Stability study of full-length antibody (anti-TNF alpha) loaded PLGA microspheres

International Journal of Pharmaceutics

Volumn 470, Issue 1-2, 2014, Pages 41-50

  Marquette, S ^a,b   Peerboom, C ^b   Yates, A ^b   Denis, L ^b   Langer, I ^a   Amighi, K ^a   Goole, J ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UCB PHARMA   (Belgium)

Author keywords

Antibody; Encapsulation; Microspheres; PLGA; Stability

Indexed keywords

LACTIC ACID; MICROSPHERE; MONOCLONAL ANTIBODY; OIL; POLYGLACTIN; RESOMER; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; TUMOR NECROSIS FACTOR ALPHA MONOCLONAL ANTIBODY; UNCLASSIFIED DRUG; WATER; POLYESTER; POLYGLYCOLIC ACID; POLYLACTIC ACID-POLYGLYCOLIC ACID COPOLYMER; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG STABILITY; DRUG STORAGE; EMULSION; ENTHALPY; FRAGMENTATION REACTION; GLASS TRANSITION TEMPERATURE; HUMIDITY; MICROENCAPSULATION; PARTICLE SIZE; PRIORITY JOURNAL; SOLID; SOLID IN OIL IN WATER EMULSION; SPRAY DRYING; STORAGE TEMPERATURE; ANIMAL; CHEMISTRY; IMMUNOLOGY; MOUSE; SOLUBILITY; TUMOR CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; DRUG STABILITY; LACTIC ACID; MICE; MICROSPHERES; PARTICLE SIZE; POLYESTERS; POLYGLYCOLIC ACID; SOLUBILITY; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84901022240     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2014.04.063     Document Type: Article

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