Increased virulence of Mycobacterium tuberculosis H37Rv overexpressing LipY in a murine model

Tuberculosis

Volumn 94, Issue 3, 2014, Pages 252-261

  Singh, Vipul K ^a   Srivastava, Mrigank ^a   Dasgupta, Arunava ^a   Singh, Mohan P ^b   Srivastava, Ranjana ^a   Srivastava, Brahm S ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b VEER BAHADUR SINGH PURVANCHAL UNIVERSITY   (India)

Author keywords

Immunization; LipY; Mycobacteriun tuberculosis; Overexpression; Protection; Rv3097c; Virulence

Indexed keywords

INTERLEUKIN 10; RECOMBINANT ANTIGEN; RECOMBINANT LIPASE ANTIGEN; TRIACYLGLYCEROL LIPASE; UNCLASSIFIED DRUG; VACCINE; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; CARBOXYLESTERASE; CYTOKINE; HSAD PROTEIN, MYCOBACTERIUM TUBERCULOSIS; HYDROLASE; LIPY PROTEIN, MYCOBACTERIUM TUBERCULOSIS; RECOMBINANT PROTEIN; VIRULENCE FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATTENUATION; BACTERIAL INFECTION; BACTERIAL LOAD; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CONTROLLED STUDY; DENDRITIC CELL; FEMALE; GENE OVEREXPRESSION; HOST; IMMUNE RESPONSE; IMMUNE STATUS; IMMUNIZATION; LUNG; LYMPHOID ORGAN; MACROPHAGE; MORPHOLOGY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SPLENOMEGALY; T LYMPHOCYTE; TH1 CELL; TH17 CELL; WEIGHT REDUCTION; ANIMAL; BAGG ALBINO MOUSE; CELLULAR IMMUNITY; DISEASE MODEL; ENZYMOLOGY; IMMUNOLOGY; KAPLAN MEIER METHOD; LUNG TUBERCULOSIS; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PROCEDURES; SPLEEN; T LYMPHOCYTE SUBPOPULATION; VACCINATION; VIRULENCE;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL LOAD; BACTERIAL PROTEINS; CARBOXYLIC ESTER HYDROLASES; CYTOKINES; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FEMALE; HYDROLASES; IMMUNITY, CELLULAR; KAPLAN-MEIER ESTIMATE; LIPASE; LUNG; MACROPHAGES; MICE, INBRED BALB C; MYCOBACTERIUM TUBERCULOSIS; RECOMBINANT PROTEINS; SPLEEN; T-LYMPHOCYTE SUBSETS; TUBERCULOSIS, PULMONARY; VACCINATION; VIRULENCE; VIRULENCE FACTORS;

EID: 84900834063     PISSN: 14729792     EISSN: 1873281X     Source Type: Journal    
DOI: 10.1016/j.tube.2014.02.001     Document Type: Article

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