메뉴 건너뛰기




Volumn 34, Issue 21, 2014, Pages 7383-7393

Genetic, cellular, and functional evidence for ca2+ inflow through cav1.2 and cav1.3 channels in murine spiral ganglion neurons

Author keywords

Action potentials; Calcium channels; Deafness; Hearing; Neuronal degeneration; Neuronal survival

Indexed keywords

CALCIUM CHANNEL; SHORT HAIRPIN RNA;

EID: 84901036318     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.5416-13.2014     Document Type: Article
Times cited : (17)

References (53)
  • 1
    • 0010452459 scopus 로고
    • Nitrendipine block of cardiac calcium channels: Highaffinity binding to the inactivated state
    • CrossRef Medline
    • Bean BP (1984) Nitrendipine block of cardiac calcium channels: highaffinity binding to the inactivated state. Proc Natl Acad Sci U S A 81: 6388-6392. CrossRef Medline
    • (1984) Proc Natl Acad Sci U S A , vol.81 , pp. 6388-6392
    • Bean, B.P.1
  • 3
    • 0032533732 scopus 로고    scopus 로고
    • Facilitation of presynaptic calcium currents in the rat brainstem
    • CrossRef Medline
    • Borst JG, Sakmann B (1998) Facilitation of presynaptic calcium currents in the rat brainstem. J Physiol 513:149-155. CrossRef Medline
    • (1998) J Physiol , vol.513 , pp. 149-155
    • Borst, J.G.1    Sakmann, B.2
  • 4
    • 78049518485 scopus 로고    scopus 로고
    • Auditory nerve fibers excite targets through synapses that vary in convergence, strength, and short-term plasticity
    • CrossRef Medline
    • Cao XJ, Oertel D (2010) Auditory nerve fibers excite targets through synapses that vary in convergence, strength, and short-term plasticity. J Neurophysiol 104:2308-2320. CrossRef Medline
    • (2010) J Neurophysiol , vol.104 , pp. 2308-2320
    • Cao, X.J.1    Oertel, D.2
  • 5
    • 24744440758 scopus 로고    scopus 로고
    • Developmental activation of calmodulin-dependent facilitation of cerebellar P-type Ca2 current
    • CrossRef Medline
    • Chaudhuri D, Alseikhan BA, Chang SY, Soong TW, Yue DT (2005) Developmental activation of calmodulin-dependent facilitation of cerebellar P-type Ca2 current. J Neurosci 25:8282-8294. CrossRef Medline
    • (2005) J Neurosci , vol.25 , pp. 8282-8294
    • Chaudhuri, D.1    Alseikhan, B.A.2    Chang, S.Y.3    Soong, T.W.4    Yue, D.T.5
  • 6
    • 79960988382 scopus 로고    scopus 로고
    • Complex distribution patterns of voltage-gated calcium channel alpha-subunits in the spiral ganglion
    • CrossRef Medline
    • Chen WC, Xue HZ, Hsu YL, Liu Q, Patel S, Davis RL (2011) Complex distribution patterns of voltage-gated calcium channel alpha-subunits in the spiral ganglion. Hear Res 278:52-68. CrossRef Medline
    • (2011) Hear Res , vol.278 , pp. 52-68
    • Chen, W.C.1    Xue, H.Z.2    Hsu, Y.L.3    Liu, Q.4    Patel, S.5    Davis, R.L.6
  • 8
    • 0028985125 scopus 로고
    • Exocytotic Ca2 channels in mammalian central neurons
    • CrossRef Medline
    • Dunlap K, Luebke JI, Turner TJ (1995) Exocytotic Ca2 channels in mammalian central neurons. Trends Neurosci 18:89-98. CrossRef Medline
    • (1995) Trends Neurosci , vol.18 , pp. 89-98
    • Dunlap, K.1    Luebke, J.I.2    Turner, T.J.3
  • 9
    • 0029014667 scopus 로고
    • Complementary roles of BDNF and NT-3 in vestibular and auditory development
    • CrossRef Medline
    • Ernfors P, Van De Water T, Loring J, Jaenisch R (1995) Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron 14:1153-1164. CrossRef Medline
    • (1995) Neuron , vol.14 , pp. 1153-1164
