin Chem Biol (2010) 14:529-37. doi:10.1016/j.cbpa.2010.06.170.
    • (2010) Curr Opin Chem Biol , vol.14 , pp. 529-537
    • Alley, S.C.1    Okeley, N.M.2    Senter, P.D.3
  • 14
    • 34247876138 scopus 로고    scopus 로고
    • Development trends for monoclonal antibody cancer therapeutics
    • doi:10.1038/nrd2241
    • Reichert JM, Valge-Archer VE. Development trends for monoclonal antibody cancer therapeutics. Nat Rev Drug Discov (2007) 6:349-56. doi:10.1038/nrd2241.
    • (2007) Nat Rev Drug Discov , vol.6 , pp. 349-356
    • Reichert, J.M.1    Valge-Archer, V.E.2
  • 15
    • 33644505446 scopus 로고    scopus 로고
    • Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates
    • doi:10.1158/0008-5472.can-05-2883
    • Law CL, Gordon KA, Toki BE, Yamane AK, Hering MA, Cerveny CG, et al. Lymphocyte activation antigen CD70 expressed by renal cell carcinoma is a potential therapeutic target for anti-CD70 antibody-drug conjugates. Cancer Res (2006) 66:2328-37. doi:10.1158/0008-5472.can-05-2883.
    • (2006) Cancer Res , vol.66 , pp. 2328-2337
    • Law, C.L.1    Gordon, K.A.2    Toki, B.E.3    Yamane, A.K.4    Hering, M.A.5    Cerveny, C.G.6
  • 16
    • 48049118634 scopus 로고    scopus 로고
    • Approved monoclonal antibodies for cancer therapy
    • doi:10.1517/14712598.8.8.1151
    • Boyiadzis M, Foon KA. Approved monoclonal antibodies for cancer therapy. Expert Opin Biol Ther (2008) 8:1151-8. doi:10.1517/14712598.8.8.1151.
    • (2008) Expert Opin Biol Ther , vol.8 , pp. 1151-1158
    • Boyiadzis, M.1    Foon, K.A.2
  • 17
    • 0037165261 scopus 로고    scopus 로고
    • CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma
    • doi:10.1056/NEJMoa011795
    • Coiffier B, Lepage E, Briere J, Herbrecht R, Tilly H, Bouabdallah R, et al. CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med (2002) 346:235-42. doi:10.1056/NEJMoa011795.
    • (2002) N Engl J Med , vol.346 , pp. 235-242
    • Coiffier, B.1    Lepage, E.2    Briere, J.3    Herbrecht, R.4    Tilly, H.5    Bouabdallah, R.6
  • 18
    • 33645830511 scopus 로고    scopus 로고
    • Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia
    • doi:10.1002/cncr.21776
    • Thomas DA, Faderl S, O'Brien S, Bueso-Ramos C, Cortes J, Garcia-Manero G, et al. Chemoimmunotherapy with hyper-CVAD plus rituximab for the treatment of adult Burkitt and Burkitt-type lymphoma or acute lymphoblastic leukemia. Cancer (2006) 106:1569-80. doi:10.1002/cncr.21776.
    • (2006) Cancer , vol.106 , pp. 1569-1580
    • Thomas, D.A.1    Faderl, S.2    O'Brien, S.3    Bueso-Ramos, C.4    Cortes, J.5    Garcia-Manero, G.6
  • 19
    • 77955504706 scopus 로고    scopus 로고
    • Phase II window study on rituximab in newly diagnosed pediatric mature B-cell non-Hodgkin's lymphoma and Burkitt leukemia
    • doi:10.1200/jco.2009.26.6791
    • Meinhardt A, Burkhardt B, Zimmermann M, Borkhardt A, Kontny U, Klingebiel T, et al. Phase II window study on rituximab in newly diagnosed pediatric mature B-cell non-Hodgkin's lymphoma and Burkitt leukemia. J Clin Oncol (2010) 28:3115-21. doi:10.1200/jco.2009.26.6791.
    • (2010) J Clin Oncol , vol.28 , pp. 3115-3121
    • Meinhardt, A.1    Burkhardt, B.2    Zimmermann, M.3    Borkhardt, A.4    Kontny, U.5    Klingebiel, T.6
  • 20
    • 84884585831 scopus 로고    scopus 로고
    • Treatment challenges in the management of relapsed or refractory non-Hodgkin's lymphoma-novel and emerging therapies
    • doi:10.2147/cmar.s34273
    • Chao MP. Treatment challenges in the management of relapsed or refractory non-Hodgkin's lymphoma-novel and emerging therapies. Cancer Manag Res (2013) 5:251-69. doi:10.2147/cmar.s34273.
    • (2013) Cancer Manag Res , vol.5 , pp. 251-269
    • Chao, M.P.1
  • 21
    • 84860006054 scopus 로고    scopus 로고
    • Chemoimmunotherapy with ofatumumab in combination with CHOP in previously untreated follicular lymphoma
    • doi:10.1111/j.1365-2141.2012.09086.x
    • Czuczman MS, Hess G, Gadeberg OV, Pedersen LM, Goldstein N, Gupta I, et al. Chemoimmunotherapy with ofatumumab in combination with CHOP in previously untreated follicular lymphoma. Br J Haematol (2012) 157:438-45. doi:10.1111/j.1365-2141.2012.09086.x.
