-
1
-
-
84899631957
-
The genetic basis of pulmonary arterial hypertension
-
Ma L, Chung WK. The genetic basis of pulmonary arterial hypertension. Hum Genet 2014;133:471-479.
-
(2014)
Hum Genet
, vol.133
, pp. 471-479
-
-
Ma, L.1
Chung, W.K.2
-
2
-
-
13444279874
-
Pathogenesis of pulmonary arterial hypertension: The need for multiple hits
-
Yuan JX, Rubin LJ. Pathogenesis of pulmonary arterial hypertension: the need for multiple hits. Circulation 2005;111:534-538.
-
(2005)
Circulation
, vol.111
, pp. 534-538
-
-
Yuan, J.X.1
Rubin, L.J.2
-
3
-
-
78349266116
-
Somatic mutations in pulmonary arterial hypertension: Primary or secondary events?
-
Austin ED, Hamid R, Ahmad F. Somatic mutations in pulmonary arterial hypertension: primary or secondary events? Am J Respir Crit Care Med 2010;182:1094-1096.
-
(2010)
Am J Respir Crit Care Med
, vol.182
, pp. 1094-1096
-
-
Austin, E.D.1
Hamid, R.2
Ahmad, F.3
-
4
-
-
84899804206
-
Functional prostacyclin synthase promoter polymorphisms: Impact in pulmonary arterial hypertension
-
Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, et al. Functional prostacyclin synthase promoter polymorphisms: impact in pulmonary arterial hypertension. Am J Respir Crit Care Med 2014;189: 1110-1120.
-
(2014)
Am J Respir Crit Care Med
, vol.189
, pp. 1110-1120
-
-
Stearman, R.S.1
Cornelius, A.R.2
Lu, X.3
Conklin, D.S.4
Del Rosario, M.J.5
Lowe, A.M.6
Elos, M.T.7
Fettig, L.M.8
Wong, R.E.9
Hara, N.10
-
5
-
-
33645529116
-
Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps
-
Poole EM, Bigler J, Whitton J, Sibert JG, Potter JD, Ulrich CM. Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps. Cancer Epidemiol Biomarkers Prev 2006;15:502-508.
-
(2006)
Cancer Epidemiol Biomarkers Prev
, vol.15
, pp. 502-508
-
-
Poole, E.M.1
Bigler, J.2
Whitton, J.3
Sibert, J.G.4
Potter, J.D.5
Ulrich, C.M.6
-
6
-
-
0032749227
-
Human prostacyclin synthase gene and hypertension: The Suita Study
-
Iwai N, Katsuya T, Ishikawa K, Mannami T, Ogata J, Higaki J, Ogihara T, Tanabe T, Baba S. Human prostacyclin synthase gene and hypertension: the Suita Study. Circulation 1999;100:2231-2236.
-
(1999)
Circulation
, vol.100
, pp. 2231-2236
-
-
Iwai, N.1
Katsuya, T.2
Ishikawa, K.3
Mannami, T.4
Ogata, J.5
Higaki, J.6
Ogihara, T.7
Tanabe, T.8
Baba, S.9
-
7
-
-
0030248632
-
Human gene encoding prostacyclin synthase (PTGIS): Genomic organization, chromosomal localization, and promoter activity
-
Yokoyama C, Yabuki T, Inoue H, Tone Y, Hara S, Hatae T, Nagata M, Takahashi EI, Tanabe T. Human gene encoding prostacyclin synthase (PTGIS): genomic organization, chromosomal localization, and promoter activity. Genomics 1996;36:296-304.
-
(1996)
Genomics
, vol.36
, pp. 296-304
-
-
Yokoyama, C.1
Yabuki, T.2
Inoue, H.3
Tone, Y.4
Hara, S.5
Hatae, T.6
Nagata, M.7
Takahashi, E.I.8
Tanabe, T.9
-
8
-
-
0032729325
-
Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension
-
Geraci MW, Gao B, Shepherd DC, Moore MD, Westcott JY, Fagan KA, Alger LA, Tuder RM, Voelkel NF. Pulmonary prostacyclin synthase overexpression in transgenic mice protects against development of hypoxic pulmonary hypertension. J Clin Invest 1999;103:1509-1515.
-
(1999)
J Clin Invest
, vol.103
, pp. 1509-1515
-
-
Geraci, M.W.1
Gao, B.2
Shepherd, D.C.3
Moore, M.D.4
Westcott, J.Y.5
Fagan, K.A.6
Alger, L.A.7
Tuder, R.M.8
Voelkel, N.F.9
-
9
-
-
84873647366
-
Pulmonary arterial hypertension: New insights into the optimal role of current and emerging prostacyclin therapies
-
quiz 17A-19A
-
Waxman AB, Zamanian RT. Pulmonary arterial hypertension: new insights into the optimal role of current and emerging prostacyclin therapies. Am J Cardiol 2013;111(5 Suppl):1A-16A, quiz 17A-19A.
-
(2013)
Am J Cardiol
, vol.111
, Issue.5 SUPPL.
-
-
Waxman, A.B.1
Zamanian, R.T.2
-
10
-
-
0033032949
-
Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension
-
Tuder RM, Cool CD, Geraci MW, Wang J, Abman SH, Wright L, Badesch D, Voelkel NF. Prostacyclin synthase expression is decreased in lungs from patients with severe pulmonary hypertension. Am J Respir Crit Care Med 1999;159:1925-1932.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 1925-1932
-
-
Tuder, R.M.1
Cool, C.D.2
Geraci, M.W.3
Wang, J.4
Abman, S.H.5
Wright, L.6
Badesch, D.7
Voelkel, N.F.8
-
11
-
-
71049187330
-
Alterations in oestrogen metabolism: Implications for higher penetrance of familial pulmonary arterial hypertension in females
-
Austin ED, Cogan JD, West JD, Hedges LK, Hamid R, Dawson EP, Wheeler LA, Parl FF, Loyd JE, Phillips JA III. Alterations in oestrogen metabolism: implications for higher penetrance of familial pulmonary arterial hypertension in females. Eur Respir J 2009;34:1093-1099.
