Aquaporins in the central nervous system

Handbook of Neurochemistry and Molecular Neurobiology: Neural Membranes and Transport

Volumn , Issue , 2007, Pages 171-190

  Papadopoulos, M C ^a,b   Saadoun, S ^a,b   Verkman, A S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ST GEORGE S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84900924386     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-0-387-30380-2_8     Document Type: Chapter

References (111)

1. Agre P, Kozono D. 2003. Aquaporin water channels: Molecular mechanisms for human diseases. FEBS Lett 555:72-78.
2. Amiry-Moghaddam M, Otsuka T, Hurn PD, Traystman RJ, Haug FM, et al. 2003. An alpha-syntrophin-dependent pool of AQP4 in astroglial end-feet confers bidirectional water flow between blood and brain. Proc Natl Acad Sci USA 100:2106-2111.
3. Aoki K, Uchihara T, Tsuchiya K, Nakamura A, Ikeda K, et al. 2003. Enhanced expression of aquaporin 4 in human brain with infarction. Acta Neuropathol (Berl) 106:121-124.
4. Arima H, Yamamoto N, Sobue K, Umenishi F, Tada T, et al. 2003. Hyperosmolar mannitol simulates expression of aqua-porins 4 and 9 through a p38 mitogen-activated protein kinase-dependent pathway in rat astrocytes. J Biol Chem 278:44525-44534.
5. Badaut J, Regli L. 2004. Distribution and possible roles of aquaporin 9 in the brain. Neuroscience 129:971-981.
6. Badaut J, Hirt L, Granziera C, Bogousslavsky J, Magistretti PJ, et al. 2001. Astrocyte-specific expression of aquaporin-9 in mouse brain is increased after transient focal cerebral ischemia. J Cereb Blood Flow Metab 21:477-482.
7. Badaut J, Lasbennes F, Magistretti PJ, Regli L. 2002. Aquapor-ins in brain: Distribution, physiology, and pathophysiolo-gy. J Cereb Blood Flow Metab 22:367-378.
8. Binder DK, Papadopoulos MC, Haggie PM, Verkman AS. 2004a. In vivo measurement of brain extracellular spacediffusion by cortical surface photobleaching. J Neurosci 24:8049-8056.
9. Binder DK, Oshio K, Ma T, Verkman AS, Manley GT. 2004b. Increased seizure threshold in mice lacking aquaporin-4 water channels. Neuroreport 15:259-262.
10. Binder DK, Yao X, Sick TJ, Verkman AS, Manley GT. 2006. Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia. 53:631-636.
11. Bloch O, Papadopoulos MC, Manley GT, Verkman AS. 2005. Aquaporin-4 gene deletion in mice increases focal edema associated with staphylococcal brain abscess. J Neurochem 95:254-262.
12. Bloch O, Manley GT, Verkman AS. 2006. Accelerated progression of kaolin-induced hydrocephalus in aquaporin-4 deficient mice. J Cereb Blood Flow Metab, in press.
13. Brown PD, Davies SL, Speake T, Millar ID. 2004. Molecular mechanisms of cerebrospinal fluid production. Neuroscience 129:957-970.
14. Bush TG, Puvanachandra N, Horner CH, Polito A, Ostenfeld T, et al. 1999. Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice. Neuron 23:297-308.
15. Carbrey JM, Gorelick-Feldman DA, Kozono D, Praetorius J, Nielsen S, et al. 2003. Aquaglyceroporin AQP9: Solute permeation and metabolic control of expression in liver. Proc Natl Acad Sci USA 100:2945-2950.
16. Condeelis J. 1993. Life at the leading edge: The formation of cell protrusions. Annu Rev Cell Biol 9:411-444.
17. de Groot BL, Engel A, Grubmuller H. 2003. The structure of the aquaporin-1 water channel: A comparison between cryo-electron microscopy and X-ray crystallography. J Mol Biol 325:485-493.
