LC-MS analysis of polyclonal IgGs using IdeS enzymatic proteolysis for oxidation monitoring

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 961, Issue , 2014, Pages 1-4

  Leblanc, Yann ^a   Romanin, Marie ^a   Bihoreau, Nicolas ^a   Chevreux, Guillaume ^a  

^a LFB Biotechnologies   (France)

Author keywords

IdeS; IgG; IVIG; Mass spectrometry; Oxidation

Indexed keywords

AMINO ACIDS; CHROMATOGRAPHY; MASS SPECTROMETRY;

ENZYMATIC PROTEOLYSIS; IDES; IVIG; LC-MS ANALYSIS; LIQUID SOLUTION; OXIDATIVE STATUS; STABILITY STUDY; STRESS CONDITION;

OXIDATION;

BIPHENYL; IMMUNOGLOBULIN; IMMUNOGLOBULIN FC FRAGMENT; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; IMMUNOGLOBULIN G4; METHIONINE; BACTERIAL PROTEIN; CYSTEINE PROTEINASE; MAC-1-LIKE PROTEIN, STREPTOCOCCUS;

ARTICLE; CHROMATOFOCUSING; GLYCOLYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; OXIDATION; OXIDATIVE STRESS; PEPTIDE MAPPING; PRIORITY JOURNAL; PROTEIN DEGRADATION; ULTRAVIOLET RADIATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; OXIDATION REDUCTION REACTION; PROCEDURES; STANDARDS;

BACTERIAL PROTEINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE PROTEASES; HUMANS; IMMUNOGLOBULIN FC FRAGMENTS; IMMUNOGLOBULIN G; IMMUNOGLOBULINS, INTRAVENOUS; MASS SPECTROMETRY; OXIDATION-REDUCTION; PROTEOLYSIS;

EID: 84900806505     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2014.04.053     Document Type: Article

References (14)

1. Darabi K., Abdel-Wahab O., Dzik W.H. Transfusion (Paris) 2006, 46:741.
2. Hartung H.P., Mouthon L., Ahmed R., Jordan S., Laupland K.B., Jolles S. Clin. Exp. Immunol. 2009, 158(Suppl. 1):23.
3. Shacter E. Drug Metab. Rev. 2000, 32:307.
4. Hu M.L., Tappel A.L. Photochem. Photobiol. 1992, 56:357.
5. Duenas E.T., Keck R., De Vos A., Jones A.J., Cleland J.L. Pharm. Res. 2001, 18:1455.
6. Chevreux G., Tilly N., Bihoreau N. Anal. Biochem. 2011, 415:212.
7. von Pawel-Rammingen U., Johansson B.P., Bjorck L. EMBO J. 2002, 21:1607.
8. Goetze A.M., Zhang Z., Liu L., Jacobsen F.W., Flynn G.C. Mol. Immunol. 2011, 49:338.
9. Ren D., Pipes G., Xiao G., Kleemann G.R., Bondarenko P.V., Treuheit M.J., Gadgil H.S. J. Chromatogr. A 2008, 1179:198.
10. Jefferis R., Lefranc M.P. MAbs 2009, 1:332.
11. Dard P., Lefranc M.P., Osipova L., Sanchez-Mazas A. Eur. J. Hum. Genet. 2001, 9:765.
12. Liu H., Gaza-Bulseco G., Zhou L. J. Am. Soc. Mass Spectrom. 2009, 20:525.
13. Pan H., Chen K., Chu L., Kinderman F., Apostol I., Huang G. Protein Sci. 2009, 18:424.
14. Chumsae C., Gaza-Bulseco G., Sun J., Liu H. J. Chromatogr. B: Analyt. Technol. Biomed. Life Sci. 2007, 850:285.