Cellular mechanisms for preservation of timing in central auditory pathways

Current Opinion in Neurobiology

Volumn 7, Issue 4, 1997, Pages 487-492

  Trussell, Laurence O ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMIC ACID; NEUROTRANSMITTER; NEUROTRANSMITTER RECEPTOR; POTASSIUM; POTASSIUM CHANNEL;

ACOUSTIC NERVE FIBER; AUDITORY NERVOUS SYSTEM; BRAIN STEM; CHANNEL GATING; HUMAN; NERVE CELL PLASTICITY; NEUROBIOLOGY; NEUROTRANSMITTER RELEASE; PRIORITY JOURNAL; REVIEW;

EID: 0031409370     PISSN: 09594388     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0959-4388(97)80027-X     Document Type: Article

References (49)

1. Oertel D. The role of intrinsic neuronal properties in the encoding of auditory information in the cochlear nuclei. Curr Opin Neurobiol. 1:1991;221-228.
2. Carr CE. Processing of temporal informaton in the brain. Annu Rev Neurosci. 16:1993;223-243.
3. Joris PX, Carney LH, Smith PH, Yin TCT. Enhancement of neural synchronization in the anteroventral cochlear nucleus. I. Responses to tones at the characteristic frequency. J Neurophysiol. 71:1994;1022-1036.
4. Zhang S, Trussell LO. A characterization of excitatory postsynaptic potentials in the avian nucleus magnocellularis. J Neurophysiol. 72:1994;705-718.
5. Reyes AD, Rubel EW, Spain WJ. In vitro analysis of optimal stimuli for phase-locking and time-delayed modulation of firing in avian nucleus laminaris neurons. of special interest J Neurosci. 16:1996;993-1007 The authors examined the intrinsic and synaptic properties of nucleus laminaris neurons, which are auditory coincidenc detectors. They activated neurons with 'conductance clamp', synaptic-like waveforms to explore optimal convergence and the synaptic strength required to account for detection of interaural timing differences.
6. Oertel D. Synaptic responses and electrical properties of cells in brain slices of the mouse anteroventral cochlear nucleus. J Neurosci. 3:1983;2043-2053.
7. Golding NL, Robertson D, Oertel D. Recordings from slices indicate that octopous cells of the cochlear nucleus detect coincident firing of auditory nerve fibers with temporal precision. J Neurosci. 15:1995;3138-3153.
8. Banks MI, Smith PH. Intracellular recordings from neurobiotin-labeled cells in brain slices of the rat medial nucleus of the trapezoid body. J Neurosci. 12:1992;2819-2837.
9. Wu SH, Kelly JB. Physiological properties of neurons in the mouse superior olive: membrane characteristics and postsynaptic responses studies in vitro. J Neurophysiol. 65:1991;230-246.
10. Smith PH. Structural and functional differences distinguish principal from nonprincipal cells in the guinea pig MSO slice. J Neurophysiol. 73:1995;1653-1667.
11. Zhang S, Trussell LO. Voltage clamp analysis of excitatory synaptic transmission in the avian nucleus magnocellularis. J Physiol. 480:1994;123-136.
12. Barnes-Davies M, Forsythe ID. Pre- and postsynaptic glutamate receptors at a giant excitatory synapse in rat auditory brainstem slices. J Physiol. 488:1995;387-406.
13. Borst JG, Helmchen F, Sakmann B. Pre- and postsynaptic whole-cell recordings in the medial nucleus of the trapezoid body of the rat. J Physiol. 489:1995;825-840.
14. Isaacson JS, Walmsley B. Receptors underlying excitatory synaptic transmission in slices of the rat anteroventral cochlear nucleus. J Neurophysiol. 73:1995;964-973.
15. Raman IM, Trussell LO. The kinetics of the response to glutamate and kainate in neurons of the avian cochlear nucleus. Neuron. 9:1992;173-186.
16. Raman IM, Zhang S, Trussell LO. Pathway-specific expression of AMPA receptors and their contribution to neuronal signalling. J Neurosci. 14:1994;4998-5010.
17. ++ permeability of AMPA receptors in principal cells and interneurons in rat CNS. Neuron. 15:1995;193-204.
18. Partin KM, Fleck MW, Mayer ML. AMPA receptor flip/flop mutants affecting deactivation, desensitization, and modulation by cyclothiazide, aniracetam, and thiocyanate. J Neurosci. 16:1996;6634-6647.
