Formation of hydroxyl radicals contributes to the bactericidal activity of ciprofloxacin against Pseudomonas aeruginosa biofilms

Pathogens and Disease

Volumn 70, Issue 3, 2014, Pages 440-443

  Jensen, Peter Ø ^a   Briales, Alejandra ^a,b   Brochmann, Rikke P ^a   Wang, Hengzhuang ^a   Kragh, Kasper N ^c   Kolpen, Mette ^a   Hempel, Casper ^a   Bjarnsholt, Thomas ^a,c   Høiby, Niels ^a,c   Ciofu, Oana ^c  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF SEVILLE   (Spain)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Biofilm; Ciprofloxacin; Cystic fibrosis; Oxidative stress; Pseudomonas aeruginosa

Indexed keywords

CIPROFLOXACIN; HYDROXYL RADICAL; REACTIVE OXYGEN METABOLITE; THIOUREA; ANTIINFECTIVE AGENT;

ANTIBIOTIC THERAPY; ARTICLE; BACTERIAL GENE; BACTERIAL VIABILITY; BACTERICIDAL ACTIVITY; BIOFILM; CONTROLLED STUDY; DRUG EFFECT; GYRA GENE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; WILD TYPE; COMPLICATION; CYSTIC FIBROSIS; DRUG EFFECTS; GROWTH, DEVELOPMENT AND AGING; HUMAN; METABOLISM; MICROBIOLOGY; PHYSIOLOGY; PSEUDOMONAS INFECTION;

ANTI-BACTERIAL AGENTS; BIOFILMS; CIPROFLOXACIN; CYSTIC FIBROSIS; HUMANS; HYDROXYL RADICAL; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS;

EID: 84901006669     PISSN: None     EISSN: 2049632X     Source Type: Journal    
DOI: 10.1111/2049-632X.12120     Document Type: Article

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