18. Dolman D, Drndarski S, Abbott NJ, Rattray M. 2005. Induction of aquaporin 1 but not aquaporin 4 messenger RNA in rat primary brain microvessel endothelial cells in culture. J Neurochem 93:825-833.
19. Elkjaer M, Vajda Z, Nejsum LN, Kwon T, Jensen UB, et al. 2000. Immunoloalization of AQP9 in liver, epididymis, testis, spleen, and brain. Biochem Biophys Res Commun 276:1118-1128.
20. Kwon T, Endo M, Jain RK, Witwer B, Brown D. 1999. Water channel (aquaporin 1) expression and distribution in mammary carcinomas and glioblastomas. Microvasc Res 58:89-98.
21. Engel A, Stahlberg H. 2002. Aquaglyceroporins: Channel proteins with a conserved core, multiple functions, and variable surfaces. Int Rev Cytol 215:75-104.
22. Ennis SR, Keep RF. 2006. The effects of cerebral ischemia on the rat choroid plexus. J Cereb Blood Flow Metab 26:675-683.
23. Fishman RA. 1975. Brain edema. N Engl J Med 293:706-711.
24. Frigeri A, Gropper MA, Umenishi F, Kawashima M, Brown D, et al. 1995. Localization of MIWC and GLIP water channel homologs in neuromuscular, epithelial and glandular tissues. J Cell Sci 108:2993-3002.
25. Fujiyoshi Y, Mitsuoka K, de Groot BL, Philippsen A, Grubmuller H, et al. 2002. Structure and function of water channels. Curr Opin Struct Biol 12:509-515.
26. Furman CS, Gorelick-Feldman DA, Davidson KG, Yasumura T, Neely JD, et al. 2003. Aquaporin-4 square array assembly: Opposing actions of M1 and M23 isoforms. Proc Natl Acad Sci USA 100:13609-13614.
27. Hara M, Verkman AS. 2003. Glycerol replacement corrects defective skin hydration, elasticity, and barrier function in aquaporin-3-deficient mice. Proc Natl Acad Sci USA 100:7360-7365.
28. Hara-Chikuma M, Verkman AS. 2006. Aquaporin-1 facilitates epithelial cell migration in kidney proximal tubule. J Am Soc Nephrol 17:39-45.
29. Hara-Chikuma M, Sohara E, Rai T, Ikawa M, Okabe M, et al. 2005. Progressive adipocyte hypertrophy in aquaporin-7-deficient mice: Adipocyte glycerol permeability as a novel regulatoroffat accumulation. J Biol Chem 280:15493-15496.
30. Harries WE, Akhavan D, Miercke LJ, Khademi S, Stroud RM. 2004. The channel architecture of aquaporin 0 at a 2. 2-A resolution. Proc Natl Acad Sci USA 101:14045-14050.
31. Hasegawa H, Zhang R, Dohrman A, Verkman AS. 1993. Tissue-specific expression of mRNA encoding rat kidney water channel CHIP28k by in situ hybridization. Am J Physiol 264:C237-C245.
32. Ishibashi K, Kuwahara M, Gu Y, Tanaka Y, Jung JS, Bhat RV, Preston GM, Guggino WB, Baraban JM, et al. 1994. Molecular characterization of an aquaporin cDNA from brain: Candidate osmoreceptor and regulator of water balance. Proc Natl Acad Sci USA 91:13052-13056.
33. Ke C, Poon WS, Ng HK, Pang JC, Chan Y. 2001. Heterogeneous responses of aquaporin-4 in oedema formation in a replicated severe traumatic brain injury model in rats. Neurosci Lett 301:21-24.
34. Ke C, Poon WS, Ng HK, Lai FM, Tang NL, et al. 2002. Impact of experimental acute hyponatremia on severe traumatic brain injury in rats: Influences on injuries, permeability of blood-brain barrier, ultrastructural features, and aquaporin-4 expression. Exp Neurol 178:194-206.
35. Keep RF, Xiang J, Ulanski LJ, Brosius FC, Betz AL. 1997. Choroid plexus ion transporter expression and cere-brospinal fluid secretion. Acta Neurochir Suppl 70:279-281.
