메뉴 건너뛰기




Volumn 5, Issue FEB, 2014, Pages

In vitro spermatogenesis - optimal culture conditions for testicular cell survival, germ cell differentiation, and steroidogenesis in rats

Author keywords

Cell culture; Culture medium; Leydig cells; Spermatogenesis; Stem cell niche; Testis; Testosterone

Indexed keywords

ANDROGEN; BETA ACTIN; CARRIER PROTEIN; CYCLIC AMP RESPONSIVE ELEMENT MODULATOR; FLUORESCENT DYE; GLUTAMINE; GONADOTROPIN; MESSENGER RNA; PROTAMINE; STEM CELL FACTOR; STEROIDOGENIC ACUTE REGULATORY PROTEIN; TESTOSTERONE; ZINC FINGER PROTEIN;

EID: 84901018468     PISSN: None     EISSN: 16642392     Source Type: Journal    
DOI: 10.3389/fendo.2014.00021     Document Type: Article
Times cited : (40)

References (37)
  • 1
    • 0027451672 scopus 로고
    • Physiopathology of spermatogenic arrest
    • Martin-du Pan RC, Campana A. Physiopathology of spermatogenic arrest. Fertil Steril (1993) 60(6):937-46.
    • (1993) Fertil Steril , vol.60 , Issue.6 , pp. 937-946
    • Martin-du Pan, R.C.1    Campana, A.2
  • 2
    • 84870743660 scopus 로고    scopus 로고
    • Clinical review: present and future prospects of male fertility preservation for children and adolescents
    • doi:10.1210/jc.2012-3065
    • Jahnukainen K, Stukenborg JB. Clinical review: present and future prospects of male fertility preservation for children and adolescents. J Clin Endocrinol Metab (2012) 97(12):4341-51. doi:10.1210/jc.2012-3065.
    • (2012) J Clin Endocrinol Metab , vol.97 , Issue.12 , pp. 4341-4351
    • Jahnukainen, K.1    Stukenborg, J.B.2
  • 3
    • 79960630562 scopus 로고    scopus 로고
    • Current options for preservation of fertility in the male
    • doi:10.1016/j.fertnstert.2011.06.028
    • Holoch P, Wald M. Current options for preservation of fertility in the male. Fertil Steril (2011) 96(2):286-90. doi:10.1016/j.fertnstert.2011.06.028.
    • (2011) Fertil Steril , vol.96 , Issue.2 , pp. 286-290
    • Holoch, P.1    Wald, M.2
  • 4
    • 80053929415 scopus 로고    scopus 로고
    • Quality of health in survivors of childhood acute myeloid leukemia treated with chemotherapy only: a NOPHO-AML study
    • doi:10.1002/pbc.22931
    • Molgaard-Hansen L, Glosli H, Jahnukainen K, Jarfelt M, Jonmundsson GK, Malmros-Svennilson J, et al. Quality of health in survivors of childhood acute myeloid leukemia treated with chemotherapy only: a NOPHO-AML study. Pediatr Blood Cancer (2011) 57(7):1222-9. doi:10.1002/pbc.22931.
    • (2011) Pediatr Blood Cancer , vol.57 , Issue.7 , pp. 1222-1229
    • Molgaard-Hansen, L.1    Glosli, H.2    Jahnukainen, K.3    Jarfelt, M.4    Jonmundsson, G.K.5    Malmros-Svennilson, J.6
  • 5
    • 28044470973 scopus 로고    scopus 로고
    • Long-term outcomes of adult survivors of childhood cancer-results from the childhood cancer survivor study
    • doi:10.1002/cncr.21249
    • Robison LL, Green DM, Hudson M, Meadows AT, Mertens AC, Packer RJ, et al. Long-term outcomes of adult survivors of childhood cancer-results from the childhood cancer survivor study. Cancer (2005) 104(11):2557-64. doi:10.1002/cncr.21249.
    • (2005) Cancer , vol.104 , Issue.11 , pp. 2557-2564
    • Robison, L.L.1    Green, D.M.2    Hudson, M.3    Meadows, A.T.4    Mertens, A.C.5    Packer, R.J.6
  • 6
    • 69049109915 scopus 로고    scopus 로고
    • New horizons for in vitro spermatogenesis? An update on novel three-dimensional culture systems as tools for meiotic and post-meiotic differentiation of testicular germ cells
    • doi:10.1093/molehr/gap052
    • Stukenborg JB, Schlatt S, Simoni M, Yeung CH, Elhija MA, Luetjens CM, et al. New horizons for in vitro spermatogenesis? An update on novel three-dimensional culture systems as tools for meiotic and post-meiotic differentiation of testicular germ cells. Mol Hum Reprod (2009) 15(9):521-9. doi:10.1093/molehr/gap052.