-
(2009)
Eur Respir J
, vol.34
, pp. 1093-1099
-
-
Austin, E.D.1
Cogan, J.D.2
West, J.D.3
Hedges, L.K.4
Hamid, R.5
Dawson, E.P.6
Wheeler, L.A.7
Parl, F.F.8
Loyd, J.E.9
Phillips III, J.A.10
-
12
-
-
44449120433
-
Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension
-
Phillips JA III, Poling JS, Phillips CA, Stanton KC, Austin ED, Cogan JD, Wheeler L, Yu C, Newman JH, Dietz HC, et al. Synergistic heterozygosity for TGFbeta1 SNPs and BMPR2 mutations modulates the age at diagnosis and penetrance of familial pulmonary arterial hypertension. Genet Med 2008;10:359-365.
-
(2008)
Genet Med
, vol.10
, pp. 359-365
-
-
Phillips III, J.A.1
Poling, J.S.2
Phillips, C.A.3
Stanton, K.C.4
Austin, E.D.5
Cogan, J.D.6
Wheeler, L.7
Yu, C.8
Newman, J.H.9
Dietz, H.C.10
-
13
-
-
33645300735
-
Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension
-
Willers ED, Newman JH, Loyd JE, Robbins IM, Wheeler LA, Prince MA, Stanton KC, Cogan JA, Runo JR, Byrne D, et al. Serotonin transporter polymorphisms in familial and idiopathic pulmonary arterial hypertension. Am J Respir Crit Care Med 2006;173: 798-802.
-
(2006)
Am J Respir Crit Care Med
, vol.173
, pp. 798-802
-
-
Willers, E.D.1
Newman, J.H.2
Loyd, J.E.3
Robbins, I.M.4
Wheeler, L.A.5
Prince, M.A.6
Stanton, K.C.7
Cogan, J.A.8
Runo, J.R.9
Byrne, D.10
-
14
-
-
84878576691
-
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension
-
Germain M, Eyries M, Montani D, Poirier O, Girerd B, Dorfmüller P, Coulet F, Nadaud S, Maugenre S, Guignabert C, et al. Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension. Nat Genet 2013;45:518-521.
-
(2013)
Nat Genet
, vol.45
, pp. 518-4521
-
-
Germain, M.1
Eyries, M.2
Montani, D.3
Poirier, O.4
Girerd, B.5
Dorfmüller, P.6
Coulet, F.7
Nadaud, S.8
Maugenre, S.9
Guignabert, C.10
-
15
-
-
34250618309
-
Function of Kv1.5 channels and genetic variations of KCNA5 in patients with idiopathic pulmonary arterial hypertension
-
Remillard CV, Tigno DD, Platoshyn O, Burg ED, Brevnova EE, Conger D, Nicholson A, Rana BK, Channick RN, Rubin LJ, et al. Function of Kv1.5 channels and genetic variations of KCNA5 in patients with idiopathic pulmonary arterial hypertension. Am J Physiol Cell Physiol 2007;292:C1837-C1853.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Remillard, C.V.1
Tigno, D.D.2
Platoshyn, O.3
Burg, E.D.4
Brevnova, E.E.5
Conger, D.6
Nicholson, A.7
Rana, B.K.8
Channick, R.N.9
Rubin, L.J.10
-
16
-
-
33748650330
-
Angiotensinconverting enzyme gene polymorphisms and prognosis in chronic thromboembolic pulmonary hypertension
-
Tanabe N, Amano S, Tatsumi K, Kominami S, Igarashi N, Shimura R, Matsubara H, Kasahara Y, Takiguchi Y, Kuriyama T. Angiotensinconverting enzyme gene polymorphisms and prognosis in chronic thromboembolic pulmonary hypertension. Circ J 2006;70: 1174-1179.
-
(2006)
Circ J
, vol.70
, pp. 1174-1179
-
-
Tanabe, N.1
Amano, S.2
Tatsumi, K.3
Kominami, S.4
Igarashi, N.5
Shimura, R.6
Matsubara, H.7
Kasahara, Y.8
Takiguchi, Y.9
Kuriyama, T.10
-
17
-
-
33747855532
-
Interleukin-6 gene polymorphism confers susceptibility to pulmonary hypertension in chronic obstructive pulmonary disease
-
Eddahibi S, Chaouat A, Tu L, Chouaid C, Weitzenblum E, Housset B, Maitre B, Adnot S. Interleukin-6 gene polymorphism confers susceptibility to pulmonary hypertension in chronic obstructive pulmonary disease. Proc Am Thorac Soc 2006;3:475-476.
-
(2006)
Proc Am Thorac Soc
, vol.3
, pp. 475-476
-
-
Eddahibi, S.1
Chaouat, A.2
Tu, L.3
Chouaid, C.4
Weitzenblum, E.5
Housset, B.6
Maitre, B.7
Adnot, S.8
-
18
-
-
84894475046
-
A conceptual review on systems biology in health and diseases: From biological networks to modern therapeutics
-
Somvanshi PR, Venkatesh KV. A conceptual review on systems biology in health and diseases: from biological networks to modern therapeutics. Syst Synth Biol 2014;8:99-116.
-
(2014)
Syst Synth Biol
, vol.8
, pp. 99-116
-
-
Somvanshi, P.R.1
Venkatesh, K.V.2
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