36. Kiening KL, van Landeghem FK, Schreiber S, Thomale UW, von Deimling A, et al. 2002. Decreased hemispheric Aqua-porin-4 is linked to evolving brain edema following controlled cortical impact injury in rats. Neurosci Lett 324:105-108.
37. Kimelberg HK. 1995. Current conceptsof brain edema. Review of laboratory investigations. J Neurosurg 83:1051-1059.
38. Klatzo I. 1987. Pathophysiological aspects of brain edema. Acta Neuropathol (Berl) 72:236-239.
39. Ko SB, Uchida S, Naruse S, Kuwahara M, Ishibashi K, et al. 1999. Cloning and functional expression of rAOP9L a new member of aquaporin family from rat liver. Biochem Mol Biol Int 47:309-318.
40. Lambrechts A, Van Troys M, Ampe C. 2004. The actin cyto-skeleton in normal and pathological cell motility. Int J Biochem Cell Biol 36:1890-1909.
41. Lauffenburger DA, Horwitz AF. 1996. Cell migration: A physically integrated molecular process. Cell 84:359-369.
42. Lee TS, Eid T, Mane S, Kim JH, Spencer DD, et al. 2004. Aquaporin-4 is increased in the sclerotic hippocampus in human temporal lobe epilepsy. Acta Neuropathol (Berl) 108:493-502.
43. Lehmenkuhler A, Sykova E, Svoboda J, Zilles K, Nicholson C. 1993. Extracellular space parameters in the rat neocortex and subcortical white matter during postnatal development determined by diffusion analysis. Neuroscience 55:339-351.
44. Li J, Verkman AS. 2001. Impaired hearing in mice lacking aquaporin-4 water channels. J Biol Chem 276:31233-31237.
45. Li J, Patil RV, Verkman AS. 2002. Mildly abnormal retinal function in transgenic mice without Muller cell aquaporin-4 water channels. Invest Ophthalmol Vis Sci 43:573-579.
46. Longatti PL, Basaldella L, Orvieto E, Fiorindi A, Carteri A. 2004. Choroid plexus and aquaporin-1: A novel explanation of cerebrospinal fluid production. Pediatr Neurosurg 40:277-283.
47. Lu M, Lee MD, Smith BL, Jung JS, Agre P, et al. 1996. The human AQP4 gene: Definition of the locus encoding two water channel polypeptides in brain. Proc Natl Acad Sci USA 93:10908-10912.
48. Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, et al. 1997. Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. J Clin Invest 100:957-962.
49. Manley GT, Fujimura M, Ma T, Noshita N, Filiz F, et al. 2000. Aquaporin-4 deletion in mice reduces brain edema after acute water intoxication and ischemic stroke. Nat Med 6:159-163.
50. Manley GT, Binder DK, Papadopoulos MC, Verkman AS. 2004. New insights into water transport and edema in the central nervous system from phenotype analysis of aquaporin-4 null mice. Neuroscience 129:983-991.
51. Masseguin C, Corcoran M, Carcenac C, Daunton NG, Guell A, et al. 2000. Altered gravity downregulates aquaporin-1 protein expression in choroid plexus. J Appl Physiol 88:843-850.
52. Matsumoto I, Nagamatsu N, Arai S, Emori Y, Abe K. 2004. Identification of candidate genes involved in somatosenso-ry functions of cranial sensory ganglia. Brain Res Mol Brain Res 126:98-102.
53. Mobasheri A, Marples D. 2004. Expression of the AQP-1 water channel in normal human tissues: A semiquantitative study using tissue microarray technology. Am J Physiol Cell Physiol 286:C529-C537.
54. Murata K, Mitsuoka K, Hirai T, Walz T, Agre P, et al. 2000. Structural determinants of water permeation through aquaporin-1. Nature 407:599-605.
55. Nicchia GP, Frigeri A, Nico B, Ribatti D, Svelto M. 2001. Tissue distribution and membrane localization of aqua-porin-9 water channel: Evidence for sex-linked differences in liver. J Histochem Cytochem 49:1547-1556.