    • (2009) Mol Hum Reprod , vol.15 , Issue.9 , pp. 521-529
    • Stukenborg, J.B.1    Schlatt, S.2    Simoni, M.3    Yeung, C.H.4    Elhija, M.A.5    Luetjens, C.M.6
  • 7
    • 43449103963 scopus 로고    scopus 로고
    • Coculture of spermatogonia with somatic cells in a novel three-dimensional soft-agar-culture-system
    • doi:10.2164/jandrol.107.002857
    • Stukenborg JB, Wistuba J, Luetjens CM, Elhija MA, Huleihel M, Lunenfeld E, et al. Coculture of spermatogonia with somatic cells in a novel three-dimensional soft-agar-culture-system. J Androl (2008) 29(3):312-29. doi:10.2164/jandrol.107.002857.
    • (2008) J Androl , vol.29 , Issue.3 , pp. 312-329
    • Stukenborg, J.B.1    Wistuba, J.2    Luetjens, C.M.3    Elhija, M.A.4    Huleihel, M.5    Lunenfeld, E.6
  • 8
    • 84858017936 scopus 로고    scopus 로고
    • Differentiation of murine male germ cells to spermatozoa in a soft agar culture system
    • doi:10.1038/aja.2011.112
    • Abu Elhija M, Lunenfeld E, Schlatt S, Huleihel M. Differentiation of murine male germ cells to spermatozoa in a soft agar culture system. Asian J Androl (2012) 14(2):285-93. doi:10.1038/aja.2011.112.
    • (2012) Asian J Androl , vol.14 , Issue.2 , pp. 285-293
    • Abu Elhija, M.1    Lunenfeld, E.2    Schlatt, S.3    Huleihel, M.4
  • 9
    • 6344237008 scopus 로고    scopus 로고
    • In vitro maturation of fresh and frozen-thawed mouse round spermatids
    • doi:10.1111/j.1439-0272.2004.00617.x
    • Movahedin M, Ajeen A, Ghorbanzadeh N, Tiraihi T, Valojerdi MR, Kazemnejad A. In vitro maturation of fresh and frozen-thawed mouse round spermatids. Andrologia (2004) 36(5):269-76. doi:10.1111/j.1439-0272.2004.00617.x.
    • (2004) Andrologia , vol.36 , Issue.5 , pp. 269-276
    • Movahedin, M.1    Ajeen, A.2    Ghorbanzadeh, N.3    Tiraihi, T.4    Valojerdi, M.R.5    Kazemnejad, A.6
  • 10
    • 79953067218 scopus 로고    scopus 로고
    • In vitro production of functional sperm in cultured neonatal mouse testes
    • doi:10.1038/nature09850
    • Sato T, Katagiri K, Gohbara A, Inoue K, Ogonuki N, Ogura A, et al. In vitro production of functional sperm in cultured neonatal mouse testes. Nature (2011) 471(7339):504-7. doi:10.1038/nature09850.
    • (2011) Nature , vol.471 , Issue.7339 , pp. 504-507
    • Sato, T.1    Katagiri, K.2    Gohbara, A.3    Inoue, K.4    Ogonuki, N.5    Ogura, A.6
  • 11
    • 84885912474 scopus 로고    scopus 로고
    • Fact or fiction: in vitro spermatogenesis
    • doi:10.4161/spmg.21983
    • Reuter K, Schlatt S, Ehmcke J, Wistuba J. Fact or fiction: in vitro spermatogenesis. Spermatogenesis (2012) 2(4):245-52. doi:10.4161/spmg.21983.
    • (2012) Spermatogenesis , vol.2 , Issue.4 , pp. 245-252
    • Reuter, K.1    Schlatt, S.2    Ehmcke, J.3    Wistuba, J.4
  • 13
    • 84895910983 scopus 로고    scopus 로고
    • Reassembly of somatic cells and testicular organogenesis in vitro
    • doi:10.1016/j.tice.2013.12.001
    • Reuter K, Ehmcke J, Stukenborg JB, Simoni M, Damm OS, Redmann K, et al. Reassembly of somatic cells and testicular organogenesis in vitro. Tissue Cell (2014) 46(1):86-96. doi:10.1016/j.tice.2013.12.001.