    • (2012) Br J Haematol , vol.157 , pp. 438-445
    • Czuczman, M.S.1    Hess, G.2    Gadeberg, O.V.3    Pedersen, L.M.4    Goldstein, N.5    Gupta, I.6
  • 22
    • 71049160105 scopus 로고    scopus 로고
    • A phase II study of Campath-1H in children with relapsed or refractory acute lymphoblastic leukemia: a Children's Oncology Group report
    • doi:10.1002/pbc.22209
    • Angiolillo AL, Yu AL, Reaman G, Ingle AM, Secola R, Adamson PC. A phase II study of Campath-1H in children with relapsed or refractory acute lymphoblastic leukemia: a Children's Oncology Group report. Pediatr Blood Cancer (2009) 53:978-83. doi:10.1002/pbc.22209.
    • (2009) Pediatr Blood Cancer , vol.53 , pp. 978-983
    • Angiolillo, A.L.1    Yu, A.L.2    Reaman, G.3    Ingle, A.M.4    Secola, R.5    Adamson, P.C.6
  • 23
    • 24644476583 scopus 로고    scopus 로고
    • Combination antibody therapy with epratuzumab and rituximab in relapsed or refractory non-Hodgkin's lymphoma
    • doi:10.1200/jco.2005.13.821
    • Leonard JP, Coleman M, Ketas J, Ashe M, Fiore JM, Furman RR, et al. Combination antibody therapy with epratuzumab and rituximab in relapsed or refractory non-Hodgkin's lymphoma. J Clin Oncol (2005) 23:5044-51. doi:10.1200/jco.2005.13.821.
    • (2005) J Clin Oncol , vol.23 , pp. 5044-5051
    • Leonard, J.P.1    Coleman, M.2    Ketas, J.3    Ashe, M.4    Fiore, J.M.5    Furman, R.R.6
  • 24
    • 49249109608 scopus 로고    scopus 로고
    • Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study
    • doi:10.1200/jco.2007.15.3528
    • Raetz EA, Cairo MS, Borowitz MJ, Blaney SM, Krailo MD, Leil TA, et al. Chemoimmunotherapy reinduction with epratuzumab in children with acute lymphoblastic leukemia in marrow relapse: a Children's Oncology Group Pilot Study. J Clin Oncol (2008) 26:3756-62. doi:10.1200/jco.2007.15.3528.
    • (2008) J Clin Oncol , vol.26 , pp. 3756-3762
    • Raetz, E.A.1    Cairo, M.S.2    Borowitz, M.J.3    Blaney, S.M.4    Krailo, M.D.5    Leil, T.A.6
  • 25
    • 84901054214 scopus 로고    scopus 로고
    • Reinduction chemoimmunotherapy with epratuzumab in relapsed acute lymphoblastic leukemia (ALL) in children, adolescents and young adults: results from Children's Oncology Group (COG) study ADVL04P2
    • Raetz EA, Cairo MS, Borowitz MJ, Lu X, Devidas M, Reid JM, et al. Reinduction chemoimmunotherapy with epratuzumab in relapsed acute lymphoblastic leukemia (ALL) in children, adolescents and young adults: results from Children's Oncology Group (COG) study ADVL04P2. Blood (2013) 122(21):355.
    • (2013) Blood , vol.122 , Issue.21 , pp. 355
    • Raetz, E.A.1    Cairo, M.S.2    Borowitz, M.J.3    Lu, X.4    Devidas, M.5    Reid, J.M.6
  • 26
    • 67449158986 scopus 로고    scopus 로고
    • Superior antitumor activity of SAR3419 to rituximab in xenograft models for non-Hodgkin's lymphoma
    • doi:10.1158/1078-0432.ccr-08-2808
    • Al-Katib AM, Aboukameel A, Mohammad R, Bissery MC, Zuany-Amorim C. Superior antitumor activity of SAR3419 to rituximab in xenograft models for non-Hodgkin's lymphoma. Clin Cancer Res (2009) 15:4038-45. doi:10.1158/1078-0432.ccr-08-2808.
    • (2009) Clin Cancer Res , vol.15 , pp. 4038-4045
    • Al-Katib, A.M.1    Aboukameel, A.2    Mohammad, R.3    Bissery, M.C.4    Zuany-Amorim, C.5
  • 27
    • 80054098573 scopus 로고    scopus 로고
    • Antibody conjugate therapeutics: challenges and potential
    • doi:10.1158/1078-0432.ccr-11-1417
    • Teicher BA, Chari RV. Antibody conjugate therapeutics: challenges and potential. Clin Cancer Res (2011) 17:6389-97. doi:10.1158/1078-0432.ccr-11-1417.
    • (2011) Clin Cancer Res , vol.17 , pp. 6389-6397
    • Teicher, B.A.1    Chari, R.V.2
  • 28
    • 84873053339 scopus 로고    scopus 로고
    • Antibody-drug conjugates in cancer therapy
    • doi:10.1146/annurev-med-050311-201823
    • Sievers EL, Senter PD. Antibody-drug conjugates in cancer therapy. Annu Rev Med (2013) 64:15-29. doi:10.1146/annurev-med-050311-201823.
    • (2013) Annu Rev Med , vol.64 , pp. 15-29
    • Sievers, E.L.1    Senter, P.D.2
  • 30
    • 84855675343 scopus 로고    scopus 로고
    • Epratuzumab-SN-38: a new antibody-drug conjugate for the therapy of hematologic malignancies
    • doi:10.1158/1535-7163.mct-11-0632
    • Sharkey RM, Govindan SV, Cardillo TM, Goldenberg DM. Epratuzumab-SN-38: a new antibody-drug conjugate for the therapy of hematologic malignancies. Mol Cancer Ther (2012) 11:224-34. doi:10.1158/1535-7163.mct-11-0632.