    • Ernfors, P.1    Van De Water, T.2    Loring, J.3    Jaenisch, R.4
  • 10
    • 0028322183 scopus 로고
    • Severe sensory and sympathetic deficits in mice lacking neurotrophin-3
    • CrossRef Medline
    • Fariñas I, Jones KR, Backus C, Wang XY, Reichardt LF (1994) Severe sensory and sympathetic deficits in mice lacking neurotrophin-3. Nature 369:658-661. CrossRef Medline
    • (1994) Nature , vol.369 , pp. 658-661
    • Fariñas, I.1    Jones, K.R.2    Backus, C.3    Wang, X.Y.4    Reichardt, L.F.5
  • 11
    • 0033046855 scopus 로고    scopus 로고
    • Making and breaking the innervation of the ear: Neurotrophic support during ear development and its clinical implications
    • CrossRef Medline
    • Fritzsch B, Pirvola U, Ylikoski J (1999) Making and breaking the innervation of the ear: neurotrophic support during ear development and its clinical implications. Cell Tissue Res 295:369-382. CrossRef Medline
    • (1999) Cell Tissue Res , vol.295 , pp. 369-382
    • Fritzsch, B.1    Pirvola, U.2    Ylikoski, J.3
  • 12
    • 33750433556 scopus 로고    scopus 로고
    • The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor
    • CrossRef Medline
    • Gomez-Ospina N, Tsuruta F, Barreto-Chang O, Hu L, Dolmetsch R (2006) The C terminus of the L-type voltage-gated calcium channel Ca(V)1.2 encodes a transcription factor. Cell 127:591-606. CrossRef Medline
    • (2006) Cell , vol.127 , pp. 591-606
    • Gomez-Ospina, N.1    Tsuruta, F.2    Barreto-Chang, O.3    Hu, L.4    Dolmetsch, R.5
  • 13
    • 0019441262 scopus 로고
    • Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches
    • CrossRef, Medline
    • Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ (1981) Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflugers Arch 391:85-100. CrossRef Medline
    • (1981) Pflugers Arch , vol.391 , pp. 85-100
    • Hamill, O.P.1    Marty, A.2    Neher, E.3    Sakmann, B.4    Sigworth, F.J.5
  • 14
    • 0031016231 scopus 로고    scopus 로고
    • Trophic support of cultured spiral ganglion neurons by depolarization exceeds and is additive with that by neurotrophins or cAMP and requires elevation of [Ca2 ]i within a set range
    • Medline
    • Hegarty JL, Kay AR, Green SH (1997) Trophic support of cultured spiral ganglion neurons by depolarization exceeds and is additive with that by neurotrophins or cAMP and requires elevation of [Ca2 ]i within a set range. J Neurosci 17:1959-1970. Medline
    • (1997) J Neurosci , vol.17 , pp. 1959-1970
    • Hegarty, J.L.1    Kay, A.R.2    Green, S.H.3
  • 15
    • 0029415003 scopus 로고
    • Voltage-dependent Ca2 channels in the spiral ganglion cells of guinea pig cochlea
    • CrossRef Medline
    • Hisashi K, Nakagawa T, Yasuda T, Kimitsuki T, Komune S, Komiyama S (1995) Voltage-dependent Ca2 channels in the spiral ganglion cells of guinea pig cochlea. Hear Res 91:196-201. CrossRef Medline
    • (1995) Hear Res , vol.91 , pp. 196-201
    • Hisashi, K.1    Nakagawa, T.2    Yasuda, T.3    Kimitsuki, T.4    Komune, S.5    Komiyama, S.6
  • 16
    • 77956570239 scopus 로고    scopus 로고
    • Dynamic spike thresholds during synaptic integration preserve and enhance temporal response properties in the avian cochlear nucleus
    • CrossRef Medline
    • Howard MA, Rubel EW (2010) Dynamic spike thresholds during synaptic integration preserve and enhance temporal response properties in the avian cochlear nucleus. J Neurosci 30:12063-12074. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 12063-12074