    • (2014) Tissue Cell , vol.46 , Issue.1 , pp. 86-96
    • Reuter, K.1    Ehmcke, J.2    Stukenborg, J.B.3    Simoni, M.4    Damm, O.S.5    Redmann, K.6
  • 14
    • 58149291745 scopus 로고    scopus 로고
    • Immunomagnetic separation of normal rat testicular cells from Roser's T-cell leukaemia cells is ineffective
    • doi:10.1111/j.1365-2605.2007.00819.x
    • Hou M, Andersson M, Zheng C, Sundblad A, Soder O, Jahnukainen K. Immunomagnetic separation of normal rat testicular cells from Roser's T-cell leukaemia cells is ineffective. Int J Androl (2009) 32(1):66-73. doi:10.1111/j.1365-2605.2007.00819.x.
    • (2009) Int J Androl , vol.32 , Issue.1 , pp. 66-73
    • Hou, M.1    Andersson, M.2    Zheng, C.3    Sundblad, A.4    Soder, O.5    Jahnukainen, K.6
  • 15
    • 84861217489 scopus 로고    scopus 로고
    • Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents
    • doi:10.1371/journal.pone.0037064
    • van den Driesche S, Walker M, McKinnell C, Scott HM, Eddie SL, Mitchell RT, et al. Proposed role for COUP-TFII in regulating fetal Leydig cell steroidogenesis, perturbation of which leads to masculinization disorders in rodents. PLoS One (2012) 7(5):e37064. doi:10.1371/journal.pone.0037064.
    • (2012) PLoS One , vol.7 , Issue.5
    • van den Driesche, S.1    Walker, M.2    McKinnell, C.3    Scott, H.M.4    Eddie, S.L.5    Mitchell, R.T.6
  • 17
    • 73249122860 scopus 로고    scopus 로고
    • Extraction of high quality RNA from polysaccharide matrices using cetyltrimethylammonium bromide
    • doi:10.1016/j.biomaterials.2009.11.024
    • Wang L, Stegemann JP. Extraction of high quality RNA from polysaccharide matrices using cetyltrimethylammonium bromide. Biomaterials (2010) 31(7):1612-8. doi:10.1016/j.biomaterials.2009.11.024.
    • (2010) Biomaterials , vol.31 , Issue.7 , pp. 1612-1618
    • Wang, L.1    Stegemann, J.P.2
  • 18
    • 0028837040 scopus 로고
    • Apoptosis in testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages
    • doi:10.1210/en.136.1.5
    • Billig H, Furuta I, Rivier C, Tapanainen J, Parvinen M, Hsueh AJ. Apoptosis in testis germ cells: developmental changes in gonadotropin dependence and localization to selective tubule stages. Endocrinology (1995) 136(1):5-12. doi:10.1210/en.136.1.5.
    • (1995) Endocrinology , vol.136 , Issue.1 , pp. 5-12
    • Billig, H.1    Furuta, I.2    Rivier, C.3    Tapanainen, J.4    Parvinen, M.5    Hsueh, A.J.6
  • 19
    • 0027173161 scopus 로고
    • Hormonal control of apoptotic cell death in the testis: gonadotropins and androgens as testicular cell survival factors
    • doi:10.1210/me.7.5.643
    • Tapanainen JS, Tilly JL, Vihko KK, Hsueh AJ. Hormonal control of apoptotic cell death in the testis: gonadotropins and androgens as testicular cell survival factors. Mol Endocrinol (1993) 7(5):643-50. doi:10.1210/me.7.5.643.
    • (1993) Mol Endocrinol , vol.7 , Issue.5 , pp. 643-650
    • Tapanainen, J.S.1    Tilly, J.L.2    Vihko, K.K.3    Hsueh, A.J.4
  • 20
    • 0017200063 scopus 로고
    • Biological action of gonadotropins in the male
    • Steinberger E. Biological action of gonadotropins in the male. Pharmacol Ther B (1976) 2(4):771-86.
    • (1976) Pharmacol Ther B , vol.2 , Issue.4 , pp. 771-786
    • Steinberger, E.1
  • 21
    • 0015409865 scopus 로고
    • Adenosine 3':5'-cyclic monophosphate control of the enzymes of glutamine metabolism in Escherichia coli
    • doi:10.1073/pnas.69.10.2922
    • Prusiner S, Miller RE, Valentine RC. Adenosine 3':5'-cyclic monophosphate control of the enzymes of glutamine metabolism in Escherichia coli. Proc Natl Acad Sci U S A (1972) 69(10):2922-6. doi:10.1073/pnas.69.10.2922.