    • (2012) Mol Cancer Ther , vol.11 , pp. 224-234
    • Sharkey, R.M.1    Govindan, S.V.2    Cardillo, T.M.3    Goldenberg, D.M.4
  • 31
    • 33644787435 scopus 로고    scopus 로고
    • Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen
    • doi:10.1158/0008-5472.can-05-3973
    • Kovtun YV, Audette CA, Ye Y, Xie H, Ruberti MF, Phinney SJ, et al. Antibody-drug conjugates designed to eradicate tumors with homogeneous and heterogeneous expression of the target antigen. Cancer Res (2006) 66:3214-21. doi:10.1158/0008-5472.can-05-3973.
    • (2006) Cancer Res , vol.66 , pp. 3214-3221
    • Kovtun, Y.V.1    Audette, C.A.2    Ye, Y.3    Xie, H.4    Ruberti, M.F.5    Phinney, S.J.6
  • 32
    • 84901027132 scopus 로고    scopus 로고
    • Antibody-drug conjugates: where the action is: ADCs-the New Frontier
    • Carlson B. Antibody-drug conjugates: where the action is: ADCs-the New Frontier. Biotechnol Healthc (2012) 9:28-31.
    • (2012) Biotechnol Healthc , vol.9 , pp. 28-31
    • Carlson, B.1
  • 33
    • 6044223544 scopus 로고    scopus 로고
    • Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate
    • doi:10.1158/1078-0432.ccr-04-0789
    • Hamblett KJ, Senter PD, Chace DF, Sun MM, Lenox J, Cerveny CG, et al. Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate. Clin Cancer Res (2004) 10:7063-70. doi:10.1158/1078-0432.ccr-04-0789.
    • (2004) Clin Cancer Res , vol.10 , pp. 7063-7070
    • Hamblett, K.J.1    Senter, P.D.2    Chace, D.F.3    Sun, M.M.4    Lenox, J.5    Cerveny, C.G.6
  • 34
    • 84878857691 scopus 로고    scopus 로고
    • Analytical and bioanalytical technologies for characterizing antibody-drug conjugates
    • doi:10.1016/j.cbpa.2013.03.022
    • Alley SC, Anderson KE. Analytical and bioanalytical technologies for characterizing antibody-drug conjugates. Curr Opin Chem Biol (2013) 17:406-11. doi:10.1016/j.cbpa.2013.03.022.
    • (2013) Curr Opin Chem Biol , vol.17 , pp. 406-411
    • Alley, S.C.1    Anderson, K.E.2
  • 35
    • 44249087421 scopus 로고    scopus 로고
    • Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute myeloid leukemia: a report from the Children's Oncology Group
    • doi:10.1200/jco.2007.13.0096
    • Aplenc R, Alonzo TA, Gerbing RB, Lange BJ, Hurwitz CA, Wells RJ, et al. Safety and efficacy of gemtuzumab ozogamicin in combination with chemotherapy for pediatric acute myeloid leukemia: a report from the Children's Oncology Group. J Clin Oncol (2008) 26:2390-3295. doi:10.1200/jco.2007.13.0096.
    • (2008) J Clin Oncol , vol.26 , pp. 2390-3295
    • Aplenc, R.1    Alonzo, T.A.2    Gerbing, R.B.3    Lange, B.J.4    Hurwitz, C.A.5    Wells, R.J.6
  • 36
    • 84881305790 scopus 로고    scopus 로고
    • A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia
    • doi:10.1182/blood-2013-01-466706
    • Petersdorf SH, Kopecky KJ, Slovak M, Willman C, Nevill T, Brandwein J, et al. A phase 3 study of gemtuzumab ozogamicin during induction and postconsolidation therapy in younger patients with acute myeloid leukemia. Blood (2013) 121:4854-60. doi:10.1182/blood-2013-01-466706.
    • (2013) Blood , vol.121 , pp. 4854-4860
    • Petersdorf, S.H.1    Kopecky, K.J.2    Slovak, M.3    Willman, C.4    Nevill, T.5    Brandwein, J.6
  • 37
    • 80054113954 scopus 로고    scopus 로고
    • Antibody-drug conjugates of calicheamicin derivative: gemtuzumab ozogamicin and inotuzumab ozogamicin
    • doi:10.1158/1078-0432.ccr-11-0486
    • Ricart AD. Antibody-drug conjugates of calicheamicin derivative: gemtuzumab ozogamicin and inotuzumab ozogamicin. Clin Cancer Res (2011) 17:6417-27. doi:10.1158/1078-0432.ccr-11-0486.
    • (2011) Clin Cancer Res , vol.17 , pp. 6417-6427
    • Ricart, A.D.1
  • 38
    • 84886825064 scopus 로고    scopus 로고
    • SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML
    • doi:10.1182/blood-2013-03-491506
    • Kung Sutherland MS, Walter RB, Jeffrey SC, Burke PJ, Yu C, Kostner H, et al. SGN-CD33A: a novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML. Blood (2013) 122:1455-63. doi:10.1182/blood-2013-03-491506.
    • (2013) Blood , vol.122 , pp. 1455-1463
    • Kung Sutherland, M.S.1    Walter, R.B.2    Jeffrey, S.C.3    Burke, P.J.4    Yu, C.5    Kostner, H.6
  • 39
    • 84864548693 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004
    • doi:10.1182/blood-2012-03-416701
    • Hasle H, Abrahamsson J, Forestier E, Ha SY, Heldrup J, Jahnukainen K, et al. Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004. Blood (2012) 120:978-84. doi:10.1182/blood-2012-03-416701.