    • Howard, M.A.1    Rubel, E.W.2
  • 17
    • 0026613015 scopus 로고
    • Submicroscopic Ca2 diffusion mediates inhibitory coupling between individual Ca2 channels
    • CrossRef Medline
    • Imredy JP, Yue DT (1992) Submicroscopic Ca2 diffusion mediates inhibitory coupling between individual Ca2 channels. Neuron 9:197-207. CrossRef Medline
    • (1992) Neuron , vol.9 , pp. 197-207
    • Imredy, J.P.1    Yue, D.T.2
  • 18
    • 0028179582 scopus 로고
    • Mechanism of Ca(2)-sensitive inactivation of L-type Ca2 channels
    • CrossRef Medline
    • Imredy JP, Yue DT (1994) Mechanism of Ca(2)-sensitive inactivation of L-type Ca2 channels. Neuron 12:1301-1318. CrossRef Medline
    • (1994) Neuron , vol.12 , pp. 1301-1318
    • Imredy, J.P.1    Yue, D.T.2
  • 19
    • 0033523683 scopus 로고    scopus 로고
    • Chronic electrical stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness
    • CrossRef Medline
    • Leake PA, Hradek GT, Snyder RL (1999) Chronic electrical stimulation by a cochlear implant promotes survival of spiral ganglion neurons after neonatal deafness. J Comp Neurol 412:543-562. CrossRef Medline
    • (1999) J Comp Neurol , vol.412 , pp. 543-562
    • Leake, P.A.1    Hradek, G.T.2    Snyder, R.L.3
  • 20
    • 0028213606 scopus 로고
    • Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro
    • CrossRef Medline
    • Lefebvre PP, Malgrange B, Staecker H, Moghadass M, Van de Water TR, Moonen G (1994) Neurotrophins affect survival and neuritogenesis by adult injured auditory neurons in vitro. Neuroreport 5:865-868. CrossRef Medline
    • (1994) Neuroreport , vol.5 , pp. 865-868
    • Lefebvre, P.P.1    Malgrange, B.2    Staecker, H.3    Moghadass, M.4    Van de Water, T.R.5    Moonen, G.6
  • 21
  • 23
    • 78049413504 scopus 로고    scopus 로고
    • Kv7-type channel currents in spiral ganglion neurons: Involvement in sensorineural hearing loss
    • CrossRef Medline
    • Lv P, Wei D, Yamoah EN (2010) Kv7-type channel currents in spiral ganglion neurons: involvement in sensorineural hearing loss. J Biol Chem 285:34699-34707. CrossRef Medline
    • (2010) J Biol Chem , vol.285 , pp. 34699-34707
    • Lv, P.1    Wei, D.2    Yamoah, E.N.3
  • 24
    • 84869036507 scopus 로고    scopus 로고
    • Posthearing Ca(2) currents and their roles in shaping the different modes of firing of spiral ganglion neurons
    • CrossRef Medline
    • Lv P, Sihn CR, Wang W, Shen H, Kim HJ, Rocha-Sanchez SM, Yamoah EN (2012) Posthearing Ca(2) currents and their roles in shaping the different modes of firing of spiral ganglion neurons. J Neurosci 32:16314-16330. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 16314-16330
    • Lv, P.1    Sihn, C.R.2    Wang, W.3    Shen, H.4    Kim, H.J.5    Rocha-Sanchez, S.M.6    Yamoah, E.N.7
  • 25
    • 0032578634 scopus 로고    scopus 로고
    • Selective activation of Ca2-activated K channels by colocalized Ca2 channels in hippocampal neurons
    • CrossRef Medline
    • Marrion NV, Tavalin SJ (1998) Selective activation of Ca2-activated K channels by colocalized Ca2 channels in hippocampal neurons. Nature 395:900-905. CrossRef Medline
    • (1998) Nature , vol.395 , pp. 900-905
    • Marrion, N.V.1    Tavalin, S.J.2
  • 28
    • 0031106740 scopus 로고    scopus 로고
    • Effects of chronic high-rate electrical stimulation on the cochlea and eighth nerve in the deafened guinea pig
    • CrossRef Medline