56. Nico B, Frigeri A, Nicchia GP, Corsi P, Ribatti D, et al. 2003. Severe alterations of endothelial and glial cells in the blood-brain barrier of dystrophic mdx mice. Glia 42:235-251.
57. Nielsen S, Nagelhus EA, Amiry-Moghaddam M, Bourque C, Agre P, et al. 1997. Specialized membrane domains for water transport in glial cells: High-resolution immunogold cytochemistry of aquaporin-4 in rat brain. J Neurosci 17:171-180.
58. Oshio K, Binder DK, Yang B, Schecter S, Verkman AS, et al. 2004. Expression of aquaporin water channels in mouse spinal cord. Neuroscience 127:685-693.
59. Oshio K, Watanabe H, Song Y, Verkman AS, Manley GT. 2005. Reduced cerebrospinal fluid production and intracranial pressure in mice lacking choroid plexus water channel Aquaporin-1. FASEB J 19:76-78.
60. Oshio K, Watanabe H, Yan D, Verkman AS, Manley GT. 2006. Impaired pain sensation in mice lacking aquaporin-1 water channels. Biochem Biophys Res Commun, 341:1022-1028.
61. Padmawar P, Yao X, Bloch O, Manley GT, Verkman AS. 2005. K+ waves in brain cortex visualized using a long-wavelength K+-sensing fluorescent indicator. Nat Methods 2:825-827.
62. Papadopoulos MC, Verkman AS. 2005. Aquaporin-4 gene disruption in mice reduces brain swelling and mortality in pneumococcal meningitis. J Biol Chem 280:13906-13912.
63. Papadopoulos MC, Krishna S, Verkman AS. 2002. Aquaporin water channels and brain edema. Mt Sinai J Med 69:242-248.
64. Papadopoulos MC, Manley GT, Krishna S, Verkman AS. 2004a. Aquaporin-4 facilitates reabsorption of excess fluid in vasogenic brain edema. FASEB J 18:1291-1293.
65. Papadopoulos MC, Saadoun S, Binder DK, Manley GT, Krishna S, et al. 2004b. Molecular mechanisms of brain tumor edema. Neuroscience 129:1011-1020.
66. Papadopoulos MC, Binder DK, Verkman AS. 2005. Enhanced macromolecular diffusion in brain extracellular space in mouse models of vasogenic edema measured by cortical surface photobleaching. FASEB J 19:425-427.
67. Pekny M, Nilsson M. 2005. Astrocyte activation and reactive gliosis. Glia 50:427-434.
68. Puwarawuttipanit W, Bragg AD, Frydenlund DS, Mylonakou MN, Nagelhus EA, et al. 2006. Differential effect of alpha-syntrophin knockout on aquaporin-4 and Kir4. 1 expression in retinal macroglial cells in mice. Neuroscience 137:165-175.
69. Rash JE, Yasumura T, Hudson CS, Agre P, Nielsen S. 1998. Direct immunogold labeling of aquaporin-4 in square arrays of astrocyte and ependymocyte plasma membranes in rat brain and spinal cord. Proc Natl Acad Sci USA 95:11981-11986.
70. Redzic ZB, Segal MB. 2004. The structure of the choroid plexus and the physiology of the choroid plexus epithelium. Adv Drug Deliv Rev 56:1695-1716.
71. Ren G, Cheng A, Reddy V, Melnyk P, Mitra AK. 2000. Three-dimensional fold of the human AQP1 water channel determined at 4 A resolution by electron crystallography of two-dimensional crystals embedded in ice. J Mol Biol 301:369-387.
72. Ren G, Reddy VS, Cheng A, Melnyk P, Mitra AK. 2001. Visualization of a water-selective pore by electron crystallography in vitreous ice. Proc Natl Acad Sci USA 98:1398-1403.