    • (2012) Blood , vol.120 , pp. 978-984
    • Hasle, H.1    Abrahamsson, J.2    Forestier, E.3    Ha, S.Y.4    Heldrup, J.5    Jahnukainen, K.6
  • 40
    • 84901003824 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin (GO) in children with de novo acute myeloid leukemia (AML) improves event-free survival (EFS) by reducing relapse risk-results from the randomized phase III Children's Oncology Group (COG) trial, AAML0531
    • Aplenc R, Alonzo TA, Sung L, Meshinchi S, Gerbing RB, Raimondi SC, et al. Gemtuzumab ozogamicin (GO) in children with de novo acute myeloid leukemia (AML) improves event-free survival (EFS) by reducing relapse risk-results from the randomized phase III Children's Oncology Group (COG) trial, AAML0531. Blood (2013) 122:355.
    • (2013) Blood , vol.122 , pp. 355
    • Aplenc, R.1    Alonzo, T.A.2    Sung, L.3    Meshinchi, S.4    Gerbing, R.B.5    Raimondi, S.C.6
  • 41
    • 84901003824 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin (GO) in children with de novo acute myeloid leukemia (AML) improves event-free survival (EFS) by reducing relapse risk-results from the randomized phase III Children's Oncology Group (COG) trial, AAML0531
    • Gamis A, Aplenc R, Alonzo TA, Sung L, Meshinchi S, Gerbing RB, et al. Gemtuzumab ozogamicin (GO) in children with de novo acute myeloid leukemia (AML) improves event-free survival (EFS) by reducing relapse risk-results from the randomized phase III Children's Oncology Group (COG) trial, AAML0531. Blood (2013) 122:355.
    • (2013) Blood , vol.122 , pp. 355
    • Gamis, A.1    Aplenc, R.2    Alonzo, T.A.3    Sung, L.4    Meshinchi, S.5    Gerbing, R.B.6
  • 42
    • 84859911350 scopus 로고    scopus 로고
    • Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study
    • doi:10.1016/s0140-6736(12)60485-1
    • Castaigne S, Pautas C, Terre C, Raffoux E, Bordessoule D, Bastie JN, et al. Effect of gemtuzumab ozogamicin on survival of adult patients with de-novo acute myeloid leukaemia (ALFA-0701): a randomised, open-label, phase 3 study. Lancet (2012) 379:1508-16. doi:10.1016/s0140-6736(12)60485-1.
    • (2012) Lancet , vol.379 , pp. 1508-1516
    • Castaigne, S.1    Pautas, C.2    Terre, C.3    Raffoux, E.4    Bordessoule, D.5    Bastie, J.N.6
  • 43
    • 0242643597 scopus 로고    scopus 로고
    • Molecular remission induced by gemtuzumab ozogamicin associated with donor lymphocyte infusions in t(4;11) acute lymphoblastic leukemia relapsed after transplantation
    • doi:10.1038/sj.leu.2403134
    • Balduzzi A, Rossi V, Corral L, Bonanomi S, Longoni D, Rovelli A, et al. Molecular remission induced by gemtuzumab ozogamicin associated with donor lymphocyte infusions in t(4;11) acute lymphoblastic leukemia relapsed after transplantation. Leukemia (2003) 17:2247-8. doi:10.1038/sj.leu.2403134.
    • (2003) Leukemia , vol.17 , pp. 2247-2248
    • Balduzzi, A.1    Rossi, V.2    Corral, L.3    Bonanomi, S.4    Longoni, D.5    Rovelli, A.6
  • 44
    • 0042161827 scopus 로고    scopus 로고
    • Successful use of gemtuzumab ozogamicin in a child with relapsed CD33-positive acute lymphoblastic leukaemia
    • doi:10.1046/j.1365-2141.2003.04485.x
    • Cotter M, Rooney S, O'Marcaigh A, Smith OP. Successful use of gemtuzumab ozogamicin in a child with relapsed CD33-positive acute lymphoblastic leukaemia. Br J Haematol (2003) 122:687-8. doi:10.1046/j.1365-2141.2003.04485.x.
    • (2003) Br J Haematol , vol.122 , pp. 687-688
    • Cotter, M.1    Rooney, S.2    O'Marcaigh, A.3    Smith, O.P.4
  • 45
    • 0037326082 scopus 로고    scopus 로고
    • Gemtuzumab ozogamicin in pediatric CD33-positive acute lymphoblastic leukemia: first clinical experiences and relation with cellular sensitivity to single agent calicheamicin
    • doi:10.1038/sj.leu.2402749
    • Zwaan CM, Reinhardt D, Jurgens H, Huismans DR, Hahlen K, Smith OP, et al. Gemtuzumab ozogamicin in pediatric CD33-positive acute lymphoblastic leukemia: first clinical experiences and relation with cellular sensitivity to single agent calicheamicin. Leukemia (2003) 17:468-70. doi:10.1038/sj.leu.2402749.
    • (2003) Leukemia , vol.17 , pp. 468-470
    • Zwaan, C.M.1    Reinhardt, D.2    Jurgens, H.3    Huismans, D.R.4    Hahlen, K.5    Smith, O.P.6
  • 46
    • 39749165647 scopus 로고    scopus 로고
    • Treatment of CD33 positive refractory acute lymphoblastic leukemia with Mylotarg
    • doi:10.1080/10428190701882161
    • Cheung KC, Wong LG, Yeung YM. Treatment of CD33 positive refractory acute lymphoblastic leukemia with Mylotarg. Leuk Lymphoma (2008) 49:596-7. doi:10.1080/10428190701882161.
    • (2008) Leuk Lymphoma , vol.49 , pp. 596-597
    • Cheung, K.C.1    Wong, L.G.2    Yeung, Y.M.3
  • 47
    • 56649083639 scopus 로고    scopus 로고
    • Combination of chemotherapy and gemtuzumab ozogamicin in adult Philadelphia positive acute lymphoblastic leukemia patient harboring CD33 expression
    • doi:10.1007/s12185-008-0123-2
    • Chevallier P, Mahe B, Garand R, Talmant P, Harousseau JL, Delaunay J. Combination of chemotherapy and gemtuzumab ozogamicin in adult Philadelphia positive acute lymphoblastic leukemia patient harboring CD33 expression. Int J Hematol (2008) 88:209-11. doi:10.1007/s12185-008-0123-2.