    • Mitchell A, Miller JM, Finger PA, Heller JW, Raphael Y, Altschuler RA (1997) Effects of chronic high-rate electrical stimulation on the cochlea and eighth nerve in the deafened guinea pig. Hear Res 105:30-43. CrossRef Medline
    • (1997) Hear Res , vol.105 , pp. 30-43
    • Mitchell, A.1    Miller, J.M.2    Finger, P.A.3    Heller, J.W.4    Raphael, Y.5    Altschuler, R.A.6
  • 29
    • 38149027701 scopus 로고    scopus 로고
    • Regulation of presynaptic Ca(V)2.1 channels by Ca2 sensor proteins mediates short-term synaptic plasticity
    • CrossRef Medline
    • Mochida S, Few AP, Scheuer T, Catterall WA (2008) Regulation of presynaptic Ca(V)2.1 channels by Ca2 sensor proteins mediates short-term synaptic plasticity. Neuron 57:210-216. CrossRef Medline
    • (2008) Neuron , vol.57 , pp. 210-216
    • Mochida, S.1    Few, A.P.2    Scheuer, T.3    Catterall, W.A.4
  • 31
    • 0028292145 scopus 로고
    • Calcium channel diversity and neurotransmitter release: The omega-conotoxins and omega-agatoxins
    • CrossRef Medline
    • Olivera BM, Miljanich GP, Ramachandran J, Adams ME (1994) Calcium channel diversity and neurotransmitter release: the omega-conotoxins and omega-agatoxins. Annu Rev Biochem 63:823-867. CrossRef Medline
    • (1994) Annu Rev Biochem , vol.63 , pp. 823-867
    • Olivera, B.M.1    Miljanich, G.P.2    Ramachandran, J.3    Adams, M.E.4
  • 32
    • 0034616911 scopus 로고    scopus 로고
    • Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2 channels
    • CrossRef Medline
    • Platzer J, Engel J, Schrott-Fischer A, Stephan K, Bova S, Chen H, Zheng H, Striessnig J (2000) Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2 channels. Cell 102:89-97. CrossRef Medline
    • (2000) Cell , vol.102 , pp. 89-97
    • Platzer, J.1    Engel, J.2    Schrott-Fischer, A.3    Stephan, K.4    Bova, S.5    Chen, H.6    Zheng, H.7    Striessnig, J.8
  • 33
    • 0030964099 scopus 로고    scopus 로고
    • Either N-or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses
    • CrossRef Medline
    • Poncer JC, McKinney RA, Gähwiler BH, Thompson SM (1997) Either N-or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses. Neuron 18:463-472. CrossRef Medline
    • (1997) Neuron , vol.18 , pp. 463-472
    • Poncer, J.C.1    McKinney, R.A.2    Gähwiler, B.H.3    Thompson, S.M.4
  • 34
    • 0035426071 scopus 로고    scopus 로고
    • Direct measurement of singlechannel Ca(2) currents in bullfrog hair cells reveals two distinct channel subtype s
    • CrossRef Medline
    • Rodriguez-Contreras A, Yamoah EN (2001) Direct measurement of singlechannel Ca(2) currents in bullfrog hair cells reveals two distinct channel subtype s. J Physiol 534:669-689. CrossRef Medline
    • (2001) J Physiol , vol.534 , pp. 669-689
    • Rodriguez-Contreras, A.1    Yamoah, E.N.2
  • 35
    • 0037622107 scopus 로고    scopus 로고
    • Effects of permeant ion concentrations on the gating of L-type Ca2 channels in hair cells
    • CrossRef Medline
    • Rodríguez-Contreras A, Yamoah EN (2003) Effects of permeant ion concentrations on the gating of L-type Ca2 channels in hair cells. Biophys J 84:3457-3469. CrossRef Medline
    • (2003) Biophys J , vol.84 , pp. 3457-3469
    • Rodríguez-Contreras, A.1    Yamoah, E.N.2
  • 36
    • 0036462595 scopus 로고    scopus 로고
    • Ca2 transport properties and determinants of anomalous mole fraction effects of single voltage-gated Ca2 channels in hair cells from bullfrog saccule
    • CrossRef Medline
