Honokiol suppresses TNF-α-induced migration and matrix metalloproteinase expression by blocking NF-κB activation via the ERK signaling pathway in rat aortic smooth muscle cells

Acta Histochemica

Volumn 116, Issue 4, 2014, Pages 588-595

  Zhu, Xiaoying ^a,b   Wang, Zhansheng ^a   Hu, Cuizhu ^a   Li, Zhao ^a   Hu, Jian ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

^b Benxi Beiying Iron and Steel Group Co Ltd   (China)

Author keywords

ERK; Honokiol; Matrix metalloproteinase 2 9; Migration; Nuclear factor B; Vascular smooth muscle cells

Indexed keywords

GELATINASE A; GELATINASE B; HONOKIOL; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MATRIX METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; BIPHENYL DERIVATIVE; LIGNAN;

ANIMAL CELL; ANTIPROLIFERATIVE ACTIVITY; AORTA MEDIA; ARTICLE; ATHEROSCLEROSIS; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; INTRACELLULAR SIGNALING; MAGNOLIA OFFICINALIS; MALE; MIGRATION INHIBITION; NONHUMAN; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; SMOOTH MUSCLE FIBER; ANIMAL; AORTA; CYTOLOGY; DRUG EFFECTS; METABOLISM; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; VASCULAR SMOOTH MUSCLE;

ANIMALS; AORTA; BIPHENYL COMPOUNDS; LIGNANS; MALE; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MUSCLE, SMOOTH, VASCULAR; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84901014302     PISSN: 00651281     EISSN: 16180372     Source Type: Journal    
DOI: 10.1016/j.acthis.2013.11.005     Document Type: Article

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