    • (2008) Int J Hematol , vol.88 , pp. 209-211
    • Chevallier, P.1    Mahe, B.2    Garand, R.3    Talmant, P.4    Harousseau, J.L.5    Delaunay, J.6
  • 49
    • 77956437053 scopus 로고    scopus 로고
    • Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma
    • doi:10.1038/leu.2010.141
    • Polson AG, Williams M, Gray AM, Fuji RN, Poon KA, Mcbride J, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia (2010) 24:1566-73. doi:10.1038/leu.2010.141.
    • (2010) Leukemia , vol.24 , pp. 1566-1573
    • Polson, A.G.1    Williams, M.2    Gray, A.M.3    Fuji, R.N.4    Poon, K.A.5    Mcbride, J.6
  • 50
    • 77954839504 scopus 로고    scopus 로고
    • Phase I study of inotuzumab ozogamicin (CMC-544) in Japanese patients with follicular lymphoma pretreated with rituximab-based therapy
    • doi:10.1111/j.1349-7006.2010.01601.x
    • Ogura M, Tobinai K, Hatake K, Uchida T, Kasai M, Oyama T, et al. Phase I study of inotuzumab ozogamicin (CMC-544) in Japanese patients with follicular lymphoma pretreated with rituximab-based therapy. Cancer Sci (2010) 101:1840-5. doi:10.1111/j.1349-7006.2010.01601.x.
    • (2010) Cancer Sci , vol.101 , pp. 1840-1845
    • Ogura, M.1    Tobinai, K.2    Hatake, K.3    Uchida, T.4    Kasai, M.5    Oyama, T.6
  • 51
    • 77949679970 scopus 로고    scopus 로고
    • Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial
    • doi:10.1158/1078-0432.ccr-09-2980
    • Wayne AS, Kreitman RJ, Findley HW, Lew G, Delbrook C, Steinberg SM, et al. Anti-CD22 immunotoxin RFB4(dsFv)-PE38 (BL22) for CD22-positive hematologic malignancies of childhood: preclinical studies and phase I clinical trial. Clin Cancer Res (2010) 16:1894-903. doi:10.1158/1078-0432.ccr-09-2980.
    • (2010) Clin Cancer Res , vol.16 , pp. 1894-1903
    • Wayne, A.S.1    Kreitman, R.J.2    Findley, H.W.3    Lew, G.4    Delbrook, C.5    Steinberg, S.M.6
  • 52
    • 84861542159 scopus 로고    scopus 로고
    • Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia
    • doi:10.1200/jco.2011.38.1756
    • Kreitman RJ, Tallman MS, Robak T, Coutre S, Wilson WH, Stetler-Stevenson M, et al. Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia. J Clin Oncol (2012) 30:1822-8. doi:10.1200/jco.2011.38.1756.
    • (2012) J Clin Oncol , vol.30 , pp. 1822-1828
    • Kreitman, R.J.1    Tallman, M.S.2    Robak, T.3    Coutre, S.4    Wilson, W.H.5    Stetler-Stevenson, M.6
  • 53
    • 84862786326 scopus 로고    scopus 로고
    • Inotuzumab ozogamicin, an anti-CD22-calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: a phase 2 study
    • doi:10.1016/s1470-2045(11)70386-2
    • Kantarjian H, Thomas D, Jorgensen J, Jabbour E, Kebriaei P, Rytting M, et al. Inotuzumab ozogamicin, an anti-CD22-calecheamicin conjugate, for refractory and relapsed acute lymphocytic leukaemia: a phase 2 study. Lancet Oncol (2012) 13:403-11. doi:10.1016/s1470-2045(11)70386-2.
    • (2012) Lancet Oncol , vol.13 , pp. 403-411
    • Kantarjian, H.1    Thomas, D.2    Jorgensen, J.3    Jabbour, E.4    Kebriaei, P.5    Rytting, M.6
  • 54
    • 67650873888 scopus 로고    scopus 로고
    • Safety and clinical activity of the anti-CD22 immunoconjugate inotuzumab ozogamicin (CMC-544) in combination with rituximab in follicular lymphoma or diffuse large B-cell lymphoma: preliminary report of a phase 1/2 study
    • doi:10.1200/JCO.2012.42.7211
    • Fayad L, Patel H, Verhoef G, Smith MR, Johnson PWM, Czuczman MS, et al. Safety and clinical activity of the anti-CD22 immunoconjugate inotuzumab ozogamicin (CMC-544) in combination with rituximab in follicular lymphoma or diffuse large B-cell lymphoma: preliminary report of a phase 1/2 study. ASH Annual Meeting Abstracts (2008) 11:266-312. doi:10.1200/JCO.2012.42.7211.
    • (2008) ASH Annual Meeting Abstracts , vol.11 , pp. 266-312
    • Fayad, L.1    Patel, H.2    Verhoef, G.3    Smith, M.R.4    Johnson, P.W.M.5    Czuczman, M.S.6
  • 55
    • 35548931579 scopus 로고    scopus 로고
    • Therapeutic potential of CD22-specific antibody-targeted chemotherapy using inotuzumab ozogamicin (CMC-544) for the treatment of acute lymphoblastic leukemia
    • doi:10.1038/sj.leu.2404866
    • Dijoseph JF, Dougher MM, Armellino DC, Evans DY, Damle NK. Therapeutic potential of CD22-specific antibody-targeted chemotherapy using inotuzumab ozogamicin (CMC-544) for the treatment of acute lymphoblastic leukemia. Leukemia (2007) 21:2240-5. doi:10.1038/sj.leu.2404866.