    • Rodriguez-Contreras A, Nonner W, Yamoah EN (2002) Ca2 transport properties and determinants of anomalous mole fraction effects of single voltage-gated Ca2 channels in hair cells from bullfrog saccule. J Physiol 538:729-745. CrossRef Medline
    • (2002) J Physiol , vol.538 , pp. 729-745
    • Rodriguez-Contreras, A.1    Nonner, W.2    Yamoah, E.N.3
  • 37
    • 57349187633 scopus 로고    scopus 로고
    • Effects of strontium on the permeation and gating phenotype of calcium channels in hair cells
    • CrossRef Medline
    • Rodriguez-Contreras A, Lv P, Zhu J, Kim HJ, Yamoah EN (2008) Effects of strontium on the permeation and gating phenotype of calcium channels in hair cells. J Neurophysiol 100:2115-2124. CrossRef Medline
    • (2008) J Neurophysiol , vol.100 , pp. 2115-2124
    • Rodriguez-Contreras, A.1    Lv, P.2    Zhu, J.3    Kim, H.J.4    Yamoah, E.N.5
  • 38
    • 38649113205 scopus 로고    scopus 로고
    • Membrane depolarization inhibits spiral ganglion neurite growth via activation of multiple types of voltage sensitive calcium channels and calpain
    • CrossRef Medline
    • Roehm PC, Xu N, Woodson EA, Green SH, Hansen MR (2008) Membrane depolarization inhibits spiral ganglion neurite growth via activation of multiple types of voltage sensitive calcium channels and calpain. Mol Cell Neurosci 37:376-387. CrossRef Medline
    • (2008) Mol Cell Neurosci , vol.37 , pp. 376-387
    • Roehm, P.C.1    Xu, N.2    Woodson, E.A.3    Green, S.H.4    Hansen, M.R.5
  • 39
    • 0036305336 scopus 로고    scopus 로고
    • Auditory system development: Primary auditory neurons and their targets
    • CrossRef Medline
    • Rubel EW, Fritzsch B (2002) Auditory system development: primary auditory neurons and their targets. Annu Rev Neurosci 25:51-101. CrossRef Medline
    • (2002) Annu Rev Neurosci , vol.25 , pp. 51-101
    • Rubel, E.W.1    Fritzsch, B.2
  • 40
    • 84859318083 scopus 로고    scopus 로고
    • Spike encoding of neurotransmitter release timing by spiral ganglion neurons of the cochlea
    • CrossRef Medline
    • Rutherford MA, Chapochnikov NM, Moser T (2012) Spike encoding of neurotransmitter release timing by spiral ganglion neurons of the cochlea. J Neurosci 32:4773-4789. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 4773-4789
    • Rutherford, M.A.1    Chapochnikov, N.M.2    Moser, T.3
  • 41
    • 0038380656 scopus 로고    scopus 로고
    • Biophysical and pharmacological characterization of voltage-gated calcium currents in turtle auditory hair cells
    • CrossRef Medline
    • Schnee ME, Ricci AJ (2003) Biophysical and pharmacological characterization of voltage-gated calcium currents in turtle auditory hair cells. J Physiol 549:697-717. CrossRef Medline
    • (2003) J Physiol , vol.549 , pp. 697-717
    • Schnee, M.E.1    Ricci, A.J.2
  • 42
    • 45449100752 scopus 로고    scopus 로고
    • Mechanism of local and global Ca2 sensing by calmodulin in complex with a Ca2 channel
    • CrossRef Medline
    • Tadross MR, Dick IE, Yue DT (2008) Mechanism of local and global Ca2 sensing by calmodulin in complex with a Ca2 channel. Cell 133:1228-1240. CrossRef Medline
    • (2008) Cell , vol.133 , pp. 1228-1240
    • Tadross, M.R.1    Dick, I.E.2    Yue, D.T.3
  • 43
    • 0031409370 scopus 로고    scopus 로고
    • Cellular mechanisms for preservation of timing in central auditory pathways
    • CrossRef Medline
    • Trussell LO (1997) Cellular mechanisms for preservation of timing in central auditory pathways. Curr Opin Neurobiol 7:487-492. CrossRef Medline
    • (1997) Curr Opin Neurobiol , vol.7 , pp. 487-492