73. Reulen HJ, Tsuyumu M, Tack A, Fenske AR, Prioleau GR. 1978. Clearance of edema fluid into cerebrospinal fluid. A mechanism for resolution of vasogenic brain edema. J Neurosurg 48:754-764.
74. Reulen HJ, Tsuyumu M, Prioleau G. 1980. Further results concerning the resolution of vasogenic brain edema. Adv Neurol 28:375-381.
75. Ringler P, Borgnia MJ, Stahlberg H, Maloney PC, Agre P, et al. 1999. Structure of the water channel AqpZ from Escher-ichia coli revealed by electron crystallography. J Mol Biol 291:1181-1190.
76. Saadoun S, Papadopoulos MC, Davies DC, Bell BA, Krishna S. 2002a. Increased aquaporin 1 water channel expression in human brain tumors. Br J Cancer 87:621-623.
77. Saadoun S, Papadopoulos MC, Davies DC, Krishna S, Bell BA. 2002b. Aquaporin-4 expression is increased in oedematous human brain tumors. J Neurol Neurosurg Psychiatry 72:262-265.
78. + siphoning in brain contusion, bacterial meningitis, and brain tumors: Immu-nohistochemical case review. J Clin Pathol 56:972-975.
79. Saadoun S, Papadopoulos MC, Hara-Chikuma M, Verkman AS. 2005. Impairment of angiogenesis and cell migration by targeted aquaporin-1 gene disruption. Nature 434:786-792.
80. Schenk AD, Werten PJ, Scheuring S, de Groot BL, Muller SA, et al. 2005. The 4. 5 A structure of human AQP2. J Mol Biol 350:278-289.
81. Silberstein C, Bouley R, Huang Y, Fang P, Pastor-Soler N, et al. 2004. Membrane organization and function of M1 and M23 isoforms of aquaporin-4 in epithelial cells. Am J Physiol Renal Physiol 287:F501-F511.
82. Silver J, Miller JH. 2004. Regeneration beyond the glial scar. Nat Rev Neurosci 5:146-156.
83. Solenov EI, Vetrivel L, Oshio K, Manley GT, Verkman AS. 2002. Optical measurement of swelling and water transport in spinal cord slices from aquaporin null mice. J Neurosci Methods 113:85-90.
84. Speake T, Freeman LJ, Brown PD. 2003. Expression of aqua-porin 1 and aquaporin 4 water channels in rat choroid plexus. Biochim Biophys Acta 1609:80-86.
85. Sui H, Walian PJ, Tang G, Oh A, Jap BK. 2000. Crystallization and preliminary X-ray crystallographic analysis of water channel AQP1. Acta Crystallogr D Biol Crystallogr 56:1198-1200.
86. Sui H, Han BG, Lee JK, Walian P, Jap BK. 2001. Structural basis of water-specific transport through the AQP1 water channel. Nature 414:872-878.
87. Sun MC, Honey CR, Berk C, Wong NL, Tsui JK. 2003. Regulation of aquaporin-4 in a traumatic brain injury model in rats. J Neurosurg 98:565-569.
88. Tajkhorshid E, Nollert P, Jensen MO, Miercke LJ, O'Connell J, et al. 2002. Control of the selectivity of the aquaporin water channel family by global orientational tuning. Science 296:525-530.
89. Taniguchi M, Yamashita T, Kumura E, Tamatani M, Kobayashi A, et al. 2000. Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat. Brain Res Mol Brain Res 78:131-137.
90. Tomas-Camardiel M, Venero JL, de Pablos RM, Rite I, Machado A, et al. 2004. In vivo expression of aquaporin-4 by reactive microglia. J Neurochem 91:891-899.
91. Tsacopoulos M, Magistretti PJ. 1996. Metabolic coupling between glia and neurons. J Neurosci 16:877-885.
92. Tsuyumu M, Reulen HJ, Prioleau G. 1981. Dynamics of formation and resolution of vasogenic brain oedema. I. Measurement of oedema clearance into ventricular CSF. Acta Neurochir (Wien) 57:1-13.
