Baicalin attenuates transforming growth factor-β1-induced human pulmonary artery smooth muscle cell proliferation and phenotypic switch by inhibiting hypoxia inducible factor-1α and aryl hydrocarbon receptor expression

Journal of Pharmacy and Pharmacology

Volumn 66, Issue 10, 2014, Pages 1469-1477

  Huang, Shian ^a   Chen, Puwen ^a   Shui, Xiaorong ^a   He, Yuan ^a   Wang, Heyong ^b   Zheng, Jing ^a,c   Zhang, Liangqing ^a   Li, Jianwen ^a   Xue, Yiqiang ^a   Chen, Can ^a   Lei, Wei ^a  

^a GUANGDONG MEDICAL UNIVERSITY   (China)

^b TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

aryl hydrocarbon receptor; baicalin; hypoxia inducible factor 1 ; pulmonary arterial smooth muscle cell; transforming growth factor

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BAICALIN; FLAVONOID; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PLANT EXTRACT; TRANSFORMING GROWTH FACTOR BETA1;

CELL CULTURE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; HUMAN; METABOLISM; PHENOTYPE; PULMONARY ARTERY; SCUTELLARIA BAICALENSIS; SMOOTH MUSCLE CELL;

CELL PROLIFERATION; CELLS, CULTURED; FLAVONOIDS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MYOCYTES, SMOOTH MUSCLE; PHENOTYPE; PLANT EXTRACTS; PULMONARY ARTERY; RECEPTORS, ARYL HYDROCARBON; SCUTELLARIA BAICALENSIS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84900674126     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/jphp.12273     Document Type: Article

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