Plasma polychlorinated biphenyl and organochlorine pesticide concentrations in dementia: The Canadian study of health and aging

Environment International

Volumn 69, Issue , 2014, Pages 141-147

  Medehouenou, Thierry Comlan Marc ^a,b   Ayotte, Pierre ^a,b,c   Carmichael, Pierre Hugues ^b   Kröger, Edeltraut ^a,b   Verreault, René ^a,b   Lindsay, Joan ^a,d   Dewailly, Éric ^a,b,c   Tyas, Suzanne L ^e   Bureau, Alexandre ^a,f   Laurin, Danielle ^a,b  

^a UNIVERSITÉ LAVAL   (Canada)

^b Université Laval   (Canada)

^c INSTITUT NATIONAL DE SANTÉ PUBLIQUE DU QUÉBEC   (Canada)

^d UNIVERSITY OF OTTAWA   (Canada)

^e UNIVERSITY OF WATERLOO   (Canada)

^f CENTRE DE RECHERCHE DE L INSTITUT UNIVERSITAIRE EN SANTÉ MENTALE DE QUÉBEC   (Canada)

Author keywords

Alzheimer disease; Dementia; Exposure; Organochlorine pesticide; Polychlorinated biphenyl

Indexed keywords

ALUMINUM COMPOUNDS; BLOOD; FUNGICIDES; GENES; LOGISTIC REGRESSION; METABOLITES; ORGANIC POLLUTANTS; POLYCHLORINATED BIPHENYLS; POPULATION STATISTICS;

ALZHEIMER DISEASE; CROSS-SECTIONAL DESIGN; DEMENTIA; ELEVATED CONCENTRATIONS; EXPOSURE; LOGISTIC REGRESSION MODELS; ORGANOCHLORINE PESTICIDES; POLYCHLORINATED BIPHENYL (PCBS);

NEURODEGENERATIVE DISEASES;

CHLORPHENOTANE; CIS NONACHLOR HEXACHLOROBENZENE; HEXACHLOROBENZENE; ORGANOCHLORINE PESTICIDE; POLYCHLORINATED BIPHENYL; UNCLASSIFIED DRUG;

CONCENTRATION (COMPOSITION); DISEASE PREVALENCE; METABOLITE; ORGANOCHLORINE; PCB; POLLUTION EXPOSURE; PUBLIC HEALTH;

AGED; ALZHEIMER DISEASE; ARTICLE; BLOOD LEVEL; BLOOD SAMPLING; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DEMENTIA; DISEASE ASSOCIATION; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PREVALENCE; PRIORITY JOURNAL; RELIABILITY; SCORING SYSTEM; SENSITIVITY ANALYSIS; VERY ELDERLY;

CANADA;

ALZHEIMER DISEASE; DEMENTIA; EXPOSURE; ORGANOCHLORINE PESTICIDE; POLYCHLORINATED BIPHENYL;

AGED; AGED, 80 AND OVER; CANADA; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DEMENTIA; FEMALE; HUMANS; HYDROCARBONS, CHLORINATED; LOGISTIC MODELS; MALE; PESTICIDES; POLYCHLORINATED BIPHENYLS; PREVALENCE;

EID: 84900868492     PISSN: 01604120     EISSN: 18736750     Source Type: Journal    
DOI: 10.1016/j.envint.2014.04.016     Document Type: Article

References (36)