19. Otis TS, Wu YC, Trussell LO. Delayed clearance of transmitter and the role of glutamate uptake at synapses with multiple release sites. of special interest J Neurosci. 16:1996;1633-1643 The authors demonstrate that end-bulb synapses cannot clear transmitter quickly, supporting the hypothesis that desensitization may regulate synaptic strength. They also show that glutamate transporters play a key role in removing glutamate from the synaptic cleft.
20. Mosbacher J, Schoepfer R, Monyer H, Burnashev N, Seeburg PH, Ruppersberg JP. A molecular determinant for submillisecond desensitization in glutamate receptors. Science. 266:1994;1059-1062.
21. Hunter C, Petralia RS, Vu T, Wenthold RJ. Expression of AMPA-selective glutamate receptor subunits in morphologically defined neurons of the mammalian cochlear nucleus. J Neurosci. 13:1993;1932-1946.
22. Sato K, Kiyama H, Tohyama M. The differential expression patterns of messenger RNAs encoding non-N-methyl-D-aspartate glutamate receptor subunits (GluR1-4) in the rat brain. Neuroscience. 52:1993;515-539.
23. Levin MD, Kubke MF, Schneider M, Wenthold R, Carr CE. Localization of AMPA-selective glutamate receptors in the auditory brainstem of the barn owl. of special interest J Comp Neurol. 378:1997;239-253 Immunostaining by AMPA receptor subunit specific antibodies was used to determine the distribution of different forms of AMPA receptor in different regions of the lower auditory pathways of the owl. The authors provide an excellent discussion relating the expression pattern to the role of various cells in information processing, drawing on a wealth of knowledge about the functional significance of different regions of the avian auditory brainstem and midbrain.
24. ++ permeability mediate synaptic transmission in the auditory pathway. J Physiol. 482:1995;309-315.
25. Zhou N, Taylor DA, Parks TN. Cobalt-permeable non-NMDA receptors in developing chick brainstem auditory nuclei. Neuroreport. 6:1995;2273-2276.
26. Reyes AD, Rubel EW, Spain WJ. Membrane properties underlying the firing of neurons in the avian cochlear nucleus. J Neurosci. 14:1994;5352-5364.
27. Manis PB, Marx SO. Outward currents in isolated ventral cochlear nucleus neurons. J Neurosci. 11:1991;2865-2880.
28. Forsythe ID, Barnes-Davies M. The binaural auditory pathway: membrane currents limiting multiple action potential generation in the rat medial nucleus of the trapezoid body. Proc R Soc Lond (Biol). 251:1993;143-150.
29. Brew HM, Forsythe ID. Two voltage-dependent K conductances with complementary functions in postsynaptic integration at a central audory synapse. J Neurosci. 15:1995;8011-8022.
30. Grissmer S, Nguyen AN, Aiyar J, Hanson DC, Mather RJ, Gutman GA, Karmilowicz MJ, Auperion DD, Chandy KG. Pharmacological characterization of five cloned voltage-gated K channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines. Mol Pharmacol. 45:1994;1227-1234.
31. Wang H, Kunkel DD, Schwartzkroin PA, Tempel BL. Localization of Kv1.1 and Kv1.2, two K channel proteins, to synaptic terminals somata and dendrites in the mouse brain. J Neurosci. 14:1994;4588-4599.
32. Perney TM, Marshall J, Martin KA, Hockfield S, Kaczmarek LK. Expression of the mRNAs for the Kv3.1 potassium channel gene in the adult and developing rat brain. J Neurophysiol. 68:1992;756-766.
33. Weiser M, Bueno E, Sekirnak C, Martone ME, Baker H, Hillman D, Chane S, Thornhill W, Ellisman M, Rudy B. The potassium channel subunit KV3.1b is localized to somatic and axonal membranes of specific populations of CNS neurons. J Neurosci. 15:1994;4298-4314.
34. Kanemasa T, Gan L, Perney TM, Wang LY, Kaczmarek LK. Electrophysiological and pharmacological characterization of a mammalian Shaw channel expressed in NIH 3T3 fibroblasts. J Neurophysiol. 74:1995;207-217.