    • (1972) Proc Natl Acad Sci U S A , vol.69 , Issue.10 , pp. 2922-2926
    • Prusiner, S.1    Miller, R.E.2    Valentine, R.C.3
  • 22
    • 0015041887 scopus 로고
    • Regulation of rat liver glutamine synthetase: activation by alpha-ketoglutarate and inhibition by glycine, alanine, and carbamyl phosphate
    • doi:10.1073/pnas.68.4.781
    • Tate SS, Meister A. Regulation of rat liver glutamine synthetase: activation by alpha-ketoglutarate and inhibition by glycine, alanine, and carbamyl phosphate. Proc Natl Acad Sci U S A (1971) 68(4):781-5. doi:10.1073/pnas.68.4.781.
    • (1971) Proc Natl Acad Sci U S A , vol.68 , Issue.4 , pp. 781-785
    • Tate, S.S.1    Meister, A.2
  • 23
    • 0021273929 scopus 로고
    • The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation
    • doi:10.1002/jcp.1041200218
    • Engstrom W, Zetterberg A. The relationship between purines, pyrimidines, nucleosides, and glutamine for fibroblast cell proliferation. J Cell Physiol (1984) 120(2):233-41. doi:10.1002/jcp.1041200218.
    • (1984) J Cell Physiol , vol.120 , Issue.2 , pp. 233-241
    • Engstrom, W.1    Zetterberg, A.2
  • 24
    • 0029783888 scopus 로고    scopus 로고
    • Glutamine as a regulator of DNA and protein biosynthesis in human solid tumor cell lines
    • doi:10.1097/00000658-199608000-00012
    • Wasa M, Bode BP, Abcouwer SF, Collins CL, Tanabe KK, Souba WW. Glutamine as a regulator of DNA and protein biosynthesis in human solid tumor cell lines. Ann Surg (1996) 224(2):189-97. doi:10.1097/00000658-199608000-00012.
    • (1996) Ann Surg , vol.224 , Issue.2 , pp. 189-197
    • Wasa, M.1    Bode, B.P.2    Abcouwer, S.F.3    Collins, C.L.4    Tanabe, K.K.5    Souba, W.W.6
  • 25
    • 0028104418 scopus 로고
    • The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR).
    • Clark BJ, Wells J, King SR, Stocco DM. The purification, cloning, and expression of a novel luteinizing hormone-induced mitochondrial protein in MA-10 mouse Leydig tumor cells. Characterization of the steroidogenic acute regulatory protein (StAR). J Biol Chem (1994) 269(45):28314-22.
    • (1994) J Biol Chem , vol.269 , Issue.45 , pp. 28314-28322
    • Clark, B.J.1    Wells, J.2    King, S.R.3    Stocco, D.M.4
  • 26
    • 0033743755 scopus 로고    scopus 로고
    • Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice
    • doi:10.1210/mend.14.9.0515
    • Hasegawa T, Zhao L, Caron KM, Majdic G, Suzuki T, Shizawa S, et al. Developmental roles of the steroidogenic acute regulatory protein (StAR) as revealed by StAR knockout mice. Mol Endocrinol (2000) 14(9):1462-71. doi:10.1210/mend.14.9.0515.
    • (2000) Mol Endocrinol , vol.14 , Issue.9 , pp. 1462-1471
    • Hasegawa, T.1    Zhao, L.2    Caron, K.M.3    Majdic, G.4    Suzuki, T.5    Shizawa, S.6
  • 27
    • 0035970108 scopus 로고    scopus 로고
    • Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide
    • doi:10.1073/pnas.98.3.1267
    • Li H, Yao Z, Degenhardt B, Teper G, Papadopoulos V. Cholesterol binding at the cholesterol recognition/interaction amino acid consensus (CRAC) of the peripheral-type benzodiazepine receptor and inhibition of steroidogenesis by an HIV TAT-CRAC peptide. Proc Natl Acad Sci U S A (2001) 98(3):1267-72. doi:10.1073/pnas.98.3.1267.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.3 , pp. 1267-1272
    • Li, H.1    Yao, Z.2    Degenhardt, B.3    Teper, G.4    Papadopoulos, V.5
  • 28
    • 0031755752 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor function in cholesterol transport Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern.
    • doi:10.1210/endo.139.12.6390
    • Li H, Papadopoulos V. Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern. Endocrinology (1998) 139(12):4991-7. doi:10.1210/endo.139.12.6390.
    • (1998) Endocrinology , vol.139 , Issue.12 , pp. 4991-4997
    • Li, H.1    Papadopoulos, V.2
  • 29
    • 0036080919 scopus 로고    scopus 로고
    • Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma
    • doi:10.1016/S0002-9440(10)61157-1
    • Wistuba II, Ashfaq R, Maitra A, Alvarez H, Riquelme E, Gazdar AF. Fragile histidine triad gene abnormalities in the pathogenesis of gallbladder carcinoma. Am J Pathol (2002) 160(6):2073-9. doi:10.1016/S0002-9440(10)61157-1.