1. Baldi I., Lebailly P., Mohammed-Brahim B., Letenneur L., Dartigues J.F., Brochard P. Neurodegenerative diseases and exposure to pesticides in the elderly. Am J Epidemiol 2003, 157:409-414.
2. Chouliaras L., Sierksma A.S., Kenis G., Prickaerts J., Lemmens M.A., Brasnjevic I., et al. Gene-environment interaction research and transgenic mouse models of Alzheimer's disease. Int J Alzheimers Dis 2010, [pii: 859101]. 10.4061/2010/859101.
3. Fitzgerald E.F., Belanger E.E., Gomez M.I., Cayo M., McCaffrey R.J., Seegal R.F., et al. Polychlorinated biphenyl exposure and neuropsychological status among older residents of upper Hudson River communities. Environ Health Perspect 2008, 116:209-215.
4. Gauthier E., Fortier I., Courchesne F., Pepin P., Mortimer J., Gauvreau D. Environmental pesticide exposure as a risk factor for Alzheimer's disease: a case-control study. Environ Res 2001, 86:37-45.
5. Haase R.F., McCaffrey R.J., Santiago-Rivera A.L., Morse G.S., Tarbell A. Evidence of an age-related threshold effect of polychlorinated biphenyls (PCBs) on neuropsychological functioning in a Native American population. Environ Res 2009, 109:73-85.
6. Hastie T.J., Tibshirani R.J. Generalized Additive Models 1990, Chapman and Hall, New York.
7. Hayden K.M., Norton M.C., Darcey D., Ostbye T., Zandi P.P., Breitner J.C., et al. Occupational exposure to pesticides increases the risk of incident AD: the Cache County study. Neurology 2010, 74:1524-1530.
8. Hornung R.W., Reed L.D. Estimation of average concentration in the presence of nondetectable values. Appl Occup Environ Hyg 1990, 5:48-51.
9. Kodavanti P.R. Neurotoxicity of persistent organic pollutants: possible mode(s) of action and further considerations. Dose Response 2005, 3:273-305.
10. Li Q.Q., Loganath A., Chong Y.S., Tan J., Obbard J.P. Persistent organic pollutants and adverse health effects in humans. J Toxicol Environ Health A 2006, 69:1987-2005.
11. Lin K.C., Guo N.W., Tsai P.C., Yang C.Y., Guo Y.L. Neurocognitive changes among elderly exposed to PCBs/PCDFs in Taiwan. Environ Health Perspect 2008, 116:184-189.
12. Lindsay J., Sykes E., McDowell I., Verreault R., Laurin D. More than the epidemiology of Alzheimer's disease: contributions of the Canadian Study of Health and Aging. Can J Psychiatry 2004, 49:83-91.
13. Maloney B., Sambamurti K., Zawia N., Lahiri D.K. Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model. Curr Alzheimer Res 2012, 9:589-599.
14. Mariussen E., Fonnum F. Neurochemical targets and behavioral effects of organohalogen compounds: an update. Crit Rev Toxicol 2006, 36:253-289.
15. Marques S.C., Oliveira C.R., Pereira C.M., Outeiro T.F. Epigenetics in neurodegeneration: a new layer of complexity. Prog Neuropsychopharmacol Biol Psychiatry 2011, 35:348-355.
16. McLeod D., Arnott B., Gaudreault N., Boudreau S., Sevigny P. A comparison of two methods for routine, accurate determination of apolipoprotein E genotypes. Alzheimers Rep 1998, 1:211-215.
17. Medehouenou T.C.M., Ayotte P., Carmichael P.H., Kroger E., Verreault R., Lindsay J., et al. Polychlorinated biphenyls and organochlorine pesticides in plasma of older Canadians. Environ Res 2011, 111:1313-1320.
18. Mutter J., Curth A., Naumann J., Deth R., Walach H. Does inorganic mercury play a role in Alzheimer's disease? A systematic review and an integrated molecular mechanism. J Alzheimers Dis 2010, 22:357-374.
19. Parrón T., Requena M., Hernández A.F., Alarcon R. Association between environmental exposure to pesticides and neurodegenerative diseases. Toxicol Appl Pharmacol 2011, 256:379-385.
20. Phillips D.L., Pirkle J.L., Burse V.W., Bernert J.T., Henderson L.O., Needham L.L. Chlorinated hydrocarbon levels in human serum: effects of fasting and feeding. Arch Environ Contam Toxicol 1989, 18:495-500.
21. Querfurth H.W., LaFerla F.M. Alzheimer's disease. N Engl J Med 2010, 362:329-344.
22. Quinn C.L., Wania F. Understanding differences in the body burden-age relationships of bioaccumulating contaminants based on population cross sections versus individuals. Environ Health Perspect 2012, 120:554-559.
23. Raaschou-Nielsen O., Pavuk M., Leblanc A., Dumas P., Philippe Weber J., Olsen A., et al. Adipose organochlorine concentrations and risk of breast cancer among postmenopausal Danish women. Cancer Epidemiol Biomarkers Prev 2005, 14:67-74.
24. Richardson J.R., Roy A., Shalat S.L., von Stein R.T., Hossain M.M., Buckley B., et al. Elevated serum pesticide levels and risk for Alzheimer disease. JAMA Neurol 2014, 71:284-290.
25. Ritter R., Scheringer M., MacLeod M., Moeckel C., Jones K.C., Hungerbuhler K. Intrinsic human elimination half-lives of polychlorinated biphenyls derived from the temporal evolution of cross-sectional biomonitoring data from the United Kingdom. Environ Health Perspect 2011, 119:225-231.
26. Sanders T., Liu Y., Buchner V., Tchounwou P.B. Neurotoxic effects and biomarkers of lead exposure: a review. Rev Environ Health 2009, 24:15-45.
27. Schantz S.L., Gasior D.M., Polverejan E., McCaffrey R.J., Sweeney A.M., Humphrey H.E., et al. Impairments of memory and learning in older adults exposed to polychlorinated biphenyls via consumption of Great Lakes fish. Environ Health Perspect 2001, 109:605-611.
28. Schisterman E.F., Whitcomb B.W., Louis G.M., Louis T.A. Lipid adjustment in the analysis of environmental contaminants and human health risks. Environ Health Perspect 2005, 113:853-857.
29. Seegal R.F., Fitzgerald E.F., Hills E.A., Wolff M.S., Haase R.F., Todd A.C., et al. Estimating the half-lives of PCB congeners in former capacitor workers measured over a 28-year interval. J Expo Sci Environ Epidemiol 2011, 21:234-246.
30. Steenland K., Hein M.J., Cassinelli R.T., Prince M.M., Nilsen N.B., Whelan E.A., et al. Polychlorinated biphenyls and neurodegenerative disease mortality in an occupational cohort. Epidemiology 2006, 17:8-13.
31. The Canadian Study of Health and Aging The Canadian Study of Health and Aging: risk factors for Alzheimer's disease in Canada. Neurology 1994, 44:2073-2080.
32. The Canadian Study of Health and Aging Working Group Canadian study of health and aging: study methods and prevalence of dementia. CMAJ 1994, 150:899-913.
33. Troster A.I., Ruff R.M., Watson D.P. Dementia as a neuropsychological consequence of chronic occupational exposure to polychlorinated biphenyls (PCBs). Arch Clin Neuropsychol 1991, 6:301-318.
34. van Buuren S. Multiple imputation of discrete and continuous data by fully conditional specification. Stat Methods Med Res 2007, 16:219-242.
35. van Wendel de Joode B., Wesseling C., Kromhout H., Monge P., Garcia M., Mergler D. Chronic nervous-system effects of long-term occupational exposure to DDT. Lancet 2001, 357:1014-1016.
36. Zaganas I., Kapetanaki S., Mastorodemos V., Kanavouras K., Colosio C., Wilks M.F., et al. Linking pesticide exposure and dementia: what is the evidence?. Toxicology 2013, 307:3-11.