Simultaneous determination of diclofenac, its human metabolites and microbial nitration/nitrosation transformation products in wastewaters by liquid chromatography/quadrupole-linear ion trap mass spectrometry

Journal of Chromatography A

Volumn 1347, Issue , 2014, Pages 63-71

  Osorio, Victoria ^a   Imbert Bouchard, Marta ^a   Zonja, Bozo ^a   Abad, José Luis ^b   Pérez, Sandra ^a   Barceló, Damià ^a,c  

^a INSTITUTE OF ENVIRONMENTAL ASSESSMENT AND WATER RESEARCH   (Spain)

^b INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^c CATALAN INSTITUTE FOR WATER RESEARCH ICRA   (Spain)

Author keywords

Diclofenac; High resolution mass spectrometry; LC MS; Nitration; Nitrosation; Transformation products

Indexed keywords

BIOMOLECULES; DRUG PRODUCTS; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; NITRATION; WASTEWATER TREATMENT;

DICLOFENAC; HIGH RESOLUTION MASS SPECTROMETRY; LC-MS; NITROSATION; TRANSFORMATION PRODUCTS;

EFFLUENTS;

4' HYDROXYDICLOFENAC; 4',5 DIHYDROXYDICLOFENAC; 5 HYDROXYDICLOFENAC; ACYL GLUCURONIDE; DICLOFENAC; DRUG METABOLITE; NITRO DERIVATIVE; NITROSO DERIVATIVE; TP323; TP339; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG DETERMINATION; ION TRAP MASS SPECTROMETRY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; NITRATION; NITROSATION; PRIORITY JOURNAL; PROCESS DEVELOPMENT; PROCESS OPTIMIZATION; QUANTITATIVE ANALYSIS; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; WASTE WATER; WATER SAMPLING;

DICLOFENAC; HIGH RESOLUTION MASS SPECTROMETRY; LC-MS; NITRATION; NITROSATION; TRANSFORMATION PRODUCTS;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, LIQUID; DICLOFENAC; HUMANS; NITROSATION; REFERENCE STANDARDS; SOLID PHASE EXTRACTION; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; WASTE WATER; WATER POLLUTANTS, CHEMICAL;

EID: 84900990337     PISSN: 00219673     EISSN: 18733778     Source Type: Journal    
DOI: 10.1016/j.chroma.2014.04.058     Document Type: Article

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