35. Sivaramakrishnan S, Laurent G. Pharmacological characterization of presynaptic calcium currents underlying glutamatergic transmission in the avian auditory brainstem. J Neurosci. 15:1995;6576-6585.
36. Borst JG, Sakmann B. Calcium influx and transmitter release in a fast CNS synapse. of special interest Nature. 383:1996;431-434 Simultaneous pre- and postsynaptic recordings from the large nerve terminal in the MNTB were used to determine the relationship among calcium influx, buffering and transmitter release. Introduction of calcium buffers into the nerve terminal reduced release, leading to the suggestion that the activity of multiple calcium channels is needed to evoke the release of each vesicle.
37. Takahashi T, Forsythe ID, Tsujimoto T, Barnes-Davies M, Onodera K. Presynaptic calcium current modulation by a metabotropic glutamate receptor. of special interest Science. 274:1996;594-597 Recordings from MNTB nerve terminal and postsynaptic neurons provided direct evidence that metabotropic glutamate receptors inhibit release by blocking a calcium current.
38. Helmchen F, Borst JG, Sakmann B. Calcium dynamics associated with a single action potential in a CNS presynaptic terminal. of outstanding interest Biophys J. 72:1997;1458-1471 The authors measured calcium buffering in MNTB nerve terminals. Calcium indicator dye introduced through a patch pipette permitted simultaneous measurement of the indicator signal and calcium current. The results suggest that buffering is of a relatively low capacity and that the calcium extrusion rate is high.
39. Sabatini BL, Regehr WG. Timing of neurotransmission at fast synapses in the mammalian brain. Nature. 384:1996;170-172.
40. Isaacson JS, Walmsley B. Counting quanta: direct measurements of transmitter release at a central synapse. Neuron. 15:1995;875-884.
41. Diamond JS, Jahr CE. Asynchronous release of synaptic vesicles determines the time course of the AMPA receptor-mediated EPSC. Neuron. 15:1995;1097-1107.
42. Otis TS, Trussell LO. Inhibition of transmitter release shortens the duration of the excitatory synaptic current at a calyceal synapse. J Neurophysiol. 76:1996;3584-3588.
43. Trussell LO, Zhang S, Raman IM. Desensitization of AMPA receptors upon multi-quantal neurotransmitter release. Neuron. 10:1993;1185-1196.
44. Otis TS, Zhang S, Trussell LO. Direct measurement of AMPA receptor desensitization induced by glutamatergic synaptic transmission. of outstanding interest J Neurosci. 16:1996;7496-7504 The first direct demonstration of AMPA receptor desensitization by endogenous glutamate. The authors provide evidence that desensitization contributes to synaptic depression at calyceal synapses.
45. Forsythe ID. Direct patch recording from identified presynaptic terminals mediating glutamatergic EPSCs in the rat CNS, in vitro. J Physiol. 479:1994;381-387.
46. Grothe B, Sanes DH. Synaptic inhibition influences the temporal coding properties of medial superior olivary neurons: an in vitro study. J Neurosci. 14:1994;1701-1709.
47. Wu SH, Kelly JB. Binaural interaction in the lateral superior olive: time difference sensitivity studied in mouse brain slice. J Neurophysiol. 68:1992;1151-1159.
48. Gan L, Perney TM, Kaczmarek LK. Cloning and characterization of the promoter for a potassium channel expressed in high frequency firing neurons. J Biol Chem. 271:1996;5859-5865.
49. Rubio ME, Wenthold RJ. Glutamatergic receptors are selectively targeted to postsynaptic sites in neurons. of outstanding interest Neuron. 18:1997;939-950 Fusiform cells of the dorsal cochlear nucleus receive spatially segregated glutamatergic synapses from auditory nerve and parallel fibers. These authors used electron microscopic immunostaining techniques on identified neurons to show that the two types of synapse feature different subtypes of ionotropic and metabotropic glutamate receptors. They speculate that this might occur through trafficking of the proteins into apical and basal dendrites.