    • (2007) Leukemia , vol.21 , pp. 2240-2245
    • Dijoseph, J.F.1    Dougher, M.M.2    Armellino, D.C.3    Evans, D.Y.4    Damle, N.K.5
  • 56
    • 84880072016 scopus 로고    scopus 로고
    • DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma
    • doi:10.1158/1535-7163.mct-12-1173
    • Li D, Poon KA, Yu SF, Dere R, Go M, Lau J, et al. DCDT2980S, an anti-CD22-monomethyl auristatin E antibody-drug conjugate, is a potential treatment for non-Hodgkin lymphoma. Mol Cancer Ther (2013) 12:1255-65. doi:10.1158/1535-7163.mct-12-1173.
    • (2013) Mol Cancer Ther , vol.12 , pp. 1255-1265
    • Li, D.1    Poon, K.A.2    Yu, S.F.3    Dere, R.4    Go, M.5    Lau, J.6
  • 57
    • 84883377128 scopus 로고    scopus 로고
    • Targeting CD19 in B-cell lymphoma: emerging role of SAR3419
    • doi:10.2147/cmar.s45957
    • Raufi A, Ebrahim AS, Al-Katib A. Targeting CD19 in B-cell lymphoma: emerging role of SAR3419. Cancer Manag Res (2013) 5:225-33. doi:10.2147/cmar.s45957.
    • (2013) Cancer Manag Res , vol.5 , pp. 225-233
    • Raufi, A.1    Ebrahim, A.S.2    Al-Katib, A.3
  • 58
    • 80054095609 scopus 로고    scopus 로고
    • SAR3419: an anti-CD19-maytansinoid immunoconjugate for the treatment of B-cell malignancies
    • doi:10.1158/1078-0432.ccr-11-0485
    • Blanc V, Bousseau A, Caron A, Carrez C, Lutz RJ, Lambert JM. SAR3419: an anti-CD19-maytansinoid immunoconjugate for the treatment of B-cell malignancies. Clin Cancer Res (2011) 17:6448-58. doi:10.1158/1078-0432.ccr-11-0485.
    • (2011) Clin Cancer Res , vol.17 , pp. 6448-6458
    • Blanc, V.1    Bousseau, A.2    Caron, A.3    Carrez, C.4    Lutz, R.J.5    Lambert, J.M.6
  • 59
    • 0030995678 scopus 로고    scopus 로고
    • Prognostic significance of fluorescence intensity of surface marker expression in childhood B-precursor acute lymphoblastic leukemia. A Pediatric Oncology Group Study
    • Borowitz MJ, Shuster J, Carroll AJ, Nash M, Look AT, Camitta B, et al. Prognostic significance of fluorescence intensity of surface marker expression in childhood B-precursor acute lymphoblastic leukemia. A Pediatric Oncology Group Study. Blood (1997) 89:3960-6.
    • (1997) Blood , vol.89 , pp. 3960-3966
    • Borowitz, M.J.1    Shuster, J.2    Carroll, A.J.3    Nash, M.4    Look, A.T.5    Camitta, B.6
  • 60
    • 84892172931 scopus 로고    scopus 로고
    • A dose-escalation study of SAR3419, an anti-CD19 antibody maytansinoid conjugate, administered by intravenous infusion once weekly in patients with relapsed/refractory B-cell non-Hodgkin lymphoma
    • doi:10.1158/1078-0432.ccr-13-0580
    • Ribrag V, Dupuis J, Tilly H, Morschhauser F, Laine F, Houot R, et al. A dose-escalation study of SAR3419, an anti-CD19 antibody maytansinoid conjugate, administered by intravenous infusion once weekly in patients with relapsed/refractory B-cell non-Hodgkin lymphoma. Clin Cancer Res (2014) 20:213-20. doi:10.1158/1078-0432.ccr-13-0580.
    • (2014) Clin Cancer Res , vol.20 , pp. 213-220
    • Ribrag, V.1    Dupuis, J.2    Tilly, H.3    Morschhauser, F.4    Laine, F.5    Houot, R.6
  • 61
    • 84864544136 scopus 로고    scopus 로고
    • Phase I multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma
    • doi:10.1200/jco.2011.39.4403
    • Younes A, Kim S, Romaguera J, Copeland A, Farial Sde C, Kwak LW, et al. Phase I multidose-escalation study of the anti-CD19 maytansinoid immunoconjugate SAR3419 administered by intravenous infusion every 3 weeks to patients with relapsed/refractory B-cell lymphoma. J Clin Oncol (2012) 30:2776-82. doi:10.1200/jco.2011.39.4403.
    • (2012) J Clin Oncol , vol.30 , pp. 2776-2782
    • Younes, A.1    Kim, S.2    Romaguera, J.3    Copeland, A.4    Farial Sde, C.5    Kwak, L.W.6
  • 62
    • 84877100125 scopus 로고    scopus 로고
    • The anti-CD19 antibody-drug conjugate SAR3419 prevents hematolymphoid relapse postinduction therapy in preclinical models of pediatric acute lymphoblastic leukemia
    • doi:10.1158/1078-0432.ccr-12-3613
    • Carol H, Szymanska B, Evans K, Boehm I, Houghton PJ, Smith MA, et al. The anti-CD19 antibody-drug conjugate SAR3419 prevents hematolymphoid relapse postinduction therapy in preclinical models of pediatric acute lymphoblastic leukemia. Clin Cancer Res (2013) 19:1795-805. doi:10.1158/1078-0432.ccr-12-3613.