    • (2002) Am J Pathol , vol.160 , Issue.6 , pp. 2073-2079
    • Wistuba, I.I.1    Ashfaq, R.2    Maitra, A.3    Alvarez, H.4    Riquelme, E.5    Gazdar, A.F.6
  • 30
    • 0026557912 scopus 로고
    • Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes
    • Ruppert S, Cole TJ, Boshart M, Schmid E, Schutz G. Multiple mRNA isoforms of the transcription activator protein CREB: generation by alternative splicing and specific expression in primary spermatocytes. EMBO J (1992) 11(4):1503-12.
    • (1992) EMBO J , vol.11 , Issue.4 , pp. 1503-1512
    • Ruppert, S.1    Cole, T.J.2    Boshart, M.3    Schmid, E.4    Schutz, G.5
  • 32
    • 0029941935 scopus 로고    scopus 로고
    • Role of transcription factors CREB and CREM in cAMP-regulated transcription during spermatogenesis
    • doi:10.1016/1043-2760(96)00035-5
    • Walker WH, Habener JF. Role of transcription factors CREB and CREM in cAMP-regulated transcription during spermatogenesis. Trends Endocrinol Metab (1996) 7(4):133-8. doi:10.1016/1043-2760(96)00035-5.
    • (1996) Trends Endocrinol Metab , vol.7 , Issue.4 , pp. 133-138
    • Walker, W.H.1    Habener, J.F.2
  • 33
    • 0033279522 scopus 로고    scopus 로고
    • Germ cell-specific cyclic adenosine 3',5'-monophosphate response element modulator expression in rodent and primate testis is maintained despite gonadotropin deficiency
    • doi:10.1210/endo.140.6.6764
    • Behr R, Weinbauer GF. Germ cell-specific cyclic adenosine 3',5'-monophosphate response element modulator expression in rodent and primate testis is maintained despite gonadotropin deficiency. Endocrinology (1999) 140(6):2746-54. doi:10.1210/endo.140.6.6764.
    • (1999) Endocrinology , vol.140 , Issue.6 , pp. 2746-2754
    • Behr, R.1    Weinbauer, G.F.2
  • 34
    • 0032127981 scopus 로고    scopus 로고
    • Molecular mechanisms of male germ cell differentiation
    • doi:10.1002/(SICI)1521-1878(199807)20:7<555::AID-BIES6>3.3.CO;2-J
    • Hecht NB. Molecular mechanisms of male germ cell differentiation. Bioessays (1998) 20(7):555-61. doi:10.1002/(SICI)1521-1878(199807)20:7<555::AID-BIES6>3.3.CO;2-J.
    • (1998) Bioessays , vol.20 , Issue.7 , pp. 555-561
    • Hecht, N.B.1
  • 35
    • 33746416626 scopus 로고    scopus 로고
    • De novo morphogenesis of seminiferous tubules from dissociated immature rat testicular cells in xenografts
    • doi:10.2164/jandrol.05207
    • Gassei K, Schlatt S, Ehmcke J. De novo morphogenesis of seminiferous tubules from dissociated immature rat testicular cells in xenografts. J Androl (2006) 27:611-8. doi:10.2164/jandrol.05207.
    • (2006) J Androl , vol.27 , pp. 611-618
    • Gassei, K.1    Schlatt, S.2    Ehmcke, J.3
  • 36
    • 84875550330 scopus 로고    scopus 로고
    • Effects of nanostructures and mouse embryonic stem cells on in vitro morphogenesis of rat testicular cords
    • doi:10.1371/journal.pone.0060054
    • Pan F, Chi L, Schlatt S. Effects of nanostructures and mouse embryonic stem cells on in vitro morphogenesis of rat testicular cords. PLoS One (2013) 8(3):e60054. doi:10.1371/journal.pone.0060054.
    • (2013) PLoS One , vol.8 , Issue.3
    • Pan, F.1    Chi, L.2    Schlatt, S.3
  • 37
    • 29244454259 scopus 로고    scopus 로고
    • Spermatogonia: origin, physiology and prospects for conservation and manipulation of the male germ line
    • doi:10.1071/RD05119
    • Ehmcke J, Hubner K, Scholer HR, Schlatt S. Spermatogonia: origin, physiology and prospects for conservation and manipulation of the male germ line. Reprod Fertil Dev (2006) 18(1-2):7-12. doi:10.1071/RD05119.
    • (2006) Reprod Fertil Dev , vol.18 , Issue.1-2 , pp. 7-12
    • Ehmcke, J.1    Hubner, K.2    Scholer, H.R.3    Schlatt, S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.