The influence of gender, age and treatment time on brain oxidative stress and memory impairment induced by D-galactose in mice

Neuroscience Letters

Volumn 571, Issue , 2014, Pages 45-49

  Hao, Ling ^a   Huang, Huang ^a   Gao, Junying ^a   Marshall, Charles ^b   Chen, Yali ^a   Xiao, Ming ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Brain aging; D Galactose; Mice; Oxidative stress; Spatial memory

Indexed keywords

GALACTOSE; HYDROXYL RADICAL; MALONALDEHYDE; REACTIVE OXYGEN METABOLITE;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN HOMOGENATE; BRAIN OXIDATIVE STRESS; CONTROLLED STUDY; FEMALE; LOCOMOTION; MALE; MEMORY DISORDER; MOUSE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CARBONYLATION; SCANNING ELECTRON MICROSCOPY; SEX DIFFERENCE; SPATIAL LEARNING; SPATIAL MEMORY; TIME TO TREATMENT; Y-MAZE TEST; AGING; ANIMAL; BRAIN; C57BL MOUSE; DRUG EFFECTS; MAZE TEST; METABOLISM; PSYCHOLOGY; TIME;

AGE FACTORS; AGING; ANIMALS; BRAIN; FEMALE; GALACTOSE; MALE; MAZE LEARNING; MICE, INBRED C57BL; MODELS, ANIMAL; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SEX FACTORS; SPATIAL MEMORY; TIME FACTORS;

EID: 84901018868     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2014.04.038     Document Type: Article

References (22)

1. Dröge W. Oxidative stress and aging. Adv. Exp. Med. Biol. 2003, 543:191-200.
2. Reynolds A., Laurie C., Mosley R.L., Gendelman H.E. Oxidative stress and the pathogenesis of neurodegenerative disorders. Int. Rev. Neurobiol. 2007, 82:297-325.
3. Lu J., Zheng Y.L., Wu D.M., Luo L., Sun D.X., Shan Q. Ursolic acid ameliorates cognition deficits and attenuates oxidative damage in the brain of senescent mice induced by d-galactose. Biochem. Pharmacol. 2007, 74:1078-1090.
4. Lei M., Su Y., Hua X., Ding J., Han Q., Hu G., Xiao M. Chronic systemic injection of d-galactose impairs the septohippocampal cholinergic system in rats. Neuroreport 2008, 19:1611-1615.
5. Wu D.M., Lu J., Zheng Y.L., Zhou Z., Shan Q., Ma D.F. Purple sweet potato color repairs d-galactose-induced spatial learning and memory impairment by regulating the expression of synaptic proteins. Neurobiol. Learn Mem. 2008, 90:19-27.
6. Luo Y., Niu F., Sun Z., Cao W., Zhang X., Guan D., Lv Z., Zhang B., Xu Y. Altered expression of Abeta metabolism-associated molecules from d-galactose/AlCl(3) induced mouse brain. Mech. Ageing Dev. 2009, 130:248-252.
7. Lei M., Hua X., Xiao M., Ding J., Han Q., Hu G. Impairments of astrocytes are involved in the d-galactose-induced brain aging. Biochem. Biophys. Res. Commun. 2008, 369:1082-1087.
8. Shan Q., Lu J., Zheng Y., Li J., Zhou Z., Hu B., Zhang Z., Fan S., Mao Z., Wang Y.J., Ma D. Purple sweet potato color ameliorates cognition deficits and attenuates oxidative damage and inflammation in aging mouse brain induced by d-galactose. J. Biomed. Biotechnol. 2009, 2009:564737.
9. Ji D.B., Ye J., Li C.L., Wang Y.H., Zhao J., Cai S.Q. Antiaging effect of Cordyceps sinensis extract. Phytother. Res. 2009, 23:116-122.
10. Wu W., Li M., Liu L., Gao J., Kong H., Ding J., Hu G., Xiao M. Astrocyte activation but not neuronal impairment occurs in the hippocampus of mice after 2 weeks of d-galactose exposure. Life Sci. 2011, 89:355-363.
11. Kumar A., Dogra S., Prakash A. Effect of carvedilol on behavioral, mitochondrial dysfunction, and oxidative damage against d-galactose induced senescence in mice. Naunyn Schmiedebergs Arch. Pharmacol. 2009, 380:431-441.
12. Parameshwaran K., Irwin M.H., Steliou K., Pinkert C.A. d-galactose effectiveness in modeling aging and therapeutic antioxidant treatment in mice. Rejuvenation Res. 2010, 13:729-735.
13. Chen C.F., Lang S.Y., Zuo P.P., Yang N., Wang X.Q., Xia C. Effects of d-galactose on the expression of hippocampal peripheral-type benzodiazepine receptor and spatial memory performances in rats. Psychoneuroendocrinology 2006, 31:805-811.
14. Lu J., Wu D.M., Zheng Y.L., Hu B., Zhang Z.F. Purple sweet potato color alleviates d-galactose-induced brain aging in old mice by promoting survival of neurons via PI3K pathway and inhibiting cytochrome C-mediated apoptosis. Brain Pathol. 2010, 20:598-612.
15. Wei H., Li L., Song Q., Ai H., Chu J., Li W. Behavioural study of the d-galactose induced aging model in C57BL/6J mice. Behav. Brain Res. 2005, 157:245-251.
16. Lu J., Wu D.M., Zheng Y.L., Hu B., Zhang Z.F., Ye Q., Liu C.M., Shan Q., Wang Y.J. Ursolic acid attenuates d-galactose-induced inflammatory response in mouse prefrontal cortex through inhibiting AGEs/RAGE/NF-kB pathway activation. Cereb. Cortex 2010, 20:2540-2548.
17. McCarthy M.M., Arnold A.P., Ball G.F., Blaustein J.D., De Vries G.J. Sex differences in the brain: the not so inconvenient truth. J. Neurosci. 2012, 32:2241-2247.
18. Manthey D., Behl C. From structural biochemistry to expression profiling: neuroprotective activities of estrogen. Neuroscience 2006, 138:845-850.
19. Hua X., Lei M., Zhang Y., Ding J., Han Q., Hu G., Xiao M. Long-term d-galactose injection combined with ovariectomy serves as a new rodent model for Alzheimer's disease. Life Sci. 2007, 80:1897-1905.
20. Giergiel M., Lopucki M., Stachowicz N., Kankofer M. The influence of age and gender on antioxidant enzyme activities in humans and laboratory animals. Aging Clin. Exp. Res. 2012, 24:561-569.
21. Xu Y., Wu T., Jin Y., Fu Z. Effects of age and jet lag on d-galactose induced aging process. Biogerontology 2009, 10:153-161.
22. Sofroniew M.V., Vinters H.V. Astrocytes: biology and pathology. Acta Neuropathol. 2010, 119:7-35.