    • (2013) Clin Cancer Res , vol.19 , pp. 1795-1805
    • Carol, H.1    Szymanska, B.2    Evans, K.3    Boehm, I.4    Houghton, P.J.5    Smith, M.A.6
  • 63
    • 84899094594 scopus 로고    scopus 로고
    • A first-in-human phase 1 study of the antibody-drug conjugate SGN-CD19A in relapsed or refractory B-lineage acute leukemia and highly aggressive lymphoma
    • doi:10.3109/10428194.2013.764422
    • Fathi AT, Shah BD, Deangelo DJ, Silverman LB, Cooper TM, Albertson TM, et al. A first-in-human phase 1 study of the antibody-drug conjugate SGN-CD19A in relapsed or refractory B-lineage acute leukemia and highly aggressive lymphoma. Blood (2013) 122:1437. doi:10.3109/10428194.2013.764422.
    • (2013) Blood , vol.122 , pp. 1437
    • Fathi, A.T.1    Shah, B.D.2    Deangelo, D.J.3    Silverman, L.B.4    Cooper, T.M.5    Albertson, T.M.6
  • 64
    • 80054118081 scopus 로고    scopus 로고
    • Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox
    • doi:10.1158/1078-0432.ccr-11-0487
    • Kreitman RJ, Pastan I. Antibody fusion proteins: anti-CD22 recombinant immunotoxin moxetumomab pasudotox. Clin Cancer Res (2011) 17:6398-405. doi:10.1158/1078-0432.ccr-11-0487.
    • (2011) Clin Cancer Res , vol.17 , pp. 6398-6405
    • Kreitman, R.J.1    Pastan, I.2
  • 65
    • 79952950663 scopus 로고    scopus 로고
    • Complete remissions in 3 of 12 patients with pediatric acute lymphoblastic leukemia (ALL) during phase I testing of the anti-CD22 immunotoxin moxetumomab pasudotox
    • Wayne A, Bhojwani D, Richards K, Stetler-Stevenson M, Silverman LB, Jeha S, et al. Complete remissions in 3 of 12 patients with pediatric acute lymphoblastic leukemia (ALL) during phase I testing of the anti-CD22 immunotoxin moxetumomab pasudotox. ASH Annu Meet Abstr (2010) 116:3246.
    • (2010) ASH Annu Meet Abstr , vol.116 , pp. 3246
    • Wayne, A.1    Bhojwani, D.2    Richards, K.3    Stetler-Stevenson, M.4    Silverman, L.B.5    Jeha, S.6
  • 66
    • 34248193253 scopus 로고    scopus 로고
    • Immune surveillance of tumors
    • doi:10.1172/jci31405
    • Swann JB, Smyth MJ. Immune surveillance of tumors. J Clin Invest (2007) 117:1137-46. doi:10.1172/jci31405.
    • (2007) J Clin Invest , vol.117 , pp. 1137-1146
    • Swann, J.B.1    Smyth, M.J.2
  • 67
    • 33846860644 scopus 로고    scopus 로고
    • CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma
    • doi:10.1158/1078-0432.ccr-06-1734
    • Wahlin BE, Sander B, Christensson B, Kimby E. CD8+ T-cell content in diagnostic lymph nodes measured by flow cytometry is a predictor of survival in follicular lymphoma. Clin Cancer Res (2007) 13:388-97. doi:10.1158/1078-0432.ccr-06-1734.
    • (2007) Clin Cancer Res , vol.13 , pp. 388-397
    • Wahlin, B.E.1    Sander, B.2    Christensson, B.3    Kimby, E.4
  • 68
    • 60249091474 scopus 로고    scopus 로고
    • Use of tumour-responsive T cells as cancer treatment
    • doi:10.1016/s0140-6736(09)60404-9
    • Disis ML, Bernhard H, Jaffee EM. Use of tumour-responsive T cells as cancer treatment. Lancet (2009) 373:673-83. doi:10.1016/s0140-6736(09)60404-9.
    • (2009) Lancet , vol.373 , pp. 673-683
    • Disis, M.L.1    Bernhard, H.2    Jaffee, E.M.3
  • 69
    • 79955662260 scopus 로고    scopus 로고
    • Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab
    • doi:10.1016/j.yexcr.2011.03.010
    • Nagorsen D, Baeuerle PA. Immunomodulatory therapy of cancer with T cell-engaging BiTE antibody blinatumomab. Exp Cell Res (2011) 317:1255-60. doi:10.1016/j.yexcr.2011.03.010.
    • (2011) Exp Cell Res , vol.317 , pp. 1255-1260
    • Nagorsen, D.1    Baeuerle, P.A.2
  • 70
    • 0343415665 scopus 로고    scopus 로고
    • A recombinant bispecific single-chain antibody, CD19 x CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes
    • Loffler A, Kufer P, Lutterbuse R, Zettl F, Daniel PT, Schwenkenbecher JM, et al. A recombinant bispecific single-chain antibody, CD19 x CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes. Blood (2000) 95:2098-103.
    • (2000) Blood , vol.95 , pp. 2098-2103
    • Loffler, A.1    Kufer, P.2    Lutterbuse, R.3    Zettl, F.4    Daniel, P.T.5    Schwenkenbecher, J.M.6
  • 71
    • 84871491706 scopus 로고    scopus 로고
    • Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL
    • doi:10.1182/blood-2012-07-441030
    • Topp MS, Gokbuget N, Zugmaier G, Degenhard E, Goebeler ME, Klinger M, et al. Long-term follow-up of hematologic relapse-free survival in a phase 2 study of blinatumomab in patients with MRD in B-lineage ALL. Blood (2012) 120:5185-7. doi:10.1182/blood-2012-07-441030.