    • Trussell, L.O.1
  • 44
    • 0142094664 scopus 로고    scopus 로고
    • Localization of the calcium channel subunits Cav1.2 (alpha1C) and Cav2.3 (alpha1E) in the mouse organ of Corti
    • Medline
    • Waka N, Knipper M, Engel J (2003) Localization of the calcium channel subunits Cav1.2 (alpha1C) and Cav2.3 (alpha1E) in the mouse organ of Corti. Histol Histopathol 18:1115-1123. Medline
    • (2003) Histol Histopathol , vol.18 , pp. 1115-1123
    • Waka, N.1    Knipper, M.2    Engel, J.3
  • 45
    • 34548618808 scopus 로고    scopus 로고
    • Survival, synaptogenesis, and regeneration of adult mouse spiral ganglion neurons in vitro
    • CrossRef Medline
    • Wei D, Jin Z, Järlebark L, Scarfone E, Ulfendahl M (2007) Survival, synaptogenesis, and regeneration of adult mouse spiral ganglion neurons in vitro. Dev Neurobiol 67:108-122. CrossRef Medline
    • (2007) Dev Neurobiol , vol.67 , pp. 108-122
    • Wei, D.1    Jin, Z.2    Järlebark, L.3    Scarfone, E.4    Ulfendahl, M.5
  • 46
    • 58549103703 scopus 로고    scopus 로고
    • Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage
    • Wei D, Levic S, Nie L, Gao WQ, Petit C, Jones EG, Yamoah EN (2008) Cells of adult brain germinal zone have properties akin to hair cells and can be used to replace inner ear sensory cells after damage. Proc Natl Acad Sci USA105:21000-21005.
    • (2008) Proc Natl Acad Sci USA105 , pp. 21000-21005
    • Wei, D.1    Levic, S.2    Nie, L.3    Gao, W.Q.4    Petit, C.5    Jones, E.G.6    Yamoah, E.N.7
  • 48
    • 0028258190 scopus 로고
    • Roles of N-type and Q-type Ca2 channels in supporting hippocampal synaptic transmission
    • CrossRef Medline
    • Wheeler DB, Randall A, Tsien RW (1994) Roles of N-type and Q-type Ca2 channels in supporting hippocampal synaptic transmission. Science 264: 107-111. CrossRef Medline
    • (1994) Science , vol.264 , pp. 107-111
    • Wheeler, D.B.1    Randall, A.2    Tsien, R.W.3
  • 49
    • 20444373044 scopus 로고    scopus 로고
    • The decrease in the presynaptic calcium current is a major cause of short-term depression at a calyx-type synapse
    • CrossRef Medline
    • Xu J, Wu LG (2005) The decrease in the presynaptic calcium current is a major cause of short-term depression at a calyx-type synapse. Neuron 46:633-645. CrossRef Medline
    • (2005) Neuron , vol.46 , pp. 633-645
    • Xu, J.1    Wu, L.G.2
  • 50
    • 0035882358 scopus 로고    scopus 로고
    • Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines
    • Medline
    • Xu W, Lipscombe D (2001) Neuronal Ca(V)1.3alpha(1) L-type channels activate at relatively hyperpolarized membrane potentials and are incompletely inhibited by dihydropyridines. J Neurosci 21:5944-5951. Medline
    • (2001) J Neurosci , vol.21 , pp. 5944-5951
    • Xu, W.1    Lipscombe, D.2
  • 52
    • 0037123934 scopus 로고    scopus 로고
    • (v)1.3 (alpha(1D)) calcium channel in sinoatrial nodes: Insight gained using gene-targeted null mutant mice
    • CrossRef Medline
    • Zhang Z, Xu Y, Song H, Rodriguez J, Tuteja D, Namkung Y, Shin HS, Chiamvimonvat N (2002) Functional Roles of Ca(v)1.3 (alpha(1D)) calcium channel in sinoatrial nodes: insight gained using gene-targeted null mutant mice. Circ Res 90:981-987. CrossRef Medline
    • (2002) Circ Res , vol.90 , pp. 981-987
    • Zhang, Z.1    Xu, Y.2    Song, H.3    Rodriguez, J.4    Tuteja, D.5    Namkung, Y.6    Shin, H.S.7    Chiamvimonvat, N.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.