93. Uhl E, Wrba E, Nehring V, Chang RC, Baethmann A, et al. 1999. Technical note: A new model for quantitative analysis of brain oedema resolution into the ventricles and the subarachnoid space. Acta Neurochir (Wien) 141:89-92.
94. Umenishi F, Verkman AS. 1998. Isolation and functional analysis of alternative promoters in the human aqua-porin-4 water channel gene. Genomics 50:373-377.
95. Vajda Z, Promeneur D, Doczi T, Sulyok E, Frokiaer J, et al. 2000. Increased aquaporin-4 immunoreactivity in rat brain in response to systemic hyponatremia. Biochem Biophys Res Commun 270:495-503.
96. Vajda Z, Pedersen M, Fuchtbauer EM, Wertz K, Stodkilde-Jorgensen H, et al. 2002. Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null trans-genic mice. Proc Natl Acad Sci USA 99:13131-13136.
97. Verbavatz JM, Ma T, Gobin R, Verkman AS. 1997. Absence of orthogonal arrays in kidney, brain and muscle from trans-genic knockout mice lacking water channel aquaporin-4. J Cell Sci 110:2855-2860.
98. Verkman AS. 2002. Aquaporin water channels and endothelial cell function. J Anat 200:617-627.
99. Verkman AS. 2005. Novel roles of aquaporins revealed by phenotype analysis of knockout mice. Rev Physiol Biochem Pharmacol 155:31-55.
100. Verkman AS, Mitra AK. 2000. Structure and function of aquaporin water channels. Am J Physiol Renal Physiol 278:F13-F28.
101. Vitellaro-Zuccarello L, Mazzetti S, Bosisio P, Monti C, De Biasi S. 2005. Distribution of Aquaporin 4 in rodent spinal cord: Relationship with astrocyte markers and chon-droitin sulfate proteoglycans. Glia 51:148-159.
102. Weed LH, McKibben PS. 1919. Experimental alteration of brain bulk. Am J Physiol 48:531-538.
103. Wen H, Nagelhus EA, Amiry-Moghaddam M, Agre P, Ottersen OP, et al. 1999. Ontogeny of water transport in rat brain: Postnatal expression of the aquaporin-4 water channel. Eur J Neurosci 11:935-945.
104. Wrba E, Nehring V, Chang RC, Baethmann A, Reulen HJ, et al. 1997. Quantitative analysis of brain edema resolution into the cerebral ventricles and subarachnoid space. Acta Neurochir Suppl 70:288-290.
105. Wrba E, Nehring V, Baethmann A, Reulen HJ, Uhl E. 1998. Resolution of experimental vasogenic brain edema at different intracranial pressures. Acta Neurochir Suppl 71:313-315.
106. Yamamoto N, Sobue K, Miyachi T, Inagaki M, Miura Y, et al. 2001. Differential regulation of aquaporin expression in astrocytes by protein kinase C. Brain Res Mol Brain Res 95:110-116.
107. Yamamoto N, Sobue K, Fujita M, Katsuya H, Asai K. 2002. Differential regulation of aquaporin-5 and -9 expression in astrocytes by protein kinase A. Brain Res Mol Brain Res 104:96-102.
108. Yang B, Ma T, Verkman AS. 1995. cDNA cloning, gene organization, and chromosomal localization of a human mercurial insensitive water channel. Evidence for distinct transcriptional units. J Biol Chem 270:22907-22913.
109. Yang B, Brown D, Verkman AS. 1996. The mercurial insensitive water channel (AQP-4) forms orthogonal arrays in stably transfected Chinese hamster ovary cells. J Biol Chem 271:4577-4580.
110. Yang B, van Hoek AN, Verkman AS. 1997. Very high single channel water permeability of aquaporin-4 in baculovirus-infected insect cells and liposomes reconstituted with purified aquaporin-4. Biochemistry 36:7625-7632.
111. Zampighi GA, Kreman M, Lanzavecchia S, Turk E, Eskandari S, et al. 2003. Structure of functional single AQP0 channels in phospholipid membranes. J Mol Biol 325:201-210.