    • (2012) Blood , vol.120 , pp. 5185-5187
    • Topp, M.S.1    Gokbuget, N.2    Zugmaier, G.3    Degenhard, E.4    Goebeler, M.E.5    Klinger, M.6
  • 72
    • 78651290248 scopus 로고    scopus 로고
    • Complete remission after blinatumomab-induced donor T-cell activation in three pediatric patients with post-transplant relapsed acute lymphoblastic leukemia
    • doi:10.1038/leu.2010.239
    • Handgretinger R, Zugmaier G, Henze G, Kreyenberg H, Lang P, Von Stackelberg A. Complete remission after blinatumomab-induced donor T-cell activation in three pediatric patients with post-transplant relapsed acute lymphoblastic leukemia. Leukemia (2011) 25:181-4. doi:10.1038/leu.2010.239.
    • (2011) Leukemia , vol.25 , pp. 181-184
    • Handgretinger, R.1    Zugmaier, G.2    Henze, G.3    Kreyenberg, H.4    Lang, P.5    Von Stackelberg, A.6
  • 73
    • 84900991744 scopus 로고    scopus 로고
    • A phase 1/2 study of blinatumomab in pediatric patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia
    • Zugmaier G, Handgretinger R, Locatelli F, Rizzari C, Trippett TM, Borkhardt A, et al. A phase 1/2 study of blinatumomab in pediatric patients with relapsed/refractory B-cell precursor acute lymphoblastic leukemia. Blood (2013) 122:70.
    • (2013) Blood , vol.122 , pp. 70
    • Zugmaier, G.1    Handgretinger, R.2    Locatelli, F.3    Rizzari, C.4    Trippett, T.M.5    Borkhardt, A.6
  • 74
    • 84896335556 scopus 로고    scopus 로고
    • Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia
    • doi:10.1126/scitranslmed.3008226
    • Davila ML, Riviere I, Wang X, Bartido S, Park J, Curran K, et al. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci Transl Med (2014) 6:224ra225. doi:10.1126/scitranslmed.3008226.
    • (2014) Sci Transl Med , vol.6
    • Davila, M.L.1    Riviere, I.2    Wang, X.3    Bartido, S.4    Park, J.5    Curran, K.6
  • 75
    • 84890784667 scopus 로고    scopus 로고
    • Advanced targeted, cell and gene-therapy approaches for pediatric hematological malignancies: results and future perspectives
    • doi:10.3389/fonc.2013.00106
    • Magnani CF, Tettamanti S, Maltese F, Turazzi N, Biondi A, Biagi E. Advanced targeted, cell and gene-therapy approaches for pediatric hematological malignancies: results and future perspectives. Front Oncol (2013) 3:106. doi:10.3389/fonc.2013.00106.
    • (2013) Front Oncol , vol.3 , pp. 106
    • Magnani, C.F.1    Tettamanti, S.2    Maltese, F.3    Turazzi, N.4    Biondi, A.5    Biagi, E.6
  • 76
    • 84876325876 scopus 로고    scopus 로고
    • Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
    • doi:10.1056/NEJMoa1215134
    • Grupp SA, Kalos M, Barrett D, Aplenc R, Porter DL, Rheingold SR, et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med (2013) 368:1509-18. doi:10.1056/NEJMoa1215134.
    • (2013) N Engl J Med , vol.368 , pp. 1509-1518
    • Grupp, S.A.1    Kalos, M.2    Barrett, D.3    Aplenc, R.4    Porter, D.L.5    Rheingold, S.R.6
  • 77
    • 3042539425 scopus 로고    scopus 로고
    • Intraventricular treatment of relapsed central nervous system lymphoma with the anti-CD20 antibody rituximab
    • Schulz H, Pels H, Schmidt-Wolf I, Zeelen U, Germing U, Engert A. Intraventricular treatment of relapsed central nervous system lymphoma with the anti-CD20 antibody rituximab. Haematologica (2004) 89:753-4.
    • (2004) Haematologica , vol.89 , pp. 753-754
    • Schulz, H.1    Pels, H.2    Schmidt-Wolf, I.3    Zeelen, U.4    Germing, U.5    Engert, A.6
  • 78
    • 58849091797 scopus 로고    scopus 로고
    • Effectiveness of intrathecal rituximab in patients with acute lymphoblastic leukaemia relapsed to the CNS and resistant to conventional therapy
    • doi:10.1111/j.1365-2141.2008.07497.x
    • Jaime-Perez JC, Rodriguez-Romo LN, Gonzalez-Llano O, Chapa-Rodriguez A, Gomez-Almaguer D. Effectiveness of intrathecal rituximab in patients with acute lymphoblastic leukaemia relapsed to the CNS and resistant to conventional therapy. Br J Haematol (2009) 144:794-5. doi:10.1111/j.1365-2141.2008.07497.x.
    • (2009) Br J Haematol , vol.144 , pp. 794-795
    • Jaime-Perez, J.C.1    Rodriguez-Romo, L.N.2    Gonzalez-Llano, O.3    Chapa-Rodriguez, A.4    Gomez-Almaguer, D.5
  • 79
    • 84899493381 scopus 로고    scopus 로고
    • SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia
    • doi:10.1111/bjh.12778.
    • Advani AS, Mcdonough S, Coutre S, Wood B, Radich J, Mims M, et al. SWOG S0910: a phase 2 trial of clofarabine/cytarabine/epratuzumab for relapsed/refractory acute lymphocytic leukaemia. Br J Haematol (2014). doi:10.1111/bjh.12778.
    • (2014) Br J Haematol
    • Advani, A.S.1    Mcdonough, S.2    Coutre, S.3    Wood, B.4    Radich, J.5    Mims, M.6


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