Reconstructing a B-cell clonal lineage. II. Mutation, selection, and affinity maturation

Frontiers in Immunology

Volumn 5, Issue APR, 2014, Pages

  Kepler, Thomas B ^a,b   Munshaw, Supriya ^c   Wiehe, Kevin ^d   Zhang, Ruijun ^d   Yu, Jae Sung ^d   Woods, Christopher W ^d   Denny, Thomas N ^d   Tomaras, Georgia D ^d   Alam, S Munir ^d   Moody, M Anthony ^c,d   Kelsoe, Garnett ^d   Liao, Hua Xin ^d   Haynes, Barton F ^d  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Boston University   (United States)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Antibody affinity maturation; Antibody selection; Experimental influenza infection; Phylogenetics; Somatic hypermutation

Indexed keywords

CD14 ANTIGEN; CD16 ANTIGEN; CD19 ANTIGEN; CD20 ANTIGEN; CD27 ANTIGEN; CD3 ANTIGEN; CD38 ANTIGEN; IMMUNOGLOBULIN A; IMMUNOGLOBULIN D; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN M; INFLUENZA VIRUS HEMAGGLUTININ;

ANTIBODY AFFINITY; ANTIBODY RESPONSE; ARTICLE; CELL LINEAGE; CELL MATURATION; CODON; DNA SEQUENCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE SEQUENCE; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN GENE; INFLUENZA; INFLUENZA A (H3N2); PHYLOGENY; POLYMERASE CHAIN REACTION; PRE B LYMPHOCYTE; SOMATIC HYPERMUTATION; VIRUS SHEDDING;

EID: 84900844918     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2014.00170     Document Type: Article

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